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https://www.readbyqxmd.com/read/28091974/clinical-trial-shows-lasting-function-of-a%C3%A2-new-moisturizing-cream-against-vaginal-dryness
#1
Hans-Heinrich Henneicke-von Zepelin, Ragna Williams, Wiebke Havemeister, Walter Wigger-Alberti, Klaus-Ulrich Nolte
Vaginal dryness and associated symptoms may occur in women of any age and are a frequent burden after menopause. The North American Menopause Society recommends long-acting non-hormonal vaginal creams as first-line therapy. A new type of such creams was developed (Remifemin® FeuchtCreme in Austria and Germany). This hormone-free cream contains hamamelis virginiana distillate and well-established vaginal cream ingredients. We explored its physical function and tolerability in an open interventional clinical trial...
January 13, 2017: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28079781/transcutaneous-nerve-stimulation-for-pain-relief-during-office-hysteroscopy-a-randomized-controlled-trial
#2
Juan F Lisón, Juan J Amer-Cuenca, Silvia Piquer-Martí, Vicente Benavent-Caballer, Gemma Biviá-Roig, Alejandro Marín-Buck
OBJECTIVE: To evaluate the pain-relieving effect of transcutaneous electrical nerve stimulation (TENS) during office-based hysteroscopy without sedation. METHODS: We conducted a randomized, double-blind, placebo-controlled trial. Participants were randomly assigned to the active TENS, placebo TENS, or control group. The active TENS intervention consisted of a varying high-frequency (80-100 Hz), 400-microseconds, individually adjusted, high-intensity TENS application with two self-adhesive electrodes placed parallel to the spinal cord at the T10-L1 and S2-S4 levels...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28070251/comparison-between-vaginal-royal-jelly-and-vaginal-estrogen-effects-on-quality-of-life-and-vaginal-atrophy-in-postmenopausal-women-a-clinical-trial-study
#3
Fatemeh Seyyedi, Mahmoud Rafiean Kopaei, Sepideh Miraj
OBJECTIVE: This study was conducted to evaluate the therapeutic effects of vaginal royal jelly and vaginal estrogen on quality of life and vaginal atrophy in postmenopausal women. METHODS: This double-blind randomized controlled clinical trial was carried out at gynecology and obstetrics clinics of Hajar Hospital of Shahrekord University of Medical Sciences (Iran) from January 2013 to January 2014. The study was conducted on married postmenopausal women between 50 and 65 years old...
November 2016: Electronic Physician
https://www.readbyqxmd.com/read/28068170/factors-associated-with-early-discontinuation-of-study-treatment-in-the-mammary-prevention-3-breast-cancer-chemoprevention-trial
#4
Olivia Meggetto, Elizabeth Maunsell, Rowan Chlebowski, Paul Goss, Dongsheng Tu, Harriet Richardson
Purpose Aromatase inhibitors are established breast cancer chemoprevention interventions. However, nonadherence remains a significant challenge. We investigated the association between worsening menopause-specific quality of life, baseline participant characteristics, and early treatment discontinuation within the Mammary Prevention.3 (MAP.3) breast cancer prevention trial. Methods In the MAP.3 randomized, placebo-controlled trial evaluating exemestane, participants completed the Menopause-Specific Quality of Life Questionnaire (MENQOL) at entry and at 6 months...
January 9, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28061774/metabolic-syndrome-and-depressive-symptoms-among-rural-northeast-general-population-in-china
#5
Shasha Yu, Hongmei Yang, Xiaofan Guo, Liqiang Zheng, Yingxian Sun
BACKGROUND: Previous researches aiming to estimate the association between metabolic syndrome and depressive symptoms come out with inconsistent results. Besides, most of them are conducted in the developed areas. There is lack of the data from rural China. The aim of this study is to confirm whether gender difference exists among the relationship between MetS, metabolic components and depressive symptoms in the rural Chinese population. METHODS: A cross-sectional analysis enrolled 11430 subjects' aged ≥35 from rural Northeast China...
January 6, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28056209/fractional-co2-laser-from-skin-rejuvenation-to-vulvo-vaginal-reshaping
#6
Maurizio Filippini, Ester Del Duca, Francesca Negosanti, Diletta Bonciani, Luca Negosanti, Mario Sannino, Giovanni Cannarozzo, Steven Paul Nisticò
BACKGROUND: The CO2 laser has become the gold standard treatment in dermatologic surgery for the treatment of a large number of skin and mucosal lesions. The introduction of the fractional micro-ablative technology represented an integration to the ablative resurfacing technique, reducing the healing time and the side effects. OBJECTIVE: Vaginal rejuvenation performed with this technique is a minimally invasive procedure that stimulates internal tissues of the female lower genital tract to regenerate the mucosa, improving tissue trophism and restoring the correct functionality...
December 30, 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28054115/-risk-and-benefit-of-nutritional-supplements-for-the-treatment-of-postmenopausal-complaints
#7
Patrick Diel, Anne Kurrat, Christina Oden, Lars Hanke
Menopause is for many females associated with an occurrence of a variety of health complaints and a decrease in quality in life. Hot flashes, sleep disturbances and a variety of other symptoms result in a strong psychological strain. Hormone replacement therapy for treatment of climacteric complaints is discussed controversially regarding associated side effects. This is a major reason to propose treatment with plant derived extracts and compounds as an alternative. Such compounds are available either as drugs but mostly as nutritional supplements...
January 4, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28053654/comparison-of-chemical-profiles-and-effectiveness-between-erxian-decoction-and-mixtures-of-decoctions-of-its-individual-herbs-a-novel-approach-for-identification-of-the-standard-chemicals
#8
H P Cheung, S W Wang, T B Ng, Y B Zhang, L X Lao, Z J Zhang, Y Tong, F W S Chung, S C W Sze
BACKGROUND: Identification of bioactive standard chemicals is a major challenge in the study of the Chinese medicinal formula. In particular, the chemical components may interact differently depending on the preparative methods, therefore affecting the amounts of bioactive components and their pharmacological properties in the medicinal formula. With the use of Erxian decoction (EXD) as a study model-a  well-known Chinese medicinal formula for treating menopausal symptoms, a novel and rapid approach in seeking standard chemicals has been established by differentially comparing the HPLC profiles and the menopause-related biochemical parameters of combined decoction of EXD (EXD-C) and mixtures of the decoctions of its individual herbs (EXD-S)...
2017: Chinese Medicine
https://www.readbyqxmd.com/read/28050596/an-ovarian-mature-cystic-teratoma-evolving-in-squamous-cell-carcinoma-a-case-report-and-review-of-the-literature
#9
REVIEW
C Goudeli, A Varytimiadi, N Koufopoulos, J Syrios, E Terzakis
Mature cystic teratomas (MCT), also known as dermoid cysts, are the most common ovarian germ cell tumors and the most common ovarian neoplasms in patients younger than 20 years. Malignant transformation (MT) is a rare complication of MCTs which may occur in 1-2% of the cases. Squamous cell carcinoma (SCC) is the most frequent histology arising from MCTs and its appearance depends on diverse risk factors such as patient's age, the size of the tumor and levels of serum tumor markers. Diagnosis and treatment constitute a big challenge due to the rarity and the aggressive course of this entity...
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28050408/effectiveness-of-self-instructional-module-on-coping-strategies-of-tri-dimensional-problems-of-premenopausal-women-a-community-based-study
#10
Prasanta Kumar Bhattacharya, Enu Boro, M D Jamil, Aakash Roy
INTRODUCTION: Pre-menopause in women presents with diverse symptoms, encompassing the tri-dimensional spheres of physical, social and psychological domains, which requires development of appropriate coping strategies to overcome these problems. AIM: To assess level of knowledge about tri-dimensional problems in pre-menopausal women and evaluate effectiveness of self instruction module on coping strategies of these problems by pre-test and post-test analysis. MATERIALS AND METHODS: In a cross-sectional, community based study, in pre-menopausal women aged 40-49years baseline knowledge of tridimensional problems was assessed in 300 pre-menopausal women, selected by convenient sampling after satisfying selection criteria, by a pre-formed questionnaire...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28049215/surgical-management-of-endometriosis-in-patients-with-chronic-pelvic-pain
#11
Rebecca Flyckt, Suejin Kim, Tommaso Falcone
Surgical approaches to endometriosis patients with chronic pelvic pain are multimodal and require individualization. Laparoscopic approaches are preferred over laparotomy when conservatively treating endometriosis via excision or ablation/fulguration of lesions. The available data support cystectomy over fenestration or fulguration for endometriomas; however, there may be associated decreases in ovarian reserve with endometrioma treatment. Presacral neurectomy may be useful in patients with midline pain and LUNA is not effective for the treatment of pelvic pain related to endometriosis...
January 3, 2017: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/28045986/evidence-for-cognitive-aging-in-midlife-women-study-of-women-s-health-across-the-nation
#12
Arun S Karlamangla, Margie E Lachman, WeiJuan Han, MeiHua Huang, Gail A Greendale
Although cross-sectional studies suggest that cognitive aging starts in midlife, few longitudinal studies have documented within-individual declines in cognitive performance before the seventh decade. Learning from repeat testing, or practice effects, can mask the decline in younger cohorts. In women, the menopause transition also affects test performance and can confound estimates of underlying decline. We designed this study to determine if, after controlling for practice effects, the menopause transition, and the symptoms associated with it, there is evidence of cognitive aging in midlife women...
2017: PloS One
https://www.readbyqxmd.com/read/28042734/vulvar-and-vaginal-atrophy-as-viewed-by-the-spanish-revive-participants-symptoms-management-and-treatment-perceptions
#13
S Palacios, M J Cancelo, C Castelo Branco, P Llaneza, F Molero, R Sanchez Borrego
OBJECTIVES: To gain a deeper comprehension of current vulvovaginal atrophy (VVA) knowledge among Spanish postmenopausal women. METHODS: An online survey (REVIVE) was conducted in four European countries with an overall sample of 768 participants included in Spain. Perceptions, experiences and needs of Spanish postmenopausal women in terms of sexual and vaginal health were reported. RESULTS: Vaginal dryness was the most common VVA symptom in Spain (81%)...
January 2, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28042728/a-brief-history-of-the-international-menopause-society
#14
R J Baber, J Wright
Although some understanding of post-reproductive life dates back to Ancient Greece, the term 'menopause' was only introduced in the early 1800s by a French physician. Notwithstanding familiarity with the condition at that time, treatments were largely ineffective, often harmful and never evidence-based, and it was not until 100 years later with the identification and description of estrogen and progesterone that effective treatments became available. So efficacious were hormone therapies for menopausal symptoms that their prescription was often recommended for all postmenopausal women regardless of their needs, wishes or health status...
January 2, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28042397/treatment-of-vaginal-atrophy-with-vaginal-estrogen-cream-in-menopausal-indian-women
#15
Maitri Shah, Zalak Karena, Sangita V Patel, Niyati Parmar, Pawan K Singh, Atul Sharma
OBJECTIVES: To measure the effect of vaginal estrogen cream in the treatment of vaginal atrophy in menopausal Indian women. METHODS: A total of 50 menopausal women aged between 40 and 80 years old with symptoms of vaginal atrophy were selected and treated with 0.5 g vaginal estrogen cream, twice weekly for 12 weeks. The women were followed-up monthly where symptom score, Genital Health Clinical Evaluation (GHCE) score, vaginal pH, and vaginal maturation index (VMI) were assessed and compared to baseline data...
January 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28041599/influence-of-equol-and-resveratrol-supplementation-on-health-related-quality-of-life-in-menopausal-women-a-randomized-placebo-controlled-study
#16
Sergio Davinelli, Giovanni Scapagnini, Fulvio Marzatico, Vincenzo Nobile, Nicola Ferrara, Graziamaria Corbi
OBJECTIVE: This study was designed to evaluate the effects of equol and resveratrol supplementation on health-related quality of life (HRQoL) in otherwise healthy menopausal women with hot flashes, anxiety and depressive symptoms. METHODS: Sixty recently menopausal women aged 50-55 years were randomized in a 12-week, placebo-controlled trial to receive 200mg of fermented soy containing 10mg of equol and 25mg of resveratrol (1 tablet/day). The primary outcome was the change in score on the Menopause Rating Scale (MRS), used to evaluate the severity of age-/menopause-related complaints...
February 2017: Maturitas
https://www.readbyqxmd.com/read/28035442/pelvic-organ-prolapse-prevalence-and-risk-factors-in-a-brazilian-population
#17
Wagner Horst, Juliana Barros do Valle, Jean Carl Silva, Carmem Luíza Lucht Gascho
INTRODUCTION AND HYPOTHESIS: Although pelvic organ prolapse (POP) is a prevalent condition among Brazilians, population-based epidemiological studies of POP are scarce. We studied POP in a population of women undergoing routine examination to determine its prevalence, distribution and relationship to risk factors. METHODS: This quantitative descriptive study surveyed 432 women, based on prolapse prevalence, who sought routine care and were assessed for prolapse staging using the Pelvic Organ Prolapse Quantification system (POP-Q)...
December 29, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/28035371/the-anti-metastatic-effects-of-the-phytoestrogen-arctigenin-on-human-breast-cancer-cell-lines-regardless-of-the-status-of-er-expression
#18
Thressi Maxwell, So-Young Chun, Kyu-Shik Lee, Soyoung Kim, Kyung-Soo Nam
Arctigenin is a plant lignan extracted from Arctium lappa that has been shown to have estrogenic properties. In spite of the health benefits of phytoestrogens reducing the risk of osteoporosis, heart disease, and menopausal symptoms, its benefits against the risk of breast cancer have not been fully elucidated. Thus, we investigated the effects of arctigenin on metastasis of breast cancer using both estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 human breast cancer cell lines to see if the effects are dependent on the status of ER expression...
December 29, 2016: International Journal of Oncology
https://www.readbyqxmd.com/read/28030937/predictors-of-the-quality-of-life-of-women-in-peri-menopausal-period
#19
Katarzyna Kanadys, Anna Wiktor-Stoma, Magdalena Lewicka, Magdalena Sulima, Henryk Wiktor
INTRODUCTION: The peri-menopausal period is the time of many biological, psychological and social changes. The quality of life of women in this period may be conditioned by many factors, and analysis of these factors may indicate the optimum directions of prophylactic and educational actions. OBJECTIVE: Analysis of selected predictive factors of the quality of life of women in the peri-menopausal period. MATERIALS AND METHOD: The study covered 268 peri-menopausal women...
23, 2016: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28029675/an-overview-of-menopausal-symptoms-in-a-district-hospital-of-nepal
#20
S Gupta, K Acharya, P Srivastav, P K Gurung, N Gupta
INTRODUCTION: Menopause is a universal reproductive phenomenon which confirms the end of fertility of the women. The objectives of this study were to establish the age of natural menopause and to identify the prevalence of menopausal symptoms among the rural women attending district hospital of Nepal. METHODS: This present study is a hospital based, observational cross-sectional study conducted in Outpatient department of Lamjung District Hospital, Lamjung, Nepal...
October 2016: JNMA; Journal of the Nepal Medical Association
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