keyword
MENU ▼
Read by QxMD icon Read
search

difficult conversations

keyword
https://www.readbyqxmd.com/read/28534324/-strategies-of-diagnosis-and-treatment-for-peritoneal-metastasis-of-gastric-cancer
#1
Pin Liang, Xiang Hu
Peritoneal metastasis of gastric cancer is the main cause of death in gastric cancer patients. Peritoneal metastasis of gastric cancer is difficult to diagnose in its early stage due to lack of obvious clinical signs and symptoms, and poor treatment outcomes and prognosis are often associated with late stage peritoneal metastasis. Therefore, it is crucial to utilize effective early diagnostic tools and to improve the long-term outcomes and the prognosis of patients with advanced gastric cancer. Recently, systemic chemotherapy and intraperitoneal chemotherapy are the first line therapy, and cytoreductive operation plus abdominal cavity thermochemotherapy may be the best method in the treatment of peritoneal metastasis...
May 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28528215/patients-criteria-determining-difficulty-of-the-laparoscopic-lateral-transperitoneal-adrenalectomy-a-retrospective-cohort-study
#2
Michał Natkaniec, Jadwiga Dworak, Michał Pędziwiatr, Magdalena Pisarska, Piotr Major, Marcin Dembiński, Marek Winiarski, Andrzej Budzyński
BACKGROUND: Identification of patients in whom adrenalectomy may be more difficult, can help in decision making in borderline and doubtful cases. The aim of the study was to determine patients criteria influencing difficulty of laparoscopic lateral transperitoneal adrenalectomy (LTA). MATERIAL AND METHODS: The study enrolled 275 patients who underwent LTA. We analyzed the impact of gender, age, history of previous abdominal surgery, body mass index, risk of anesthesia measured as ASA scale, size, localization (left/right), and histological type of the tumor on parameters reflecting the level of difficulty of the procedure: operative time, intraoperative blood loss, conversion rate and intraoperative complications rate...
May 17, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28527027/a-systematic-review-of-smartphone-applications-for-smoking-cessation
#3
REVIEW
Brianna L Haskins, Donna Lesperance, Patric Gibbons, Edwin D Boudreaux
Tobacco use is the leading cause of preventable disease and death in the USA. However, limited data exists regarding smoking cessation mobile app quality and intervention effectiveness. Innovative and scalable interventions are needed to further alleviate the public health implications of tobacco addiction. The proliferation of the smartphone and the advent of mobile phone health interventions have made treatment more accessible than ever. The purpose of this review was to examine the relation between published scientific literature and available commercial smartphone health apps for smoking cessation to identify the percentage of scientifically supported apps that were commercially available to consumers and to determine how many of the top commercially available apps for smoking cessation were supported by the published scientific literature...
May 19, 2017: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/28522298/%C3%AE-cyclodextrin-induces-the-differentiation-of-resident-cardiac-stem-cells-to-cardiomyocytes-through-autophagy
#4
Xingxing Shi, Wenjing Li, Honghong Liu, Deling Yin, Jing Zhao
Cardiac stem cells (CSCs) have emerged as promising cell candidates to regenerate damaged hearts, because of the potential in differentiating to cardiomyocytes. However, the differentiation is difficult to trigger without inducers. Here we reported that β-cyclodextrin (β-CD) increased the expression of cardiac transcription factors (Nkx2.5 and GATA4), structural proteins (cardiac Troponin T, cTnt), transcriptional enhancer (Mef2c) and induced GATA4 nucleus translocation in adult resident CSCs, thus β-CD could be used to enhance myogenic transition...
May 15, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28520651/laparoscopic-management-of-hepatocellular-carcinoma-a-critical-reappraisal
#5
David Fuks, Luca Aldrighetti, Long R Jiao, Go Wakabayashi, Paolo Limongelli
Following the introduction of the first laparoscopic liver resection, after ∼25 years, a critical reappraisal seems to be warranted. Liver resection represents the first choice for curing early hepatocellular carcinoma (HCC) allowing a curative chance also in selected patients with intermediate stage tumors. The criteria for liver resectability by laparoscopy remains the same for open surgery, which is oncological criteria (absence of extrahepatic tumor location; completely resectable R0 resection), anatomic (resectability of involved segment with its own blood surely and biliary drainage; absence of vascular invasion of portal or hepatic veins) and technical (possibility to leave in place a residual volume ≥40%)...
May 17, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28514179/two-incision-laparoscopic-cholecystectomy-reducing-scars-in-a-simple-way
#6
Rafael Antoniazzi Abaid, Bruno Zilberstein
BACKGROUND: About 20% of the population has cholelithiasis and this is the main abdominal cause of hospitalization in developed countries. Considering that only in the United States about 700,000 cholecystectomies are done each year, it is possible to estimate the importance of the problem for public health. OBJECTIVE: To describe a two-incision laparoscopic cholecystectomy (TILC) technique using only conventional material, without increasing complications or operative time...
May 17, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28512333/hybrid-organic-tandem-solar-cell-comprising-small-molecule-bottom-and-polymer-fullerene-top-subcells-fabricated-by-thin-film-transfer
#7
Yoonseok Ka, Hyejin Hwang, Changsoon Kim
Multilayer structures involving solution-deposited polymer films are difficult to fabricate, not allowing for unrestricted designs of polymer-based optoelectronic devices required for maximizing their performance. Here, we fabricate a hybrid organic tandem solar cell whose top and bottom subcells have polymer:fullerene and small molecules active layers, respectively, by a solvent-free process based on transferring the polymer:fullerene layer from an elastomeric stamp onto a vacuum-deposited bottom subcell. The interface between small-molecule and transferred polymer:fullerene layers is void-free at the nanoscale, allowing for efficient charge transport across the interface...
May 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28511958/selection-of-discriminant-mid-infrared-wavenumbers-by-combining-a-na%C3%A3-ve-bayesian-classifier-and-a-genetic-algorithm-application-to-the-evaluation-of-lignocellulosic-biomass-biodegradation
#8
REVIEW
Abbas Rammal, Eric Perrin, Valeriu Vrabie, Rabih Assaf, Hassan Fenniri
Infrared spectroscopy provides useful information on the molecular compositions of biological systems related to molecular vibrations, overtones, and combinations of fundamental vibrations. Mid-infrared (MIR) spectroscopy is sensitive to organic and mineral components and has attracted growing interest in the development of biomarkers related to intrinsic characteristics of lignocellulose biomass. However, not all spectral information is valuable for biomarker construction or for applying analysis methods such as classification...
May 13, 2017: Mathematical Biosciences
https://www.readbyqxmd.com/read/28506929/inhibition-of-cell-proliferation-and-induction-of-autophagy-by-kdm2b-fbxl10-knockdown-in-gastric-cancer-cells
#9
Erhu Zhao, Chunling Tang, Xiaolan Jiang, Xiong Weng, Xiaoxia Zhong, Dunke Zhang, Jianbing Hou, Feng Wang, Mengying Huang, Hongjuan Cui
Gastric cancer is difficult to cure due to its clinical heterogeneity and the complexity of its molecular mechanisms. KDM2B, a member of the JHDM family, functions as a histone lysine demethylase. However, the role and mechanisms of KDM2B in gastric cancer have not been elucidated. Here, we showed that KDM2B is commonly expressed in gastric cancer cells. The downregulation of KDM2B immediately induces autophagy, followed by the inhibition of proliferation. The compound 3-methyladenine (3-MA), an inhibitor of autophagy, largely rescues autophagy and the inhibition of cell proliferation induced by KDM2B knockdown...
May 12, 2017: Cellular Signalling
https://www.readbyqxmd.com/read/28505697/-the-development-of-palliative-care-hospital-support-teams-hpcts-in-bavaria-from-2011-2015-tasks-acceptance-structure-and-funding
#10
Johanna Anneser, Tamara Thurn, Gian Domenico Borasio
Introduction Palliative care hospital support teams (HPCTs) provide inpatients from all departments palliative medical support. Seriously ill as well as dying patients, who are being treated in facilities that do not have their own palliative care unit, can benefit from these multi-professional teams just as much as patients who do not (yet) need to be admitted to a palliative care unit. At the end of 2015, 53 HPCTs, which were in accordance with the requirements established in the "Program for HPCTs" by the Bavarian Ministry of Health in 2009, had been approved in Bavaria...
May 15, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28495389/clinical-trainees-responses-to-parents-who-question-evidence-based-recommendations
#11
Sydney E Philpott, Holly O Witteman, Katherine M Jones, David S Sonderman, Anne-Sophie Julien, Mary C Politi
OBJECTIVE: We examined clinicians' attitudes, beliefs, and behavioral intentions about discussing evidence and eliciting values when patients question recommendations. METHODS: We randomized trainees to read one of three scenarios about a parent of a one-year-old: 1) overuse (parent requests antibiotics for presumed viral infection); 2) equipoise (tubes for recurrent ear infections); 3) underuse (parent hesitates about vaccination). Participants then answered survey questions...
May 2, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28492241/tuning-the-effective-spin-orbit-coupling-in-molecular-semiconductors
#12
Sam Schott, Erik R McNellis, Christian B Nielsen, Hung-Yang Chen, Shun Watanabe, Hisaaki Tanaka, Iain McCulloch, Kazuo Takimiya, Jairo Sinova, Henning Sirringhaus
The control of spins and spin to charge conversion in organics requires understanding the molecular spin-orbit coupling (SOC), and a means to tune its strength. However, quantifying SOC strengths indirectly through spin relaxation effects has proven difficult due to competing relaxation mechanisms. Here we present a systematic study of the g-tensor shift in molecular semiconductors and link it directly to the SOC strength in a series of high-mobility molecular semiconductors with strong potential for future devices...
May 11, 2017: Nature Communications
https://www.readbyqxmd.com/read/28488050/what-advanced-cancer-patients-with-limited-treatment-options-know-about-clinical-research-a-qualitative-study
#13
Sarah B Garrett, Christopher J Koenig, Laura Trupin, Fay J Hlubocky, Christopher K Daugherty, Anne Reinert, Pamela Munster, Daniel Dohan
PURPOSE: Discussions between oncologists and advanced cancer patients (ACPs) may touch on the complex issue of clinical trial participation. Numerous initiatives have sought to improve the quality of these potentially difficult conversations. However, we have limited data about what ACPs know about clinical research as they enter such discussions as, to date, such research has focused on the period following informed consent. This study examines ACPs' understanding of clinical research in the treatment period before consent...
May 9, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28487263/a-pragmatic-method-for-transforming-clinical-research-data-from-the-research-electronic-data-capture-redcap-to-clinical-data-interchange-standards-consortium-cdisc-study-data-tabulation-model-sdtm-development-and-evaluation-of-redcap2sdtm
#14
Keiichi Yamamoto, Keiko Ota, Ippei Akiya, Ayumi Shintani
The Clinical Data Interchange Standards Consortium (CDISC) Study Data Tabulation Model (SDTM) can be used for new drug application studies as well as secondarily for creating a clinical research data warehouse to leverage clinical research study data across studies conducted within the same disease area. However, currently not all clinical research uses Clinical Data Acquisition Standards Harmonization (CDASH) beginning in the set-up phase of the study. Once already initiated, clinical studies that have not utilized CDASH are difficult to map in the SDTM format...
May 6, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28481290/physicians-religious-topic-avoidance-during-clinical-interactions
#15
Melinda M Villagran, Brenda L MacArthur, Lauren E Lee, Christy J W Ledford, Mollie R Canzona
Religious and spiritual (R/S) conversations at the end-of-life function to help patients and their families find comfort in difficult circumstances. Physicians who feel uncertain about how to discuss topics related to religious beliefs may seek to avoid R/S conversations with their patients. This study utilized a two-group objective structured clinical examination with a standardized patient to explore differences in physicians' use of R/S topic avoidance tactics during a clinical interaction. Results indicated that physicians used more topic avoidance tactics in response to patients' R/S inquiries than patients' R/S disclosures; however, the use of topic avoidance tactics did not eliminate the need to engage in patient-initiated R/S interactions...
May 8, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28479731/simultaneous-determination-of-multiple-ginsenosides-in-panax-ginseng-herbal-medicines-with-one-single-reference-standard
#16
Chunwei Wu, Qingxiao Guan, Shumei Wang, Yueying Rong
BACKGROUND: Root of Panax ginseng C. A. Mey (Renseng in Chinese) is a famous Traditional Chinese Medicine. Ginsenosides are the major bioactive components. However, the shortage and high cost of some ginsenoside reference standards make it is difficult for quality control of P. ginseng. OBJECTIVE: A method, single standard for determination of multicomponents (SSDMC), was developed for the simultaneous determination of nine ginsenosides in P. ginseng (ginsenoside Rg1, Re, Rf, Rg2, Rb1, Rc, Rb2, Rb3, Rd)...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28474219/impact-of-radiofrequency-energy-on-intraoperative-outcomes-of-laparoscopic-colectomy-for-cancer-in-obese-patients
#17
Diletta Cassini, Michelangelo Miccini, Matteo Gregori, Farshad Manoochehri, Gianandrea Baldazzi
Nowadays laparoscopic approach is accepted as a valid alternative to open surgery for the treatment of colorectal cancer. Several studies consider this approach to be safe and feasible also in obese patients, even if dissection in these patients may require a longer operative time and involve higher blood loss. To facilitate laparoscopic approach, more difficult in these patients, several energy sources for laparoscopic dissection and sealing, has been adopted recently. The aim of this study is to investigate the possible intraoperative advantages of radiofrequency energy in terms of blood loss and operative time in obese patients undergoing laparoscopic resection for cancer...
May 4, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28465716/acute-care-surgery-a-means-for-providing-cost-effective-quality-care-for-gallstone-pancreatitis
#18
Patrick B Murphy, Dave Paskar, Richard Hilsden, Jennifer Koichopolos, Tina S Mele
BACKGROUND: Modern practice guidelines recommend index cholecystectomy (IC) for patients admitted with gallstone pancreatitis (GSP). However, this benchmark has been difficult to widely achieve. Previous work has demonstrated that dedicated acute care surgery (ACS) services can facilitate IC. However, the associated financial costs and economic effectiveness of this intervention are unknown and represent potential barriers to ACS adoption. We investigated the impact of an ACS service at two hospitals before and after implementation on cost effectiveness, patient quality-adjusted life years (QALY) and impact on rates of IC...
2017: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/28448386/barriers-to-goal-concordant-care-for-older-patients-with-acute-surgical-illness-communication-patterns-extrinsic-to-decision-aids
#19
Lauren J Taylor, Sara K Johnson, Michael J Nabozny, Jennifer L Tucholka, Nicole M Steffens, Kristine L Kwekkeboom, Karen J Brasel, Toby C Campbell, Margaret L Schwarze
OBJECTIVE: We sought to characterize patterns of communication extrinsic to a decision aid that may impede goal-concordant care. BACKGROUND: Decision aids are designed to facilitate difficult clinical decisions by providing better treatment information. However, these interventions may not be sufficient to effectively reveal patient values and promote preference-aligned decisions for seriously ill, older adults. METHODS: We conducted a secondary analysis of 31 decision-making conversations between surgeons and frail, older inpatients with acute surgical problems at a single tertiary care hospital...
April 26, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28446890/partial-visual-loss-affects-self-reports-of-hearing-abilities-measured-using-a-modified-version-of-the-speech-spatial-and-qualities-of-hearing-questionnaire
#20
Andrew J Kolarik, Rajiv Raman, Brian C J Moore, Silvia Cirstea, Sarika Gopalakrishnan, Shahina Pardhan
We assessed how visually impaired (VI) people perceived their own auditory abilities using an established hearing questionnaire, the Speech, Spatial, and Qualities of Hearing Scale (SSQ), that was adapted to make it relevant and applicable to VI individuals by removing references to visual aspects while retaining the meaning of the original questions. The resulting questionnaire, the SSQvi, assessed perceived hearing ability in diverse situations including the ability to follow conversations with multiple speakers, assessing how far away a vehicle is, and the ability to perceptually segregate simultaneous sounds...
2017: Frontiers in Psychology
keyword
keyword
47349
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"