keyword
MENU ▼
Read by QxMD icon Read
search

reflective function

keyword
https://www.readbyqxmd.com/read/28550101/a-novel-experimental-rat-model-of-peripheral-nerve-scarring-reliably-mimicking-post-surgical-complications-and-recurring-adhesions
#1
Angela Lemke, Carina Penzenstadler, James Ferguson, Dominika Lidinsky, Rudolf Hopf, Monika Bradl, Heinz Redl, Susanne Wolbank, Thomas Hausner
Inflammation, fibrosis and perineural adhesions with the surrounding tissue are common pathological processes following nerve injury and surgical interventions on peripheral nerves in human patients. Furthermore, these signs can reoccur following external neurolysis, currently the most common surgical treatment, thus leading to renewed nerve function impairment and chronic pain. To enable a successful evaluation of new therapeutic approaches, it is crucial to use a reproducible animal model that mimics the main clinical symptoms occurring in human patients...
May 26, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28549798/whole-brain-connectivity-dynamics-reflect-both-task-specific-and-individual-specific-modulation-a-multitask-study
#2
REVIEW
Hua Xie, Vince Calhoun, Javier Gonzalez-Castillo, Eswar Damaraju, Robyn Miller, Peter Bandettini, Sunanda Mitra
Functional connectivity (FC) has been widely used to study the functional organization of temporally correlated and spatially distributed brain regions. Recent studies of FC dynamics, quantified by windowed correlations, provide new insights to analyze dynamic, context-dependent reconfiguration of brain networks. A set of reoccurring whole-brain connectivity patterns at rest, referred to as FC states, have been identified, hypothetically reflecting underlying cognitive processes or mental states. We posit that the mean FC information for a given subject represents a significant contribution to the group-level FC dynamics...
May 23, 2017: NeuroImage
https://www.readbyqxmd.com/read/28549648/characterization-of-long-term-gait-deficits-in-mouse-dmcao-using-the-catwalk-system
#3
E Caballero-Garrido, J C Pena-Philippides, Z Galochkina, E Erhardt, T Roitbak
Evaluation of functional outcome is widely used across species to assess the recovery process following various pathological conditions, including spinal cord injury, musculo-skeletal injury, mithochondrial disease, neuropathic cancer, Huntington's disease, chronic pain, cortical lesion, and olivocerebellar degeneration among others. The Stroke Therapy Academic Industry Roundtable (STAIR) recommends multiple endpoints for behavioral studies in pre-clinical stroke research, to demonstrate their clinical relevance...
May 23, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28549448/statistical-permutation-based-artery-mapping-spam-a-novel-approach-to-evaluate-imaging-signals-in-the-vessel-wall
#4
Robert Seifert, Aaron Scherzinger, Friedemann Kiefer, Sven Hermann, Xiaoyi Jiang, Michael A Schäfers
BACKGROUND: Cardiovascular diseases are the leading cause of death worldwide. A prominent cause of cardiovascular events is atherosclerosis, a chronic inflammation of the arterial wall that leads to the formation of so called atherosclerotic plaques. There is a strong clinical need to develop new, non-invasive vascular imaging techniques in order to identify high-risk plaques, which might escape detection using conventional methods based on the assessment of the luminal narrowing. In this context, molecular imaging strategies based on fluorescent tracers and fluorescence reflectance imaging (FRI) seem well suited to assess molecular and cellular activity...
May 26, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28549279/control-adjustments-in-speaking-electrophysiology-of-the-gratton-effect-in-picture-naming
#5
Natalia Shitova, Ardi Roelofs, Herbert Schriefers, Marcel Bastiaansen, Jan-Mathijs Schoffelen
Accumulating evidence suggests that spoken word production requires different amounts of top-down control depending on the prevailing circumstances. For example, during Stroop-like tasks, the interference in response time (RT) is typically larger following congruent trials than following incongruent trials. This effect is called the Gratton effect, and has been taken to reflect top-down control adjustments based on the previous trial type. Such control adjustments have been studied extensively in Stroop and Eriksen flanker tasks (mostly using manual responses), but not in the picture-word interference (PWI) task, which is a workhorse of language production research...
April 29, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28548461/attending-learning-and-socioeconomic-disadvantage-developmental-cognitive-and-social-neuroscience-of-resilience-and-vulnerability
#6
REVIEW
Kylie Schibli, Kyle Wong, Nina Hedayati, Amedeo D'Angiulli
We review current findings associating socioeconomic status (SES), development of neurocognitive functions, and neurobiological pathways. A sizeable interdisciplinary literature was organized through a bifurcated developmental trajectory (BiDeT) framework, an account of the external and internal variables associated with low SES that may lead to difficulties with attention and learning, along with buffers that may protect against negative outcomes. A consistent neurocognitive finding is that low-SES children attend to information nonselectively, and engage in late filtering out of task-irrelevant information...
May 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28548460/internally-generated-hippocampal-sequences-as-a-vantage-point-to-probe-future-oriented-cognition
#7
REVIEW
Giovanni Pezzulo, Caleb Kemere, Matthijs A A van der Meer
Information processing in the rodent hippocampus is fundamentally shaped by internally generated sequences (IGSs), expressed during two different network states: theta sequences, which repeat and reset at the ∼8 Hz theta rhythm associated with active behavior, and punctate sharp wave-ripple (SWR) sequences associated with wakeful rest or slow-wave sleep. A potpourri of diverse functional roles has been proposed for these IGSs, resulting in a fragmented conceptual landscape. Here, we advance a unitary view of IGSs, proposing that they reflect an inferential process that samples a policy from the animal's generative model, supported by hippocampus-specific priors...
May 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28548226/multimodal-connectivity-based-parcellation-reveals-a-shell-core-dichotomy-of-the-human-nucleus-accumbens
#8
Xiaoluan Xia, Lingzhong Fan, Chen Cheng, Simon B Eickhoff, Junjie Chen, Haifang Li, Tianzi Jiang
The subdifferentiation of the nucleus accumbens (NAc) has been extensively studied using neuroanatomy and histochemistry, yielding a well-accepted dichotomic shell/core architecture that reflects dissociable roles, such as in reward and aversion, respectively. However, in vivo parcellation of these structures in humans has been rare, potentially impairing future research into the structural and functional characteristics and alterations of putative NAc subregions. Here, we used three complementary parcellation schemes based on tractography, task-independent functional connectivity, and task-dependent co-activation to investigate the regional differentiation within the NAc...
May 26, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28548172/a-theoretical-study-on-anion-sensing-mechanism-of-multi-phosphonium-triarylboranes-intramolecular-charge-transfer-and-configurational-changes
#9
Haamid R Bhat, Prakash C Jha
The binding selectivity and recognition mechanism of a series of mono-, di- and triphosphonium substituted triarylboranes: (4-(dimesitylboryl)-3,5-dimethylphenyl)phosphonium ([Mes2BAr(P)](+), 1), 1,1'-mesitylboranediylbis(3,5-dimethylphenyl)phosphonium ([MesBAr(P)2](2+), 2) and 1,1',1''-boranetriyltris(3,5-dimethylphenyl)phosphonium ([BAr(P)3](3+), 3) where Ar(P) = 4-(H3P)-2,6-Me2-C6H2, for various anions has been investigated by employing density functional theory (DFT) and time dependent-density functional theory (TD-DFT) methods...
May 26, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28547578/academic-health-center-psychology-representation-to-the-council-of-faculty-and-academic-societies-cfas-of-the-association-of-american-medical-colleges-aamc
#10
Barbara A Cubic, Laura A Shaffer
This paper outlines the perspectives of the two currently appointed representatives of the Association of Psychologists in Academic Health Centers (APAHC) to the Council of Faculty and Academic Societies (CFAS) of the Association of American Medical Colleges (AAMC). The authors focus on why it is important for psychologists, especially those in academic health centers (AHCs), to be part of CFAS. The goal of the paper is to demonstrate how involvement in organizations like the AAMC helps AHC psychologists serve as ambassadors for psychology in AHCs and assists AHC psychologists in staying fluent regarding hot topics within academic medicine...
May 25, 2017: Journal of Clinical Psychology in Medical Settings
https://www.readbyqxmd.com/read/28547320/real-time-noninvasive-monitoring-of-intracranial-fluid-shifts-during-dialysis-using-volumetric-integral-phase-shift-spectroscopy-vips-a-proof-of-concept-study
#11
Chethan P Venkatasubba Rao, Eric M Bershad, Eusebia Calvillo, Nelson Maldonado, Rahul Damani, Sreedhar Mandayam, Jose I Suarez
BACKGROUND: Cerebral edema, which is associated with increased intracranial fluid, is often a complication of many acute neurological conditions. There is currently no accepted method for real-time monitoring of intracranial fluid volume at the bedside. We evaluated a novel noninvasive technique called "Volumetric Integral Phase-shift Spectroscopy (VIPS)" for detecting intracranial fluid shifts during hemodialysis. METHODS: Subjects receiving scheduled hemodialysis for end-stage renal disease and without a history of major neurological conditions were enrolled...
May 25, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28546584/delta-coherence-in-resting-state-eeg-predicts-the-reduction-in-cigarette-craving-after-hypnotic-aversion-suggestions
#12
Xiaoming Li, Ru Ma, Liangjun Pang, Wanwan Lv, Yunlu Xie, Ying Chen, Pengyu Zhang, Jiawen Chen, Qichao Wu, Guanbao Cui, Peng Zhang, Yifeng Zhou, Xiaochu Zhang
Cigarette craving is a key contributor of nicotine addiction. Hypnotic aversion suggestions have been used to help smoking cessation and reduce smoking relapse rates but its neural basis is poorly understood. This study investigated the underlying neural basis of hypnosis treatment for nicotine addiction with resting state Electroencephalograph (EEG) coherence as the measure. The sample consisted of 42 male smokers. Cigarette craving was measured by the Tobacco Craving Questionnaire. The 8-minute resting state EEG was recorded in baseline state and after hypnotic induction in the hypnotic state...
May 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28546304/comparison-of-methods-of-estimating-creatinine-clearance-in-pediatric-patients
#13
Danielle Padgett, Andrew Ostrenga, Lindsey Lepard
PURPOSE: A retrospective study was conducted to compare various methods of measuring serum creatinine (SCr) values for use in pediatric renal function assessments, including a method aligned with a recently implemented national SCr testing standard. METHODS: Demographic, medication-use, and selected laboratory data were collected from the hospital records of a sample of pediatric patients (n = 91) who underwent 12- or 24-hour timed urine collection for determination of creatinine clearance (CLcr) over a 2-year period...
June 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28546080/exosomes-in-hiv-infection-a-review-and-critical-look
#14
REVIEW
Joel Henrique Ellwanger, Tiago Degani Veit, José Artur Bogo Chies
Exosomes are nanovesicles released into the extracellular medium by different cell types. These vesicles carry a variety of protein and RNA cargos, and have a central role in cellular signaling and regulation. A PubMed search using the term "exosomes" finds 67 articles published in 2006. Ten years later, the same search returns approximately 1200 results for 2016 alone. The growing interest in exosomes within the scientific community reflects the different roles exerted by extracellular vesicles in biological systems and diseases...
May 22, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28546010/cognitive-training-as-a-potential-treatment-for-overweight-and-obesity-a-critical-review-of-the-evidence-proposal-for-special-issue-in-appetite-executive-function-training-eating-behaviour
#15
REVIEW
Andrew Jones, Charlotte A Hardman, Natalia Lawrence, Matt Field
The aim of this review is to critically evaluate the effectiveness and candidate mechanisms of action of psychological interventions which aim to either (a) improve the capacity for self-regulatory, reflective processes or (b) reduce the impact of automatic appetitive processes, in an attempt to influence food intake and associated weight-gain. Our aim was to examine three important issues regarding each type of intervention: i) whether the intervention influenced behaviour in the laboratory, ii) whether the intervention influenced behaviour and/or body mass index in the real world, and iii) whether the proposed mechanism of action was supported by evidence...
May 22, 2017: Appetite
https://www.readbyqxmd.com/read/28545894/post-occlusive-reactive-hyperaemia-of-skin-microvasculature-and-foot-complications-in-type-2-diabetes
#16
Sean M Lanting, Alex L Barwick, Stephen M Twigg, Nathan A Johnson, Michael K Baker, Simon K Chiu, Ian D Caterson, Vivienne H Chuter
AIMS: Diabetes-related microvascular disease has been implicated in the development of foot ulceration and amputation. Assessment of microvascular function may be effective in identifying those at risk of diabetic foot complications. We investigated the relationship between active or previous foot complication and post-occlusive reactive hyperaemia (PORH) measured by laser-Doppler fluxmetry (LDF) in people with type 2 diabetes. METHODS: PORH measures were obtained from the hallux apex in 105 people with type 2 diabetes...
May 14, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28545395/characterizing-the-roles-of-changing-population-size-and-selection-on-the-evolution-of-flux-control-in-metabolic-pathways
#17
Alena Orlenko, Peter B Chi, David A Liberles
BACKGROUND: Understanding the genotype-phenotype map is fundamental to our understanding of genomes. Genes do not function independently, but rather as part of networks or pathways. In the case of metabolic pathways, flux through the pathway is an important next layer of biological organization up from the individual gene or protein. Flux control in metabolic pathways, reflecting the importance of mutation to individual enzyme genes, may be evolutionarily variable due to the role of mutation-selection-drift balance...
May 25, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28545115/network-architecture-associated-with-the-highly-specialized-hindlimb-of-frogs
#18
Daniel Andrés Dos Santos, Jéssica Fratani, María Laura Ponssa, Virginia Abdala
Network analyses have been increasingly used in the context of comparative vertebrate morphology. The structural units of the vertebrate body are treated as discrete elements (nodes) of a network, whose interactions at their physical contacts (links) determine the phenotypic modules. Here, we use the network approach to study the organization of the locomotor system underlying the hindlimb of frogs. Nodes correspond to fibrous knots, skeletal and muscular units. Edges encode the ligamentous and monoaxial tendinous connections in addition to joints...
2017: PloS One
https://www.readbyqxmd.com/read/28545040/exploring-the-role-of-white-matter-connectivity-in-cortex-maturation
#19
Cecilia L Friedrichs-Maeder, Alessandra Griffa, Juliane Schneider, Petra Susan Hüppi, Anita Truttmann, Patric Hagmann
The maturation of the cortical gray matter (GM) and white matter (WM) are described as sequential processes following multiple, but distinct rules. However, neither the mechanisms driving brain maturation processes, nor the relationship between GM and WM maturation are well understood. Here we use connectomics and two MRI measures reflecting maturation related changes in cerebral microstructure, namely the Apparent Diffusion Coefficient (ADC) and the T1 relaxation time (T1), to study brain development. We report that the advancement of GM and WM maturation are inter-related and depend on the underlying brain connectivity architecture...
2017: PloS One
https://www.readbyqxmd.com/read/28545013/level-of-functioning-perceived-work-ability-and-work-status-among-psychiatric-patients-with-major-mental-disorders
#20
B Karpov, G Joffe, K Aaltonen, J Suvisaari, I Baryshnikov, P Näätänen, M Koivisto, T Melartin, J Oksanen, K Suominen, M Heikkinen, E Isometsä
BACKGROUND: Major mental disorders are highly disabling conditions that result in substantial socioeconomic burden. Subjective and objective measures of functioning or ability to work, their concordance, or risk factors for them may differ between disorders. METHODS: Self-reported level of functioning, perceived work ability, and current work status were evaluated among psychiatric care patients with schizophrenia or schizoaffective disorder (SSA, n=113), bipolar disorder (BD, n=99), or depressive disorder (DD, n=188) within the Helsinki University Psychiatric Consortium Study...
April 7, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
keyword
keyword
47358
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"