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mucinous cystadenoma

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https://www.readbyqxmd.com/read/29744127/virilization-of-a-postmenopausal-woman-by-a-mucinous-cystoadenoma
#1
Sara Alonso Díaz, Belén Vega Piñero, Lía Nattero Chávez, Ignacio Pinilla Pagnon, Andrés Ortiz-Flores, Manuel Luque-Ramírez
Objective: To describe the case of the most hyperandrogenaemic ovarian mucinous cystadenoma reported to date. Methods: We present the clinical, laboratory and radiologic findings in a patient with an unusual diagnosis according to age and the clinical behaviour of the tumour, as well as a review of relevant literature. Results: A 77-year-old women came to our consult because of fronto-parietal alopecia and an augmentation of the abdominal perimeter since 1 year ago...
January 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29738361/intraductal-papillary-mucinous-neoplasms-of-minor-salivary-glands-with-akt1-p-glu17lys-mutation
#2
Abbas Agaimy, Sarina K Mueller, Klaus Bumm, Heinrich Iro, Evgeny A Moskalev, Arndt Hartmann, Robert Stoehr, Florian Haller
The spectrum of low-grade intraductal papillary proliferations of the salivary glands is heterogenous, and reproducible morphologic diagnostic criteria have not yet been established. Recognized types are sialadenoma papilliferum, inverted ductal papilloma, and intraductal papilloma, but some lesions have been possibly included in the morphologic spectrum of cystadenoma or low-grade intraductal carcinomas. We herein present detailed morphologic, immunophenotypic, and genotypic features of 3 minor salivary gland neoplasms affecting 2 men (aged 65 and 71 y) and 1 woman (aged 78 y)...
May 5, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29731792/immunohistochemical-characterization-of-normal-ovary-and-common-epithelial-ovarian-neoplasm-with-a-monoclonal-antibody-to-cytokeratin-and-vimentin
#3
Ankita Goel, Nandam Mohan Rao, Vissa Santhi, Syam Sundar Byna, Bhavana Grandhi, Jyothi Conjeevaram
Background & Objective: The common epithelial ovarian tumors are classified into serous, mucinous, clear cell, endometrioid, the Brenner, mixed, and undifferentiated types. Cytoskeleton intermediate filament composition of ovarian tissues indicates that the cytokeratin and vimentin are observed in ovarian surface epithelium along with the common ovarian epithelial tumors. The current study aimed at investigating the cytokeratin and vimentin expression in epithelial ovarian tumors to establish a diagnostic relevance...
2018: Iranian Journal of Pathology
https://www.readbyqxmd.com/read/29724308/-value-of-magnetic-resonance-imaging-texture-feature-analysis-in-the-differential-diagnosis-between-pancreatic-serous-cystadenoma-and-mucinous-cystadenoma
#4
Bo Tao Wang, Lei He, Gang Liu, Meng Qi Liu, Zhi Ye Chen
Objective To investigate the difference of tumor textures presented on T1-weighted image(T1WI) and T2-weighted image(T2WI) between pancreatic serous cystadenoma and mucinous cystadenoma. Methods Subjects including 24 patients with serous cystadenoma and 20 patients with mucinous cystadenoma who were treated in Hainan Branch of Chinese PLA General Hospital were enrolled in this study.The texture analysis was performed on T1WI and T2WI,and the texture parameters included angular second moment,contrast,correlation,inverse difference moment(IDM),and entropy...
April 28, 2018: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29716620/postprandial-increase-in-serum-ca125-as-a-surrogate-biomarker-for-early-diagnosis-of-ovarian-cancer
#5
Zhuowei Gu, Yifeng He, Yue Zhang, Mo Chen, Keqi Song, Yuting Huang, Qing Li, Wen Di
BACKGROUND: CA125 is a prevalently used serum biomarker for detecting ovarian cancer over the last three decades. However, it has a significant deficiency in screening for early-stage cancer. With the purpose of exploring an effective approach to improve its performance in early diagnosis, we investigated the postprandial fluctuation pattern of cancer-derived CA125 and the underlying mechanism. METHODS: In two medical centers, 551 patients sonographically diagnosed with ovarian (adnexal) cysts (< 5 cm in diameter) were enrolled and divided into five disease groups (pelvic inflammatory cysts, retention cysts, endometrioma, benign/borderline cystadenoma and malignant cysts)...
May 1, 2018: Journal of Translational Medicine
https://www.readbyqxmd.com/read/29670799/a-modified-technique-for-laparoscopic-spleen-preserving-distal-pancreatectomy
#6
Andreas Papatriantafyllou, Theodoros Mavromatis, Theano Demestiha, Dimitrios Filippou, Panagiotis Skandalakis
Spleen preserving laparoscopic distal pancreatectomy is considered as first choice operation for symptomatic benign or small malignant lesions located at the body or tail of the pancreas. The two main surgical techniques that have been proposed and widely adopted for spleen preserving laparoscopic distal pancreatectomy are the Warshaw and Kimura techniques. A novel modified approach for laparoscopic spleen preserving distal pancreatectomy is presented. The technique was initially performed in a 57-year-old female patient with mucinous cystadenoma...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/29669190/analysis-of-histologic-follow-up-and-risk-of-malignancy-for-salivary-gland-neoplasm-of-uncertain-malignant-potential-proposed-by-the-milan-system-for-reporting-salivary-gland-cytopathology
#7
Haiyan Liu, Clarissa Ljungren, Fan Lin, Matthew A Zarka, Longwen Chen
BACKGROUND: The Milan System for Reporting Salivary Gland Cytopathology is a tiered classification scheme that includes 6 diagnostic categories. Neoplasm, which is 1 of the 6 proposed categories, consists of benign neoplasm and neoplasm of uncertain malignant potential (NUMP). NUMP is reserved for a salivary gland neoplasm without clear distinction between benign and malignant. The objective of this study was to assess the risk of malignancy (ROM) of NUMP. METHODS: A retrospective analysis was conducted on 656 salivary gland fine-needle aspiration specimens from 2010 to 2016...
April 18, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/29660844/moray-micro-forceps-biopsy-improves-the-diagnosis-of-specific-pancreatic-cysts
#8
M Lisa Zhang, Ronald N Arpin, William R Brugge, David G Forcione, Omer Basar, Martha B Pitman
BACKGROUND: Making a specific diagnosis of pancreatic cysts preoperatively is difficult. The new disposable Moray micro forceps biopsy (MFB) device allows tissue sampling from the pancreatic cyst wall/septum and aims to improve diagnosis. This study compares the diagnostic performance of the MFB with the current conventional analysis of pancreatic cyst fluid (PCF). METHODS: A total of 48 patients sampled with MFB were identified. Cysts were classified as mucinous on PCF based on extracellular mucin/mucinous epithelium, carcinoembryonic antigen (CEA) levels ≥192 ng/mL, or KRAS/GNAS mutation...
April 16, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/29656130/robotic-resection-of-benign-nonadrenal-retroperitoneal-tumors-a-consecutive-case-series
#9
Qu Liu, Yuanxing Gao, Zhiming Zhao, Guodong Zhao, Rong Liu, Wan Yee Lau
BACKGROUND: The deep location, narrow operative space and proximity to major vessels make minimally invasive resection of nonadrenal retroperitoneal tumors (NTRs) challenging and rarely reported. This study aimed to evaluate the safety and feasibility of robotic resection of benign nonadrenal retroperitoneal tumors. METHODS: The demographics and perioperative outcomes of a consecutive series of patients who underwent robotic NTR resection between January 1, 2015, and August 30, 2017, were analyzed...
April 12, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29610616/ovarian-strumal-carcinoid-tumour-case-report
#10
Vesna S Antovska, Milka Trajanova, Iskra Krstevska, Irena Gosheva, Jasmina Chelebieva, Irina Prodanova
BACKGROUND: Ovarian strumal carcinoid is a germ cell tumour characterised by a mixture of thyroid tissue and carcinoid. Ovarian struma is a very rare occurrence with 0.3-1% incidence of all ovarian tumours and 3% of mature teratomas. Primary carcinoid ovarian tumours are still uncommon as a part of mature teratoma or mucinous cystadenoma. There are four major variants of a carcinoid tumour: insular, trabecular, strumal and mucinous. A strumal carcinoid is an unusual form of ovarian teratoma composed of an intimate admixture of thyroid/carcinoid tissues...
March 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29593866/a-rare-case-of-giant-extra-ovarian-mucinous-cystadenoma-arising-from-sigmoid-mesocolon
#11
Andrew Tan, Ran Li, Mohammed Rafique, Sharon Qin, Toan Pham
An 80-year-old female presented with one month history of acutely worsening abdominal distention and pain, without features of bowel obstruction. A giant intra-abdominal simple cyst, separate from the ovaries, was seen on imaging. Initial haematological and biochemical investigations, including tumour markers, were normal. At laparotomy, the cystic tumour was discovered to arise from the sigmoid mesocolon and was resected en bloc . Histopathology revealed the tumour to be a benign extra-ovarian mucinous cystadenoma, which is a neoplasm of ovarian origin that can arise from extra-ovarian sites, including the mesentery...
March 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29581685/incidental-findings-in-routine-histopathological-examination-of-appendectomy-specimens-retrospective-analysis-of-1970-patients
#12
Oğuzhan Dincel, Mustafa Göksu, Bilge Aydın Türk, Burçin Pehlivanoğlu, Serap İşler
Diseases and tumors of the appendix vermiformis are very rare, except for acute appendicitis. This study aimed to examine rare findings in the histopathologic examinations of specimens of patients undergoing appendectomy due to the diagnosis of acute appendicitis. The files of 1970 patients undergoing appendectomy due to the diagnosis of acute appendicitis between March 2012 and March 2016 were retrospectively investigated. Rare findings were found in 59 (3 %) patients, and these were evaluated in detail. Patients' age, gender, pathology reports, and postoperation follow-ups were recorded...
February 2018: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29580358/clinicopathological-features-and-management-of-appendiceal-mucoceles-a-systematic-review
#13
REVIEW
William F Morano, Elizabeth M Gleeson, Sean H Sullivan, Vennila Padmanaban, Beth L Mapow, Patricia A Shewokis, Jesus Esquivel, Wilbur B Bowne
Appendiceal mucoceles (AMs) are rare mucin-containing neoplasms with malignant potential. Lack of evidence-based data exists defining clinicopathological features for management. MEDLINE search between 1995 and 2015 was performed using search criteria "Appendix mucocele." Systematic review of patient-, pathologic-, and treatment-related characteristics was performed and data analyzed. Among 276 cases of non-perforated AMs, 163 (59%) patients were female, with variable and nonspecific presentation...
February 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29521268/pseudomyxoma-peritonei-a-case-report-and-review-of-the-literature
#14
Juan Gómez Rivas, José María Alonso-Dorrego, Diego M Carrión, Mónica Vega Robalino, Pilar González-Peramato
OBJECTIVE: We present the case of a patient incidentally diagnosed with a pelvic mass next to the bladder. After surgical excision, definitive diagnosis was pseudomyxoma peritonei. We provide a concise review of the literature of this pathology. METHODS: A 55 year-old male patient, was found to have, in annual routine ultrasound, a pelvic retrovesical mass. CT guided needle aspirate showed a tumor with myxoid changes and low aggressive cytology. Surgical excision was performed...
March 2018: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29476610/inspissated-cyst-fluid-in-endoscopic-ultrasound-guided-fine-needle-aspiration-of-pancreatic-cysts
#15
Ivan Chebib, Emily Albanese, Aristana Scourtas, Martha B Pitman
BACKGROUND: Inspissated cyst fluid may be identified on pancreatic cyst aspiration cytology. We report on the cytomorphologic characteristics of inspissated cyst fluid on EUS-FNA of pancreatic cysts and correlate this finding with histopathology or multimodal (cytology, cyst fluid analysis, molecular pathology, imaging) classification of cyst type. METHODS: The department archives were searched for pancreatic cyst fine-needle aspiration biopsies that contained dessicated, crystalline or inspissated material on cytologic preparations...
May 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29415811/-simple-mucinous-cyst-of-the-pancreas-case-report-and-literature-review
#16
Maxime Hamon, Pierre Balladur, Jean-François Fléjou
Simple mucinous cyst of the pancreas is an unusual pancreatic cyst, first described by Kosmahl et al. in 2002 with 5 cases. We describe a case of simple mucinous cyst of the pancreas, followed by a literature review. The physiopathology of this cyst is still unclear. It is an epithelial cyst, presenting as unilocular cystic lesion of the pancreatic body or tail, with a clear content, and no communication with the pancreatic duct. Microscopically, the cyst is lined by mucin-producing cells with mild atypia, and contains a fibrous wall without ovarian-like stroma...
April 2018: Annales de Pathologie
https://www.readbyqxmd.com/read/29394168/low-grade-endometrioid-stromal-sarcoma-of-the-paratestis-a-novel-report-with-molecular-confirmation-of-jazf1-suz12-translocation
#17
Abbas Agaimy, Evgeny A Moskalev, Wera Weisser, Thorsten Bach, Florian Haller, Arndt Hartmann
Tumors with Müllerian-like serous or mucinous phenotypes originating in the testis and its adnexa are rare neoplasms that have been increasingly recognized in recent years. Cystadenomas with or without ovarian-type stroma, borderline tumors, and adenocarcinomas are the main documented types. Although a handful cases of putative endometrioid adenocarcinomas have been reported, to our knowledge no case of endometrial stromal-type neoplasm has ever been reported in the literature. A 59-year-old man presented with a 2 cm left intrascrotal mass that was found on sonographic examination to arise from the epididymal tail with prominent vascularization...
May 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29381965/urachal-borderline-mucinous-cystadenoma-a-rare-case-report-and-literature-review
#18
Jingjun Wu, Ailian Liu, Anliang Chen, Pengxin Zhang
RATIONALE: Urachal borderline mucinous cystadenoma is very rare and has only 9 cases in the current literature with the biological behavior between adenoma and adenocarcinoma. PATIENT CONCERNS: We reported a 41-year-old man with moderate lower abdominal pain, and the imaging examination found an irregular cystic lesion extending from umbilicus to the dome of urinary bladder with significant separations and calcifications. DIAGNOSES: The diagnosis was confirmed according to the specific anatomical location and pathological examination which was proved as mucinous cystadenoma with low malignant potential...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29376413/a-case-report-and-a-literature-review-of-primary-retroperitoneal-mucinous-cystadenoma-the-importance-of-imaging-in-diagnosis-and-management
#19
Filippo Pesapane, Sofie Van Renterghem, Francesca Patella, Pieter De Visschere, Geert Villeirs
Primary retroperitoneal mucinous cystadenoma (PRMC) is an extremely rare tumor: its histogenesis and its biological behavior remain speculative. Since most retroperitoneal tumors are malignant, a preoperative diagnosis of benignity is essential and it can be reached through imaging examinations, allowing a conservative management approach. We describe the case of a 52-year-old woman with abdominal pain and a palpable mass. Computed tomography of the abdomen revealed a retroperitoneal cystic mass, which was resected successfully through laparoscopy and diagnosed as PRMC...
January 29, 2018: Future Oncology
https://www.readbyqxmd.com/read/29373116/uncommon-hereditary-gynaecological-tumour-syndromes-pathological-features-in-tumours-that-may-predict-risk-for-a-germline-mutation
#20
REVIEW
Karuna Garg, Anthony N Karnezis, Joseph T Rabban
The most common hereditary gynaecological tumour syndromes are hereditary breast and ovarian cancer syndrome and Lynch syndrome. However, pathologists also may encounter gynaecological tumours in women with rare hereditary syndromes. Many of these tumours exhibit distinctive gross and microscopic features that are associated with a risk for an inherited gene mutation. The sensitivity and specificity of these tumour pathology features for predicting an inherited mutation vary depending on the syndrome. By recognising these tumour features, pathologists may potentially contribute to the diagnosis of an unsuspected syndrome by recommending referral of the patient for formal risk assessment by genetic counselling...
February 2018: Pathology
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