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Corey S Davis, Scott Burris, Leo Beletsky, Ingrid Binswanger
The opioid overdose epidemic claims the lives of tens of thousands of Americans every year. Opioid overdose is reversible by the administration of naloxone, a pure antagonist now available in formulations specifically designed and labeled for layperson use. Despite broad support for layperson access to naloxone from professional organizations, health officials, and clinical experts, qualitative studies suggest that some providers have concerns about legal risks associated with naloxone prescribing, particularly co-prescribing naloxone to pain patients...
September 20, 2016: Substance Abuse
Elisabetta Basso
This paper aims to analyze Michel Foucault's position toward phenomenological psychology and psychopathology during the 1950s, in light of the new documentary sources available today. Our investigation is especially focused on one of the courses given by Foucault at the University of Lille between 1952 and 1954, namely, the course on "Binswanger and phenomenology" (1953-54). The analysis of this course, which was conceived by Foucault within the context of a philosophical reflection on the anthropological problem of psychopathology, will finally allow us to re-ascribe Foucault the place he deserves in the field of "philosophy of psychiatry"...
December 2016: Revue de Synthèse
Ingrid A Binswanger, Patrick J Blatchford, Simon J Forsyth, Marc F Stern, Stuart A Kinner
OBJECTIVES: People in prison may be at high risk for infectious diseases and have an elevated risk of death immediately after release compared with later; their risk of death is elevated for at least a decade after release. We compared rates, characteristics, and prison-related risk factors for infectious disease-related mortality among people released from prisons in Queensland, Australia, and Washington State, United States, regions with analogous available data. METHODS: We analyzed data from retrospective cohort studies of people released from prison in Queensland (1997-2007, n=37,180) and Washington State (1999-2009, n=76,208) and linked identifiers from each cohort to its respective national death index...
July 2016: Public Health Reports
Ralf Binswanger
The unique approach to dreams of Swiss psychoanalyst Fritz Morgenthaler (1919-1984) is presented and discussed. Although rarely discussed in the English-speaking psychoanalytic world, this approach is very alive in German-speaking countries. Focusing on the distinction between the remembered hallucinatory experience of dreamers and the event of telling dreams within psychoanalytic sessions, Morgenthaler made two major innovations: first, he proposed a new understanding and handling of associations to dreams, and second, he offered what he called dream diagnostics as an instrument with which to integrate both resistance and transference into clinical work with dreams...
July 2016: Psychoanalytic Quarterly
R Martín-Láez, N Valle-San Román, E M Rodríguez-Rodríguez, E Marco-de Lucas, J A Berciano Blanco, A Vázquez-Barquero
INTRODUCTION: Since its description five decades ago, the pathophysiology of idiopathic chronic adult hydrocephalus (iCAH) has been traditionally related to the effect that ventricular dilatation exerts on the structures surrounding the ventricular system. However, altered cerebral blood flow, especially a reduction in the CSF turnover rate, are starting to be considered the main pathophysiological elements of this disease. DEVELOPMENT: Compression of the pyramidal tract, the frontostriatal and frontoreticular circuits, and the paraventricular fibres of the superior longitudinal fasciculus have all been reported in iCAH...
June 10, 2016: Neurología: Publicación Oficial de la Sociedad Española de Neurología
Ulrike May
Warda and Strohmayer from Thuringia were among the first German physicians who developed an interest in Freuds theory and therapeutic method around 1900. Their contributions reflect the influence of Otto Binswanger, professor of psychiatry in Jena, a representative of the "psychological direction" in psychiatry which in the beginning was relatively receptive to Freud. The paper discusses their rapprochement to, and detachment from, the Freudian school, including also the work of a third young physician: Ludwig Binswanger, Otto's nephew, who was active in Jena at the same time...
2016: Luzifer-Amor: Zeitschrift Zur Geschichte der Psychoanalyse
Joseph W Frank, Cari Levy, Daniel D Matlock, Susan L Calcaterra, Shane R Mueller, Stephen Koester, Ingrid A Binswanger
OBJECTIVE : There is inadequate evidence of long-term benefit and growing evidence of the risks of chronic opioid therapy (COT). Opioid dose reduction, or opioid tapering, may reduce these risks but may also worsen pain and quality of life. Our objective was to explore patients' perspectives on opioid tapering. DESIGN : Qualitative study using in-person, semistructured interviews. SETTING AND PATIENTS : English-speaking, adult primary care patients (N = 24) in three Colorado health care systems. METHODS : Interviews were audio recorded, transcribed, and analyzed in ATLAS...
May 20, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Susan L Calcaterra, Anne D Drabkin, Sarah E Leslie, Reina Doyle, Stephen Koester, Joseph W Frank, Jennifer A Reich, Ingrid A Binswanger
BACKGROUND: Pain is a frequent symptom among patients in the hospital. Pain management is a key quality indicator for hospitals, and hospitalists are encouraged to frequently assess and treat pain. Optimal opioid prescribing, described as safe, patient-centered, and informed opioid prescribing, may be at odds with the priorities of current hospital care, which focuses on patient-reported pain control rather than the potential long-term consequences of opioid use. OBJECTIVE: We aimed to understand physicians' attitudes, beliefs, and practices toward opioid prescribing during hospitalization and discharge...
August 2016: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
Stéphanie Hostenbach, Miguel D'haeseleer, Ron Kooijman, Jacques De Keyser
In the normal central nervous system, endothelin-1 (ET-1) is found in some types of neurons, epithelial cells of the choroid plexus, and endothelial cells of microvessels, but it is usually not detectable in glial cells. However, in different pathological conditions, astrocytes adapting a reactive phenotype express high levels of ET-1 and its receptors, mainly the ETB receptor. ET-1 released by reactive astrocytes appears mainly to have neurodeleterious effects by mechanisms that include constriction of cerebral arterioles leading to impairment of the cerebral microcirculation, increase of blood brain barrier permeability, inflammation, excitotoxicity, impairment of fast axonal transport, and astrogliosis...
September 2016: Progress in Neurobiology
Danielle F Loeb, Elizabeth A Bayliss, Carey Candrian, Frank V deGruy, Ingrid A Binswanger
BACKGROUND: Complex patients are increasingly common in primary care and often have poor clinical outcomes. Healthcare system barriers to effective care for complex patients have been previously described, but less is known about the potential impact and meaning of caring for complex patients on a daily basis for primary care providers (PCPs). Our objective was to describe PCPs' experiences providing care for complex patients, including their experiences of health system barriers and facilitators and their strategies to enhance provision of effective care...
2016: BMC Family Practice
Gary A Rosenberg
Vascular cognitive impairment (VCI) is a heterogeneous group of diseases linked together by cerebrovascular disease. Treatment of VCI has been hindered by the lack of a coherent pathophysiological process that could provide molecular targets. Of the several forms of VCI, the small vessel disease form is both the most prevalent and generally has a progressive course. Binswanger's disease (BD) is the small vessel form of VCI that involves extensive injury to the deep white matter. Growing evidence suggests that there is disruption of the blood-brain barrier (BBB) secondary to an inflammatory state...
March 2016: Cellular and Molecular Neurobiology
Karsten Bartels, Ingrid A Binswanger, Christian J Hopfer
No abstract text is available yet for this article.
March 2016: Journal of Addiction Medicine
Sarah Larney, Michael Farrell
No abstract text is available yet for this article.
March 2016: Addiction
Andrea K Finlay, Alex H S Harris, Joel Rosenthal, Jessica Blue-Howells, Sean Clark, Jim McGuire, Christine Timko, Susan M Frayne, David Smelson, Elizabeth Oliva, Ingrid Binswanger
BACKGROUND: Pharmacotherapy - methadone, buprenorphine, or naltrexone - is an evidence-based treatment for opioid use disorder, but little is known about receipt of these medications among veterans involved in the justice system. The current study examines receipt of pharmacotherapy for opioid use disorder among veterans with a history of justice involvement at U.S. Veterans Health Administration (VHA) facilities compared to veterans with no justice involvement. METHODS: Using national VHA clinical and pharmacy records, we conducted a retrospective cohort study of veterans with an opioid use disorder diagnosis in fiscal year 2012...
March 1, 2016: Drug and Alcohol Dependence
Karsten Bartels, Lena M Mayes, Colleen Dingmann, Kenneth J Bullard, Christian J Hopfer, Ingrid A Binswanger
INTRODUCTION: Opioid-based analgesic therapy represents a cornerstone of pain management after surgery. The recent rise in opioid sales and opioid overdoses suggests it is important to maximize the safety of opioid prescribing after surgery. Given that patients may live with other family members in the home, safe storage and appropriate disposal of excess opioids after hospital discharge are necessary to prevent unintended secondary exposures. Identifying characteristics of patients who are likely to be prescribed excess opioids after surgery may enable more targeted prescription practices and safety interventions...
2016: PloS One
Ingrid A Binswanger, Adam J Gordon
No abstract text is available yet for this article.
2016: Substance Abuse
Andrea K Finlay, Matthew Stimmel, Jessica Blue-Howells, Joel Rosenthal, Jim McGuire, Ingrid Binswanger, David Smelson, Alex H S Harris, Susan M Frayne, Tom Bowe, Christine Timko
The Veterans Health Administration (VA) Health Care for Reentry Veterans (HCRV) program links veterans exiting prison with treatment. Among veterans served by HCRV, national VA clinical data were used to describe contact with VA health care, and mental health and substance use disorder diagnoses and treatment use. Of veterans seen for an HCRV outreach visit, 56 % had contact with VA health care. Prevalence of mental health disorders was 57 %; of whom 77 % entered mental health treatment within a month of diagnosis...
December 21, 2015: Administration and Policy in Mental Health
Joseph W Frank, Cari Levy, Susan L Calcaterra, Jason A Hoppe, Ingrid A Binswanger
Rates of opioid overdose and opioid-related emergency department (ED) visits have increased dramatically. Naloxone is an effective antidote to potentially fatal opioid overdose, but little is known about naloxone administration in ED settings. We examined trends and correlates of naloxone administration in ED visits nationally from 2000 to 2011. Using data from the National Hospital Ambulatory Medical Care Survey, we examined ED visits involving (1) the administration of naloxone or (2) a diagnosis of opioid overdose, abuse, or dependence...
June 2016: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
Zhiyou Cai, Chuanling Wang, Wenbo He, Hanjun Tu, Zhengang Tang, Ming Xiao, Liang-Jun Yan
Cerebral small vessel disease (CSVD) is a group of pathological processes with multifarious etiology and pathogenesis that are involved into the small arteries, arterioles, venules, and capillaries of the brain. CSVD mainly contains lacunar infarct or lacunar stroke, leukoaraiosis, Binswanger's disease, and cerebral microbleeds. CSVD is an important cerebral microvascular pathogenesis as it is the cause of 20% of strokes worldwide and the most common cause of cognitive impairment and dementia, including vascular dementia and Alzheimer's disease (AD)...
2015: Clinical Interventions in Aging
Susan L Calcaterra, Traci E Yamashita, Sung-Joon Min, Angela Keniston, Joseph W Frank, Ingrid A Binswanger
BACKGROUND: Chronic opioid therapy for chronic pain treatment has increased. Hospital physicians, including hospitalists and medical/surgical resident physicians, care for many hospitalized patients, yet little is known about opioid prescribing at hospital discharge and future chronic opioid use. OBJECTIVE: We aimed to characterize opioid prescribing at hospital discharge among 'opioid naïve' patients. Opioid naïve patients had not filled an opioid prescription at an affiliated pharmacy 1 year preceding their hospital discharge...
May 2016: Journal of General Internal Medicine
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