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https://www.readbyqxmd.com/read/29887497/nasal-septal-abscess-caused-by-anaerobic-bacteria-of-oral-flora
#1
Yukiyoshi Hyo, Hisaki Fukushima, Tamotsu Harada, Hirotaka Hara
Although nasal septal abscess (NSA) was formerly common, it has become rare since the development of antibiotics. NSA, if left untreated, can lead to intracranial complications such as meningitis and eventually result in saddle-nose deformity. NSA often occurs after injury, and indigenous skin bacteria such as Staphylococcus aureus are frequently detected. We treated a patient who had injured the upper alveolus in a fall on the stairs and developed NSA two weeks later. Anaerobic bacteria, including Veillonella parvula and Peptostreptococcus sp...
June 7, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29882917/label-free-detection-of-salivary-pepsin-using-gold-nanoparticle-polypyrrole-nanocoral-modified-screen-printed-electrode
#2
Doyeon Lee, Young Ju Lee, Young-Gyu Eun, Gi-Ja Lee
Detection of salivary pepsin has been given attention as a new diagnostic tool for laryngopharyngeal reflux (LPR) disease, because saliva collection is non-invasive and relatively comfortable. In this study, we prepared polypyrrole nanocorals (PPNCs) on a screen-printed carbon electrode (SPCE) by a soft template synthesis method, using β-naphthalenesulfonic acid (NSA) (for short, PPNCs/SPCE). Gold nanoparticles (GNPs) were then decorated on PPNCs/SPCE by electrodeposition (for short, GNP/PPNCs/SPCE)...
May 24, 2018: Sensors
https://www.readbyqxmd.com/read/29808833/mnmoo4-nanosheet-array-an-efficient-electrocatalyst-for-hydrogen-evolution-reaction-with-enhanced-activity-over-a-wide-ph-range
#3
Lulu Wen, Yiqiang Sun, Tao Zhang, Yu Bai, Xinyang Li, Xianjun Lyu, Weiping Cai, Yue Li
We report the preparation of MnMoO4 nanosheet array on Nickel Foam (MnMoO4 NSA/NF) as an excellent 3D HER electrocatalyst with good catalytic performance applied under basic, acidic and neutral conditions. In 0.5 M H2SO4, this MnMoO4 NSA/NF electrode needs an overpotential of 89 mV to drive current densities of 10 mA cm-2, to achieve the same current density, it demands overpotentials of 105 mV in 1.0 M KOH, 161 mV in 1.0 M PBS (pH=7), respectively. After continuous CV scanning for 1000 cycles under different pH conditions, it also demonstrates an excellent stability with ignorable activity decrease...
May 29, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29801900/practical-issues-in-measuring-autoantibodies-to-neuronal-cell-surface-antigens-in-autoimmune-neurological-disorders-190-cases
#4
Juntaro Kaneko, Naomi Kanazawa, Naomi Tominaga, Atsushi Kaneko, Hiroki Suga, Ryo Usui, Daisuke Ishima, Eiji Kitamura, Tsugio Akutsu, Koji Yoshida, Kazutoshi Nishiyama, Takahiro Iizuka
OBJECTIVES: To address practical issues in measuring autoantibodies to neuronal cell-surface antigens (NSAs) in various autoimmune neurological disorders (ANDs). METHODS: We retrospectively reviewed the clinical information of 221 patients with clinically suspected ANDs who underwent antibody testing for NSAs between January 2007 and September 2017. 31 were excluded. In 190 patients, antibody-detection rate (ADR) and antibody-phenotype association were assessed...
July 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29790356/-non-opioid-analgesics
#5
Jitka Fricová
Non-opioid analgesics are commonly used to treat mild and moderate acute and chronic pain. They can be used as monotherapy; however, they have greater efficacy in combination with weak and strong opioids. Unlike opioids, long-term use of non-steroidal anti-inflammatory drugs does not lead to physical dependence. One of the main disadvantages of the NSA is the risk of gastrointestinal side effects, especially bleeding into the digestive tract. This is increased especially in ulcerative disease and in higher doses, but also in the elderly (over 65 years), also with concomitant administration of corticosteroids, anticoagulants or other NSAIDs...
2018: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29780366/biological-control-of-mango-dieback-disease-caused-by-lasiodiplodia-theobromae-using-streptomycete-and-non-streptomycete-actinobacteria-in-the-united-arab-emirates
#6
Fatima H Kamil, Esam E Saeed, Khaled A El-Tarabily, Synan F AbuQamar
Dieback caused by the fungus Lasiodiplodia theobromae is an important disease on mango plantations in the United Arab Emirates (UAE). In this study, 53 actinobacterial isolates were obtained from mango rhizosphere soil in the UAE, of which 35 (66%) were classified as streptomycetes (SA) and 18 (34%) as non-streptomycetes (NSA). Among these isolates, 19 (12 SA and 7 NSA) showed antagonistic activities against L. theobromae associated with either the production of diffusible antifungal metabolites, extracellular cell-wall-degrading enzymes (CWDEs), or both...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29748099/scholarly-impact-of-student-participation-in-radiation-oncology-research
#7
Munizay Paracha, Kristine N Kim, Muhammad M Qureshi, Aishwarya Shah, Ankit Agarwal, Teviah Sachs, Suzanne Sarfaty, Ariel E Hirsch
PURPOSE: To evaluate the rate of non-doctoral student authors publishing in an academic journal over time and to analyze the effects student authors have on the scholarly impact of corresponding authors (CAs) by comparing their respective H-index (Hi ). METHODS AND MATERIALS: A database was created of authors who published articles in the International Journal of Radiation Oncology, Biology, Physics in 2006, 2010, and 2014 that included CA, degree, and student author designations...
March 6, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29732417/perioperative-care-for-lumbar-microdiscectomy-a-survey-of-australasian-neurosurgeons
#8
Christopher D Daly, Kai Zheong Lim, Peter Ghosh, Tony Goldschlager
Background: Lumbar microdiscectomy is the most commonly performed spine surgery procedure. Over time it has evolved to a minimally invasive procedure. Traditionally patients were advised to restrict activity following lumbar spine surgery. However, post-operative instructions are heterogeneous. The purpose of this report is to assess, by survey, the perioperative care practices of Australasian neurosurgeons in the minimally invasive era. Methods: A survey was conducted by email invitation sent to all full members of the Neurosurgical Society of Australasia (NSA)...
March 2018: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29703255/fate-of-stable-hips-after-prophylactic-femoral-varization-osteotomy-in-patients-with-cerebral-palsy
#9
Ki Hyuk Sung, Soon-Sun Kwon, Chin Youb Chung, Kyoung Min Lee, Jaeyoung Kim, Seung Yeol Lee, Moon Seok Park
BACKGROUND: Concurrent prophylactic femoral varization osteotomy (FVO) for stable hips has been performed in patients with cerebral palsy (CP) undergoing hip reconstructive surgery for the contralateral displaced hip. However, there is currently a lack of studies investigating the outcome after the prophylactic FVO in stable hip. This study investigated the outcomes after FVO in stable hips with CP and influencing factors. In addition, this study compared the outcomes with those after hip reconstructive surgery in the contralateral displaced hip...
April 27, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29685545/improvement-of-reliability-of-diffusion-tensor-metrics-in-thigh-skeletal-muscles
#10
Sarah Keller, Avneesh Chhabra, Shaheen Ahmed, Anne C Kim, Jonathan M Chia, Jin Yamamura, Zhiyue J Wang
OBJECTIVE: Quantitative diffusion tensor imaging (DTI) of skeletal muscles is challenging due to the bias in DTI metrics, such as fractional anisotropy (FA) and mean diffusivity (MD), related to insufficient signal-to-noise ratio (SNR). This study compares the bias of DTI metrics in skeletal muscles via pixel-based and region-of-interest (ROI)-based analysis. METHODS: DTI of the thigh muscles was conducted on a 3.0-T system in N = 11 volunteers using a fat-suppressed single-shot spin-echo echo planar imaging (SS SE-EPI) sequence with eight repetitions (number of signal averages (NSA) = 4 or 8 for each repeat)...
May 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29675742/specific-c%C3%AE-c-bond-cleavage-of-%C3%AE-carbon-centered-radical-peptides-produced-by-matrix-assisted-laser-desorption-ionization-mass-spectrometry
#11
Keishiro Nagoshi, Mariko Yamakoshi, Kenya Sakamoto, Mitsuo Takayama
Radical-driven dissociation (RDD) of hydrogen-deficient peptide ions [M - H + H]·+ has been examined using matrix-assisted laser dissociation/ionization in-source decay mass spectrometry (MALDI-ISD MS) with the hydrogen-abstracting matrices 4-nitro-1-naphthol (4,1-NNL) and 5-nitrosalicylic acid (5-NSA). The preferential fragment ions observed in the ISD spectra include N-terminal [a] + ions and C-terminal [x]+ , [y + 2]+ , and [w]+ ions which imply that β-carbon (Cβ)-centered radical peptide ions [M - Hβ + H]·+ are predominantly produced in MALDI conditions...
April 19, 2018: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/29664885/the-effect-of-hip-positioning-on-the-projected-femoral-neck-shaft-angle-a-modeling-study
#12
Abhiram R Bhashyam, Edward K Rodriguez, Paul Appleton, John J Wixted
OBJECTIVES: The femoral neck-shaft angle (NSA) is used to restore normal hip geometry during hip fracture repair. Femoral rotation is known to affect NSA measurement, but the effect of hip flexion-extension is unknown. The goals of this study were to determine and test mathematical models of the relationship between hip flexion-extension, femoral rotation and NSA. We hypothesized that hip flexion-extension and femoral rotation would result in NSA measurement error. METHODS: Two mathematical models were developed to predict NSA in varying degrees of hip flexion-extension and femoral rotation...
April 3, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29653242/effect-of-combined-flexion-and-external-rotation-on-measurements-of-the-proximal-femur-from-anteroposterior-pelvic-radiographs
#13
J D O'Connor, M Rutherford, J C Hill, D E Beverland, N J Dunne, A B Lennon
INTRODUCTION: Fixed flexion and external rotation contractures are common in patients with hip osteoarthritis and, in particular, before total hip replacement (THR). We aimed to answer the following question: how does combined flexion and external rotation of the femur influence the radiographic assessment of (1) femoral offset (FO) (2) neck-shaft angle (NSA) and (3) distance (parallel to the femoral axis) from greater trochanter to femoral head center (GT-FHC)? HYPOTHESIS: Combined flexion and external rotation impact the accuracy of two-dimensional (2D) proximal femur measurements...
April 10, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29650557/sputum-proteomics-and-airway-cell-transcripts-of-current-and-ex-smokers-with-severe-asthma-in-u-biopred-an-exploratory-analysis
#14
Kentaro Takahashi, Stelios Pavlidis, Francois Ng Kee Kwong, Uruj Hoda, Christos Rossios, Kai Sun, Matthew Loza, Fred Baribaud, Pascal Chanez, Steve J Fowler, Ildiko Horvath, Paolo Montuschi, Florian Singer, Jacek Musial, Barbro Dahlen, Sven-Eric Dahlen, Norbert Krug, Thomas Sandstrom, Dominic E Shaw, Rene Lutter, Per Bakke, Louise J Fleming, Peter H Howarth, Massimo Caruso, Ana R Sousa, Julie Corfield, Charles Auffray, Bertrand De Meulder, Diane Lefaudeux, Ratko Djukanovic, Peter J Sterk, Yike Guo, Ian M Adcock, Kian Fan Chung
Severe asthma patients with a significant smoking history have airflow obstruction with reported neutrophilia. We hypothesise that multi-omic analysis will enable the definition of smoking and ex-smoking severe asthma molecular phenotypes.The U-BIOPRED cohort of severe asthma patients, containing current-smokers (CSA), ex-smokers (ESA), nonsmokers and healthy nonsmokers was examined. Blood and sputum cell counts, fractional exhaled nitric oxide and spirometry were obtained. Exploratory proteomic analysis of sputum supernatants and transcriptomic analysis of bronchial brushings, biopsies and sputum cells was performed...
May 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29628403/spanish-validation-of-the-negative-symptom-assessment-16-nsa-16-in-patients-with-schizophrenia
#15
Leticia Garcia-Alvarez, María Paz Garcia-Portilla, Pilar Alejandra Saiz, Eduardo Fonseca-Pedrero, María Teresa Bobes-Bascaran, Jesús Gomar, José Muñiz, Julio Bobes
INTRODUCTION: Negative symptoms are prevalent in schizophrenia and associated with a poorer outcome. Validated newer psychometric instruments could contribute to better assessment and improved treatment of negative symptoms. The Negative Symptom Assessment-16 (NSA-16) has been shown to have strong psychometric properties, but there is a need for validation in non-English languages. This study aimed to examine the psychometric properties of a Spanish version of the NSA-16 (Sp-NSA-16). MATERIAL AND METHOD: Observational, cross-sectional validation study in a sample of 123 outpatients with schizophrenia...
April 5, 2018: Revista de Psiquiatrí́a y Salud Mental
https://www.readbyqxmd.com/read/29614353/necrosulfonamide-attenuates-spinal-cord-injury-via-necroptosis-inhibition
#16
Yongxiang Wang, Jingcheng Wang, Hua Wang, Xinmin Feng, Yuping Tao, Jiandong Yang, Jun Cai
OBJECTIVE: Spinal cord injury (SCI) is a serious trauma without efficient treatment currently. Necroptosis can be blocked post injury by special inhibitors. This study is to investigate the effects, mechanism, and potential benefit of necrosulfonamide (NSA) for SCI therapy. METHODS: Pathologic condition was detected using hematoxylin-eosin staining on injured spinal cord and other major organs. Necroptosis-related factors-RIP1, RIP3, and MLKL-were detected using Western blot...
June 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29595284/-treat-to-target-in-gouty-arthritis
#17
Karel Pavelka
Gout is a crystal-induced, metabolically determined inflammatory rheumatic disease with increasing prevalence. In clinical practice, gout causes frequent diagnostic as well as therapeutic problems. The golden diagnostic standard is crystalographic analysis and evidence of monosodium urate crystals in the polarization microscope; if this is not available, the diagnosis can be established through a combination of clinical, laboratory and imaging techniques. The acute gouty attack must be treated by quick administration of anti-inflammatory medicines, with available alternatives being nonsteroidal antirheumatic drugs (NSA), colchicine and glucocorticoids...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29595274/-chronic-pain-therapy-in-inflammatory-rheumatic-diseases
#18
David Suchý, Jan Lejčko
Chronic pain is a common health problem related to most of inflammatory rheumatic disorders. It is pain that has persisted for at least 3 month and cannot be fully relieved by standard pain medication. 40-60 % of patients do not have adequate relief of their pain. Paramount in the management of chronic pain patients is assessment of the pain and its impact on physical and psychosocial functioning. Multidisciplinary and multimodal approach is of vital importance. Non-steroidal anti-rheumatic drugs (NSA) have been used mainly due to their strong analgesic effect, especially in the treatment of acute pain as well as their anti-inflammatory effect in the treatment of chronic i pain...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29567105/proximal-and-distal-alignment-of-normal-canine-femurs-a-morphometric-analysis
#19
Mehmet Erkut Kara, Figen Sevil-Kilimci, Ömer Gürkan Dilek, Vedat Onar
Many researchers are interested in femoral conformation because most orthopaedic problems of the long bones occur in the femur and its joints. The neck-shaft (NSA) and the anteversion (AVA) angles are good predictors for understanding the orientation of the proximal end of the femur. The varus (aLDFA) and procurvatum (CDFA) angles have also been used to understand the orientation of the distal end of the femur. The purposes of this study were to investigate the relationship between the proximal and distal angles of the femur and to compare the distal femoral angles in male and female dogs in order to investigate the sexual dimorphism...
May 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29564500/high-throughput-genotyping-by-sequencing-facilitates-molecular-tagging-of-a-novel-rust-resistance-gene-r-15-in-sunflower-helianthus-annuus-l
#20
G J Ma, Q J Song, S G Markell, L L Qi
A novel rust resistance gene, R 15 , derived from the cultivated sunflower HA-R8 was assigned to linkage group 8 of the sunflower genome using a genotyping-by-sequencing approach. SNP markers closely linked to R 15 were identified, facilitating marker-assisted selection of resistance genes. The rust virulence gene is co-evolving with the resistance gene in sunflower, leading to the emergence of new physiologic pathotypes. This presents a continuous threat to the sunflower crop necessitating the development of resistant sunflower hybrids providing a more efficient, durable, and environmentally friendly host plant resistance...
March 21, 2018: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
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