keyword
MENU ▼
Read by QxMD icon Read
search

POSE Running

keyword
https://www.readbyqxmd.com/read/29334675/effects-of-running-retraining-on-biomechanical-factors-associated-with-lower-limb-injury
#1
Marcus D Dunn, David B Claxton, Graham Fletcher, Jonathan S Wheat, David M Binney
Injury risk is an important concern for runners; however, limited evidence exists regarding changes to injury risk following running style retraining. Biomechanical factors, such as absolute peak free moment, knee abduction impulse, peak foot eversion and foot eversion excursion, have been shown to predict lower limb injury. The aim of this study was to assess the effects of Pose running retraining on biomechanical factors associated with lower limb running injury. Twenty uninjured recreational runners were pair-matched based on their five km run time performance and randomly assigned to control (n = 10) and intervention (three 2-h Pose running retraining sessions) groups (n = 10)...
January 12, 2018: Human Movement Science
https://www.readbyqxmd.com/read/29316514/risk-based-cost-benefit-analysis-for-evaluating-microbial-risk-mitigation-in-a-drinking-water-system
#2
Viktor Bergion, Andreas Lindhe, Ekaterina Sokolova, Lars Rosén
Waterborne outbreaks of gastrointestinal diseases can cause large costs to society. Risk management needs to be holistic and transparent in order to reduce these risks in an effective manner. Microbial risk mitigation measures in a drinking water system were investigated using a novel approach combining probabilistic risk assessment and cost-benefit analysis. Lake Vomb in Sweden was used to exemplify and illustrate the risk-based decision model. Four mitigation alternatives were compared, where the first three alternatives, A1-A3, represented connecting 25, 50 and 75%, respectively, of on-site wastewater treatment systems in the catchment to the municipal wastewater treatment plant...
December 27, 2017: Water Research
https://www.readbyqxmd.com/read/29304509/effect-of-foot-progression-angle-adjustment-on-the-knee-adduction-moment-and-knee-joint-contact-force-in-runners-with-and-without-knee-osteoarthritis
#3
I C D Fong, W S C Li, W K J Tai, T W R Tsang, J H Zhang, T L W Chen, H Baur, P Eichelberger, R T H Cheung
BACKGROUND: Knee adduction moment (KAM) is often used as a surrogate marker of knee contact force (KCF) during walking. Previous studies have reported potential benefits to reduce KAM in patients with knee osteoarthritis (OA) by foot progression angle adjustment. However, KAM is an external moment and it does not consider any muscle contribution to the joint loading, which should pose a greater influence in running than walking. RESEARCH QUESTION: This study used a computational model to compare KAM and KCF between runners with and without knee OA during running...
December 30, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29298301/mapping-of-global-scientific-research-in-comorbidity-and-multimorbidity-a-cross-sectional-analysis
#4
Ferrán Catalá-López, Adolfo Alonso-Arroyo, Matthew J Page, Brian Hutton, Rafael Tabarés-Seisdedos, Rafael Aleixandre-Benavent
BACKGROUND: The management of comorbidity and multimorbidity poses major challenges to health services around the world. Analysis of scientific research in comorbidity and multimorbidity is limited in the biomedical literature. This study aimed to map global scientific research in comorbidity and multimorbidity to understand the maturity and growth of the area during the past decades. METHODS AND FINDINGS: This was a cross-sectional analysis of the Web of Science...
2018: PloS One
https://www.readbyqxmd.com/read/29281002/an-automated-benchmarking-platform-for-mhc-class-ii-binding-prediction-methods
#5
Massimo Andreatta, Thomas Trolle, Zhen Yan, Jason A Greenbaum, Bjoern Peters, Morten Nielsen
Motivation: Computational methods for the prediction of peptide-MHC binding have become an integral and essential component for candidate selection in experimental T cell epitope discovery studies. The sheer amount of published prediction methods - and often discordant reports on their performance - poses a considerable quandary to the experimentalist who needs to choose the best tool for their research. Results: With the goal to provide an unbiased, transparent evaluation of the state-of-the-art in the field, we created an automated platform to benchmark peptide-MHC class II binding prediction tools...
December 21, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29239272/mental-models-of-cause-and-inheritance-for-type-2-diabetes-among-unaffected-individuals-who-have-a-positive-family-history
#6
Sandra Daack-Hirsch, Lisa L Shah, Alyssa D Cady
Using the familial risk perception (FRP) model as a framework, we elicited causal and inheritance explanations for type 2 diabetes (T2D) from people who do not have T2D but have a family history for it. We identified four composite mental models for cause of T2D: (a) purely genetic; (b) purely behavioral/environmental; (c) direct multifactorial, in which risk factors interact and over time directly lead to T2D; and (d) indirect multifactorial, in which risk factors interact and over time cause a precursor health condition (such as obesity or metabolic syndrome) that leads to T2D...
December 1, 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/29214049/latent-autoimmune-diabetes-of-adulthood-case-report
#7
Cristen P Page, Brian Fitzgerald, Emily M Hawes
Background: Primary care clinicians will see a higher incidence of type 2 diabetes in adult patients, and the diagnosis and management of an initial presentation of type 1 diabetes can pose challenges to clinicians who see it less frequently. Symptoms of hyperglycemia and risk of ketoacidosis may be missed. Further, endocrine autoimmune disease can run together in patients and families. Case presentation: A 49-year-old Caucasian female with history of pituitary adenoma and Graves' disease with history of thyroid ablation presented in the outpatient setting due to hand tingling of her right middle finger that was worse in the mornings and improved throughout the day...
2017: Clinical Diabetes and Endocrinology
https://www.readbyqxmd.com/read/29202830/experiences-from-the-anatomy-track-in-the-ontology-alignment-evaluation-initiative
#8
REVIEW
Zlatan Dragisic, Valentina Ivanova, Huanyu Li, Patrick Lambrix
BACKGROUND: One of the longest running tracks in the Ontology Alignment Evaluation Initiative is the Anatomy track which focuses on aligning two anatomy ontologies. The Anatomy track was started in 2005. In 2005 and 2006 the task in this track was to align the Foundational Model of Anatomy and the OpenGalen Anatomy Model. Since 2007 the ontologies used in the track are the Adult Mouse Anatomy and a part of the NCI Thesaurus. Since 2015 the data in the Anatomy track is also used in the Interactive track of the Ontology Alignment Evaluation Initiative...
December 4, 2017: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/29195718/patient-caregiver-and-physician-perspectives-on-participating-in-a-thoracic-rapid-tissue-donation-program
#9
Gwendolyn Quinn, Rebecca D Pentz, Teresita Muñoz-Antonia, Theresa A Boyle, Matthew B Schabath, Christie Pratt, Andrea Shaffer, Luisa Duarte, Meghan Bowman-Curci, Scott Antonia, Alberto Chiappori, Benjamin Creelan, Jhanelle E Gray, Charles Williams, Eric Haura
OBJECTIVE: The collection of posthumous tissue from advanced stage lung cancer patients is beneficial to medical science. Recruiting living patients to a Rapid Tissue Donation Program (RTD) poses several psychosocial challenges and little is known about perceptions of joining this type of program. This study qualitatively examined perceptions of advanced stage lung cancer patients (n=14) participating in a lung cancer RTD program, their NoK (n=11), and physicians (n=6) at the Thoracic Oncology Clinic at H...
November 28, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/29168199/experimental-investigation-of-left-ventricular-flow-patterns-after-percutaneous-edge-to-edge-mitral-valve-repair
#10
Morteza Jeyhani, Shahrokh Shahriari, Michel Labrosse
Mitral valve percutaneous edge-to-edge repair (PEtER) is a viable solution in high-risk patients with severe symptomatic mitral regurgitation. However, the generated double-orifice configuration poses challenges for the evaluation of the hemodynamic performance of the mitral valve and may alter flow patterns in the left ventricle (LV) during diastole. This in vitro study aims to evaluate the hemodynamic modifications following a simulated PEtER. A custom-made mitral valve was developed, and two configurations were tested: (i) a single-orifice valve with mitral regurgitation and (ii) a double-orifice mitral valve configuration following PEtER...
November 23, 2017: Artificial Organs
https://www.readbyqxmd.com/read/29150937/cgmp-production-and-analysis-of-bg505-sosip-664-an-extensively-glycosylated-trimeric-hiv-1-envelope-glycoprotein-vaccine-candidate
#11
Antu K Dey, Albert Cupo, Gabriel Ozorowski, Vaneet K Sharma, Anna-Janina Behrens, Eden P Go, Thomas J Ketas, Anila Yasmeen, Per J Klasse, Eddy Sayeed, Heather Desaire, Max Crispin, Ian A Wilson, Rogier W Sanders, Thomas Hassell, Andrew Ward, John P Moore
We describe the properties of BG505 SOSIP.664 HIV-1 envelope glycoprotein trimers produced under current Good Manufacturing Practice (cGMP) conditions. These proteins are the first of a new generation of native-like trimers that are the basis for many structure-guided immunogen development programs aimed at devising how to induce broadly neutralizing antibodies (bNAbs) to HIV-1 by vaccination. The successful translation of this prototype demonstrates the feasibility of producing similar immunogens on an appropriate scale and of an acceptable quality for Phase I experimental medicine clinical trials...
November 18, 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/29149853/cost-of-delivering-health-care-services-at-primary-health-facilities-in-ghana
#12
Maxwell Ayindenaba Dalaba, Paul Welaga, Chieko Matsubara
BACKGROUND: There is limited knowledge on the cost of delivering health services at primary health care facilities in Ghana which is posing a challenge in resource allocations. This study therefore estimated the cost of providing health care in primary health care facilities such as Health Centres (HCs) and Community-based Health Planning and Services (CHPS) in Ghana. METHODS: The study was cross-sectional and quantitative data was collected from the health provider perspective...
November 17, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29073131/human-action-recognition-based-on-kinematic-similarity-in-real-time
#13
Qingqiang Wu, Guanghua Xu, Longting Chen, Ailing Luo, Sicong Zhang
Human action recognition using 3D pose data has gained a growing interest in the field of computer robotic interfaces and pattern recognition since the availability of hardware to capture human pose. In this paper, we propose a fast, simple, and powerful method of human action recognition based on human kinematic similarity. The key to this method is that the action descriptor consists of joints position, angular velocity and angular acceleration, which can meet the different individual sizes and eliminate the complex normalization...
2017: PloS One
https://www.readbyqxmd.com/read/29040432/machine-learning-accelerates-md-based-binding-pose-prediction-between-ligands-and-proteins
#14
Kei Terayama, Hiroaki Iwata, Mitsugu Araki, Yasushi Okuno, Koji Tsuda
Motivation: Fast and accurate prediction of protein-ligand binding structures is indispensable for structure-based drug design (SBDD) and accurate estimation of binding free energy of drug candidate molecules in drug discovery. Recently, accurate pose prediction methods based on short-MD simulations such as MM-PBSA and MM-GBSA among generated docking poses have been used. Since molecular structures obtained from MD simulation depends on the initial condition, taking the average over different initial conditions leads to better accuracy...
October 11, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29022952/ocular-morbidity-among-porters-at-high-altitudes
#15
Subodh Gnyawali, Gauri Shankar Shrestha, Safal Khanal, Talisa Dennis, John C Spencer
INTRODUCTION: High altitude, often characterized by settings over 2400m, can be detrimental to the human body and pose a significant risk to ocular health. Reports concerning various ocular morbidities occurring as a consequence of high altitude are limited in the current literature. OBJECTIVES: This study was aimed at evaluating the ocular health of porters working at high altitudesof Himalayas in Nepal. MATERIALS AND METHODS: A mobile eye clinic was set up in Ghat and patient data were collected from its out- patient unit by a team of seven optometrists which was run for five days...
January 2017: Nepalese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28963926/hydrostatic-pressure-and-temperature-affect-the-tolerance-of-the-free-living-marine-nematode-halomonhystera-disjuncta-to-acute-copper-exposure
#16
Lisa Mevenkamp, Alastair Brown, Chris Hauton, Anna Kordas, Sven Thatje, Ann Vanreusel
Potential deep-sea mineral extraction poses new challenges for ecotoxicological research since little is known about effects of abiotic conditions present in the deep sea on the toxicity of heavy metals. Due to the difficulty of collecting and maintaining deep-sea organisms alive, a first step would be to understand the effects of high hydrostatic pressure and low temperatures on heavy metal toxicity using shallow-water relatives of deep-sea species. Here, we present the results of acute copper toxicity tests on the free-living shallow-water marine nematode Halomonhystera disjuncta, which has close phylogenetic and ecological links to the bathyal species Halomonhystera hermesi...
September 20, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28947764/on-the-long-run-efficacy-of-punishments-and-recommendations-in-a-laboratory-public-goods-game
#17
Ananish Chaudhuri, Tirnud Paichayontvijit
We use decision-making experiments with human participants to study cooperation in a laboratory public goods game. Such games pose a conflict between cooperating, which is socially optimal and free-riding, which promotes individual self-interest. Prior research emphasizes the need for de-centralized peer-to-peer punishments as an evolutionarily stable response to the problem of free-riding, especially where interactions occur over long horizons. We show that a simple exhortative message appealing to participants' goodwill can achieve high rates of cooperation in social dilemmas played over many rounds, even in the absence of punishments for free-riding...
September 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28913782/docking-of-small-molecules-to-farnesoid-x-receptors-using-autodock-vina-with-the-convex-pl-potential-lessons-learned-from-d3r-grand-challenge-2
#18
Maria Kadukova, Sergei Grudinin
The 2016 D3R Grand Challenge 2 provided an opportunity to test multiple protein-ligand docking protocols on a set of ligands bound to farnesoid X receptor that has many available experimental structures. We participated in the Stage 1 of the Challenge devoted to the docking pose predictions, with the mean RMSD value of our submission poses of 2.9 Å. Here we present a thorough analysis of our docking predictions made with AutoDock Vina and the Convex-PL rescoring potential by reproducing our submission protocol and running a series of additional molecular docking experiments...
September 14, 2017: Journal of Computer-aided Molecular Design
https://www.readbyqxmd.com/read/28902511/exploring-the-stability-of-ligand-binding-modes-to-proteins-by-molecular-dynamics-simulations-a-cross-docking-study
#19
Kai Liu, Hironori Kokubo
Docking has become an indispensable approach in drug discovery research to predict the binding mode of a ligand. One great challenge in docking is to efficiently refine the correct pose from various putative docking poses through scoring functions. We recently examined the stability of self-docking poses under molecular dynamics (MD) simulations and showed that equilibrium MD simulations have some capability to discriminate between correct and decoy poses. Here, we have extended our previous work to cross-docking studies for practical applications...
October 23, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28895578/challenges-in-comprehensive-management-of-spinal-cord-injury-in-india-and-in-the-asian-spinal-cord-network-region-findings-of-a-survey-of-experts-patients-and-consumers
#20
H S Chhabra, S Sharma, M Arora
STUDY DESIGN: Online survey. OBJECTIVES: To understand the prevailing scenario of the comprehensive management of spinal cord injuries (SCI) in India and in the Asian Spinal Cord Network (ASCoN) region, especially with a view to document the challenges faced and its impact. SETTING: Indian Spinal Injuries Centre. METHODS: A questionnaire was designed which covered various aspects of SCI management. Patients, consumers (spinal injured patients discharged since at least 1 year) and experts in SCI management from different parts of India and the ASCoN region were approached to complete the survey...
September 12, 2017: Spinal Cord
keyword
keyword
47422
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"