keyword
MENU ▼
Read by QxMD icon Read
search

Motta

keyword
https://www.readbyqxmd.com/read/28934013/reconciling-conflicting-models-for-global-control-of-cell-cycle-transcription
#1
Chun-Yi Cho, Francis C Motta, Christina M Kelliher, Anastasia Deckard, Steven B Haase
Models for the control of global cell-cycle transcription have advanced from a CDK-APC/C oscillator, a transcription factor (TF) network, to coupled CDK-APC/C and TF networks. Nonetheless, current models were challenged by a recent study that concluded that the cell-cycle transcriptional program is primarily controlled by a CDK-APC/C oscillator in budding yeast. Here we report an analysis of the transcriptome dynamics in cyclin mutant cells that were not queried in the previous study. We find that B-cyclin oscillation is not essential for control of phase-specific transcription...
September 21, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28929113/impact-of-fish-oil-supplementation-and-interruption-of-fructose-ingestion-on-glucose-and-lipid-homeostasis-of-rats-drinking-different-concentrations-of-fructose
#2
Paola M Sulis, Katia Motta, Amanda M Barbosa, Matheus H Besen, Julia S da Silva, Everson A Nunes, Alex Rafacho
Background. Continuous fructose consumption may cause elevation of circulating triacylglycerol. However, how much of this alteration is reverted after the removal of fructose intake is not known. We explored this question and compared the efficacy of this approach with fish oil supplementation. Methods. Male Wistar rats were divided into the following groups: control (C), fructose (F) (water intake with 10% or 30% fructose for 9 weeks), fish oil (FO), and fructose/fish oil (FFO). Fish oil was supplemented only for the last 33 days of fructose ingestion...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28923772/reference-intervals-of-citrated-native-whole-blood-thromboelastography-in-premature-neonates
#3
Mario Motta, Brunetta Guaragni, Elena Pezzotti, Carmen Rodriguez-Perez, Gaetano Chirico
BACKGROUND: Bleeding due to acquired coagulation disorders is a common complication in premature neonates. In this clinical setting, standard coagulation laboratory tests might be unsuitable to investigate the hemostatic function as they reflect the concentration of pro-coagulant proteins but not of anti-coagulant proteins. Thromboelastography (TEG), providing a more complete assessment of hemostasis, may be able to overcome some of these limitations. Unfortunately, experience on the use of TEG in premature neonates is very limited and, in particular in this population, reference ranges of TEG parameters have not been yet evaluated...
September 15, 2017: Early Human Development
https://www.readbyqxmd.com/read/28911955/brief-report-somatic-mutations-and-ancestry-markers-in-hispanic-lung-cancer-patients
#4
Nicholas T Gimbrone, Bhaswati Sarcar, Edna R Gordian, Jason I Rivera, Christian Lopez, Sean J Yoder, Jamie K Teer, Eric A Welsh, Alberto A Chiaporri, Matthew B Schabath, Gary W Reuther, Julie Dutil, Miosotis Garcia, Ronald Ventosilla-Villanueva, Luis Vera-Valdivia, Alejandro Yabar-Berrocal, Rodrigo Motta-Guerrero, Pedro G Santiago-Cardona, Teresita Muñoz-Antonia, W Douglas Cress
INTRODUCTION: To address the lack of genomic data from Hispanic/Latino (H/L) patients with lung cancer, the Latino Lung Cancer Registry was established to collect patient data and biospecimens from these patients. METHODS: This retrospective observational study examined lung cancer tumor samples from 163 H/L patients, and tumor-derived DNA was subjected to targeted-exome sequencing (>1000 genes, including EGFR, KRAS, STK11, and TP53) and ancestry analysis. Mutation frequencies in this H/L cohort were compared with those in a similar cohort of non-Hispanic white (NHW) patients and were correlated with ancestry, sex, smoking status, and tumor histology...
September 11, 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28911258/effect-of-cryopreservation-on-cell-laden-hydrogels-comparison-of-different-cryoprotectants
#5
Nicola Cagol, Walter Bonani, Devid Maniglio, Claudio Migliaresi, Antonella Motta
Cell encapsulation in hydrogels is a technique that offers a variety of applications, ranging from drug delivery to biofabrication of three-dimensional scaffolds. The assembly of cell-laden hydrogel building blocks aims to generate complex biological constructs by manipulating microscale units. An important issue for the clinical implementation of this technique is the long-term storage of a large stock of cell/hydrogel building blocks. In this work, the impact of cryopreservation on the viability and functionality of cells encapsulated in alginate matrices is presented comparing different cryoprotective agents (CPAs)...
September 14, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28902733/131i-whole-body-scan-incidental-uptake-due-to-spermatocele
#6
Domenico Albano, Federica Motta, Carla Baronchelli, Silvia Lucchini, Francesco Bertagna
A 46-year-old man with papillary thyroid cancer post total thyroidectomy was referred for post radioiodine (I) whole-body scan. Whole-body images revealed intense I uptake in the bed thyroid and a focal abnormal uptake in the testicular area. Subsequent SPECT/CT demonstrated that the focal uptake corresponded to the left epididymis, and the pathology report revealed a spermatocele with no immunohistochemical features for thyroid tissue. Many cases of unexpected radioiodine uptake have been reported, and spermatocele could be counted for another possibility of incidental I uptake despite an unclear mechanism...
September 11, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28902296/an-unusual-case-of-bacillary-angiomatosis-in-the-oral-cavity-of-an-aids-patient-who-had-no-concomitant-tegumentary-lesions-case-report-and-review
#7
Walter de Araujo Eyer-Silva, Pedro Eugênio Mendes Arena Soares, Marcelo Costa Velho Mendes de Azevedo, Guilherme Almeida Rosa da Silva, Dario José Hart Pontes Signorini, Rogerio Neves-Motta, Jorge Francisco da Cunha Pinto, Lívia Machado Moura, Rodrigo Panno Basílio-de-Oliveira, Luciana Ferreira de Araujo, Alexsandra Rodrigues de Mendonça Favacho, Elba Regina Sampaio Lemos
Bacillary angiomatosis (BA) is an angioproliferative disease of immunocompromised patients that usually presents as vascular tumors in the skin and subcutaneous tissues. It is caused by chronic infections with either Bartonella henselae or B. quintana. Oral cavity BA is exceedingly rare and even rarer without simultaneous cutaneous disease. We report herein the case of a 51-year-old HIV-infected man who presented severe odynophagia and an eroded lesion on the hard palate that progressed to an oronasal fistula...
August 24, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28902228/comparative-analysis-of-initial-vocalizations-of-preterm-and-full-term-infants-with-and-without-risk-for-development
#8
Isabela de Moraes Fattore, Rejane Maiara Uhde, Luciéle Dias Oliveira, Antônia Motta Roth, Ana Paula Ramos de Souza
Purpose: To compare the evolution of vocalization in preterm and full-term infants, with and without risk for development, analyzing the possible association of sociodemographic, obstetric and psychosocial variables with vocalization. Methods: The study sample consisted of 30 infants, aged 3 months and 1 day to 4 months and 29 days (Phase 1) and 6 months and 1 day to 7 months and 29 days (Phase 2), of both genders, with gestational age <37 weeks (preterm group) and >37 weeks (full-term group)...
August 24, 2017: CoDAS
https://www.readbyqxmd.com/read/28901738/determination-of-the-13c-12c-carbon-isotope-ratio-in-carbonates-and-bicarbonates-by-13c-nmr-spectroscopy
#9
Concetta Pironti, Raffaele Cucciniello, Federica Camin, Agostino Tonon, Oriana Motta, Antonio Proto
This paper is the first study focused on the innovative application of 13C NMR (Nuclear Magnetic Resonance) spectroscopy to determine the bulk 13C/12C carbon isotope ratio, at natural abundance, in inorganic carbonates and bicarbonates. In the past, 13C NMR spectroscopy (irm-13C NMR) was mainly used to measure isotope ratio monitoring with the potential of conducting 13C position-specific isotope analysis of organic molecules with high precision. The reliability of the newly developed methodology for the determination of stable carbon isotope ratio was evaluated in comparison with the method chosen in the past for these measurements, i...
September 13, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28892259/cellulose-production-is-coupled-to-sensing-of-the-pyrimidine-biosynthetic-pathway-via-c-di-gmp-production-by-the-dgcq-protein-of-escherichia-coli
#10
Elio Rossi, Sara Motta, Alessandro Aliverti, Federica Cossu, Louise Gourlay, Pierluigi Mauri, Paolo Landini
Production of cellulose, a stress response-mediated process in enterobacteria, is modulated in Escherichia coli by the activity of the two pyrimidine nucleotide biosynthetic pathways, namely, the de novo biosynthetic pathway, and the salvage pathway, which relies on the environmental availability of pyrimidine nitrogenous bases. We had previously reported that prevalence of the salvage over the de novo pathway triggers cellulose production via synthesis of the second messenger c-di-GMP by the DgcQ (YedQ) diguanylate cyclase...
September 11, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28888743/htlv-1-infected-thymic-epithelial-cells-convey-the-virus-to-cd4-t-lymphocytes
#11
Luciana Rodrigues Carvalho Barros, Leandra Linhares-Lacerda, Klaysa Moreira-Ramos, Marcelo Ribeiro-Alves, Maria Cristina Machado Motta, Dumith Chequer Bou-Habib, Wilson Savino
The human T-lymphotropic virus type-1 (HTLV-1) is the causative agent of adult T cell leukemia/lymphoma (ATL) and HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). CD4(+)T cells are the main target of HTLV-1, but other cell types are known to be infected, including immature lymphocytes. Developing T cells undergo differentiation in the thymus, through migration and interaction with the thymic microenvironment, in particular with thymic epithelial cells (TEC) the major component of this three dimensional meshwork of non-lymphoid cells...
August 14, 2017: Immunobiology
https://www.readbyqxmd.com/read/28885693/epidemiological-and-molecular-analysis-of-hepatitis-b-virus-infection-in-manicurists-in-central-brazil
#12
Larissa Dos Santos Pereira Cavaretto, Ana Rita Coimbra Motta-Castro, Sheila Araujo Teles, Fernanda Queiroz de Souza, Wesley Marcio Cardoso, Grazielli Rocha de Rezende, Tayana Serpa Ortiz Tanaka, Larissa Melo Bandeira, Gabriela Alves Cesar, Marco Antonio Moreira Puga, Bruna Bentos Nepomuceno, Bárbara Vieira do Lago, Sonia Maria Fernandes Fitts
OBJECTIVES: The aim of this study was to investigate the serological and molecular prevalence of hepatitis B virus (HBV) infection in 514 manicurists/pedicurists and identify the risk factors related with this infection. METHODS: Samples were tested for HBV serological markers, hepatitis C virus (HCV) and human immunodeficiency virus (HIV) by ELISA. Anti-HBc-positive samples were tested to investigate occult hepatitis B by PCR. HBsAg-positive samples were genotyped and the viral loads of HBV-DNA positive samples were quantified...
September 8, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28884286/combination-of-irinotecan-oxaliplatin-and-5-fluorouracil-as-a-rechallenge-regimen-for-heavily-pretreated-metastatic-colorectal-cancer-patients
#13
Gustavo Dos Santos Fernandes, Maria Ignez Braghiroli, Michelle Artioli, Ana Carolina Carvalho Rocha Paterlini, Marcela Crosara Teixeira, Brenda Pires Gumz, Daniel da Motta Girardi, Oddone F M Braghiroli, Frederico Perego Costa, Paulo M Hoff
PURPOSE: Our objective was to evaluate the benefit of re-exposing patients with refractory metastatic colorectal cancer (mCRC) to a combination of oxaliplatin, irinotecan and 5-fluorouracil treatment. METHODS: We retrospectively analysed patients with mCRC who received a combination of oxaliplatin, irinotecan and fluorouracil as a rechallenge regimen after progressing on the same drugs. Both FOLFOXIRI and FOLFIRINOX were used. Toxicity was evaluated for each treatment cycle, and survival analysis was performed using the Kaplan-Meier method...
September 8, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28884058/nanostructures-for-sensors-electronics-energy-and-environment-iii
#14
EDITORIAL
Nunzio Motta
No abstract text is available yet for this article.
2017: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/28876483/htlv-1-intrafamilial-transmission-among-japanese-immigrants-in-brazil
#15
Larissa M Bandeira, Silvia N O Uehara, Marco A M Puga, Grazielli R Rezende, Ana C P Vicente, João Américo Domingos, Bárbara Vieira do Lago, Christian Niel, Ana Rita Coimbra Motta-Castro
Human T-lymphotropic virus type 1 (HTLV-1) is the etiological agent of adult T-cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The aim of this study was to investigate the intrafamilial transmission of HTLV-1 among Japanese immigrants and their descendants living in a non-endemic area of central Brazil. Six families were investigated. Thirty-seven relatives of the six index cases were tested by ELISA for the presence of anti-HTLV antibodies, and the positive cases were confirmed by Western blot...
September 6, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28875505/atlantic-bats-a-dataset-of-bat-communities-from-the-atlantic-forests-of-south-america
#16
Renata de Lara Muylaert, Richard D Stevens, Carlos Eduardo Lustosa Esbérard, Marco Aurelio Ribeiro Mello, Guilherme Siniciato Terra Garbino, Luiz H Varzinczak, Deborah Faria, Marcelo de Moraes Weber, Patricia Kerches Rogeri, André Luis Regolin, Hernani Fernandes Magalhães de Oliveira, Luciana de Moraes Costa, Marília A S Barros, Gilberto Sabino-Santos, Mara Ariane Crepaldi de Morais, Vinicius Silva Kavagutti, Fernando C Passos, Emma-Liina Marjakangas, Felipe Gonçalves Motta Maia, Milton Cezar Ribeiro, Mauro Galetti
Bats are the second most diverse mammal order and they provide vital ecosystem functions (e.g., pollination, seed dispersal, and nutrient flux in caves) and services (e.g., crop pest suppression). Bats are also important vectors of infectious diseases, harboring more than 100 different virus types. In the present study, we compiled information on bat communities from the Atlantic Forests of South America, a species-rich biome that are highly threatened by habitat loss and fragmentation. ATLANTIC BATS dataset comprises 135 quantitative studies carried out in 205 sites, which cover most vegetation types of the tropical and subtropical Atlantic Forest: dense ombrophilous forest, mixed ombrophilous forest, semideciduous forest, deciduous forest, savanna, steppe, and open ombrophilous forest...
September 6, 2017: Ecology
https://www.readbyqxmd.com/read/28860675/changes-of-forest-cover-and-disturbance-regimes-in-the-mountain-forests-of-the-alps
#17
P Bebi, R Seidl, R Motta, M Fuhr, D Firm, F Krumm, M Conedera, C Ginzler, T Wohlgemuth, D Kulakowski
Natural disturbances, such as avalanches, snow breakage, insect outbreaks, windthrow or fires shape mountain forests globally. However, in many regions over the past centuries human activities have strongly influenced forest dynamics, especially following natural disturbances, thus limiting our understanding of natural ecological processes, particularly in densely-settled regions. In this contribution we briefly review the current understanding of changes in forest cover, forest structure, and disturbance regimes in the mountain forests across the European Alps over the past millennia...
March 15, 2017: Forest Ecology and Management
https://www.readbyqxmd.com/read/28855892/albuminuria-reduction-after-high-dose-of-vitamin-d-in-patients-with-type-1-diabetes-mellitus-a-pilot-study
#18
João Soares Felício, Alana Ferreira de Oliveira, Amanda Soares Peixoto, Ana Carolina Contente Braga de Souza, João Felício Abrahão Neto, Franciane Trindade Cunha de Melo, Carolina Tavares Carvalho, Manuela Nascimento de Lemos, Sávio Diego Nascimento Cavalcante, Fabricio de Souza Resende, Márcia Costa Dos Santos, Ana Regina Motta, Luísa Corrêa Janaú, Elizabeth Sumi Yamada, Karem Miléo Felício
BACKGROUND: Some studies suggest an association between diabetic kidney disease (DKD) and vitamin D (VD), but there is no data about the effect of high dose of VD on DKD in type 1 diabetes mellitus (T1DM). Our pilot study aims to evaluate albuminuria reduction in patients with T1DM supplemented with high dose of VD. METHODS: 22 patients received doses of 4,000 and 10,000 IU/day of cholecalciferol for 12 weeks according to patient's previous VD levels. They were submitted to continuous glucose monitoring system, 24 hours ambulatory blood pressure monitoring and urine albumin-to-creatinine ratio before and after VD supplementation...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28846741/decoding-social-intentions-in-human-prehensile-actions-insights-from-a-combined-kinematics-fmri-study
#19
Maria Grazia Di Bono, Chiara Begliomini, Sanja Budisavljevic, Luisa Sartori, Diego Miotto, Raffaella Motta, Umberto Castiello
Consistent evidence suggests that the way we reach and grasp an object is modulated not only by object properties (e.g., size, shape, texture, fragility and weight), but also by the types of intention driving the action, among which the intention to interact with another agent (i.e., social intention). Action observation studies ascribe the neural substrate of this 'intentional' component to the putative mirror neuron (pMNS) and the mentalizing (MS) systems. How social intentions are translated into executed actions, however, has yet to be addressed...
2017: PloS One
https://www.readbyqxmd.com/read/28842450/neuroinflammation-drives-anxiety-and-depression-in-relapsing-remitting-multiple-sclerosis
#20
Silvia Rossi, Valeria Studer, Caterina Motta, Serena Polidoro, Jacopo Perugini, Giulia Macchiarulo, Ambra Mara Giovannetti, Lorena Pareja-Gutierrez, Andrea Calò, Isabella Colonna, Roberto Furlan, Gianvito Martino, Diego Centonze
OBJECTIVE: To explore the inflammatory processes in the pathogenesis of psychiatric symptoms and the prognostic value of psychiatric comorbidities in multiple sclerosis (MS). METHODS: Four hundred five patients with relapsing-remitting (RR) MS underwent psychiatric evaluation by means of Beck Depression Inventory II (BDI-II) and State/Trait Anxiety Inventory (STAI-Y). The inflammatory activity level was assessed by MRI. In a subset of 111 treatment-naive patients, CSF levels of proinflammatory cytokines were determined...
August 25, 2017: Neurology
keyword
keyword
47345
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"