Ujjwal M Mahajan, Bettina Oehrle, Simon Sirtl, Ahmed Alnatsha, Elisabetta Goni, Ivonne Regel, Georg Beyer, Marlies Vornhülz, Jakob Vielhauer, Ansgar Chromik, Markus Bahra, Fritz Klein, Waldemar Uhl, Tim Fahlbusch, Marius Distler, Jürgen Weitz, Robert Grützmann, Christian Pilarsky, Frank Ulrich Weiss, Gordian Adam, John P Neoptolemos, Holger Kalthoff, Roland Rad, Nicole Christiansen, Bianca Bethan, Beate Kamlage, Markus M Lerch, Julia Mayerle
BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma cancer (PDAC) is a highly lethal malignancy requiring efficient detection when the primary tumor is still resectable. We previously developed the MxPancreasScore comprising 9 analytes and serum carbohydrate antigen 19-9 (CA19-9), achieving an accuracy of 90.6%. The necessity for 5 different analytical platforms and multiple analytical runs, however, hindered clinical applicability. We therefore aimed to develop a simpler single-analytical run, single-platform diagnostic signature...
July 21, 2022: Gastroenterology