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https://www.readbyqxmd.com/read/28449278/seroepidemiology-and-molecular-characterization-of-hepatitis-e-virus-infection-in-swine-and-occupationally-exposed-workers-in-punjab-india
#1
M Bansal, S Kaur, D Deka, R Singh, J P S Gill
Hepatitis E virus (HEV) has two discrete epidemiological patterns: waterborne epidemics in developing countries only, caused by HEV genotype I, and sporadic zoonotic outbreaks in developing and developed countries caused by genotypes III and IV. This study was designed to investigate seroprevalence, molecular detection and the characterization of HEV by nested RT-PCR in swine as well as the occupational risk to exposed human population in Punjab state of north-western India. The occupational risk-exposed group comprised of swine farmers (organized - mixed feed feeders and unorganized - swill feeders), slaughterhouse workers, sewage workers and veterinary internes...
April 27, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28447193/ebola-and-marburg-virus-vaccines
#2
REVIEW
Pierce Reynolds, Andrea Marzi
The filoviruses, Ebola virus (EBOV), and Marburg virus (MARV), are among the most pathogenic viruses known to man and the causative agents of viral hemorrhagic fever outbreaks in Africa with case fatality rates of up to 90%. Nearly 30,000 infections were observed in the latest EBOV epidemic in West Africa; previous outbreaks were much smaller, typically only affecting less than a few hundred people. Compared to other diseases such as AIDS or Malaria with millions of cases annually, filovirus hemorrhagic fever (FHF) is one of the neglected infectious diseases...
April 26, 2017: Virus Genes
https://www.readbyqxmd.com/read/28446173/impact-of-the-ebola-outbreak-on-routine-immunization-in-western-area-sierra-leone-a-field-survey-from-an-ebola-epidemic-area
#3
Xiaojin Sun, T T Samba, Jianyi Yao, Wenwu Yin, Lin Xiao, Fuqiang Liu, Xiaoqiang Liu, Jikun Zhou, Zengqiang Kou, Hongwei Fan, Hao Zhang, Aqnes Williams, Paul M Lansana, Zundong Yin
BACKGROUND: Since March 2014, the Ebola Virus Disease (EVD) outbreak in West Africa disrupted health care systems - especially in Guinea, Liberia and Sierra Leone - with a consequential stress on the area's routine immunization programs. To address perceived decreased vaccination coverage, Sierra Leone conducted a catch-up vaccination campaign during 24-27 April 2015. We conducted a vaccination coverage survey and report coverage estimates surrounding the time of the EVD outbreak and the catch-up campaign...
April 26, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28445543/comparative-genomic-analysis-between-corynebacterium-pseudotuberculosis-strains-isolated-from-buffalo
#4
Marcus Vinicius Canário Viana, Henrique Figueiredo, Rommel Ramos, Luis Carlos Guimarães, Felipe Luiz Pereira, Fernanda Alves Dorella, Salah Abdel Karim Selim, Mohammad Salaheldean, Artur Silva, Alice R Wattam, Vasco Azevedo
Corynebacterium pseudotuberculosis is a Gram-positive, pleomorphic, facultative intracellular pathogen that causes Oedematous Skin Disease (OSD) in buffalo. To better understand the pathogenic mechanisms of OSD, we performed a comparative genomic analysis of 11 strains of C. pseudotuberculosis isolated from different buffalo found to be infected in Egypt during an outbreak that occurred in 2008. Sixteen previously described pathogenicity islands (PiCp) were present in all of the new buffalo strains, but one of them, PiCp12, had an insertion that contained both a corynephage and a diphtheria toxin gene, both of which may play a role in the adaptation of C...
2017: PloS One
https://www.readbyqxmd.com/read/28445537/predicting-epidemic-evolution-on-contact-networks-from-partial-observations
#5
Jacopo Bindi, Alfredo Braunstein, Luca Dall'Asta
The massive employment of computational models in network epidemiology calls for the development of improved inference methods for epidemic forecast. For simple compartment models, such as the Susceptible-Infected-Recovered model, Belief Propagation was proved to be a reliable and efficient method to identify the origin of an observed epidemics. Here we show that the same method can be applied to predict the future evolution of an epidemic outbreak from partial observations at the early stage of the dynamics...
2017: PloS One
https://www.readbyqxmd.com/read/28444452/ebola-virus-disease-in-children-during-the-2014-2015-epidemic-in-guinea-a-nationwide-cohort-study
#6
Mahamoud Sama Chérif, Nut Koonrungsesomboon, Diénaba Kassé, Sékou Ditinn Cissé, Saliou Bella Diallo, Fatoumata Chérif, Facély Camara, Alpha Koné, Eleonor Fundan Avenido, Mandiou Diakité, Mamadou Pathé Diallo, Edouard Le Gall, Mohamed Cissé, Juntra Karbwang, Kenji Hirayama
The most recent epidemic of Ebola virus disease (EVD) has resulted in more than 11,000 deaths in West Africa. It has threatened child health in the affected countries, including Guinea. This nationwide retrospective cohort study included all children under 20 years of age with laboratory-confirmed EVD in Guinea during the 2014-2015 Ebola outbreak for analysis. Of 8,448 children with probable or suspected EVD, 695 cases were laboratory-confirmed EVD. The overall case fatality rate (CFR) was 62.9%. Pediatric patients with younger age had a significantly higher rate of death (adjusted OR = 0...
April 25, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28443987/seroprevalence-of-bactericidal-antibodies-against-serogroup-b-and-c-meningococci-in-a-university-hospital
#7
C A C Gioia, A P S Lemos, M C O Gorla, R Mendoza-Sassi, B S Figueredo, T Ballester, A Von Groll, B Wedig, N V Ethur, L Bragança, P E A Silva, L G Milagres
Meningococcus serogroup B (MenB), clonal complex 32 (cc 32), was the Brazilian epidemic strain of meningococcal disease (MD) in the 1990's. Currently, meningococcus serogroup C (MenC), cc 103, is responsible for most of the cases of the disease in Brazil. The aim of this study was to investigate the seroprevalence of bactericidal antibody (SBA) against representative epidemic strains of MenC, (N753/00 strain, C:23:P1.22,14-6, cc103) and MenB, (Cu385/83 strain, B:4,7:P1.15,19, cc32) in students and employees of a university hospital in the State of Rio Grande do Sul (RS, Brazil)...
April 20, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28442754/vector-competence-and-transovarial-transmission-of-two-aedes-aegypti-strains-to-zika-virus
#8
Chun-Xiao Li, Xiao-Xia Guo, Yong-Qiang Deng, Dan Xing, Ai-Juan Sun, Qin-Mei Liu, Qun Wu, Yan-de Dong, Ying-Mei Zhang, Heng-Duan Zhang, Wu-Chun Cao, Cheng-Feng Qin, Tong-Yan Zhao
Zika virus (ZIKV) has become a serious threat to global health since the outbreak in Brazil in 2015. Additional Chinese cases have continuously been reported since the first case of laboratory-confirmed ZIKV infection in China on 6 February 2016. Aedes aegypti is the most important vector for ZIKV. This study shows that two strains from China exhibit high levels of midgut infection and highly disseminated infection of salivary glands and ovaries. Both strains can transmit ZIKV to infant mice bitten by infectious mosquitoes...
April 26, 2017: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/28442113/temporal-patterns-of-dengue-epidemics-the-case-of-recent-outbreaks-in-kaohsiung
#9
Mattia Sanna, Ying-Hen Hsieh
OBJECTIVE: To investigate whether major dengue outbreaks in the last two decades in Kaohsiung follow a precise temporal pattern. METHODS: Government daily lab-confirmed dengue case data from three major dengue outbreaks occurring during the last two decades in Kaohsiung in 2002, 2014 and 2015, is utilized to compute the corresponding weekly cumulative percentage of total case numbers. We divide each of the three time series data into two periods to examine the corresponding weekly cumulative percentages of case numbers for each period...
March 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28442104/zika-virus-infection-and-its-emerging-trends-in-southeast-asia
#10
REVIEW
Ahmad Ruzain Salehuddin, Haszianaliza Haslan, Norshalizah Mamikutty, Nurul Hannim Zaidun, Mohamad Fairuz Azmi, Mohamad Mu'izuddin Senin, Syed Baharom Syed Ahmad Fuad, Zar Chi Thent
Zika virus is a mosquito-borne flavivirus that represents a public health emergency at the ongoing epidemic. Previously, this rare virus was limited to sporadic cases in Africa and Asia until its emergence in Brazil, South America in 2015, where it rapidly spread throughout the world. Recently, a high number of cases were reported in Singapore and other Southeast Asia countries. A combination of factors explains the current Zika virus outbreak although it is highly likely that the changes in the climate and high frequency of travelling contribute to the spread of Aedes vector carrying the Zika virus mainly to the tropical climate countries such as the Southeast Asia...
March 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28440550/political-drivers-of-epidemic-response-foreign-healthcare-workers-and-the-2014-ebola-outbreak
#11
Daniel Nohrstedt, Erik Baekkeskov
This study demonstrates that countries responded quite differently to calls for healthcare workers (HCWs) during the Ebola epidemic in West Africa in 2014. Using a new dataset on the scale and timing of national pledges and the deployment of HCWs to states experiencing outbreaks of the virus disease (principally, Guinea, Liberia, and Sierra Leone), it shows that few foreign nations deployed HCWs early, some made pledges but then fulfilled them slowly, and most sent no HCWs at all. To aid understanding of such national responses, the paper reviews five theoretical perspectives that offer potentially competing or complementary explanations of foreign government medical assistance for international public health emergencies...
April 25, 2017: Disasters
https://www.readbyqxmd.com/read/28439448/spatial-determinants-of-ebola-virus-disease-risk-for-the-west-african-epidemic
#12
Kate Zinszer, Kathryn Morrison, Aman Verma, John S Brownstein
INTRODUCTION: Although many studies have investigated the probability of Ebola virus disease (EVD) outbreaks while other studies have simulated the size and speed of EVD outbreaks, few have investigated the environmental and population-level predictors of Ebola transmission once an outbreak is underway. Identifying strong predictors of transmission could help guide and target limited public health resources during an EVD outbreak. We examined several environmental and population-level demographic predictors of EVD risk from the West African epidemic...
March 31, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28435821/utilization-of-pfge-as-a-powerful-discriminative-tool-for-the-investigation-of-genetic-diversity-among-mrsa-strains
#13
Solmaz Ohadian Moghadam, Mohammad Reza Pourmand, Masoumeh Douraghi, Samira Sabzi, Parisa Ghaffari
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is a significant challenge to the burn patient. The implementation of proper monitoring programs and prompt identification of epidemic MRSA strains are critical to consequently control and eradicate potential outbreaks. This study aimed to define the genetic relatedness of MRSA strains isolated from burn patients by analyzing the large fragments of DNA. METHODS: In this cross-sectional study, 126 pus/wound swabs from skin and soft tissue infections (SSTIs) were collected from inpatients of Shahid Motahari Burn Center (Tehran, Iran) in 2013...
March 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28434408/secure-internet-of-things-based-cloud-framework-to-control-zika-virus-outbreak
#14
Sanjay Sareen, Sandeep K Sood, Sunil Kumar Gupta
OBJECTIVES: Zika virus (ZikaV) is currently one of the most important emerging viruses in the world which has caused outbreaks and epidemics and has also been associated with severe clinical manifestations and congenital malformations. Traditional approaches to combat the ZikaV outbreak are not effective for detection and control. The aim of this study is to propose a cloud-based system to prevent and control the spread of Zika virus disease using integration of mobile phones and Internet of Things (IoT)...
April 24, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28431862/application-of-the-cdc-ebolaresponse-modeling-tool-to-disease-predictions
#15
Robert H Gaffey, Cécile Viboud
Model-based predictions were critical in eliciting a vigorous international public health response to the 2014 Ebola Virus Disease outbreak in West Africa. Here, we describe the performances of an extension of the CDC-initiated EbolaResponse Modeling tool to the Ebola Forecasting Challenge, which offered a controlled environment for epidemiological predictions. In the EbolaResponse tool, transmission risks and proportions of population affected by interventions were fitted to data via least square fitting. Prediction performances were evaluated for 5 prediction time points of 4 synthetic outbreaks...
March 10, 2017: Epidemics
https://www.readbyqxmd.com/read/28430561/association-of-gii-p16-gii-2-recombinant-norovirus-strain-with-increased-norovirus-outbreaks-guangdong-china-2016
#16
Jing Lu, Ling Fang, Limei Sun, Hanri Zeng, Yanling Li, Huanying Zheng, Siwei Wu, Feng Yang, Tie Song, Jinyan Lin, Changwen Ke, Yonghui Zhang, Jan Vinjé, Hui Li
An unusual prevalence of recombinant GII.2 noroviruses (GII.P16-GII.2) in Guangdong, China, at the end of 2016 caused a sharp increase in outbreaks of acute gastroenteritis. This event was another non-GII.4 epidemic that emerged after the GII.17 viruses in 2014 and 2015 and warrants global surveillance.
July 15, 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28430168/classical-swine-fever-an-updated-review
#17
REVIEW
Sandra Blome, Christoph Staubach, Julia Henke, Jolene Carlson, Martin Beer
Classical swine fever (CSF) remains one of the most important transboundary viral diseases of swine worldwide. The causative agent is CSF virus, a small, enveloped RNA virus of the genus Pestivirus. Based on partial sequences, three genotypes can be distinguished that do not, however, directly correlate with virulence. Depending on both virus and host factors, a wide range of clinical syndromes can be observed and thus, laboratory confirmation is mandatory. To this means, both direct and indirect methods are utilized with an increasing degree of commercialization...
April 21, 2017: Viruses
https://www.readbyqxmd.com/read/28428164/zika-in-twitter-temporal-variations-of-locations-actors-and-concepts
#18
Anthony Stefanidis, Emily Vraga, Georgios Lamprianidis, Jacek Radzikowski, Paul L Delamater, Kathryn H Jacobsen, Dieter Pfoser, Arie Croitoru, Andrew Crooks
BACKGROUND: The recent Zika outbreak witnessed the disease evolving from a regional health concern to a global epidemic. During this process, different communities across the globe became involved in Twitter, discussing the disease and key issues associated with it. This paper presents a study of this discussion in Twitter, at the nexus of location, actors, and concepts. OBJECTIVE: Our objective in this study was to demonstrate the significance of 3 types of events: location related, actor related, and concept related, for understanding how a public health emergency of international concern plays out in social media, and Twitter in particular...
April 20, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28426311/the-zika-virus-outbreak-in-brazil-knowledge-gaps-and-challenges-for-risk-reduction
#19
Claudia Garcia Serpa Osorio-de-Castro, Elaine Silva Miranda, Carlos Machado de Freitas, Kenneth Rochel de Camargo, Hilarie Hartel Cranmer
We analyzed uncertainties and complexities of the Zika virus outbreak in Brazil, and we discuss risk reduction for future emergencies. We present the public health situation in Brazil and concurrent determinants of the epidemic and the knowledge gaps that persist despite building evidence from research, making public health decisions difficult. Brazil has adopted active measures, but producing desired outcomes may be uncertain because of partial or unavailable information. Reducing population group vulnerabilities and acting on environmental issues are medium- to long-term measures...
April 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28424664/spotted-fever-epidemiology-and-vector-rickettsia-host-relationship-in-rio-de-janeiro-state
#20
Diego C Montenegro, Karla Bitencourth, Stefan V de Oliveira, Ana P Borsoi, Karen M Cardoso, Maria S B Sousa, Cristina Giordano-Dias, Marinete Amorim, Nicolau M Serra-Freire, Gilberto S Gazêta, Reginaldo P Brazil
The eco-epidemiological scenario of spotted fever (SF), a tick-borne disease that affects humans and other animals in several countries around the world, was analyzed in Rio de Janeiro (RJ) State, Brazil. During the last 34 years, 990 SF cases were reported in RJ (the Brazilian state with the highest population density), including 116 cases confirmed by serology (RIFI) or PCR, among 42.39% of the municipalities with reported cases of SF. The epidemiologic dynamics of SF in RJ State are very heterogeneous in time and space, with outbreaks, high mortality rates and periods of epidemiological silence (no SF cases reported)...
2017: Frontiers in Microbiology
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