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Michael Richardson

Gary M LiMarzi, Kurt F Scherer, Michael L Richardson, David R Warden, Christopher W Wasyliw, Jack A Porrino, Christopher R Pettis, Gideon Lewis, Christopher C Mason, Laura W Bancroft
A variety of surgical procedures exist for repair of both traumatic and degenerative osseous and soft-tissue pathologic conditions involving the foot and ankle. It is necessary for the radiologist to be familiar with these surgical procedures, so as to assess structural integrity, evaluate for complicating features, and avoid diagnostic pitfalls. Adequate interpretation of postoperative changes often requires access to surgical documentation to evaluate not only the surgery itself but the expected timeline for resolution of normal postoperative changes versus progressive disease...
October 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
T Tony Trinh, Nelly Yatich, Richard Ngomoa, Christine J McGrath, Barbra A Richardson, Samah R Sakr, Agnes Langat, Grace C John-Stewart, Michael H Chung
BACKGROUND: Disclosure of HIV serostatus can have significant benefits for people living with HIV/AIDS. However, there is limited data on whether partner disclosure influences ART treatment response. METHODS: We conducted a retrospective cohort study of newly diagnosed, ART-naïve HIV-infected adults (>18 years) who enrolled at the Coptic Hope Center in Nairobi, Kenya between January 1st 2009 and July 1st 2011 and initiated ART within 3 months. Analysis was restricted to adults who reported to have either disclosed or not disclosed their HIV status to their partner...
2016: PloS One
James R Churilla, Tammie M Johnson, Michael R Richardson, Bethany D Williams
OBJECTIVES: Examine the odds of adults reporting physical inactivity (PI) across six body mass index (BMI) categories. METHODS: We used data from the 2013 Behavioral Risk Factor Surveillance System. Six BMI categories were used. RESULTS: The odds of reporting PI in underweight men and men in the class I, II, and III obesity categories were 1.65 (95% confidence interval [CI] 1.35-2.02), 1.30 (95% CI 1.21-1.39), 1.73 (95% CI 1.58-1.90), and 2...
October 2016: Southern Medical Journal
Michael E Steinhaus, Alexander S McLawhorn, Shawn S Richardson, Patrick Maher, David J Mayman
BACKGROUND: Proper alignment of total knee arthroplasty (TKA) is essential for TKA function and may reduce the risk of aseptic failure. Technologies that prevent malalignment may reduce the risk of revision surgery. QUESTIONS/PURPOSES: The purpose of this study was to compare two competing TKA systems that purport improved alignment: patient-specific instrumentation (PSI), and a handheld portable navigation device (NAV). METHODS: After IRB approval, 49 consecutive PSI TKAs (40 patients) were matched based on preoperative characteristics to 49 NAV TKAs (40 patients) performed by a single surgeon...
October 2016: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
Philip G Richardson, Jaimi Greenslade, Jonathon Isoardi, Michael Davey, Mark Gillett, Alicia Tucker, Sharon Klim, Anne-Maree Kelly, Ibrahim Abdelmahmoud
OBJECTIVE: We investigated and compared the importance of the considerations and discussions when withdrawing and withholding life-sustaining healthcare between emergency physicians (EP) and emergency registrars (ER). METHODS: This was a sub-study of a prospective cross-sectional questionnaire-based case series conducted in six EDs. Primary outcomes were, which of the discussion and considerations, were rated most important by EP and ER in the decision-making process...
October 4, 2016: Emergency Medicine Australasia: EMA
Corrado Cancedda, Sheila M Davis, Kerry L Dierberg, Jonathan Lascher, J Daniel Kelly, Mohammed Bailor Barrie, Alimamy Philip Koroma, Peter George, Adikali Alpha Kamara, Ronald Marsh, Manso S Sumbuya, Cameron T Nutt, Kirstin W Scott, Edgar Thomas, Katherine Bollbach, Andrew Sesay, Ahmidu Barrie, Elizabeth Barrera, Kathryn Barron, John Welch, Nahid Bhadelia, Raphael G Frankfurter, Ophelia M Dahl, Sarthak Das, Rebecca E Rollins, Bryan Eustis, Amanda Schwartz, Piero Pertile, Ilias Pavlopoulos, Allan Mayfield, Regan H Marsh, Yusupha Dibba, Danielle Kloepper, Andrew Hall, Karin Huster, Michael Grady, Kimberly Spray, David A Walton, Fodei Daboh, Cora Nally, Sahr James, Gabriel S Warren, Joyce Chang, Michael Drasher, Gina Lamin, Sherry Bangura, Ann C Miller, Annie P Michaelis, Ryan McBain, M Jana Broadhurst, Megan Murray, Eugene T Richardson, Ted Philip, Gary L Gottlieb, Joia S Mukherjee, Paul E Farmer
An epidemic of Ebola virus disease (EVD) beginning in 2013 has claimed an estimated 11 310 lives in West Africa. As the EVD epidemic subsides, it is important for all who participated in the emergency Ebola response to reflect on strengths and weaknesses of the response. Such reflections should take into account perspectives not usually included in peer-reviewed publications and after-action reports, including those from the public sector, nongovernmental organizations (NGOs), survivors of Ebola, and Ebola-affected households and communities...
October 15, 2016: Journal of Infectious Diseases
Simon Chiosea, Sylvia L Asa, Michael A Berman, Sally E Carty, Louanne Currence, Steven Hodak, Yuri E Nikiforov, Mary S Richardson, Raja R Seethala, Lynette M Sholl, Lester D R Thompson, Bruce M Wenig, Frank Worden
No abstract text is available yet for this article.
September 28, 2016: Archives of Pathology & Laboratory Medicine
Brett S Nickerson, Michael R Esco, Phillip A Bishop, Randall Schumacker, Mark Richardson, Michael V Fedewa, Jonathan E Wingo, Bailey A Welborn
The purpose of this study was to compare body fat percentage (BF%) and fat-free mass (FFM) values from bioelectrical impedance analysis (BIA) equations to values determined from a four-compartment (4C) model. Eighty-two adults (42 men and 40 women) volunteered to participate (age = 23 ± 5 years). BF% and FFM were estimated from previously developed BIA equations by Chumlea et al. (BIACH), Deurenberg et al. (BIADE), Kyle et al. (BIAKYLE), and Sun et al. (BIASUN). 4C model body composition was derived from underwater weighing for body density, dual energy X-ray absorptiometry for bone mineral content, and bioimpedance spectroscopy for total body water...
September 20, 2016: Journal of Strength and Conditioning Research
Samuel Justin Sinclair, Michael J Roche, Christina Temes, Christina Massey, Wei-Jean Chung, Michelle Stein, Laura Richardson, Mark Blais
The current study sought to develop and validate a new measure of chronic suicide risk (the S_Chron) from the Personality Assessment Inventory in a mixed sample of psychiatric inpatients and outpatients. In an initial development sample (N=397), hierarchical logistic regression identified six PAI variables uniquely associated with multiple versus single/no prior suicide attempts after controlling for sample demographics: Negative Impression Management, Situational Stress, Mania - Grandiosity, Borderline - Negative Relationships, Borderline - Self-Harm, and Antisocial Behaviors...
November 30, 2016: Psychiatry Research
Sam Behjati, Gunes Gundem, David C Wedge, Nicola D Roberts, Patrick S Tarpey, Susanna L Cooke, Peter Van Loo, Ludmil B Alexandrov, Manasa Ramakrishna, Helen Davies, Serena Nik-Zainal, Claire Hardy, Calli Latimer, Keiran M Raine, Lucy Stebbings, Andy Menzies, David Jones, Rebecca Shepherd, Adam P Butler, Jon W Teague, Mette Jorgensen, Bhavisha Khatri, Nischalan Pillay, Adam Shlien, P Andrew Futreal, Christophe Badie, Ultan McDermott, G Steven Bova, Andrea L Richardson, Adrienne M Flanagan, Michael R Stratton, Peter J Campbell
Ionizing radiation is a potent carcinogen, inducing cancer through DNA damage. The signatures of mutations arising in human tissues following in vivo exposure to ionizing radiation have not been documented. Here, we searched for signatures of ionizing radiation in 12 radiation-associated second malignancies of different tumour types. Two signatures of somatic mutation characterize ionizing radiation exposure irrespective of tumour type. Compared with 319 radiation-naive tumours, radiation-associated tumours carry a median extra 201 deletions genome-wide, sized 1-100 base pairs often with microhomology at the junction...
September 12, 2016: Nature Communications
Emily Benham, William Richardson, Jonathan Dort, Henry Lin, A Michael Tummers, Travelyan M Walker, Dimitrios Stefanidis
BACKGROUND: Surgical safety checklists reduce perioperative complications and mortality. Given that minimally invasive surgery (MIS) is dependent on technology and vulnerable to equipment failure, SAGES and AORN partnered to create a MIS checklist to optimize case flow and minimize errors. The aim of this project was to evaluate the effectiveness of the SAGES/AORN checklist in preventing disruptions and determine its ease of use. METHODS: The checklist was implemented across four institutions and completed by the operating team...
September 7, 2016: Surgical Endoscopy
Kelsey Richardson, David Haynes, Anthony Talouli, Michael Donoghue
Fisheries observer data recorded between 2003 and 2015 on-board purse seine and longline vessels operating in the Western and Central Pacific Ocean reported more than 10 000 pollution incidents within the exclusive economic zones (EEZs) of 25 Pacific countries and territories, and in international waters. A majority of the reported purse seine pollution incidents related to dumping of plastics waste. Other common pollution incidents related to oil spillages and to abandoned, lost or dumped fishing gear. Data analysis highlighted the need for increased monitoring, reporting, and enforcement of pollution violations by all types of fishing vessels operating in the Pacific region; a regional outreach and compliance assistance programme on marine pollution prevention and improvements in Pacific port waste reception facilities...
August 27, 2016: Ambio
Jeffrey Aalders, Shaukat Ali, Tom J de Jong, Michael K Richardson
In previous publications, we described the population incidence of abnormalities in zebrafish larvae exposed to toxicants. Here, we examine the phenomenon of clustering or co-occurrence of abnormalities in individual larva. Our aim is to see how this clustering can be used to assess the specificity and severity of teratogenic effect. A total of 11,214 surviving larvae, exposed continuously from 1 day postfertilization (dpf) to one of 60 toxicants, were scored at 5 dpf for the presence of eight different abnormal phenotypes...
August 25, 2016: Zebrafish
Cele E Richardson, Michael Gradisar, Michelle A Short, Christin Lang
Adolescents are vulnerable to inadequate sleep due to a unique constellation of risk factors. In particular, the puberty-related phase delay in the timing of the circadian system postpones the onset of sleep. Resultantly, disordered sleep is common among teenagers and young adults, with the most common sleep problem being delayed sleep wake-phase disorder (DSWPD). Although current treatments for DSWPD show promise, novel ways to improve our youth's sleep are needed. The purpose of this review is to critically evaluate the evidence for the role of exercise as a method to shift and/or regulate circadian timing, and thus improve sleep, in adolescents and young adults...
July 11, 2016: Sleep Medicine Reviews
Elissa M Aminoff, Yuanning Li, John A Pyles, Michael J Ward, R Mark Richardson, Avniel S Ghuman
Visual recognition requires connecting perceptual information with contextual information and existing knowledge. The ventromedial temporal cortex (VTC), including the medial fusiform, has been linked with object recognition, paired associate learning, contextual processing, and episodic memory, suggesting that this area may be critical in connecting visual processing, context, knowledge and experience. However, evidence for the link between associative processing, episodic memory, and visual recognition in VTC is currently lacking...
October 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Charlotte Richardson, Nadine Hachach-Haram, Michael Billingsley, Norma Timoney, Will Grant, Paul Gerarchi, Jonathon Collier, Simon Eccles, Richard Young, Niall Kirkpatrick
BACKGROUND: Education and training of local healthcare staff is a crucial component of a surgical mission. Facing The World (FTW) is a UK-based craniofacial charity that provides facial reconstructive surgery to children with complex, craniofacial anomalies. As part of its global initiative, FTW has developed a training outreach program in Vietnam. The aim of this study was to analyze feedback data to evaluate the educational value of the training program and identify areas for improvement...
October 2016: Journal of Craniofacial Surgery
Paul Leger, Sanika Chirwa, Megan Turner, Danielle M Richardson, Paxton Baker, Michael Leonard, Husamettin Erdem, Lana Olson, David W Haas
BACKGROUND: Efavirenz frequently causes central nervous system (CNS) symptoms. We evaluated genetic associations with efavirenz discontinuation for CNS symptoms within 12 months of treatment initiation. METHODS: Patients had initiated efavirenz-containing regimens at an HIV primary care clinic in the Southeastern United States and had at least 12 months of follow-up data. Polymorphisms in CYP2B6 and CYP2A6 defined efavirenz metabolizer categories. Genome-wide genotyping enabled adjustment for population stratification...
October 2016: Pharmacogenetics and Genomics
Catherine M Sweeney-Reed, Tino Zaehle, Jürgen Voges, Friedhelm C Schmitt, Lars Buentjen, Klaus Kopitzki, Alan Richardson-Klavehn, Hermann Hinrichs, Hans-Jochen Heinze, Robert T Knight, Michael D Rugg
The data presented here comprise clinical, neuropsychological, and intrathalamic electrophysiological data from 7 patients with pharmacoresistant focal epilepsy and are related to the article "Pre-stimulus thalamic theta power predicts human memory formation" C.M. Sweeney-Reed, T. Zaehle, J. Voges, F.C. Schmitt, L. Buentjen, K. Kopitzki, et al. (2016) [1]. The patients participated in a memory paradigm after receiving electrodes implanted in the DMTN due to the surgical approach taken in electrode insertion for deep brain stimulation of the anterior thalamic nucleus...
September 2016: Data in Brief
Michael L Richardson
OBJECTIVE: One of the most important jobs of a radiologist is to pick the most appropriate imaging test for a particular clinical situation. Making a proper selection sometimes requires statistical analysis. The objective of this article is to introduce a simple graphic technique, an ROC plot that has been divided into zones of mostly bad imaging efficacy (ZOMBIE, hereafter referred to as the "zombie plot"), that transforms information about imaging efficacy from the numeric domain into the visual domain...
August 9, 2016: AJR. American Journal of Roentgenology
Adam Shlien, Keiran Raine, Fabio Fuligni, Roland Arnold, Serena Nik-Zainal, Serge Dronov, Lira Mamanova, Andrej Rosic, Young Seok Ju, Susanna L Cooke, Manasa Ramakrishna, Elli Papaemmanuil, Helen R Davies, Patrick S Tarpey, Peter Van Loo, David C Wedge, David R Jones, Sancha Martin, John Marshall, Elizabeth Anderson, Claire Hardy, Violetta Barbashina, Samuel A J R Aparicio, Torill Sauer, Øystein Garred, Anne Vincent-Salomon, Odette Mariani, Sandrine Boyault, Aquila Fatima, Anita Langerød, Åke Borg, Gilles Thomas, Andrea L Richardson, Anne-Lise Børresen-Dale, Kornelia Polyak, Michael R Stratton, Peter J Campbell
Disordered transcriptomes of cancer encompass direct effects of somatic mutation on transcription, coordinated secondary pathway alterations, and increased transcriptional noise. To catalog the rules governing how somatic mutation exerts direct transcriptional effects, we developed an exhaustive pipeline for analyzing RNA sequencing data, which we integrated with whole genomes from 23 breast cancers. Using X-inactivation analyses, we found that cancer cells are more transcriptionally active than intermixed stromal cells...
August 16, 2016: Cell Reports
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