keyword
MENU ▼
Read by QxMD icon Read
search

NSA

keyword
https://www.readbyqxmd.com/read/28800269/the-connections-among-suicidal-behavior-lipid-profile-and-low-grade-inflammation-in-patients-with-major-depressive-disorder-a-specific-relationship-with-the-neutrophil-to-lymphocyte-ratio
#1
Okan Ekinci, Asli Ekinci
OBJECTIVES: The role of inflammation and lipid metabolism in the pathophysiology of suicidal behavior has received particular attention in recent years. The neutrophil-to-lymphocyte ratio (NLR) has been suggested as a new and more reliable indicator of low-grade inflammation. NLR has been found to be altered in major depressive disorder (MDD) and has been related to various factors, including chronic stress and impulsivity that were previously reported to be related to suicidal behavior...
August 11, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28767613/effect-of-greater-trochanteric-epiphysiodesis-after-femoral-varus-osteotomy-for-lateral-pillar-classification-b-and-b-c-border-legg-calv%C3%A3-perthes-disease-a-retrospective-observational-study
#2
Keun-Sang Kwon, Sung Il Wang, Ju-Hyung Lee, Young Jae Moon, Jung Ryul Kim
This is a retrospective observational study. Greater trochanteric epiphysiodesis (GTE) has been recommended to prevent Trendelenburg gait and limitation of the hip joint motion due to trochanteric overgrowth after femoral varus osteotomy (FVO) in Legg-Calvé-Perthes disease (LCPD). However, capital femoral physeal arrest frequently occurs in patients with severe disease (lateral pillar C), so GTE might not be as effective in these patients. The aim of this study was to compare trochanteric growth inhibition due to GTE after FVO between 2 age groups (<8 or >8 years) in patients with lateral pillar B and B/C border LCPD and evaluate the effectiveness of GTE compared with the normal, unaffected hip...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28767435/the-degradation-of-mixed-lineage-kinase-domain-like-protein-promotes-neuroprotection-after-ischemic-brain-injury
#3
Yanlong Zhou, Beiqun Zhou, Hui Tu, Yan Tang, Chen Xu, Yanbo Chen, Zhong Zhao, Zhigang Miao
Mixed lineage kinase domain-like (MLKL) protein was recently found to play a critical role in necrotic cell death. To explore its role in neurological diseases, we measured MLKL protein expression after ischemia injury in a mouse model. We found that MLKL expression significantly increased 12 h after ischemia/reperfusion (I/R) injury with peak levels at 48 h. Inhibition of MLKL by intraperitoneal administration of NSA significantly reduced infarct volume and improved neurological deficits after 75 min of ischemia and 24 h of reperfusion...
July 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28728556/influence-of-staphylococcus-aureus-on-outcomes-after-valvular-surgery-for-infective-endocarditis
#4
Sang Myung Han, Robert A Sorabella, Sowmya Vasan, Mark Grbic, Daniel Lambert, Rahul Prasad, Catherine Wang, Paul Kurlansky, Michael A Borger, Rachel Gordon, Isaac George
BACKGROUND: As Staphylococcus aureus (SA) remains one of the leading cause of infective endocarditis (IE), this study evaluates whether S. aureus is associated with more severe infections or worsened outcomes compared to non-S. aureus (NSA) organisms. METHODS: All patients undergoing valve surgery for bacterial IE between 1995 and 2013 at our institution were included in this study (n = 323). Clinical data were retrospectively collected from the chart review. Patients were stratified according to the causative organism; SA (n = 85) and NSA (n = 238)...
July 20, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28725015/all-printed-highly-sensitive-2d-mos2-based-multi-reagent-immunosensor-for-smartphone-based-point-of-care-diagnosis
#5
Memoon Sajid, Ahmed Osman, Ghayas Uddin Siddiqui, Hyun Bum Kim, Soo Wan Kim, Jeong Bum Ko, Yoon Kyu Lim, Kyung Hyun Choi
Immunosensors are used to detect the presence of certain bio-reagents mostly targeted at the diagnosis of a condition or a disease. Here, a general purpose electrical immunosensor has been fabricated for the quantitative detection of multiple bio-reagents through the formation of an antibody-antigen pair. The sensors were fabricated using all printing approaches. 2D transition metal dichalcogenide (TMDC) MoS2 thin film was deposited using Electrohydrodynamic atomization (EHDA) on top of an interdigitated transducer (IDT) electrode fabricated by reverse offset printing...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724795/alx-receptor-ligands-define-a-biochemical-endotype-for-severe-asthma
#6
Isabell Ricklefs, Ioanna Barkas, Melody G Duvall, Manuela Cernadas, Nicole L Grossman, Elliot Israel, Eugene R Bleecker, Mario Castro, Serpil C Erzurum, John V Fahy, Benjamin M Gaston, Loren C Denlinger, David T Mauger, Sally E Wenzel, Suzy A Comhair, Andrea M Coverstone, Merritt L Fajt, Annette T Hastie, Mats W Johansson, Michael C Peters, Brenda R Phillips, Bruce D Levy
BACKGROUND: In health, inflammation resolution is an active process governed by specialized proresolving mediators and receptors. ALX/FPR2 receptors (ALX) are targeted by both proresolving and proinflammatory ligands for opposing signaling events, suggesting pivotal roles for ALX in the fate of inflammatory responses. Here, we determined if ALX expression and ligands were linked to severe asthma (SA). METHODS: ALX expression and levels of proresolving ligands (lipoxin A4 [LXA4], 15-epi-LXA4, and annexin A1 [ANXA1]), and a proinflammatory ligand (serum amyloid A [SAA]) were measured in bronchoscopy samples collected in Severe Asthma Research Program-3 (SA [n = 69], non-SA [NSA, n = 51] or healthy donors [HDs, n = 47])...
July 20, 2017: JCI Insight
https://www.readbyqxmd.com/read/28720137/cortical-thickness-in-the-intertrochanteric-region-may-be-relevant-to-hip-fracture-type
#7
Huafeng Zhuang, Yizhong Li, Jinkuang Lin, Donglu Cai, Siqing Cai, Lisheng Yan, Xuedong Yao
BACKGROUND: This study assessed the differences in femoral geometry and bone mineral density between femoral neck fragility fractures and trochanteric fractures. METHODS: One hundred and seventeen patients were divided into femoral neck and trochanteric fracture groups. There were 69 patients with femoral neck fractures, 20 men and 49 women with an average age of 75.1 ± 9.6 years and an average body mass index (BMI) value of 21.6 ± 4.1 kg/m(2). The trochanteric group consisted of 48 patients, 16 men and 32 women with an average age of 78...
July 18, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28717369/association-of-irritable-bowel-syndrome-and-sleep-apnea-in-patients-referred-to-sleep-laboratory
#8
Farzin Ghiasi, Babak Amra, Vahid Sebghatollahi, Fatemeh Azimian
BACKGROUND: Irritable bowel syndrome (IBS) is assumed as one of the most frequent gastrointestinal disorders, which decreases the patient's quality of life. IBS pathogenesis, however, is not clearly defined. It seems that sleep apnea induces or escalates IBS clinical symptoms. This study aims at evaluating of IBS prevalence in patients, who are afflicted or are not afflicted with sleep apnea. MATERIALS AND METHODS: This was a case-control study, which was implemented in a sleep laboratory located in Isfahan, Iran...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28716527/identification-of-a-synergistic-combination-of-smac-mimetic-and-bortezomib-to-trigger-cell-death-in-b-cell-non-hodgkin-lymphoma-cells
#9
Irfan Ahmed Bhatti, Behnaz Ahangarian Abhari, Simone Fulda
Recently, copy number gains and increased expression levels of cIAP1 and cIAP2 have been reported in B-cell non-Hodgkin lymphomas (NHL). Therefore, we investigated the therapeutic potential of the Smac mimetic BV6 that antagonizes cIAP1/2 and XIAP. Here, we discover that subtoxic concentrations of BV6 prime B-cell NHL cells to proteasome inhibitor Bortezomib-induced cell death. Synergistic induction of cell death by BV6 and Bortezomib is confirmed by calculation of combination index in different cell lines, emphasizing the broader relevance of this combination...
July 14, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28639152/influence-of-muscle-groups-activation-on-proximal-femoral-growth-tendency
#10
Priti Yadav, Sandra J Shefelbine, Eva Pontén, Elena M Gutierrez-Farewik
Muscle and joint contact force influence stresses at the proximal growth plate of the femur and thus bone growth, affecting the neck shaft angle (NSA) and femoral anteversion (FA). This study aims to illustrate how different muscle groups' activation during gait affects NSA and FA development in able-bodied children. Subject-specific femur models were developed for three able-bodied children (ages 6, 7, and 11 years) using magnetic resonance images. Contributions of different muscle groups-hip flexors, hip extensors, hip adductors, hip abductors, and knee extensors-to overall hip contact force were computed...
June 22, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28607651/assessment-of-the-diagnostic-accuracy-of-double-inversion-recovery-sequence-compared-with-flair-and-t2w_tse-in-detection-of-cerebral-multiple-sclerosis-lesions
#11
Zahra Abidi, Fariborz Faeghi, Zahra Mardanshahi, Hasan Mortazavi
BACKGROUND: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. MRI has an important role in early diagnosis of MS within diagnostic criteria. AIM: To determine the diagnostic value of the double inversion recovery (DIR) sequence in detection of brain MS lesions. METHODS: In this cross-sectional study, 55 patients were admitted to the MRI department in Vali-E-Asr Hospital in Qaemshahr, Iran, from May 2016 to February 2016...
April 2017: Electronic Physician
https://www.readbyqxmd.com/read/28589290/validation-of-a-single-summary-score-for-the-prolapse-incontinence-sexual-questionnaire-iuga-revised-pisq-ir
#12
Melissa L Constantine, Rachel N Pauls, Rebecca R Rogers, Todd H Rockwood
INTRODUCTION AND HYPOTHESIS: The Prolapse/Incontinence Sexual Questionnaire-International Urogynecology Association (IUGA) Revised (PISQ-IR) measures sexual function in women with pelvic floor disorders (PFDs) yet is unwieldy, with six individual subscale scores for sexually active women and four for women who are not. We hypothesized that a valid and responsive summary score could be created for the PISQ-IR. METHODS: Item response data from participating women who completed a revised version of the PISQ-IR at three clinical sites were used to generate item weights using a magnitude estimation (ME) and Q-sort (Q) approaches...
June 6, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28585457/effect-of-geometric-parameters-in-the-design-of-customized-hip-implants
#13
Mangesh Dharme, Abhaykumar Kuthe
In this paper, the effects of geometric parameters on the development of stress in custom cementless hip implant have been studied. Taguchi methods and analysis of variance (ANOVA) were used to find out which geometric parameters are statistically significant for the maximum von Mises stresses in the hip implant. The multiple regression analysis was also performed, to replace the FE solver and accurately and quickly predict the stress values for new patients. Three parameters horizontal offset (HO), vertical offset and neck shaft angle (NSA), with three levels have been selected...
June 6, 2017: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/28560796/postoperative-evaluation-of-reduction-loss-in-proximal-humeral-fractures-a-comparison-of-plain-radiographs-and-computed-tomography
#14
Xiao-Yang Jia, Yan-Xi Chen, Min-Fei Qiang, Kun Zhang, Hao-Bo Li, Yu-Chen Jiang, Yi-Jie Zhang
OBJECTIVE: To compare postoperative CT images with plain radiographs for measuring prognostic factors of reduction loss of fractures of the proximal part of the humerus. METHODS: A total of 65 patients who sustained fractures of the proximal humerus treated with locking plates from June 2012 to October 2015 were retrospectively analyzed. There were 24 men and 41 women, with a mean age of 60.0 years (range, 22-76 years). According to the Neer classification system of proximal humeral fracture, there were 26 two-part, 27 three-part and 12 four-part fractures of the proximal part of the humerus, and all fractures were treated with open reduction and internal fixation (ORIF) using locked plating...
May 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28529944/optimization-of-time-for-neural-stem-cells-transplantation-for-brain-stroke-in-rats
#15
Seyyed Mohyeddin Ziaee, Parisa Tabeshmehr, Khawaja Husnain Haider, Majidreza Farrokhi, Abdolhamid Shariat, Atena Amiri, Seyed Mojtaba Hosseini
BACKGROUND: Despite encouraging data in terms of neurological outcome, stem cell based therapy for ischemic stroke in experimental models and human patients is still hampered by multiple as yet un-optimized variables, i.e., time of intervention, that significantly influence the prognosis. The aim of the present study was to delineate the optimum time for neural stem cells (NSCs) transplantation after ischemic stroke. METHODS: The NSCs were isolated from 14 days embryo rat ganglion eminence and were cultured in NSA medium (neurobasal medium, 2% B27, 1% N2, bFGF 10 ng/mL, EGF 20 ng/mL and 1% pen/strep)...
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28500940/efficient-catalytic-hydration-of-cyanamides-in-aqueous-medium-and-in-the-presence-of-naringin-sulfuric-acid-or-green-synthesized-silver-nanoparticles-by-using-gongronema-latifolium-leaf-extract
#16
Zahra Issaabadi, Mahmoud Nasrollahzadeh, S Mohammad Sajadi
In this paper, a novel, efficient and green method for the preparation of Naringin sulfuric acid (NSA) as a Brønsted acid organocatalyst and silver nanoparticles (Ag NPs) by using Gongronema latifolium leaf extract as a reducing and stabilizing agent is introduced. The catalysts were characterized using the powder XRD, SEM, EDS, TEM, UV-Vis and FT-IR spectroscopy. Afterward, the catalytic activity of synthesized NSA and Ag NPs were investigated for the synthesis of N-monosubstituted ureas via the hydration of cyanamides in aqueous medium...
October 1, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28499398/biomechanical-evaluation-of-a-novel-dualplate-fixation-method-for-proximal-humeral-fractures-without-medial-support
#17
Yu He, Yaoshen Zhang, Yan Wang, Dongsheng Zhou, Fu Wang
BACKGROUND: Comminuted fractures of the proximal humerus are generally treated with the locking plate system, and clinical results are satisfactory. However, unstable support of the medial column results in varus malunion and screw perforation. We designed a novel medial anatomical locking plate (MLP) to directly support the medial column. Theoretically, the combined application of locking plate and MLP (LPMP) would directly provide strong dual-column stability. We hypothesized that the LPMP could provide greater construct stability than the locking plate alone (LP), locking plate combined with a fibular graft (LPSG), and locking plate combined with a distal radius plate (LPDP)...
May 12, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28464594/-analysis-on-the-performance-evaluation-of-the-global-fund-malaria-programme-in-china-from-2003-to-2013
#18
Q F Zhang, R B Wang, B Zheng, Z G Xia, S S Zhou
Objective: To analyze the performance of the 5 Global Fund Malaria Programmes in China from 2003 to 2013. Methods: All of the proposals, summaries, progress reports, survey reports, Monitoring& Evaluation reports, and performance rating reports of the 5 Global Fund Malaria Programmes in China and the epidemic data of program areas were collected for statistical analysis from 2012 to 2014. Symposiums were held with relevant experts from national and provincial Centers for Disease Control and Prevention, program managers and staffs from national and provincial Global Fund Malaria Programme offices...
May 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28461299/th-2-signature-in-chronic-airway-diseases-towards-the-extinction-of-asthma-copd-overlap-syndrome
#19
Borja G Cosío, Luis Pérez de Llano, Antolin Lopez Viña, Alfons Torrego, Jose Luis Lopez-Campos, Joan B Soriano, Eva Martinez Moragon, Jose Luis Izquierdo, Irina Bobolea, Javier Callejas, Vicente Plaza, Marc Miravitlles, Juan Jose Soler-Catalunya
We aimed to describe the differences and similarities between patients with chronic obstructive airway disease classified on the basis of classical diagnostic labels (asthma, chronic obstructive pulmonary disease (COPD), or asthma-COPD overlap (ACOS)) or according to the underlying inflammatory pattern (Th-2 signature, either Th-2-high or Th-2-low).We performed a cross-sectional study of patients aged ≥40 years and with a post-bronchodilator forced expiratory volume in 1 s to forced vital capacity ratio ≤0...
May 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28445878/differential-allelic-expression-of-htr1b-in-suicide-victims-genetic-and-epigenetic-effect-of-the-cis-acting-variants
#20
Ali Bani-Fatemi, Aaron Howe, Clement Zai, James L Kennedy, John Vincent, John Strauss, Albert Wong, Vincenzo De Luca
OBJECTIVES: In the present study, we tested the allelic imbalance of the C861G single nucleotide polymorphism (SNP) of HTR1B in the frontal cortex of suicide victims. METHODS: The study was conducted using 3 sets of samples. First, C861G allele-specific mRNA levels in the frontal cortex were compared between suicide (n = 13) and nonsuicide controls (n = 13) from the Stanley Medical Research postmortem brain collection. Second, we tested common variants in the HTR1B promoter for linkage disequilibrium (LD) with the C861G variant in an unrelated sample of suicide attempters (SA; n = 38) and non-SA (NSA; n = 42)...
2016: Neuropsychobiology
keyword
keyword
47365
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"