keyword
https://read.qxmd.com/read/38492813/outcome-after-modern-proton-beam-therapy-in-childhood-craniopharyngioma-results-of-the-prospective-registry-study-kiproreg
#1
JOURNAL ARTICLE
M Bischoff, D Ahmad Khalil, S Frisch, C M Bäcker, S Peters, C Friedrich, S Tippelt, R-D Kortmann, B Bison, H L Müller, B Timmermann
BACKGROUND: Craniopharyngiomas (CPs) are rare tumours of the sellar region often leading to significant comorbidities due to their close proximity to critical structures. Aim of this study was to analyse survival outcome and late toxicities after surgery and proton beam therapy (PBT) in childhood CPs. PATIENTS AND METHODS: Within the prospective XXXX study (XXXX), data of 74 childhood patients with CP, receiving PBT between 08/2013-06/2022 were eligible. Late toxicities were analysed according to the grading system of CTCAE 4...
March 14, 2024: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/38492526/oncological-outcomes-of-intraperitoneal-chemotherapy-in-advanced-ovarian-cancer-brca-mutation-role
#2
JOURNAL ARTICLE
Pablo Padilla-Iserte, Maria Iváñez, Juan Carlos Muruzabal, Rafael Navarro, Berta Díaz-Feijoo, Sara Iacoponi, Virginia García-Pineda, Cristina Díaz, Jesús Utrilla-Layna, Antonio Gil-Moreno, Anna Serra, Juan Gilabert-Estellés, Cristina Martínez Canto, Álvaro Tejerizo, Víctor Lago, José Miguel Cárdenas-Rebollo, Santiago Domingo
INTRODUCTION: The knowledge of BRCA status offers a chance to evaluate the role of the intraperitoneal route in patients selected by biomolecular profiles after primary cytoreduction surgery in advanced ovarian cancer. MATERIALS AND METHODS: We performed a retrospective, multicenter study to assess oncological outcomes depending on adjuvant treatment (intraperitoneal [IP] vs intravenous [IV]) and BRCA status (BRCA1/2 mutated vs. BRCA wild type [WT]). The primary endpoint was to determine progression-free survival...
March 9, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38492474/fertility-potential-and-safety-assessment-of-residual-ovarian-cortex-in-young-women-diagnosed-with-epithelial-borderline-and-early-stage-malignant-ovarian-tumors
#3
JOURNAL ARTICLE
L Cacciottola, A Camboni, E Gatti, E Marbaix, M Vignali, J Donnez, M M Dolmans
OBJECTIVE: To establish the safety and quality of ovarian cortex surrounding epithelial ovarian tumors in women eligible for fertility-sparing surgery by identifying occult malignant lesions and characterizing the ovarian follicle pool. METHODS: Multicentric retrospective study of 48 subjects (15-45 years), diagnosed with borderline ovarian tumors (BOTs) or early-stage epithelial ovarian cancers (EOCs) and eligible for fertility-sparing surgery. Histological samples of ovarian cortex surrounding tumors were analyzed to characterize the follicle pool, find any occult malignant lesion using tumor-specific markers (cytokeratin 7 and mucin 1), and quantify tumor-infiltrating lymphocytes (TILs) by CD3 and tumor associated macrophages (TAMs) by CD68...
March 15, 2024: Gynecologic Oncology
https://read.qxmd.com/read/38492275/regoma-oss-a-large-italian-multicenter-prospective-observational-study-evaluating-the-efficacy-and-safety-of-regorafenib-in-patients-with-recurrent-glioblastoma
#4
JOURNAL ARTICLE
M Caccese, I Desideri, V Villani, M Simonelli, M Buglione, S Chiesa, E Franceschi, P Gaviani, I Stasi, C Caserta, S Brugnara, I Lolli, E Bennicelli, P Bini, A S Cuccu, S Scoccianti, M Padovan, S Gori, A Bonetti, P Giordano, A Pellerino, F Gregucci, N Riva, S Cinieri, V Internò, M Santoni, G Pernice, C Dealis, L Stievano, F Paiar, G Magni, G L De Salvo, V Zagonel, G Lombardi
BACKGROUND: In the randomized phase II REGOMA trial, regorafenib showed promising activity in patients with recurrent glioblastoma. We conducted a large, multicenter, prospective, observational study to confirm the REGOMA data in a real-world setting. PATIENTS AND METHODS: The major inclusion criteria were histologically confirmed diagnosis of glioblastoma according to the World Health Organization (WHO) 2016 classification and relapse after radiotherapy with concurrent/adjuvant temozolomide treatment, good performance status [Eastern Cooperative Oncology Group performance status (ECOG PS 0-1)] and good liver function...
March 15, 2024: ESMO Open
https://read.qxmd.com/read/38492259/oncologic-safety-of-breast-conserving-surgery-after-neoadjuvant-chemotherapy-in-patients-with-multiple-ipsilateral-breast-cancer-a-retrospective-multi-institutional-cohort-study
#5
JOURNAL ARTICLE
Élise Di Lena, Stephanie M Wong, Ericka Iny, Sarah Mashal, Mark Basik, Jean-François Boileau, Karyne Martel, Miranda Addie Bassel, Sarkis Meterissian, Ipshita Prakash
INTRODUCTION: The recent ACOSOG Z11102 trial demonstrated low recurrence rates with breast conserving surgery (BCS) in women with multiple ipsilateral breast cancers (MIBC). Questions remain regarding the oncologic safety of BCS in women with MIBC receiving neoadjuvant chemotherapy (NAC). METHODS: We conducted a retrospective cohort study of adult patients who underwent BCS following NAC for stage I-III breast cancer from 2012 to 2021 at two academic centers...
March 12, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38492066/salivary-gland-type-cancers-cross-organ-demographics-of-a-rare-cancer
#6
JOURNAL ARTICLE
Aika Tanzawa, Kengo Saito, Masayuki Ota, Koji Takahashi, Izumi Ohno, Toyoyuki Hanazawa, Katsuhiro Uzawa, Yuichi Takiguchi
BACKGROUND: Salivary gland-type cancers (SGTCs) are histologically heterogeneous and can affect organs other than the salivary glands. Some tumors outside the salivary glands are diagnosed on their unique histological characteristics. Comprehensive cross-organ studies on SGTCs are limited. METHODS: We retrospectively analyzed the data of patients with salivary duct carcinoma (SDC), adenoid cystic carcinoma (AdCC), mucoepidermoid carcinoma (MEC), epithelial-myoepithelial carcinoma (EMC), acinic cell carcinoma (AcCC), and polymorphous adenocarcinoma (PAC) who visited our institution between 2009 and 2019...
March 16, 2024: International Journal of Clinical Oncology
https://read.qxmd.com/read/38492057/defining-the-learning-curve-for-robotic-pancreaticoduodenectomy-for-a-single-surgeon-following-experience-with-laparoscopic-pancreaticoduodenectomy
#7
JOURNAL ARTICLE
Isabel DeLaura, Jeremy Sharib, John M Creasy, Samuel I Berchuck, Dan G Blazer, Michael E Lidsky, Kevin N Shah, Sabino Zani
Robotic pancreaticoduodenectomy (RPD) has a learning curve of approximately 30-250 cases to reach proficiency. The learning curve for laparoscopic pancreaticoduodenectomy (LPD) at Duke University was previously defined as 50 cases. This study describes the RPD learning curve for a single surgeon following experience with LPD. LPD and RPD were retrospectively analyzed. Continuous pathologic and perioperative metrics were compared and learning curve were defined with respect to operative time using CUSUM analysis...
March 16, 2024: Journal of Robotic Surgery
https://read.qxmd.com/read/38492016/excluding-external-iliac-node-irradiation-during-neoadjuvant-radiotherapy-decreases-lower-intestinal-toxicity-without-compromising-efficacy-in-t4b-rectal-cancer-patients-with-tumours-involving-the-anterior-structures
#8
JOURNAL ARTICLE
Anchuan Li, Miaobin Mao, Runfan Chen, Pan Chi, Ying Huang, Junxin Wu, Benhua Xu
PURPOSE: To explore the impact of excluding the external iliac node (EIN) from the clinical target volume (CTV) during preoperative radiotherapy in T4b rectal cancer with anterior structure invasion. METHODS: We retrospectively identified 132 patients with T4b rectal cancer involving the anterior structures who received radiotherapy followed by surgery between May 2010 and June 2019. Twenty-nine patients received EIN irradiation (EIN group), and 103 did not (NEIN group)...
March 16, 2024: Discover. Oncology
https://read.qxmd.com/read/38491738/engaging-patients-in-designing-a-transmural-allied-health-pathway-a-qualitative-exploration-of-hospital-to-home-transitions
#9
JOURNAL ARTICLE
Juul W M van Grootel, Romain J Collet, Mel E Major, Suzanne Wiertsema, Hanneke van Dongen, Marike van der Leeden, Edwin Geleijn, Raymond Ostelo, Marike van der Schaaf
INTRODUCTION: The transition from hospital to home is often suboptimal, resulting in patients not receiving the necessary allied healthcare after discharge. This may, in turn, lead to delayed recovery, a higher number of readmissions, more emergency department visits and an increase in mortality and healthcare costs. This study aimed to gain insight into patients' experiences, perceptions, and needs regarding hospital-to-home transition, focusing on allied healthcare as a first step towards the development of a transitional integrated allied healthcare pathway for patients with complex care needs after hospital discharge...
April 2024: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://read.qxmd.com/read/38491445/equity-in-the-recovery-of-elective-and-oncological-surgery-volumes-after-the-covid-19-lockdown-a-multicentre-cohort-study-in-italy
#10
JOURNAL ARTICLE
Chiara Di Girolamo, Roberta Onorati, Tania Landriscina, Roberto Gnavi, Giulia Cesaroni, Enrico Calandrini, Lucia Bisceglia, Caterina Fanizza, Teresa Spadea
BACKGROUND: The COVID-19 pandemic has had, and still has, a profound impact on national health systems, altering trajectories of care and exacerbating existing inequalities in health. Postponement of surgeries and cancellation of elective surgical procedures have been reported worldwide. In Italy, the lock-down measures following the COVID-19 pandemic caused cancellations of surgical procedures and important backlogs; little is known about potential social inequalities in the recovery process that occurred during the post-lockdown period...
March 15, 2024: International Journal for Equity in Health
https://read.qxmd.com/read/38491404/radiation-therapy-for-retroperitoneal-sarcoma-practice-patterns-in-north-america
#11
JOURNAL ARTICLE
Samantha M Ruff, Victor Heh, David J Konieczkowski, Amblessed Onuma, Hayley M Dunlop, Alex C Kim, Valerie P Grignol, Carlo M Contreras, Timothy M Pawlik, Raphael Pollock, Joal D Beane
BACKGROUND: The addition of radiation therapy (RT) to surgery in retroperitoneal sarcoma (RPS) remains controversial. We examined practice patterns in the use of RT for patients with RPS over time in a large, national cohort. METHODS: Patients in the National Cancer Database (2004-2017) who underwent resection of RPS were included. Trends over time for proportions were calculated using contingency tables with Cochran-Armitage Trend test. RESULTS: Of 7,485 patients who underwent resection, 1,821 (24...
March 16, 2024: Radiation Oncology
https://read.qxmd.com/read/38491312/retrospective-evaluation-of-the-prognostic-value-of-histological-growth-pattern-in-patients-with-colorectal-peritoneal-metastases-undergoing-curative-intent-cytoreductive-surgery
#12
JOURNAL ARTICLE
Leonel Kamdem, Antoine El Asmar, Pieter Demetter, Ismael Coulibaly Zana, Charif Khaled, Francesco Sclafani, Vincent Donckier, Peter Vermeulen, Gabriel Liberale
BACKGROUND: Two distinct histological growth patterns (HGPs) were described in patients with peritoneal metastasis of colorectal cancer origin (PMCRC) with limited Peritoneal Cancer Index (PCI) ≤ 6 who did not receive neoadjuvant chemotherapy (NAC) and were treated with cytoreductive surgery (CRS) ± hyperthermic intraperitoneal chemotherapy (HIPEC): pushing HGP (P-HGP) and infiltrating HGP (I-HGP). Patients with dominant P-HGP (> 50%) had significantly better disease-free survival (DFS) and overall survival (OS)...
March 15, 2024: Annals of Surgical Oncology
https://read.qxmd.com/read/38490885/robotic-assisted-pediatric-thoracic-and-abdominal-tumor-resection-an-initial-multi-center-review
#13
JOURNAL ARTICLE
Wendy Jo Svetanoff, Michela Carter, Karen A Diefenbach, Marc Michalsky, Daniel DaJusta, Edward Gong, Timothy B Lautz, Jennifer H Aldrink
INTRODUCTION: Robotic-assisted minimally invasive surgery (RA-MIS) for tumor resection is an emerging technology in the pediatric population with significant promise but unproven safety and feasibility. METHODS: A multi-center retrospective review of patients ≤18 years undergoing RA-MIS tumor resection from December 2015-March 2023 was performed. Patient demographics, perioperative variables, and complication rates were analyzed. RESULTS: Thirty-nine procedures were performed on 38 patients (17 thoracic, 22 abdominal); 37% female and 68% non-Hispanic White...
February 26, 2024: Journal of Pediatric Surgery
https://read.qxmd.com/read/38490882/incidence-and-risk-factors-for-chyle-leaks-after-neuroblastic-tumor-resection-a-systematic-review-of-published-studies
#14
REVIEW
Arimatias Raitio, Paul D Losty
BACKGROUND: Chyle leakage/ascites after surgical resection of neuroblastic tumors may delay the start of chemotherapy and worsen prognosis. Previous studies have reported a highly variable incidence and risk factors remain largely unknown. This study aims to analyze the true incidence of chyle leaks and ascites and seeks to identify risk factors and optimal treatment strategies. METHODS: Medline/Embase databases were searched according to PRISMA guidelines. Literature reviews, case reports, and non-English papers were excluded...
February 26, 2024: Journal of Pediatric Surgery
https://read.qxmd.com/read/38490619/disparities-in-access-to-multidisciplinary-cancer-consultations-and-treatment-for-early-stage-non-small-cell-lung-cancer-patients-a-seer-medicare-analysis
#15
JOURNAL ARTICLE
You-Chi Liu, Rachel O Schmidt, Nirav S Kapadia, Joseph D Phillips, Erika L Moen
PURPOSE: Disparities in access to multidisciplinary cancer consultations (MDCc) persist, and the role of physician relationships remains understudied. This study examined the extent to which multilevel factors, including patient characteristics and patient-sharing network measures reflecting the structure of physician relationships, are associated with MDCc and receipt of stereotactic body radiation therapy (SBRT) versus surgery among early-stage non-small cell lung cancer (NSCLC) patients...
March 13, 2024: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/38490442/ultrasound-guided-resection-of-high-grade-gliomas-a-single-arm-meta-analysis
#16
REVIEW
Lucca B Palavani, Márcio Yuri Ferreira, Pedro G L B Borges, Luis Bandeira, Gabriel da Silva Semione, Miguel V Almeida, Gabriel Verly, Allan Dias Polverini, Filipi Fim Andreão, Raphael Camerotte, Christian Ferreira, Wellingson Paiva, Raphael Bertani, John Boockvar
BACKGROUND: High-grade gliomas (HGG) present a challenge in neuro-oncology, often necessitating surgical resection for optimal management. Ultrasound (US) holds promise in achieving better Gross Total Resection (GTR) and improving outcomes. This meta-analysis systematically evaluates literature providing robust evidence on the use of intraoperative Ultrasonography (iUSG) in HGG resection. METHODS: Following PRISMA guidelines a comprehensive search was made across PubMed, Embase, Cochrane, and Web of Science utilized terms related to iUSG for HGG resection...
March 13, 2024: World Neurosurgery
https://read.qxmd.com/read/38489819/therapeutic-approaches-for-spinal-synovial-sarcoma-a-comprehensive-review-of-the-literature
#17
JOURNAL ARTICLE
Aroosa Zamarud, Syeda Shahnoor, Adeena Maryyum, Abdul Moiz Khan, Khawaja Muthammir Hassan, Aamna Ijaz, Rahman Sayed, Kelly Yoo, David J Park, Steven D Chang
OBJECTIVE: Synovial sarcoma (SS) is a relatively rare type of soft-tissue sarcoma that is commonly treated with surgery, radiation, chemotherapy, and palliative care. Stereotactic radiosurgery (SRS) is an emerging approach that shows promise in treating CNS conditions, but it has not been studied for SS. The authors present a systematic review that explores the effectiveness of different treatments, with a focus on SRS, for managing spinal SS. METHODS: A systematic PubMed search was conducted that covered studies from 1964 to 2022, yielding 70 relevant studies...
March 15, 2024: Journal of Neurosurgery. Spine
https://read.qxmd.com/read/38489811/pediatric-brain-tumors-in-sub-saharan-africa-a-systematic-review-and-meta-analysis
#18
JOURNAL ARTICLE
Arsene Daniel Nyalundja, Ulrick Sidney Kanmounye, Claire Karekezi, Tsegazeab Laeke, Nqobile Thango, James A Balogun
OBJECTIVE: Brain tumors are a global problem, leading to higher cancer-related morbidity and mortality rates in children. Despite the progressive though slow advances in neuro-oncology care, research, and diagnostics in sub-Saharan Africa (SSA), the epidemiological landscape of pediatric brain tumors (PBTs) remains underestimated. This study aimed to systematically analyze the distribution of PBT types in SSA. METHODS: Ovid Medline, Global Index Medicus, African Journals Online, Google Scholar, and faculty of medicine libraries were searched for literature on PBTs in SSA published before October 29, 2022...
March 15, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38489558/indocyanine-green-fluorescence-applied-to-gynecologic-oncology-beyond-sentinel-lymph-node
#19
JOURNAL ARTICLE
M Loverro, N Bizzarri, F M Capomacchia, Rafał Watrowski, D Querleu, A Gioè, A Naldini, F Santullo, N Foschi, A Fagotti, G Scambia, F Fanfani
Indocyanine green (ICG), a well-known molecule employed in medicine for over five decades, has emerged as a versatile dye widely embraced across various surgical disciplines. In gynecologic oncology, its prevalent use revolves around the detection of sentinel lymph nodes. However, the true potential of ICG extends beyond this singular application, owing to its pragmatic utility, cost-effectiveness, and safety profile. Furthermore, ICG has been introduced in the theranostic landscape, marking a significant juncture in the evolution of its clinical utility...
March 15, 2024: International Journal of Surgery
https://read.qxmd.com/read/38488440/developing-a-conceptual-model-for-understanding-caregiving-experience-and-their-impacts-on-quality-of-life-for-chinese-breast-cancer-family-caregivers-a-qualitative-study
#20
JOURNAL ARTICLE
Chaoyue Gao, Min Li, Linfang Guo, Haoran Duan, Peili Zhang, Yongxia Ding
AIM: The purpose of this study was to understand the caregiving experiences of breast cancer family caregivers and explore the profound impacts of those experiences on their quality of life. DESIGN: A qualitative research method was used. METHODS: We extended invitations to 23 family caregivers of outpatients and inpatients receiving breast surgery and oncology treatments in Taiyuan, China, to participate in semi-structured interviews. The interviews were audio-recorded and transcribed verbatim...
March 2024: Nursing Open
keyword
keyword
4744
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.