keyword
https://read.qxmd.com/read/38641958/awareness-and-knowledge-of-chikungunya-virus-infection-among-healthcare-workers-in-hulu-langat-district
#1
JOURNAL ARTICLE
Ummi Ainaa Selamat, Noran Naqiah Hairi, Zailiza Suli
As Chikungunya virus (CHIKV) infection continues to rise globally, including in Malaysia, it is essential for healthcare workers (HCWs) to have adequate knowledge about the disease for diagnostic accuracy and to improve public health surveillance systems. This study aimed to assess awareness and measure the level of knowledge of CHIKV infection among HCWs in the Hulu Langat district and explore associated sociodemographic and skill-related factors. This was a cross-sectional study in which the questionnaire was physically distributed to participants using the universal sampling method...
April 20, 2024: Asia-Pacific Journal of Public Health
https://read.qxmd.com/read/38637499/the-role-of-cxcl2-mediated-crosstalk-between-tumor-cells-and-macrophages-in-fusobacterium-nucleatum-promoted-oral-squamous-cell-carcinoma-progression
#2
JOURNAL ARTICLE
Fujiao Nie, Jie Zhang, Haoyang Tian, Jingjing Zhao, Pizhang Gong, Huiru Wang, Suli Wang, Pishan Yang, Chengzhe Yang
Dysbiosis of the oral microbiota is related to chronic inflammation and carcinogenesis. Fusobacterium nucleatum (Fn), a significant component of the oral microbiota, can perturb the immune system and form an inflammatory microenvironment for promoting the occurrence and progression of oral squamous cell carcinoma (OSCC). However, the underlying mechanisms remain elusive. Here, we investigated the impacts of Fn on OSCC cells and the crosstalk between OSCC cells and macrophages. 16 s rDNA sequencing and fluorescence in situ hybridization verified that Fn was notably enriched in clinical OSCC tissues compared to paracancerous tissues...
April 18, 2024: Cell Death & Disease
https://read.qxmd.com/read/38633039/optimization-of-cofe-2-o-4-nanoparticles-and-graphite-fillers-to-endow-thermoplastic-polyurethane-nanocomposites-with-superior-electromagnetic-interference-shielding-performance
#3
JOURNAL ARTICLE
Anju, Milan Masař, Michal Machovský, Michal Urbánek, Pavol Šuly, Barbora Hanulíková, Jarmila Vilčáková, Ivo Kuřitka, Raghvendra Singh Yadav
The rapid growth, integration, and miniaturization of electronics have raised significant concerns about how to handle issues with electromagnetic interference (EMI), which has increased demand for the creation of EMI shielding materials. In order to effectively shield against electromagnetic interference (EMI), this study developed a variety of thermoplastic polyurethane (TPU)-based nanocomposites in conjunction with CoFe2 O4 nanoparticles and graphite. The filler percentage and nanocomposite thickness were tuned and optimized...
April 16, 2024: Nanoscale advances
https://read.qxmd.com/read/38632992/heterochronic-shift-in-gene-expression-leads-to-ontogenetic-morphological-divergence-between-two-closely-related-polyploid-species
#4
JOURNAL ARTICLE
Peter C Searle, Dennis K Shiozawa, R Paul Evans, Jonathon T Hill, Arminda Suli, Michael R Stark, Mark C Belk
Heterochrony-alteration to the rate or timing of development-is an important mechanism of trait differentiation associated with speciation. Heterochrony may explain the morphological divergence between two polyploid species, June sucker ( Chasmistes liorus ) and Utah sucker ( Catostomus ardens ). The larvae of both species have terminal mouths; however, as adults, June sucker and Utah sucker develop subterminal and ventral mouths, respectively. We document a difference in the timing of shape development and a corresponding change in the timing of gene expression, suggesting the distinctive mouth morphology in June suckers may result from paedomorphosis...
April 19, 2024: IScience
https://read.qxmd.com/read/38627206/sex-dependent-responses-to-high-concentration-of-binge-ethanol-in-spleen-of-adolescent-f344-rats
#5
JOURNAL ARTICLE
Xiangqian Liu, Wenfei Huang, Muhammed Bishir, Colin Hodgkinson, David Goldman, Sulie L Chang
BACKGROUND: We previously reported that binge ethanol induces atrophy of the spleen, a key immune organ, in adolescent male F344 rats. Because there are significant sex effects in immune function, we investigated whether binge ethanol exerts sex-dependent effects on the spleen, including producing splenic atrophy. METHODS: We gave F344 rats ethanol (4.8 g/kg/day; 52% w/v; i.g.) on postnatal days [PND] 36 ~ 38 and sacrificed them on PND 39 for spleen collection...
April 16, 2024: Alcohol Clin Exp Res (Hoboken)
https://read.qxmd.com/read/38599381/tfe3-slc36a1-axis-promotes-resistance-to-glucose-starvation-in-kidney-cancer-cells
#6
JOURNAL ARTICLE
Suli Lv, Zongbiao Zhang, Zhenyong Li, Qian Ke, Xianyun Ma, Neng Li, Xuefeng Zhao, Qingli Zou, Lidong Sun, Tanjing Song
Higher demand for nutrients including glucose is characteristic of cancer. "Starving cancer" has been pursued to curb tumor progression. An ,intriguing regime is to inhibit glucose transporter GLUT1 in cancer cells. In addition, during cancer progression, cancer cells may suffer from insufficient glucose supply. Yet cancer cells can somehow tolerate glucose starvation. Uncovering the underlying mechanisms shall not only shed insight into cancer progression but also benefit cancer therapy. TFE3 is a transcription factor known to activate autophagic genes...
April 8, 2024: Journal of Biological Chemistry
https://read.qxmd.com/read/38576394/effect-of-covid-19-on-routine-immunization-during-health-outreach-in-western-province-papua-new-guinea
#7
JOURNAL ARTICLE
Mikaela Seymour, Maggy Mase, Maria Rumints, Nalisa Neuendorf, Jamee Newland, Niko Wuatai, Mathias Bauri, Lucy Morris, Suli Ilumi, Pamela Toliman, Angela Kelly-Hanku
No abstract text is available yet for this article.
April 5, 2024: Asia-Pacific Journal of Public Health
https://read.qxmd.com/read/38574647/effects-of-multiple-metals-exposure-on-abnormal-liver-function-the-mediating-role-of-low-density-lipoprotein-cholesterol
#8
JOURNAL ARTICLE
Xu Han, Ziquan Lv, Mei'an He, Jinquan Cheng, Yanwei Zhang, Tian Wang, Jiaxin Chen, Yuewei Liu, Dongsheng Hu, Xuli Wu, Rihong Zhai, Hui Huang, Suli Huang
Equilibration of metal metabolism is critical for normal liver function. Most epidemiological studies have only concentrated on the influence of limited metals. However, the single and synergistic impact of multiple-metal exposures on abnormal liver function (ALF) are still unknown. A cross-sectional study involving 1493 Chinese adults residing in Shenzhen was conducted. Plasma concentrations of 13 metals, including essential metals (calcium, copper, cobalt, iron, magnesium, manganese, molybdenum, zinc, and selenium) and toxic metals (aluminum, cadmium, arsenic, and thallium) were detected by the inductively coupled plasma spectrometry (ICP-MS)...
April 3, 2024: Ecotoxicology and Environmental Safety
https://read.qxmd.com/read/38572560/universal-germline-genetic-testing-in-patients-with-hematologic-malignancies-using-dna-isolated-from-nail-clippings
#9
JOURNAL ARTICLE
Ozge Ceyhan-Birsoy, Elise Fiala, Satshil Rana, Margaret Sheehan, Jennifer Kennedy, Zarina Yelskaya, Vikas Rai, Yirong Li, Ciyu Yang, Donna Wong, Ivelise Rijo, Jacklyn Casanova, Joshua Somar, Nikita Mehta, Hyeonjin Park, Silvana Ostafi, Kanika Arora, Angelika Padunan, Mark D Ewalt, Umut Aypar, Panieh Terraf, Maksym Misyura, Sofia Haque, Gerald G Behr, Tamanna Haque, Maria Sulis, Mark B Geyer, Christopher Forlenza, Meghan C Thompson, Maria Carlo, Alicia Latham, Ying Liu, Ahmet Zehir, Rose Brannon, Michael Berger, Luis A Diaz, Ahmet Dogan, Marc Ladanyi, Kseniya Petrova-Drus, Khedoudja Nafa, Kenneth Offit, Maria Arcila, Zsofia K Stadler, Michael F Walsh, Diana Mandelker
Not available.
April 4, 2024: Haematologica
https://read.qxmd.com/read/38569175/postpandemic-sentinel-surveillance-of-respiratory-diseases-in-the-context-of-the-world-health-organization-mosaic-framework-protocol-for-a-development-and-evaluation-study-involving-the-english-primary-care-network-2023-2024
#10
JOURNAL ARTICLE
Xinchun Gu, Conall Watson, Utkarsh Agrawal, Heather Whitaker, William H Elson, Sneha Anand, Ray Borrow, Anna Buckingham, Elizabeth Button, Lottie Curtis, Dominic Dunn, Alex J Elliot, Filipa Ferreira, Rosalind Goudie, Uy Hoang, Katja Hoschler, Gavin Jamie, Debasish Kar, Beatrix Kele, Meredith Leston, Ezra Linley, Jack Macartney, Gemma L Marsden, Cecilia Okusi, Omid Parvizi, Catherine Quinot, Praveen Sebastianpillai, Vanashree Sexton, Gillian Smith, Timea Suli, Nicholas P B Thomas, Catherine Thompson, Daniel Todkill, Rashmi Wimalaratna, Matthew Inada-Kim, Nick Andrews, Victoria Tzortziou-Brown, Rachel Byford, Maria Zambon, Jamie Lopez-Bernal, Simon de Lusignan
BACKGROUND: Prepandemic sentinel surveillance focused on improved management of winter pressures, with influenza-like illness (ILI) being the key clinical indicator. The World Health Organization (WHO) global standards for influenza surveillance include monitoring acute respiratory infection (ARI) and ILI. The WHO's mosaic framework recommends that the surveillance strategies of countries include the virological monitoring of respiratory viruses with pandemic potential such as influenza...
April 3, 2024: JMIR Public Health and Surveillance
https://read.qxmd.com/read/38562176/case-report-anesthetic-management-for-removal-of-tumor-thrombus-in-the-inferior-vena-cava-and-pulmonary-artery-in-renal-cell-carcinoma
#11
Suli Chen, Liangyuan Lu, Xiangli Zheng, Yanjun Lin, Liming Bao, Bao Zhang, Zhanmin Yang
Anesthetic management of patients with renal cell carcinoma with tumor thrombus in the inferior vena cava (IVC) is challenging. This paper reports the experience of anesthesia management in a patient with advanced renal cell carcinoma with thrombus accumulation in the IVC, right atrium, and pulmonary artery who underwent radical nephrectomy and tumor thrombus removal assisted by cardiopulmonary bypass. The emboli, measuring approximately 3 × 6 cm in the left inferior pulmonary artery and 4 × 13 cm in the right main pulmonary artery, were removed completely...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38559437/seroepidemiological-survey-to-cell-culture-rabies-vaccines-ccrv-in-brazil
#12
JOURNAL ARTICLE
Rodrigo Iais da Silva, Luciana Botelho Chaves, Sandriana Dos Ramos Silva, Iana Suly Santos Katz, Elaine Raniero Fernandes, Rene Cunha Neto, Carlos Roberto Padovani, Jose Rafael Modolo, Ricardo J Soares Magalhaes, Holly Crompton, Cassiano Victoria
Rabies is a contagious viral disease that can be easily transmitted by the saliva and brain/nervous system tissues of the infected animals, causing severe and fatal encephalitis in both animals and humans. Vaccination campaigns are crucial to combat and prevent rabies's spread in dogs and humans. The Modified Fuenzalida & Palicios vaccines have been widely used since the 70s and have proven effective in producing a solid serological response. Since 2008, the Brazilian Ministry of Health has introduced a Cell Culture Rabies Vaccine (CCRV) for all dog mass vaccination campaigns in Brazil...
June 2024: One Health
https://read.qxmd.com/read/38554837/microalgal-bacterial-consortia-for-the-treatment-of-livestock-wastewater-removal-of-pollutants-interaction-mechanisms-influencing-factors-and-prospects-for-application
#13
REVIEW
KhinKhin Phyu, Suli Zhi, Junfeng Liang, Chein-Chi Chang, Jiahua Liu, Yuang Cao, Han Wang, Keqiang Zhang
The livestock sector is responsible for a significant amount of wastewater globally. The microalgal-bacterial consortium (MBC) treatment has gained increasing attention as it is able to eliminate pollutants to yield value-added microalgal products. This review offers a critical discussion of the source of pollutants from livestock wastewater and the environmental impact of these pollutants. It also discusses the interactions between microalgae and bacteria in treatment systems and natural habitats in detail...
March 28, 2024: Environmental Pollution
https://read.qxmd.com/read/38553251/network-meta-analysis-of-the-molecular-mechanisms-and-signaling-pathways-underlying-alcohol-induced-thymic-atrophy
#14
JOURNAL ARTICLE
Tatiana Rengifo, Muhammed Bishir, Wenfei Huang, Marylynn Snyder, Sulie L Chang
BACKGROUND: Thymic atrophy is characterized by loss of thymocytes, destruction of thymic architecture, and a subsequent decrease in naïve T cells with compromised immunity. Thymic atrophy occurs during aging. Environmental factors including alcohol misuse also induce thymic atrophy. Despite the link between alcohol misuse and thymic atrophy, the underlying mechanism is understudied. We aimed to identify molecules and signaling pathways that underly alcohol-induced thymic atrophy during aging...
March 29, 2024: Alcohol Clin Exp Res (Hoboken)
https://read.qxmd.com/read/38518150/application-of-thermal-cycling-amplification-chip-method-in-the-detection-of-respiratory-machine-associated-pneumonia-pathogens
#15
JOURNAL ARTICLE
Jiajia Liu, Shuai Zhao, Haiyang Yan, Suli Jin, Jingna Sun, Lidan Xing, Xiaoye Liu, Lisha Wang, Jing Chen
OBJECTIVE: Investigating the application effectiveness of using loop-mediated isothermal amplification (LAMP) on a microfluidic chip to detect the pathogens associated with ventilator-associated pneumonia (VAP). METHODS: Eighty samples of bronchoalveolar lavage fluid from patients with ventilator-associated pneumonia (VAP) were collected at The First Hospital of Hebei Medical University from July 2022 to July 2023. The bacterial culture technique and the LAMP method were used to detect the nucleic acid of the pathogens in the patient samples...
March 22, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38493581/cxcl1-cxcr2-axis-mediates-inflammatory-response-after-sciatic-nerve-injury-by-regulating-macrophage-infiltration
#16
JOURNAL ARTICLE
Suli Jiang, Wei Li, Meiying Song, Jie Liang, Guixian Liu, Qiaochu Du, Luoyang Wang, Haining Meng, Lei Tang, Yanyan Yang, Bei Zhang
Macrophages play a crucial role in the inflammatory response following sciatic nerve injury. Studies have demonstrated that C-X-C motif chemokine (CXCL) 1 recruit macrophages by binding to C-X-C chemokine receptor (CXCR) 2 and participates in the inflammatory response of various diseases. Based on these findings, we aimed to explore the role of the CXCL1-CXCR2 axis in the repair process after peripheral nerve injury. Initially, we simulated sciatic nerve injury and observed an increased expression of CXCL1 and CXCR2 in the nerves of the injury group...
March 16, 2024: Molecular Immunology
https://read.qxmd.com/read/38492674/crosstalk-between-autophagy-and-inflammasomes-in-ricin-induced-inflammatory-injury
#17
JOURNAL ARTICLE
Shiji Zhang, Na Zhao, Suli Song, Yanchun Wang, Yan Wang, Chengbiao Sun, Mingxin Dong, Mengqi Huo, Na Xu, Wensen Liu, Guorui Li
Ricin (ricin toxin, RT) has the potential to cause damage to multiple organs and systems. Currently, there are no existing antidotes, vaccinations, or effective therapies to prevent or treat RT intoxication. Apart from halting protein synthesis, RT also induces oxidative stress, inflammation and autophagy. To explore the mechanisms of RT-induced inflammatory injury and specific targets of prevention and treatment for RT poisoning, we characterized the role of cross-talk between autophagy and NLRP3 inflammasome in RT-induced damage and elucidated the underlying mechanisms...
March 14, 2024: Toxicology and Applied Pharmacology
https://read.qxmd.com/read/38471922/-distribution-of-typical-resistant-bacteria-and-resistance-genes-in-source-water-of-the-middle-and-lower-reaches-of-the-yellow-river
#18
JOURNAL ARTICLE
Wei Min, Ming-Chang Gao, Shao-Fang Sun, Qian-Qian Song, Li-Ping Qiu
The Yellow River water of an urban area located in the middle and lower reaches of the Yellow River was taken as the research object, in which the seasonal and along-range distribution of total culturable bacteria, typical antibiotic resistant bacteria (amoxicillin resistant bacteria and sulfamethoxazole-resistant bacteria), and their corresponding typical resistance genes [ β -lactam resistance gene ( blaCTX-M ) and sulfamamide resistance genes ( sulI and sulⅡ ), as well as intⅠ1 were investigated...
February 8, 2024: Huan Jing Ke Xue= Huanjing Kexue
https://read.qxmd.com/read/38470454/association-between-cyp2c9-and-vkorc1-genetic-polymorphisms-and-efficacy-and-safety-of-warfarin-in-chinese-patients
#19
JOURNAL ARTICLE
Suli Zhang, Mingzhe Zhao, Shilong Zhong, Jiamin Niu, Lijuan Zhou, Bin Zhu, Haili Su, Wei Cao, Qinghe Xing, Hongli Yan, Xia Han, Qihua Fu, Qiang Li, Luan Chen, Fan Yang, Na Zhang, Hao Wu, Lin He, Shengying Qin
OBJECTIVES: Genetic variation has been a major contributor to interindividual variability of warfarin dosage requirement. The specific genetic factors contributing to warfarin bleeding complications are largely unknown, particularly in Chinese patients. In this study, 896 Chinese patients were enrolled to explore the effect of CYP2C9 and VKORC1 genetic variations on both the efficacy and safety of warfarin therapy. METHODS AND RESULTS: Univariate analyses unveiled significant associations between two specific single nucleotide polymorphisms rs1057910 in CYP2C9 and rs9923231 in VKORC1 and stable warfarin dosage (P < 0...
March 7, 2024: Pharmacogenetics and Genomics
https://read.qxmd.com/read/38462165/ythdf2-protein-stabilization-by-the-deubiquitinase-otub1-promotes-prostate-cancer-cell-proliferation-via-prss8-mrna-degradation
#20
JOURNAL ARTICLE
Xuefeng Zhao, Suli Lv, Neng Li, Qingli Zou, Lidong Sun, Tanjing Song
Prostate cancer is a leading cause of cancer-related mortality in males. Dysregulation of RNA Adenine N-6 methylation (m6A) contributes to cancer malignancy. m6A on mRNA may affect mRNA splicing, turnover, transportation and translation. m6A exerts these effects, at least partly, through dedicated m6A reader proteins, including YTHDF2. YTHDF2 is necessary for development while its dysregulation is seen in various cancers including prostate cancer. However, the mechanism underlying the dysregulation and function of YTHDF2 in cancer remains elusive...
March 8, 2024: Journal of Biological Chemistry
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