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https://www.readbyqxmd.com/read/27930355/premature-cardiac-aging-in-south-asian-compared-to-afro-caribbean-subjects-in-a-community-based-screening-study
#1
Eduard Shantsila, Alena Shantsila, Paramjit S Gill, Gregory Y H Lip
BACKGROUND: People of South Asian (SAs) and African Caribbean (AC) origin have increased cardiovascular morbidity, but underlying mechanisms are poorly understood. Aging is the key predictor of deterioration in diastolic function, which can be assessed by echocardiography using E/e' ratio as a surrogate of left ventricular (LV) filling pressure. The study aimed to assess a possibility of premature cardiac aging in SA and AC subjects. METHODS AND RESULTS: We studied 4540 subjects: 2880 SA and 1660 AC subjects...
November 10, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27927868/diabetes-and-insulin-therapy-are-associated-with-increased-risk-of-hospitalization-for-infection-but-not-mortality-a-longitudinal-cohort-study
#2
John P Donnelly, Sunil Nair, Russell Griffin, John W Baddley, Monika M Safford, Henry E Wang, Nathan I Shapiro
BACKGROUND: Epidemiologic and experimental evidence suggests that individuals with diabetes are at increased risk of infection. We sought to examine the association of diabetes and insulin therapy with hospitalization for infection and 28-day mortality. METHODS: We performed a prospective cohort study using data from 30,239 community-dwelling participants aged ≥45 years enrolled in the REasons for Geographic and Racial Differences in Stroke (REGARDS) study. We defined diabetes as fasting glucose ≥126 mg/L (or glucose ≥200 mg/L for those not fasting), the use of insulin or oral hypoglycemic agents, or self-reported history...
December 7, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27912203/prognostic-factors-associated-with-15-year-mortality-in-patients-with-hospitalized-systolic-hf-results-of-the-observational-community-based-epical-cohort-study
#3
Nelly Agrinier, Nathalie Thilly, Serge Briançon, Yves Juillière, Paul-Michel Mertes, Jean-Pierre Villemot, François Alla, Faiez Zannad
AIMS: Little data on very long-term survival and associated prognostic factors in heart failure (HF) are available. The aim was to describe 15-year survival and to identify the baseline prognostic factors associated with mortality in a community-based sample of patients hospitalized for systolic HF. METHODS: Vital status was collected 15years after inclusion of 352 patients hospitalized for systolic HF born in France from the prospective cohort EPICAL. The prognostic value of baseline socioeconomic, clinical and biological characteristics on 15-year mortality was assessed using Cox models...
November 12, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27908278/comparison-of-predictors-of-hip-fracture-and-mortality-after-hip-fracture-in-community-dwellers-with-and-without-alzheimer-s-disease-exposure-matched-cohort-study
#4
Anna-Maija Tolppanen, Heidi Taipale, Antti Tanskanen, Jari Tiihonen, Sirpa Hartikainen
BACKGROUND: Dementia, with Alzheimer's disease (AD) being the most common form, is a major hip fracture risk factor, but currently it is not known whether the same factors predict hip fracture among persons with and without dementia/AD. We compared the predictors of hip fracture and mortality after hip fracture in persons with and without AD. METHODS: An exposure-matched cohort of all community-dwellers of Finland who received a new clinically verified AD diagnosis in 2005-2011 and had no history of previous hip fracture (N = 67,072) and an age, sex, and region-matched cohort of persons without AD (N = 67,072)...
December 1, 2016: BMC Geriatrics
https://www.readbyqxmd.com/read/27906998/explaining-the-decline-in-coronary-heart-disease-mortality-in-the-netherlands-between-1997-and-2007
#5
Carla Koopman, Ilonca Vaartjes, Ineke van Dis, W M Monique Verschuren, Peter Engelfriet, Edith M Heintjes, Anneke Blokstra, Dorly J H Deeg, Marjolein Visser, Michiel L Bots, Martin O'Flaherty, Simon Capewell
OBJECTIVE: We set out to determine what proportion of the mortality decline from 1997 to 2007 in coronary heart disease (CHD) in the Netherlands could be attributed to advances in medical treatment and to improvements in population-wide cardiovascular risk factors. METHODS: We used the IMPACT-SEC model. Nationwide information was obtained on changes between 1997 and 2007 in the use of 42 treatments and in cardiovascular risk factor levels in adults, aged 25 or over...
2016: PloS One
https://www.readbyqxmd.com/read/27906837/different-impacts-of-hypertension-and-diabetes-mellitus-on-all-cause-and-cardiovascular-mortality-in-community-dwelling-older-adults-the-rancho-bernardo-study
#6
Jee-Young Oh, Matthew A Allison, Elizabeth Barrett-Connor
OBJECTIVES: Although the prevalence rates of hypertension (HTN) and diabetes mellitus are slowing in some high-income countries, HTN and diabetes mellitus remain as the two major risk factors for atherosclerotic cardiovascular disease (CVD), the leading cause of death in the United States and worldwide. We aimed to observe the association of HTN and diabetes mellitus with all-cause and CVD mortality in older white adults. METHODS: All community-dwelling Rancho Bernardo Study participants who were at least 55 years old and had carefully measured blood pressure and plasma glucose from 75-g oral glucose tolerance test at the baseline visit (1984-1987, n = 2186) were followed up until death or the last clinic visit in 2013 (median 14...
January 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27905939/causes-of-death-in-vanuatu
#7
Karen Carter, Viran Tovu, Jeffrey Tila Langati, Michael Buttsworth, Lester Dingley, Andy Calo, Griffith Harrison, Chalapati Rao, Alan D Lopez, Richard Taylor
BACKGROUND: The population of the Pacific Melanesian country of Vanuatu was 234,000 at the 2009 census. Apart from subsistence activities, economic activity includes tourism and agriculture. Current completeness of vital registration is considered too low to be usable for national statistics; mortality and life expectancy (LE) are derived from indirect demographic estimates from censuses/surveys. Some cause of death (CoD) data are available to provide information on major causes of premature death...
March 15, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27891373/retrospective-comparison-of-clinical-characteristics-and-in-hospital-outcomes-among-diabetic-and-non-diabetic-adults-with-acute-pyelonephritis
#8
Shailesh C Trivedi, Sanjeev R Phatak, Renu S Trivedi
INTRODUCTION: Acute Pyelonephritis (APN) is a common infection in community. Diabetes Mellitus (DM) may have different effect on clinical characteristics and outcomes of APN compared to non-diabetic individuals. AIM: To compare clinical characteristics and assess outcomes of APN patients with and without DM. MATERIALS AND METHODS: A retrospective analysis of 122 patients with DM (n=61) and without DM (n=61) was conducted at a single, private, urban set-up from Gujarat, India...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27888559/ten-year-all-cause-mortality-and-its-association-with-vision-among-indigenous-australians-within-central-australia-the-central-australian-ocular-health-study
#9
Ebony Liu, Soo K Ng, Shyalle Kahawita, Nicholas H Andrew, Tim Henderson, Jamie E Craig, John Landers
BACKGROUND: No studies to date have explored the association of vision with mortality in Indigenous Australians. We aimed to determine the 10-year all-cause mortality and its associations among Indigenous Australians living in central Australia. DESIGN: Prospective observational cohort study PARTICIPANTS: 1257 (93.0%) out of 1347 patients from The Central Australian Ocular Health Study, over the age of 40 years, were available for follow up during a 10-year period...
November 26, 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27887931/revision-of-primary-sleeve-gastrectomy-to-roux-en-y-gastric-bypass-indications-and-outcomes-from-a-high-volume-center
#10
Robert A Casillas, Scott S Um, Jorge L Zelada Getty, Samantha Sachs, Benjamin B Kim
BACKGROUND: Laparoscopic sleeve gastrectomy (SG) has become an accepted primary bariatric operation. Like other bariatric operations, inadequate weight loss and complications have been reported. OBJECTIVES: The aim of this study was to assess the indications and outcomes of revision of SG to laparoscopic Roux-en-Y gastric bypass (RYGB) at a single community hospital. SETTING: Community hospital, United States. METHODS: Retrospective review of a prospectively collected database identifying SG operations done from February 2009 to June 2014...
October 4, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/27886035/developing-a-model-to-estimate-the-probability-of-bacteremia-in-women-with-community-onset-febrile-urinary-tract-infection
#11
Won Sup Oh, Yeon-Sook Kim, Joon Sup Yeom, Hee Kyoung Choi, Yee Gyung Kwak, Jae-Bum Jun, Seong Yeon Park, Jin-Won Chung, Ji-Young Rhee, Baek-Nam Kim
INTRODUCTION: Among patients with urinary tract infection (UTI), bacteremic cases show higher mortality rates than do nonbacteremic cases. Early identification of bacteremic cases is crucial for severity assessment of patients with febrile UTI. This study aimed to identify predictors associated with bacteremia in women with community-onset febrile UTI and to develop a prediction model to estimate the probability of bacteremic cases. METHODOLOGY: This cross-sectional study included women consecutively hospitalized with community-onset febrile UTI at 10 hospitals in Korea...
November 24, 2016: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/27880070/influence-of-premature-mortality-on-the-link-between-type-2-diabetes-and-hip-fracture-the-fremantle-diabetes-study
#12
Emma Hamilton, Wendy A Davis, David G Bruce, Timothy M E Davis
CONTEXT: Most studies of hip fracture complicating diabetes have used selected patients with incomplete data. None has considered the competing risk of death. OBJECTIVE: To determine influence of the competing risk of death on the association between type 2 diabetes and hip fracture. DESIGN: Longitudinal observational study. SETTING: Urban community. PATIENTS: 1,291 participants with type 2 diabetes (mean±SD age 64...
November 23, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27865754/perinatal-nurse-home-visiting-referral-patterns-among-women-with-diabetes-and-hypertension-in-philadelphia
#13
Joan R Bloch, Susan Zupan, Amy E McKeever, Jennifer L Barkin
OBJECTIVE: To examine access to perinatal nurse home visiting services for high-risk pregnant women who have diabetes or hypertension. DESIGN: Secondary data analysis. SETTING: Philadelphia, PA. PARTICIPANTS: Pregnant women who had a live birth during 2012 and those referred to a community-based agency for perinatal nurse home visiting because of their diagnosis of diabetes or hypertension. METHODS: Access to services was measured by examining referral information (dosage, diagnosis, gestational age at time of referral, and insurance type) retrieved from administrative logs of the community-based organization that provides perinatal home visiting to high-risk pregnant women...
November 16, 2016: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/27863979/comparative-prognostic-performance-of-definitions-of-prediabetes-a-prospective-cohort-analysis-of-the-atherosclerosis-risk-in-communities-aric-study
#14
Bethany Warren, James S Pankow, Kunihiro Matsushita, Naresh M Punjabi, Natalie R Daya, Morgan Grams, Mark Woodward, Elizabeth Selvin
BACKGROUND: No consensus on definitions of prediabetes exists among international organisations. Analysis of associations with different definitions and clinical complications can inform the comparative value of different prediabetes definitions. We compared the risk of future outcomes across different prediabetes definitions based on fasting glucose concentration, HbA1c, and 2 h glucose concentration during over two decades of follow-up in the community-based Atherosclerosis Risk in Communities (ARIC) study...
November 15, 2016: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/27862247/association-between-serum-25-oh-d3-and-cardiovascular-morbidity-and-mortality-in-people-with-type%C3%A2-2-diabetes-a-community-based-cohort-study
#15
M Samefors, R Scragg, T Länne, F H Nyström, C J Östgren
AIM: We aimed to explore the association between vitamin D and cardiovascular morbidity and mortality in people with Type 2 diabetes recruited from a community-based study because there is limited and inconsistent research of this group. METHODS: A prospective community-based cohort study among people aged 55-66 years with Type 2 diabetes as part of The Cardiovascular Risk in Type 2 Diabetes - A Prospective Study in Primary Care (CARDIPP). We analysed serum 25-hydroxyvitamin D3 [25(OH)D3 ] at baseline...
November 18, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/27856810/impacts-of-chronic-kidney-disease-and-diabetes-on-cardiovascular-mortality-in-a-general-japanese-population-a-20-year-follow-up-of-the-nippon-data90-study
#16
Aya Hirata, Tomonori Okamura, Daisuke Sugiyama, Kazuyo Kuwabara, Aya Kadota, Akira Fujiyoshi, Katsuyuki Miura, Nagako Okuda, Takayoshi Ohkubo, Akira Okayama, Hirotsugu Ueshima
BACKGROUND: Studies have shown significant associations of chronic kidney disease (CKD) and diabetes mellitus (DM) with cardiovascular disease (CVD) mortality. The impact on the general population is an important public health issue. However, the population attributable fraction (PAF) of CVD because of CKD and/or DM in a general population is uncertain. METHODS: We followed 7229 participants (age: ≥30 years) with no history of CVD in a Japanese community. We divided participants into four categories according to CKD and/or DM and calculated hazard ratios (HRs) of CVD mortality for each category using a Cox proportional hazards model adjusted for age, dyslipidemia, smoking and alcohol consumption...
November 17, 2016: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/27834240/preventable-death-rates-fell-where-communities-expanded-population-health-activities-through-multisector-networks
#17
Glen P Mays, Cezar B Mamaril, Lava R Timsina
The US health system faces mounting pressure to improve population health. Research suggests a need for greater coordination and alignment across the sectors that deliver medical, public health, and social services. This study uses sixteen years of data from a large cohort of US communities to measure the extent and nature of multisector contributions to population health activities and how these contributions affect community mortality rates. The results show that deaths due to cardiovascular disease, diabetes, and influenza decline significantly over time among communities that expand multisector networks supporting population health activities...
November 1, 2016: Health Affairs
https://www.readbyqxmd.com/read/27832070/pleiotropic-associations-of-allelic-variants-in-a-2q22-region-with-risks-of-major-human-diseases-and-mortality
#18
Alexander M Kulminski, Liang He, Irina Culminskaya, Yury Loika, Yelena Kernogitski, Konstantin G Arbeev, Elena Loiko, Liubov Arbeeva, Olivia Bagley, Matt Duan, Arseniy Yashkin, Fang Fang, Mikhail Kovtun, Svetlana V Ukraintseva, Deqing Wu, Anatoliy I Yashin
Gaining insights into genetic predisposition to age-related diseases and lifespan is a challenging task complicated by the elusive role of evolution in these phenotypes. To gain more insights, we combined methods of genome-wide and candidate-gene studies. Genome-wide scan in the Atherosclerosis Risk in Communities (ARIC) Study (N = 9,573) was used to pre-select promising loci. Candidate-gene methods were used to comprehensively analyze associations of novel uncommon variants in Caucasians (minor allele frequency~2...
November 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27821085/incidence-and-risk-factor-prevalence-of-community-acquired-pneumonia-in-adults-in-primary-care-in-spain-neumo-es-risk-project
#19
I Rivero-Calle, J Pardo-Seco, P Aldaz, D A Vargas, E Mascarós, E Redondo, J L Díaz-Maroto, M Linares-Rufo, M J Fierro-Alacio, A Gil, J Molina, D Ocaña, Federico Martinón-Torres
BACKGROUND: Community-acquired pneumonia (CAP) is a major cause of morbidity and mortality in adults even in developed countries. Several lifestyle factors and comorbidities have been linked to an increased risk, although their prevalence has not been well documented in the primary care setting. The aim of this study is to assess the incidence, risk factor and comorbid conditions distribution of CAP in adults in primary care in Spain. METHODS: Retrospective observational study in adults (>18 years-old) with CAP diagnosed and attended at primary care in Spain between 2009 and 2013, using the Computerized Database for Pharmacoepidemiological Studies in Primary Care (BIFAP)...
November 7, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27820656/insulinlike-growth-factor-binding-protein-1-and-ghrelin-predict-health-outcomes-among-older-adults-chs-cohort
#20
Robert C Kaplan, Garrett Strizich, Chino Aneke-Nash, Clara Dominguez-Islas, Petra Bůžková, Howard Strickler, Thomas Rohan, Michael Pollak, Lewis Kuller, Jorge R Kizer, Anne Cappola, Christopher I Li, Bruce M Psaty, Anne Newman
CONTEXT: Multiple diseases may explain the association of the growth hormone / insulinlike growth factor-I (GH/IGF-I) axis with longevity. OBJECTIVE: To relate circulating GH/IGF-I system protein levels with major health events. DESIGN: Cohort study Setting: Four US communities Participants: Adults (n=2268) 65 years and older free of diabetes and cardiovascular disease. MEASUREMENTS: We assessed insulinlike growth factor binding protein-1 (IGFBP-1) and ghrelin in fasting and 2-hour oral glucose tolerance test (OGTT) blood samples, as well as fasting IGF-I and IGFBP-3...
November 7, 2016: Journal of Clinical Endocrinology and Metabolism
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