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https://www.readbyqxmd.com/read/28073355/factors-associated-with-improvement-or-decline-in-cognitive-function-after-an-ischemic-stroke-in-korea-the-korean-stroke-cohort-for-functioning-and-rehabilitation-kosco-study
#1
Jin A Yoon, Deog Young Kim, Min Kyun Sohn, Jongmin Lee, Sam-Gyu Lee, Yang-Soo Lee, Eun Young Han, Min Cheol Joo, Gyung-Jae Oh, Junhee Han, Minsu Park, Kyung Pil Park, Kyung-Ha Noh, Won Hyuk Chang, Yong-Il Shin, Yun-Hee Kim
BACKGROUND: We conducted a prospective cohort study to investigate prevalence of poststroke cognitive impairment at 3 and 12 months after stroke onset and identify clinical and demographic factors associated with improvement or decline in cognitive function between 3 months and 12 months. METHODS: We analyzed the cognitive assessments of total patients and patients older than 65 years separately. All patients with an ischemic stroke were divided into normal cognitive group (NCG) and impaired cognition group (ICG) by using a cutoff score on the Korean Mini-Mental State Examination (K-MMSE)...
January 10, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28072724/fatal-antiphospholipid-syndrome-following-endoscopic-transnasal-transsphenoidal-surgery-for-a-pituitary-tumor-a-case-report
#2
Chiao-Zhu Li, Chiao-Ching Li, Chih-Chuan Hsieh, Meng-Chi Lin, Dueng-Yuan Hueng, Feng-Chen Liu, Yuan-Hao Chen
INTRODUCTION: The fatal type of antiphospholipid syndrome is a rare but life-threating condition. It may be triggered by surgery or infection. Endoscopic transnasal-transsphenoidal surgery is a common procedure for pituitary tumor. We report a catastrophic case of a young woman died of fatal antiphospholipid syndrome following endoscopic transnasal-transsphenoidal surgery. METHODS AND RESULT: A 31-year-old woman of a history of stroke received endoscopic transnasal-transsphenoidal surgery for a pituitary tumor...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28067964/cardiovascular-consequences-of-binge-drinking-an-integrative-review-with-implications-for-advocacy-policy-and-research
#3
Mariann R Piano, Adriana Mazzuco, Minkyung Kang, Shane A Phillips
Worldwide, binge drinking is a major public health problem. The popularized health risks associated with binge drinking include physical injury and motor vehicle crashes; less attention has been given to the negative effects on the cardiovascular (CV) system. The primary aims of this review were to provide a summary of the adverse effects of binge drinking on the risk and development of CV disease and to review potential pathophysiologic mechanisms. Using specific inclusion criteria, an integrative review was conducted that included data from human experimental, prospective cross-sectional, and cohort epidemiological studies that examined the association between binge drinking and CV conditions such as hypertension, myocardial infarction, stroke, and arrhythmias...
January 9, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28067185/effect-of-formal-education-on-vascular-cognitive-impairment-after-stroke-a-meta-analysis-and-study-in-young-stroke-patients
#4
Roy P C Kessels, Willem Sake Eikelboom, Pauline Schaapsmeerders, Noortje A M Maaijwee, Renate M Arntz, Ewoud J van Dijk, Frank-Erik de Leeuw
OBJECTIVES: The extent of vascular cognitive impairment (VCI) after stroke varies greatly across individuals, even when the same amount of brain damage is present. Education level is a potentially protective factor explaining these differences, but results on its effects on VCI are inconclusive. METHODS: First, we performed a meta-analysis on formal education and VCI, identifying 21 studies (N=7770). Second, we examined the effect of formal education on VCI in young-stroke patients who were cognitively assessed on average 11...
January 9, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28066141/dehydroevodiamine%C3%A2-hcl-enhances-cognitive-function-in-memory-impaired-rat-models
#5
Ki Young Shin, Ka Young Kim, Yoo-Hun Suh
Progressive memory impairment such as that associated with depression, stroke, and Alzheimer's disease (AD) can interfere with daily life. In particular, AD, which is a progressive neurodegenerative disorder, prominently features a memory and learning impairment that is related to changes in acetylcholine and abnormal β-amyloid (Aβ) deposition in the brain. In the present study, we investigated the effects of dehydroevodiamine·HCl (DHED) on cognitive improvement and the related mechanism in memory-impaired rat models, namely, a scopolamine-induced amnesia model and a Aβ1-42-infused model...
January 2017: Korean Journal of Physiology & Pharmacology
https://www.readbyqxmd.com/read/28064210/characteristics-of-autoantibodies-targeting-14-3-3-proteins-and-their-association-with-clinical-features-in-newly-diagnosed-giant-cell-arteritis
#6
Anne Kistner, Marc B Bigler, Kathrin Glatz, Simon B Egli, Fabian S Baldin, Florian A Marquardsen, Matthias Mehling, Katharina M Rentsch, Daniel Staub, Markus Aschwanden, Mike Recher, Thomas Daikeler, Christoph T Berger
OBJECTIVES: Autoantibodies are useful biomarkers for diagnosing and monitoring treatment in some autoimmune diseases. Antibodies against isoforms of 14-3-3 protein have been proposed as biomarkers for the presence of aortic aneurysm in large-vessel vasculitis (LVV). Here, we aimed to evaluate the diagnostic role and potential immunopathological involvement of anti-14-3-3 antibodies in newly diagnosed LVV patients. METHODS: Antibodies against three isoforms of 14-3-3 (γ, ε and ζ) were measured in 90 subjects: 48 GCA and 3 Takayasu's arteritis (TA) patients, and 39 controls (non-inflammatory and inflammatory diseases), using a multiplexed bead-based immunoassay and immunoprecipitation studies...
January 7, 2017: Rheumatology
https://www.readbyqxmd.com/read/28062999/relationship-between-increased-carotid-artery-stiffness-and-idiopathic-subjective-tinnitus
#7
C Bayraktar, S Taşolar
Tinnitus is defined as perception of sound with no external stimulus, and can separate into pulsatile and non-pulsatile types. Arterial stiffness is a parameter that can predict the cardiovascular event and associated with incidence of stroke. It has been shown that increased arterial stiffness may lead to microvascular damage in brain. Our aim was to assess the arterial stiffness of the carotid system in the development and severity of idiopathic subjective tinnitus. Forty subjective tinnitus patients and 40 age- and sex-matched controls were enrolled in the study...
January 6, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28062255/differential-effects-of-bihemispheric-and-unihemispheric-transcranial-direct-current-stimulation-in-young-and-elderly-adults-in-verbal-learning
#8
Valentina Fiori, Michael Nitsche, Luigi Iasevoli, Gabriella Cucuzza, Carlo Caltagirone, Paola Marangolo
For the past few years, the potential of transcranial direct current stimulation (tDCS) for the treatment of several pathologies has been investigated. In the language domain, several studies, in healthy and brain-damaged populations, have already shown that tDCS is effective in enhancing naming, repetition and semantic word generation. In those studies, different tDCS electrode configurations have been tested, however, a direct comparison between different montages in verbal learning has never been conducted...
January 3, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28060916/nocturia-is-associated-with-slipping-and-falling
#9
So Young Kim, Woojin Bang, Min-Su Kim, Bumjung Park, Jin-Hwan Kim, Hyo Geun Choi
Several reports have demonstrated associations between falls and nocturia in the elderly. However, little information is available regarding other age groups. This study evaluated the relationship between the frequency of nocturia and falls in men using a large, population-based survey in Korea, and the results were adjusted for various confounding factors. Data from a 2011 Korean community health survey (KCHS) were retrieved for 92,660 men aged 19 to 103 years. Information regarding the history of slips or falls in the past year was collected...
2017: PloS One
https://www.readbyqxmd.com/read/28053539/complex-neurological-symptoms-in-bilateral-thalamic-stroke-due-to-percheron-artery-occlusion
#10
Paola Caruso, Paolo Manganotti, Rita Moretti
The artery of Percheron is a rare anatomical variant where a single thalamic perforating artery arises from the proximal posterior cerebral artery (P1 segment) between the basilar artery and the posterior communicating artery and supplies the rostral mesencephalon and both paramedian territories of the thalami. Almost one-third of human brains present this variant. Occlusion of the artery of Percheron mostly results in a bilateral medial thalamic infarction, which usually manifests with altered consciousness (including coma), vertical gaze paresis, and cognitive disturbance...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/28052941/congenital-anomaly-of-the-posterior-arch-of-the-atlas-a-rare-risk-factor-for-posterior-circulation-stroke
#11
Zhi-Yuan Ouyang, Min-Jian Qiu, Zhe Zhao, Xiao-Bing Wu, Lu-Sha Tong
We report an extremely rare case involving a posterior arch anomaly of the atlas, causing a vertebral artery dissection (VAD) induced posterior circulation stroke. A 16-year-old girl was admitted to hospital because of new onset dizziness. VAD related multiple infarction in the posterior circulation was revealed. The congenital posterior arch anomaly of the atlas, along with instability of the atlantoaxial joint, were discovered accidentally during follow-up. This is the first case of ischemic stroke related to atlantal posterior arch aplasia and atlantoaxial instability...
January 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28052272/ischemic-stroke-in-young-adults-of-northern-china-characteristics-and-risk-factors-for-recurrence
#12
Fang Li, Li Yang, Rui Yang, Wei Xu, Fu-Ping Chen, Nan Li, Jin-Biao Zhang
BACKGROUND: Young adults accounted for 10-14% of ischemic stroke patients. The risk factors may differ in this population from elder patients. In addition, the factors associated with stroke recurrence in this population have not been well investigated. OBJECTIVE: The study aimed to investigate the characteristics and risk factors associated with recurrence of ischemic stroke in young adults. METHODS: Clinical data of 1,395 patients of age 18-45 years who were treated between 2008 and 2014 in 3 centers located in northern China was reviewed...
January 5, 2017: European Neurology
https://www.readbyqxmd.com/read/28049200/a-mouse-model-of-post-stroke-pneumonia-induced-by-intra-tracheal-inoculation-with-streptococcus-pneumoniae
#13
Eva Mracsko, Sabine Stegemann-Koniszewski, Shin-Young Na, Alexander Dalpke, Dunja Bruder, Felix Lasitschka, Roland Veltkamp
BACKGROUND: Stroke-induced immunodeficiency increases the risk of infectious complications, which adversely affects neurological outcome. Among those, pneumonia affects as many as one third of stroke patients and is the main contributor to mortality in the post-acute phase of stroke. Experimental findings on post-stroke susceptibility to spontaneous pneumonia in mice are contradictory. Here, we established a mouse model inducing standardized bacterial pneumonia and characterized the impaired pulmonary cellular and humoral immune responses after experimental stroke...
January 4, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28045864/bilateral-central-retinal-vein-occlusions-in-a-young-patient-with-a-history-of-eosinophilic-pneumonia-and-thalamic-stroke
#14
Gina Yu, Peng Sun, Tavé van Zyl, Rachel Tandias, Jorge G Arroyo
PURPOSE: To describe a case of a central retinal vein occlusion in a young patient with a history of eosinophilic pneumonia. METHODS: A retrospective case report of a 45-year-old woman with acute painless vision loss for 9 days after multiple episodes of eosinophilic pneumonia and thalamic stroke. Fluorescein angiography, spectral domain optical coherence tomography, and clinical examination were performed. She was then treated with intravitreal bevacizumab and pan-retinal photocoagulations...
December 29, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28044315/the-electric-field-distributions-in-anatomical-head-models-during-transcranial-direct-current-stimulation-for-post-stroke-rehabilitation
#15
Zoi Manoli, Marta Parazzini, Paolo Ravazzani, Theodoros Samaras
PURPOSE: The lack of knowledge of the electric field distribution inside the brain of stroke patients receiving transcranial direct current stimulation (tDCS) calls for estimating it computationally. Moreover, the impact on this distribution of a novel clinical management approach which involves secondary motor areas (SMA) in stroke rehabilitation needs to be evaluated. Finally, the differences in the electric field distributions due to gender and age need to be investigated. METHODS: This work presents the development of two different anatomical models (young adult female and elderly male) with an ischemic stroke region of spherical volume 10 cm(3) or 50 cm(3) , using numerical models of the Virtual Population (ViP)...
November 21, 2016: Medical Physics
https://www.readbyqxmd.com/read/28042220/internal-carotid-artery-fibromuscular-dysplasia-in-a-child-incidental-postmortem-finding-after-head-injury
#16
Arulselvi Subramanian, Garima Aggarwal, Deepak Agarwal, Sanjeev Lalwani
Fibromuscular dysplasia (FMD) is a rare, segmental, nonatheromatous, and noninflammatory arterial disease of unknown etiology. It predominantly involves renal artery (60-75%) followed by extracranial part of the internal carotid artery and vertebral arteries (25-30%). The disease typically affects middle-aged women and involves intermediate-sized arteries throughout the body. There are rare case reports of extracranial FMD compounding a trauma case. A patient was brought to trauma center emergency with a history of fall from height...
January 2017: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/28041798/early-seizures-predict-the-development-of-epilepsy-in-children-and-adolescents-with-stroke
#17
Ina Breitweg, Celina von Stülpnagel, Tom Pieper, Karen Lidzba, Hans Holthausen, Martin Staudt, Gerhard Kluger
PURPOSE: To identify risk factors for the development of epilepsy after pediatric stroke. METHODS: Retrospective analysis of hospital charts of 93 children and adolescents with post-neonatal non-traumatic stroke and a minimum follow-up of two years. Seizures during the first 48 h after onset of stroke symptoms were defined as "early seizures"; when two or more seizures occurred after this period, the patient was classified as "epileptic". RESULTS: Early seizures, young age at stroke and MRI evidence of cortical involvement were observed more frequently in the children who developed epilepsy...
December 18, 2016: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28030894/hypercoagulability-and-mortality-of-patients-with-stroke-and-active-cancer-the-oasis-cancer-study
#18
Mi Ji Lee, Jong-Won Chung, Myung-Ju Ahn, Seonwoo Kim, Jin Myoung Seok, Hye Min Jang, Gyeong-Moon Kim, Chin-Sang Chung, Kwang Ho Lee, Oh Young Bang
Background and Purpose: Patients with active cancer are at an increased risk for stroke. Hypercoagulability plays an important role in cancer-related stroke. We aimed to test whether 1) hypercoagulability is a predictor of survival, and 2) correction of the hypercoagulable state leads to better survival in patients with stroke and active cancer. Methods: We recruited consecutive patients with acute ischemic stroke and active systemic cancer between January 2006 and July 2015...
December 12, 2016: Journal of Stroke
https://www.readbyqxmd.com/read/28030891/impact-of-slow-blood-filling-via-collaterals-on-infarct-growth-comparison-of-mismatch-and-collateral-status
#19
Jeong Pyo Son, Mi Ji Lee, Suk Jae Kim, Jong-Won Chung, Jihoon Cha, Gyeong-Moon Kim, Chin-Sang Chung, Kwang Ho Lee, Oh Young Bang
Background and Purpose: Perfusion-diffusion mismatch has been evaluated to determine whether the presence of a target mismatch helps to identify patients who respond favorably to recanalization therapies. We compared the impact on infarct growth of collateral status and the presence of a penumbra, using magnetic resonance perfusion (MRP) techniques. Methods: Consecutive patients who were candidates for recanalization therapy and underwent serial diffusion-weighted imaging (DWI) and MRP were enrolled...
December 12, 2016: Journal of Stroke
https://www.readbyqxmd.com/read/28028147/cannabis-tobacco-alcohol-use-and-the-risk-of-early-stroke-a-population-based-cohort-study-of-45-000-swedish-men
#20
Daniel Falkstedt, Valerie Wolff, Peter Allebeck, Tomas Hemmingsson, Anna-Karin Danielsson
BACKGROUND AND PURPOSE: Current knowledge on cannabis use in relation to stroke is based almost exclusively on clinical reports. By using a population-based cohort, we aimed to find out whether there was an association between cannabis use and early-onset stroke, when accounting for the use of tobacco and alcohol. METHODS: The cohort comprises 49 321 Swedish men, born between 1949 and 1951, who were conscripted into compulsory military service between the ages of 18 and 20...
December 27, 2016: Stroke; a Journal of Cerebral Circulation
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