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https://www.readbyqxmd.com/read/28295470/preconception-tsh-levels-and-pregnancy-outcomes-a-population-based-cohort-study-in-184-611-women
#1
Shi Chen, Xiang Zhou, Huijuan Zhu, Hongbo Yang, Fengying Gong, Linjie Wang, Man Zhang, Yu Jiang, Chengsheng Yan, Jianqiang Li, Qing Wang, Shikun Zhang, Hui Pan
BACKGROUND: Whether subclinical hypothyroidism adversely impacts pregnancy outcomes is inconclusive, and limited data are available on the optimal TSH range in women planning pregnancy. OBJECTIVE: To investigate the association between maternal preconception TSH levels and pregnancy outcomes. DESIGN: Population-based cohort study. METHODS: From 2010 to 2012, the free National Pre-pregnancy Checkups Project recruited 248,501 pairs of volunteer couples across China, of which 184,611women, who subsequently became pregnant, were studied...
March 15, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28292826/arrhythmia-risk-and-%C3%AE-blocker-therapy-in-pregnant-women-with-long-qt-syndrome
#2
Kohei Ishibashi, Takeshi Aiba, Chizuko Kamiya, Aya Miyazaki, Heima Sakaguchi, Mitsuru Wada, Ikutaro Nakajima, Koji Miyamoto, Hideo Okamura, Takashi Noda, Toshifumi Yamauchi, Hideki Itoh, Seiko Ohno, Hideki Motomura, Yoshiharu Ogawa, Hiroko Goto, Takaomi Minami, Nobue Yagihara, Hiroshi Watanabe, Kanae Hasegawa, Akihiro Terasawa, Hitoshi Mikami, Kayo Ogino, Yukiko Nakano, Sato Imashiro, Yosuke Fukushima, Yoshimitsu Tsuzuki, Koko Asakura, Jun Yoshimatsu, Isao Shiraishi, Shiro Kamakura, Yoshihiro Miyamoto, Satoshi Yasuda, Takashi Akasaka, Minoru Horie, Wataru Shimizu, Kengo Kusano
BACKGROUND: Pregnancy is one of the biggest concerns for women with long QT syndrome (LQTS). OBJECTIVES: This study investigated pregnancy-related arrhythmic risk and the efficacy and safety of β-blocker therapy for lethal ventricular arrhythmias in pregnant women with LQTS (LQT-P) and their babies. METHODS: 136 pregnancies in 76 LQT-P (29±5 years old; 22 LQT1, 36 LQT2, one LQT3, and 17 genotype-unknown) were enrolled. We retrospectively analysed their clinical and electrophysiological characteristics and pregnancy outcomes in the presence (BB group: n=42) or absence of β-blocker therapy (non-BB group: n=94)...
March 14, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28289463/antenatal-characteristics-of-roma-female-population-in-virovitica-podravina-county-croatia
#3
Jadranko Šegregur, Domagoj Šegregur
INTRODUCTION: This study reports about antenatal characteristics of Roma minority population. The study was designed to investigate data about health behaviours known to be associated with reproductive outcomes of Roma women that have very good living conditions and relatively high resource availability. METHODS: A retrospective study included 204 Roma and 408 non-Roma hospitalised singleton births that occurred in the Maternity Ward of the General Hospital Virovitica in the period from 1991 to 2010...
March 1, 2017: Zdravstveno Varstvo
https://www.readbyqxmd.com/read/28288649/medical-termination-of-pregnancy-in-general-practice-in-australia-a-descriptive-interpretive-qualitative-study
#4
Angela J Dawson, Rachel Nicolls, Deborah Bateson, Anna Doab, Jane Estoesta, Ann Brassil, Elizabeth A Sullivan
BACKGROUND: Australian Government approval in 2012 for the use of mifepristone and misoprostol for medical termination of pregnancy (MTOP) allows general practitioners (GPs) to provide early gestation abortion in primary care settings. However, uptake of the MTOP provision by GPs appears to be low and the reasons for this have been unclear. This study investigated the provision of and referral for MTOP by GPs. METHODS: We undertook descriptive-interpretive qualitative research and selected participants for diversity using a matrix...
March 14, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28282529/evidence-of-socio-economic-stress-and-female-foeticide-in-racial-disparities-in-the-gender-ratio-at-birth-in-the-united-states-1995-2014
#5
Victor Grech
BACKGROUND: Males are born in excess of females, expressed as M/T (male/total births), which is expected to approximate 0.515. Racial M/T disparities have been long known. This study was carried out in order to identify such disparities in different races in the United States. DESIGN: Monthly male and female live births by race for the entire US were obtained from the website of the Centers for Disease Control and Prevention for 1995-2014 for the four racial groups: American Indian or Alaska Native, Asian or Pacific Islander, Black or African American and White...
March 1, 2017: Early Human Development
https://www.readbyqxmd.com/read/28277599/pregnancy-complications-after-hysteroscopic-metroplasty-a-ten-year-case-control-study
#6
Alessandro Loddo, Maurizio Nicola D'Alterio, Manuela Neri, Francesca Masala, Fiorenza Lo Cane, Gian Benedetto Melis
INTRODUCTION: Septate uterus is one of the most common congenital uterine anomalies and it may effect female reproductive health causing different obstetric complications, in particular miscarriages and reduction of fertility. MATERIALS AND METHODS: We conducted a retrospective case-control (1:4) comparative study (Canadian Task Force Classification II-2) with the purpose to evaluate pregnancy complications (abnormal fetal presentations, preterm deliveries, and caesarean sections) and reproductive outcome after hysteroscopic metroplasty...
March 9, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28258586/pre-implantation-genetic-screening-among-women-experiencing-recurrent-failure-of-in-vitro-fertilization
#7
Safak Hatirnaz, Alev Ozer, Ebru Hatirnaz, Melahat Atasever, Serdar Başaranoglu, Mine Kanat-Pektas, Murat Api
OBJECTIVE: To determine the efficiency of pre-implantation genetic screening (PGS) among women scheduled to undergo intracytoplasmic sperm injection who had experienced recurrent in vitro fertilization (IVF) failure. METHODS: The present retrospective cohort study reviewed the medical records of consecutive women who had experienced recurrent IVF failure and had presented at a private IVF facility in Trabzon Province, Turkey, to undergo intracytoplasmic sperm injection between May 1, 2012, and December 31, 2014...
March 3, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28256367/impact-of-systemic-lupus-erythematosus-on-maternal-and-fetal-outcomes-following-pregnancy-a-meta-analysis-of-studies-published-between-years-2001-2016
#8
REVIEW
Pravesh Kumar Bundhun, Mohammad Zafooruddin Sani Soogund, Feng Huang
BACKGROUND: Previous research has already shown systemic lupus erythematosus (SLE) to have severe consequences on pregnancy outcomes. However, insufficient number of participants, which were mainly limited to one particular region, limited outcomes analyzed and lack of evidence based analysis to support systematic reviews of the literature were the limitations observed. Therefore, by improving these limitations, we aimed to systematically show the impact of SLE on maternal and fetal outcomes following pregnancy...
February 27, 2017: Journal of Autoimmunity
https://www.readbyqxmd.com/read/28256306/clinical-follow-up-of-pregnancy-in-myasthenia-gravis-patients
#9
Renata D Ducci, Paulo J Lorenzoni, Claudia S K Kay, Lineu C Werneck, Rosana H Scola
This study aimed to analyze the outcome and impact of pregnancy in women with myasthenia gravis (MG). Obstetric and clinical data were retrospectively analyzed before, during and after pregnancy. Predictors of outcome were studied. We included 35 pregnancies from 21 MG patients. In the course of MG symptoms in 30 pregnancies with live births, 50% deteriorated (mainly during the second trimester, p = 0.028), 30% improved, and 20% remained unchanged. The deterioration group had more frequent abnormal repetitive nerve stimulation (RNS) (p = 0...
February 1, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28255768/different-routes-of-misoprostol-for-cervical-priming-in-first-trimester-surgical-abortions-a-randomized-blind-trial
#10
Hadas Ganer Herman, Ram Kerner, Ohad Gluck, Hagit Feit, Ran Keidar, Jacob Bar, Ron Sagiv
PURPOSE: To compare effectiveness and patient satisfaction of different routes of misoprostol for short-term (same day) cervical priming in first trimester surgical abortions. METHODS: In a blind randomized trial, patients undergoing surgical abortion at a gestational age of 6 + 0-14 + 6 were administered oral, vaginal, or sub-lingual 400 mcg misoprostol, 1.5 to 4 h prior to procedure. Surgeons blinded to patient allocation evaluated cervical priming. The primary outcome was initial cervical dilatation...
March 3, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28254231/transcervical-double-balloon-catheter-as-an-alternative-and-salvage-method-for-medical-termination-of-pregnancy-in-midtrimester
#11
Yi-An Tu, Chih-Ling Chen, Yen-Ling Lai, Shin-Yu Lin, Chien-Nan Lee
OBJECTIVE: Termination of pregnancy in midtrimester can be performed surgically or medically. The aim of this study was to evaluate the medical methods, and the additional efficacy of using a transcervical double-balloon catheter in midtrimester termination. MATERIALS AND METHODS: In this retrospective study, we included 167 pregnant women admitted during the period from January 1, 2011, to June 31, 2015, who were between 14 weeks and 28 weeks of gestation, and underwent intended termination of pregnancy at our center...
February 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28209547/pregnancy-after-urinary-diversion-at-young-ages-risks-and-outcome
#12
Nina Huck, S Schweizerhof, P Honeck, A Neisius, J W Thüroff, R Stein
OBJECTIVE: To assess the urologic and obstetric outcomes during and after pregnancy following urinary diversion (UD) performed during childhood or adolescence. MATERIALS AND METHODS: From our UD database, we identified 25 women who became pregnant between 1981 and 2013. Reasons for UD were neurogenic bladder, exstrophy, trauma, sinus urogenitalis, and interstitial cystitis. Seventeen had continent cutaneous diversion, 4 had continent anal diversion, and 4 had colonic conduit...
February 14, 2017: Urology
https://www.readbyqxmd.com/read/28176511/prevalence-of-illicit-drug-use-at-the-end-of-pregnancy-a-cross-sectional-study-at-the-time-of-birth
#13
Amadeu Roca Comas, Joan S Vila Domènech, Joana Massa Solé, Patricia Timoneda Paz, Mar Peñas Boira, Francisco J Herrero Espinet, Josep Sánchez Jiménez, Anna Ballester Martínez
BACKGROUND: Drug use during pregnancy is associated with adverse perinatal outcomes. This study was conducted to assess the prevalence of consumption of drugs of abuse in pregnant women at the end of gestation. METHODS: Cross-sectional study of all consecutive pregnant women in labor admitted to a regional hospital in Calella (Barcelona, Spain) in labor over one year period (2014- 2015). Women who gave written consent to take part in the study provided a urine sample on admission and completed a questionnaire with toxic habits-related questions...
February 7, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28170398/emergency-obstetric-care-in-a-rural-district-of-burundi-what-are-the-surgical-needs
#14
E De Plecker, R Zachariah, A M V Kumar, M Trelles, S Caluwaerts, W van den Boogaard, J Manirampa, K Tayler-Smith, M Manzi, K Nanan-N'zeth, B Duchenne, B Ndelema, W Etienne, P Alders, R Veerman, R Van den Bergh
OBJECTIVES: In a rural district hospital in Burundi offering Emergency Obstetric care-(EmOC), we assessed the a) characteristics of women at risk of, or with an obstetric complication and their types b) the number and type of obstetric surgical procedures and anaesthesia performed c) human resource cadres who performed surgery and anaesthesia and d) hospital exit outcomes. METHODS: A retrospective analysis of EmOC data (2011 and 2012). RESULTS: A total of 6084 women were referred for EmOC of whom 2534(42%) underwent a major surgical procedure while 1345(22%) required a minor procedure (36% women did not require any surgical procedure)...
2017: PloS One
https://www.readbyqxmd.com/read/28161494/impact-of-uterine-scar-on-pain-experienced-during-outpatient-hysteroscopy-a-prospective-blinded-comparative-study
#15
Amr H Wahba, AbdelGany M Hassan, Mohamed Kotb, Hossam ElShenoufy, Hisham M Haggag
STUDY OBJECTIVE: To study the impact of uterine scar on pain experienced during outpatient hysteroscopy. DESIGN: A prospective blinded comparative study DESIGN: classification: (Canadian Task Force Classification II-1) SETTING: Outpatient hysteroscopy clinic at a University Hospital PATIENTS: We included 140 women in the childbearing period attending outpatient hysteroscopy clinic. Patients were divided into two groups; Group A included patients with previous uterine scar (n=70) and Group B included those with unscarred uterus (n =70)...
February 1, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28156197/risk-factors-for-perinatal-mortality-in-murmansk-county-russia-a-registry-based-study
#16
Anna A Usynina, Andrej M Grjibovski, Alexandra Krettek, Jon Øyvind Odland, Alexander V Kudryavtsev, Erik Eik Anda
BACKGROUND: Factors contributing to perinatal mortality (PM) in Northwest Russia remain unclear. This study investigated possible associations between selected maternal and fetal characteristics and PM based on data from the population-based Murmansk County Birth Registry. OBJECTIVE: This study investigated possible associations between selected maternal and fetal characteristics and PM based on data from the population-based Murmansk County Birth Registry. METHODS: The study population consisted of all live- and stillbirths registered in the Murmansk County Birth Registry during 2006-2011 (n = 52,806)...
2017: Global Health Action
https://www.readbyqxmd.com/read/28150393/acquired-hemophilia-a-manifesting-as-plasma-transfusion-uncontrolled-severe-bleeding-2-weeks-after-chorioamnionitis-induced-abortion
#17
Ayumi Matsuoka, Hiromasa Sasaki, Chiharu Sugimori, Shinya Hirabuki, Tsutomu Hoshiba, Hiroshi Fujiwara
Acquired hemophilia A (AHA) is a serious and rare complication of pregnancy, caused by autoantibodies to coagulation factor VIII after delivery. We here report the case of a 36-year-old primigravida woman who developed AHA following chorioamnionitis-caused miscarriage in the second trimester. Thirteen days after abortion, sudden, massive vaginal bleeding occurred with marked prolongation of activated partial thromboplastin time (APTT) in the absence of other abnormal coagulation data. Sequential transfusion of fresh frozen plasma did not achieve normalization of APTT...
February 2, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28143615/coxsackievirus-b4-vertical-transmission-in-a-murine-model
#18
Hela Jaïdane, Aymen Halouani, Habib Jmii, Firas Elmastour, Moncef Mokni, Mahjoub Aouni
BACKGROUND: Life-threatening infections with type B Coxsackieviruses (CV-B) are frequently encountered among newborns and are partly attributed to vertically-transmitted virus. Our current study investigates this alternative way of contamination by CV-B, using a mouse model. METHODS: Pregnant Swiss mice were intraperitoneally inoculated with CV-B4 E2 at gestational day 10(G) or 17G. Dams and offspring were monitored for mortality and morbidity, and sampled at different time-points to document the infection and explore eventual vertical transmission...
January 31, 2017: Virology Journal
https://www.readbyqxmd.com/read/28123251/nonpalpable-intrauterine-device-threads-is-it-a-cause-for-worry
#19
S K Kathpalia, M K Singh, D S Grewal
BACKGROUND: Intrauterine contraceptive device is a popular and effective method of contraception. It can be inserted either as an interval procedure or after abortion or delivery. Threads are attached to the vertical limb so that the user can find out the location of the device. Sometimes the threads are not palpable by the user; this study was conducted to find out the reasons for inability to palpate the threads. METHODS AND RESULTS: The retrospective study was conducted over a period of eight years; 110 female patients who complained of inability to feel the threads were included in the study...
January 2017: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28111453/noninvasive-prenatal-diagnosis-significance-of-erg-methylation-as-a-biomarker-in-down-s-syndrome
#20
Xiangju Liu, Ming Xue
BACKGROUND Down's syndrome (DS) is a genetic disease with chromosome abnormality due to the increasing chromosome 21. This study focused on the clinical application value of ERG methylation level in blood of pregnant women as a biomarker in Down's syndrome. MATERIAL AND METHODS The sham group consisted of 210 nonpregnant women, the positive control group consisted of 33 women with a delivery history of DS fetus, and the negative control group consisted of 60 women with eutocia history. A combination of restriction enzyme digestion experiment and PCR was performed to examine ERG methylation levels, methylation sites, and distribution in blood of pregnant women and in chorion tissues from abortion samples...
January 23, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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