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https://www.readbyqxmd.com/read/28643614/consensus-statement-for-non-hormonal-based-treatments-for-menopausal-symptoms
#1
Jane Woyka
Since the June 2014 consensus statement published in Post Reproductive Health we have had definitive guidelines on menopause treatment from the National Institute for Clinical Excellence in November 2015. These included robust and evidence based information about many non-estrogen based treatments, which are particularly useful for patients who do not wish to take hormone replacement therapy, or who have medical contraindications to hormonal therapy such as hormone dependent cancers. Whilst none of these therapies is as effective as hormones, we must be able to advise patients about them and recommend which treatments may be helpful for individual women...
June 2017: Post Reproductive Health
https://www.readbyqxmd.com/read/28643612/cognitive-behaviour-therapy-cbt-for-menopausal-symptoms-information-for-women-myra-hunter-and-melanie-smith-in-collaboration-with-the-british-menopause-society
#2
(no author information available yet)
No abstract text is available yet for this article.
June 2017: Post Reproductive Health
https://www.readbyqxmd.com/read/28643610/cognitive-behaviour-therapy-cbt-for-menopausal-symptoms-information-for-gps-and-health-professionals
#3
Myra Hunter, Melanie Smith In Collaboration With The British Menopause Society
No abstract text is available yet for this article.
June 2017: Post Reproductive Health
https://www.readbyqxmd.com/read/28640166/missing-documentation-in-breast-cancer-survivors-genitourinary-syndrome-of-menopause
#4
Elise D Cook, Elena I Iglehart, George Baum, Leslie L Schover, Lonzetta L Newman
OBJECTIVE: Breast cancer survivors often take hormonal treatments to prevent the recurrence of breast cancer, particularly aromatase inhibitors that can worsen the symptoms of genitourinary syndrome of menopause (GSM) such as dyspareunia, dysuria, and urinary incontinence, all of which may adversely affect survivors' quality of life. Few breast cancer survivors experiencing GSM receive adequate assessment or treatment. METHODS: In this descriptive study, we reviewed medical records for documented GSM and any treatments administered or referrals for treatment in 800 female patients who visited the Breast Cancer Survivorship Clinic at a comprehensive cancer center between July 1, 2010 and June 30, 2011, either at least 5 years after completion of treatment for invasive breast cancer or at least 6 months after completion of treatment for ductal carcinoma in situ...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28640161/combined-data-of-intravaginal-prasterone-against-vulvovaginal-atrophy-of-menopause
#5
Fernand Labrie, David F Archer, Céline Martel, Mario Vaillancourt, Marlene Montesino
OBJECTIVE: To analyze the effects of intravaginal prasterone obtained in the three randomized clinical studies performed in postmenopausal women suffering from moderate to severe (MS) dyspareunia due to vulvovaginal atrophy (VVA). METHODS: In three independent 12-week prospective, randomized, double-blind, and placebo-controlled clinical studies, the effect of daily intravaginal 0.50% (6.5 mg) prasterone was examined on four co-primary objectives in women having MS pain during sexual activity (dyspareunia), identified as their most bothersome symptom (MBS) of VVA at baseline...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28640160/vasomotor-symptoms-in-women-in-asia-appear-comparable-with-women-in-western-countries-a-systematic-review
#6
Rakibul M Islam, Robin J Bell, Farwa Rizvi, Susan R Davis
OBJECTIVE: There is a belief that menopausal symptoms, particularly vasomotor symptoms (VMS), are a Western phenomena and less likely to be experienced in women in Asian countries. This systematic review of the literature was undertaken to evaluate the prevalence of VMS in Asian countries. METHODS: MEDLINE, EMBASE, PsycINFO, CINAHL, SCOPUS, and Google scholar were searched systematically for relevant population-based prevalence studies published between 1981 and 2016...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28640159/transcranial-direct-current-stimulation-effects-on-menopausal-vasomotor-symptoms
#7
Mônia Steigleder Bianchi, Charles Francisco Ferreira, Felipe Fregni, Pedro Schestatsky, Wolnei Caumo, Maria Celeste Osório Wender
OBJECTIVE: To assess the effects of transcranial direct current stimulation (tDCS) compared with tDCS-sham on vasomotor symptoms of postmenopausal women. METHODS: Postmenopausal women (N = 30), aged between 45 and 68 years, with at least four episodes of vasomotor symptoms per day, were recruited from a specialized outpatient clinic at a tertiary hospital in the south of Brazil and through a media call after inclusion and exclusion criteria were ensured. Active and tDCS-sham were administered over the motor cortex position (anode electrode) and contralateral supraorbital region (cathode electrode) for 10 consecutive days, except weekends...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28640157/association-of-visceral-fat-area-with-the-presence-of-depressive-symptoms-in-chinese-postmenopausal-women-with-normal-glucose-tolerance
#8
Qin Xiong, Xiang Hu, Yiting Xu, Xueli Zhang, Xiaoping Pan, Yunfeng Xiao, Xiaojing Ma, Yuqian Bao, Weiping Jia
OBJECTIVE: Depression is one of the most common mental disorders, and women are more vulnerable to depression than men, particularly during stages of hormonal fluctuations. After menopause, fat accumulation shifts from the subcutaneous area to the visceral area, and the risk of metabolic disorder increases in parallel. The present study aimed to evaluate the association between abdominal fat distribution and the presence of depressive symptoms in postmenopausal women. METHODS: Visceral fat area (VFA) was detected by magnetic resonance imaging...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28640154/vaginal-microbiota-and-genitourinary-menopausal-symptoms-a-cross-sectional-analysis
#9
Caroline M Mitchell, Sujatha Srinivasan, Xiang Zhan, Michael C Wu, Susan D Reed, Katherine A Guthrie, Andrea Z LaCroix, Tina Fiedler, Matthew Munch, Congzhou Liu, Noah G Hoffman, Ian A Blair, Katherine Newton, Ellen W Freeman, Hadine Joffe, Lee Cohen, David N Fredricks
OBJECTIVE: To examine associations between the composition of the vaginal microbiota and genitourinary menopausal symptoms, serum estrogen, and vaginal glycogen. METHODS: For this cross-sectional study, 88 women aged 40 to 62 years, enrolled in a hot flash treatment trial, provided vaginal swabs and a blood sample at enrollment. Bacterial communities were characterized using 16S rRNA PCR and deep sequencing targeting the V3-V4 region. Quantities of Lactobacillus crispatus and Lactobacillus iners were measured using qPCR...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28639461/hormonal-contraception-and-breast-cancer-what-more-do-we-need-to-know
#10
Jo Marsden
Most women use hormonal contraception for more than 30 years and for many, this may involve exposure in their older reproductive years when baseline breast cancer risk rises steeply. Overall, the risk of breast cancer diagnosis with exposure to hormonal contraception is very small and outweighed by its contraceptive benefits but despite this, there are still outstanding questions for all methods used in clinical practice due to paucity of available evidence, lack of which should not be taken to imply safety...
January 1, 2017: Post Reproductive Health
https://www.readbyqxmd.com/read/28635973/deconstructing-decisions-to-initiate-maintain-or-discontinue-adjuvant-endocrine-therapy-in-breast-cancer-survivors-a-mixed-methods-study
#11
Shirley M Bluethmann, Caitlin C Murphy, Jasmin A Tiro, Michelle A Mollica, Sally W Vernon, Leona Kay Bartholomew
PURPOSE/OBJECTIVES: Adjuvant endocrine therapy (AET) has been shown to improve survival in hormone receptor-positive breast cancer survivors, but as many as half do not complete recommended treatment. Management of medication-related side effects and engagement with providers are two potentially modifiable factors, but their associations with adherence are not well understood. The aims were to build on survey results to qualitatively explore survivors' experiences with prescribed AET to (a) describe appraisal and management of AET side effects and (b) deconstruct decisions to initiate, discontinue, or maintain AET...
May 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28634732/engineering-poly-lactic-co-glycolic-acid-plga-micro-and-nano-carriers-for-controlled-delivery-of-17%C3%AE-estradiol
#12
Alesia V Prakapenka, Heather A Bimonte-Nelson, Rachael W Sirianni
With menopause, circulating levels of 17β-estradiol (E2) markedly decrease. E2-based hormone therapy is prescribed to alleviate symptoms associated with menopause. E2 is also recognized for its beneficial effects in the central nervous system (CNS), such as enhanced cognitive function following abrupt hormonal loss associated with ovariectomy. For women with an intact uterus, an opposing progestogen component is required to decrease the risk of developing endometrial hyperplasia. While adding an opposing progestogen attenuates these detrimental effects on the uterus, it can attenuate the beneficial effects of E2 in the CNS...
June 20, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28629256/managing-menopause-in-women-living-with-hiv-a-survey-of-primary-care-practitioners
#13
Mimie Chirwa, Richard Ma, Cristina Guallar, Shema Tariq
Objective One in three women living with HIV (WLHIV) in the UK is aged 45-56, and therefore of potentially menopausal age. Little is known about the management of menopause in WLHIV in primary care. We aim to describe current knowledge and practice in the management of menopause in WLWH among primary care practitioners (PCPs). Methods A questionnaire-based study of 88 PCPs attending two sexual and reproductive health conferences. Results Almost all respondents (n = 87, 99%) routinely managed women with menopause-related symptoms; however, only 18 (20%) reported having managed menopause in WLHIV...
January 1, 2017: Post Reproductive Health
https://www.readbyqxmd.com/read/28628428/eraas-for-menopause-treatment-welcome-the-designer-estrogens
#14
REVIEW
Heather D Hirsch, Elim Shih, Holly L Thacker
Estrogen receptor agonist-antagonists (ERAAs) selectively inhibit or stimulate estrogen-like action in targeted tissues. This review summarizes how ERAAs can be used in combination with an estrogen or alone to treat menopausal symptoms (vasomotor symptoms, genitourinary syndrome of menopause), breast cancer or the risk of breast cancer, osteopenia, osteoporosis, and other female midlife concerns.
June 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28625396/management-of-menopausal-symptoms-in-women-with-gynecologic-cancers
#15
REVIEW
Marcela G Del Carmen, Laurel W Rice
OBJECTIVE: Women with gynecologic malignancies will be cured or may become long-term survivors. Management of menopausal symptoms is important in addressing their quality of life. We review the benefit and safety of hormone therapy use in these patients. METHODS: MEDLINE was searched for studies on menopause management published in English through December of 2016. RESULTS: Available data suggest that short-term use of hormone therapy in gynecologic cancer patients who do not have an estrogen-dependent malignancy do not adversely impact oncologic outcome and results in improvement of menopausal vasomotor and genitourinary symptoms...
June 15, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28622875/does-the-severity-of-overactive-bladder-symptoms-correlate-with-risk-for-female-sexual-dysfunction
#16
Cássia Raquel Teatin Juliato, Iane Glauce Ribeiro Melotti, Luiz Carlos Santos Junior, Luiz Gustavo Oliveira Britto, Cássio Luiz Zanettini Riccetto
BACKGROUND: Several studies have associated overactive bladder (OAB) with female sexual dysfunction (FSD); however, there are no reports using a quantitative approach to measure OAB severity and to relate OAB to the risk of FSD. AIM: To evaluate women with OAB and to correlate the severity of their urinary symptoms with their sexual function. METHODS: This cross-sectional study included 267 women older than 18 years with untreated OAB. All subjects completed the International Consultation on Incontinence Questionnaire Overactive Bladder (ICIQ-OAB) and the Female Sexual Function Index (FSFI)...
June 13, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28622476/the-effect-of-transdermal-estrogen-patch-use-on-cardiovascular-outcomes-a-systematic-review
#17
Prema Bezwada, Atif Shaikh, Deepika Misra
BACKGROUND: Vasomotor symptoms are the most commonly reported menopausal symptoms. Hormone therapy has been widely used to relieve postmenopausal symptoms. With studies suggesting an increased risk of cardiovascular events and breast cancer with oral hormone therapy use, there has been reluctance to use it. The transdermal estrogen patch provides relief from menopausal symptoms. However, there are limited data on mortality and cardiovascular outcomes, while on the transdermal estrogen patch...
June 16, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28622040/analysis-of-differential-genetic-expression-in-endometrial-polyps-of-postmenopausal-women
#18
J K Troncon, J Meola, F J Candido-Dos-Reis, O B Poli-Neto, A A Nogueira, J C Rosa-E-Silva
OBJECTIVES: To evaluate the expression of four genetic markers (PTEN, BCL2, MLH1, and CTNNB1), linked to endometrial carcinogenesis, in endometrial polyps of patients with and without postmenopausal bleeding in order to determine whether symptomatic endometrial polyps have a genetic phenotype similar to that of endometrial cancer. METHODS: Samples were obtained hysteroscopically from endometrial polyps of postmenopausal patients, and the expression of genetic markers involved in the pathogenesis of endometrial cancer (PTEN, BCL2, MLH1, and CTNNB1) was analyzed...
June 16, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28620500/lugol-s-solution-induced-painless-thyroiditis
#19
Ji Wei Yang, Jacques How
Lugol's solution is usually employed for a limited period for thyroidectomy preparation in patients with Graves' disease and for the control of severe thyrotoxicosis and thyroid storm. We describe a rare case of Lugol's solution-induced painless thyroiditis. In November 2014, a 59-year-old woman was prescribed Lugol's solution four drops per day for the alleviation of menopausal symptoms. She was referred to our clinic in June 2015 for fatigue, hair loss, and a 20-lb weight loss without thyroid pain or discomfort...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28619302/chinese-herbal-medicine-for-treating-menopausal-symptoms-in-london-women-developing-a-good-practice-protocol-via-the-factor-analysis-of-prescribing-patterns-in-a-clinical-study
#20
Volker Scheid, Veronica Tuffrey, Mark Bovey
The objective of the study described in this paper was to define Chinese medicine formula patterns for the treatment of menopausal women in London. These formula patterns are intended to inform the development of best practice guidelines for a future pragmatic randomised controlled trial, with the ultimate goal of evaluating the possibility of integrating Chinese medicine treatment strategies for menopausal symptoms into the UK National Health Service. Data from a clinical study that had demonstrated the effectiveness and safety of Chinese medicine in treating 117 perimenopausal women at the Westminster University Polyclinic in London were analysed for symptom occurrence and herb use...
June 2017: Complementary Therapies in Medicine
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