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https://www.readbyqxmd.com/read/29244711/flavonoids-and-ellagitannins-characterization-antioxidant-and-cytotoxic-activities-of-phyllanthus-acuminatus-vahl
#1
Mirtha Navarro, Ileana Moreira, Elizabeth Arnaez, Silvia Quesada, Gabriela Azofeifa, Felipe Vargas, Diego Alvarado, Pei Chen
The phenolic composition of leaves from Phyllanthus acuminatus L., a plant commonly used in Costa Rica as traditional medicine, was studied using UPLC-ESI-MS on an enriched phenolic extract. A total of 20 phenolic compounds were identified, comprising eight flavonoids (two flavanones-pinocembrin isomers and six derivatives from apigenin, chrysin, quercetin, and kaempferol); seven ellagitannins, two flavan-3-ols (prodelphinidin B dimer and (epi)gallocatechin); and three phenolic acids (ellagic acid, trimethylellagic acid, and ferulic acid)...
December 15, 2017: Plants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29243674/turmeric-a-condiment-cosmetic-and-cure
#2
REVIEW
Hima Gopinath, Kaliaperumal Karthikeyan
Turmeric (Curcuma longa L.) is an integral part of Asian culture and cuisine. It has been used in traditional medicine since centuries. A myriad of health benefits have been attributed to it. Curcumin, the most biologically active curcuminoid in turmeric, is being investigated in pre-clinical and clinical trials for its role in disease prevention and cure. It has antioxidant, anti-inflammatory, antineoplastic, anti-proliferative and antimicrobial effects. We review the chemistry of this plant, its cultural relevance in Indian skin care, and its uses in dermatology...
December 14, 2017: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/29243580/coumarins-as-promising-scaffold-for-the-treatment-of-age-related-diseases-an-overview-of-the-last-five-years
#3
Giovanna Lucia Delogu, Maria Joao Matos
Degenerative diseases are becoming increasingly prevalent with the aging of the human population. The twentieth century witnessed a significant demographic change in the industrialized world that is currently followed by a similar shift of life expectancy to upper age ranges in Asia, Africa, and Middle and South America. A rising tide of chronic age-dependent diseases will soon present serious challenges for these countries. Age-related diseases are commonly seen in older patients. More than 40% of adults 60 and older have a combination of risk factors known as metabolic syndrome, which increases the risk for developing degenerative disorders, and certain cancers...
December 14, 2017: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/29243333/psoralea-corylifolia-l-ethnobotanical-biological-and-chemical-aspects-a-review
#4
REVIEW
Fiaz Alam, Gul Nawaz Khan, Muhammad Hassham Hassan Bin Asad
Psoralea corylifolia L. (Leguminosae) is a well-known traditional medicinal plant used from ancient times for treatment of various ailments. It is widely distributed and an important part of therapeutics in Ayurveda and in Chinese medicines. The aim of this review is to present comprehensive and most up to date report on its ethnobotanical, ethnopharmacological, clinical, phytochemical, and side effects. Studies on the ethnobotanical, ethnopharmacological, clinical, phytochemical, and side effects of P. corylifolia were published until year 2017 and were searched using various scientific databases...
December 15, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29241765/oliveria-decumbens-essential-oil-chemical-compositions-and-antimicrobial-activity-against-the-growth-of-some-clinical-and-standard-strains-causing-infection
#5
Behrooz Alizadeh Behbahani, Farideh Tabatabaei Yazdi, Alireza Vasiee, Seyed Ali Mortazavi
Oliveria decumbens as a valuable medicinal plant is extensively used in traditional medicine. clinical and standard strains causing infection resistance to antimicrobial agents, is one of the important problems in medicine. The aim of this study was to investigate the antibacterial activities and phytochemical analysis of Oliveria decumbens essential oil on the growth of some clinical and standard strains causing infection (Pseudomonas aerogenes, Escherichia coli, Streptococcus pyogenes and Staphylococcus epidermidis)...
December 11, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29241674/ethnomedicinal-plant-diversity-in-thailand
#6
Methee Phumthum, Kamonnate Srithi, Angkhana Inta, Auemporn Junsongduang, Kornkanok Tangjitman, Wittaya Pongamornkul, Chusie Trisonthi, Henrik Balslev
ETHNOPHARMACOLOGICAL RELEVANCE: Plants have provided medicine to humans for thousands of years, and in most parts of the world people still use traditional plant-derived medicine. Knowledge related to traditional use provides an important alternative to unavailable or expensive western medicine in many rural communities. At the same time, ethnomedicinal discoveries are valuable for the development of modern medicine. Unfortunately, globalization and urbanization causes the disappearance of much traditional medicinal plant knowledge...
December 11, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29241315/natural-antioxidant-extracts-as-food-preservatives
#7
Norma F Santos-Sánchez, Raúl Salas-Coronado, Rogelio Valadez-Blanco, Beatriz Hernández-Carlos, Paula C Guadarrama-Mendoza
The food industry is becoming more specialized and processing methods are continuously being developed to meet consumer needs. Consumers demand products that are safe and preferably free of synthetic additives. These additives are associated with health effects, in most cases without reasonable justification. Consequently, consumers are looking for clearly labelled products that guarantee the absence of synthetic additives. This has led to the need to search for natural additives, which the food industry claims arenatural antioxidant preservatives...
October 2017: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/29240701/25th-conference-of-gp2a
#8
Michael D Threadgill, Susan E Matthews, Francesca Giuntini
The 25th Conference of GP2A was held on 31 August and 1 September 2017 in Liverpool, UK, with the aim of exchange of ideas and experience, particularly amongst young medicinal chemists. Topics included bioactive compounds from plants and lichens, and design and development of drugs. Abstracts of invited lectures, proffered oral presentations, flash presentations and posters presented during the meeting are collected in this report.
December 14, 2017: Pharmaceuticals
https://www.readbyqxmd.com/read/29239871/integrative-medicine-as-an-adjunct-to-orthopaedic-surgery
#9
James R Ficke, Nathan M Moroski, Steven D Ross, Ranjan Gupta
Patients often seek nontraditional forms of treatment, including alternative/complementary medical options, such as chiropractic care and acupuncture, to meet their personal needs. In the United States, interest has grown in methods to reduce pain and improve function through Ayurvedic medicine, which uses plant-based supplements, such as turmeric. Traditional allopathic medicine attempts to provide patients with evidence-based therapeutic regimens for their musculoskeletal conditions. Integrative medicine often is used to prevent and manage the sequelae associated with injuries and illnesses; however, competitive athletes and military personnel use complementary medicine for performance enhancement...
December 11, 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29238889/immunomodulatory-effects-of-rhodomyrtus-tomentosa-leaf-extract-and-its-derivative-compound-rhodomyrtone-on-head-kidney-macrophages-of-rainbow-trout-oncorhynchus-mykiss
#10
Pinanong Na-Phatthalung, Mariana Teles, Supayang Piyawan Voravuthikunchai, Lluís Tort, Camino Fierro-Castro
Rhodomyrtus tomentosa is a medicinal plant that shows biological effects including immunomodulatory activity on human and other mammals but not in fish. In this study, we evaluated the in vitro immunomodulatory effects of R. tomentosa leaf extract and its active compound, rhodomyrtone, on the immune responses, using rainbow trout (Oncorhynchus mykiss) head kidney (HK) macrophages as a model. The tested immune functions included the expression of genes involved in innate immune and inflammatory responses and the production of reactive oxygen species (ROS)...
December 13, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/29238474/cytotoxic-and-apoptotic-effects-of-root-extract-and-tanshinones-isolated-from-perovskiaabrotanoides-kar
#11
Arehzoo Zaker, Javad Asili, Parvaneh Abrishamchi, Zahra Tayarani-Najaran, Seyed Hadi Mousavi
Objectives: Perovskiaabrotanoides Kar., from family Lamiaceae, is a little known medicinal plant growing in various regions of Iran. In the present study, cryptotanshinone (CT), tanshinone 2A (Tan2A), and hydroxycryptotanshinone (HCT) were isolated and purified from the roots of P. abrotanoides. In addition, cytotoxic and apoptotic effects of total root extract (TE) and three purified tanshinones were investigated in human cervical carcinoma (HeLa) and human breast cancer (MCF-7) cell lines...
December 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29237703/genome-assembly-and-annotation-of-the-medicinal-plant-calotropis-gigantea-a-producer-of-anti-cancer-and-anti-malarial-cardenolides
#12
Genevieve M Hoopes, John P Hamilton, Jeongwoon Kim, Dongyan Zhao, Krystle Wiegert-Rininger, Emily Crisovan, C Robin Buell
Calotropis gigantea produces specialized secondary metabolites known as cardenolides which have anti-cancer and anti-malarial properties. Although transcriptomic studies have been conducted in other cardenolide-producing species, no nuclear genome assembly for an Asterid cardenolide-producing species has been reported to date. A high quality de novo assembly was generated for C. gigantea, representing 157,284,427 bp with an N50 scaffold size of 805,959 bp, for which quality assessments indicated a near complete representation of the genic space...
December 12, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29237384/ros-scavenging-and-anti-tyrosinase-properties-of-crocetin-on-b16f10-murine-melanoma-cells
#13
Seyed Hamed Hashemi-Shahri, Alireza Golshan, Seyed Ahmad Mohajeri, Javad Baharara, Elaheh Amini, Farzaneh Salek, Amirhossein Sahebkar, Zahra Tayarani-Najaran
BACKGROUND: Crocus sativus (Iridaceae) has been traditionally used in the Iranian folk medicine and as a culinary additive. Major components of the plant that are responsible for biological properties are saffranal, crocin, picrocrocin and crocetin. Although the level of crocetin is not high, some of the important activities of saffron such as antioxidant activity have been attributed to crocetin. OBJECTIVE: In the present study, we investigated the effects of crocetin on melanogenesis in B16 melanoma cells...
December 13, 2017: Anti-cancer Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/29237294/mutagenicity-evaluation-of-anastatica-hierochuntica-l-aqueous-extract-in-vitro-and-in-vivo
#14
Siti Rosmani Md Zin, Zahurin Mohamed, Mohammed A Alshawsh, Won F Wong, Normadiah M Kassim
Anastatica hierochuntica L. ( A. hierochuntica), a folk medicinal plant, was evaluated for mutagenic potential via in vitro and in vivo assays. The in vitro assay was conducted according to modified Ames test, while the in vivo study was performed according to Organisation for Economic Co-operation and Development guideline for mammalian erythrocyte micronucleus assay. Four groups ( n= 5 males and 5 females per group) Sprague Dawley rats were randomly chosen as the negative control, positive control (received a single intramuscular injection of cyclophosphamide 50 mg/kg), 1000 and, 2000 mg/kg A...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29236852/antifungal-activities-of-the-essential-oil-and-its-fractions-rich-in-sesquiterpenes-from-leaves-of-casearia-sylvestris-sw
#15
Flaviane G Pereira, Ronaldo Marquete, Levy T Domingos, Marco E N Rocha, Antonio Ferreira-Pereira, Elisabeth Mansur, Davyson L Moreira
Casearia genus (Salicaceae) is found in sub-tropical and tropical regions of the world and comprises about 160-200 species. It is a medicinal plant used in South America, also known as "guaçatonga", "erva-de-tiú", "cafezinho-do-mato". In Brazil, there are about 48 species and 12 are registered in the State of Rio de Janeiro, including Casearia sylvestris Sw. There are many studies related to the chemical profile and cytotoxic activities of extracts from these plants, although few studies about the antifungal potential of the essential oil have been reported...
December 11, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29236070/lc-ms-ms-tandem-mass-spectrometry-for-analysis-of-phenolic-compounds-and-pentacyclic-triterpenes-in-antifungal-extracts-of-terminalia-brownii-fresen
#16
Enass Y A Salih, Pia Fyhrquist, Ashraf M A Abdalla, Abdelazim Y Abdelgadir, Markku Kanninen, Marketta Sipi, Olavi Luukkanen, Mustafa K M Fahmi, Mai H Elamin, Hiba A Ali
Decoctions and macerations of the stem bark and wood of Terminalia brownii Fresen. are used in traditional medicine for fungal infections and as fungicides on field crops and in traditional granaries in Sudan. In addition, T. brownii water extracts are commonly used as sprays for protecting wooden houses and furniture. Therefore, using agar disc diffusion and macrodilution methods, eight extracts of various polarities from the stem wood and bark were screened for their growth-inhibitory effects against filamentous fungi commonly causing fruit, vegetable, grain and wood decay, as well as infections in the immunocompromised host...
December 13, 2017: Antibiotics
https://www.readbyqxmd.com/read/29235286/-growth-rings-in-roots-of-seven-sect-paeonia-species-and-its-application-on-identification-of-paeoniae-radix-rubra
#17
Shan-Shan Chu, Liang-Ping Zha, Hai-Yan Duan, Tao Xu, Hua-Sheng Peng
The growth years of medicinal materials are closely related to their quality, and "Herb-chronology" has been used to determine the growth years of perennial dicotyledonous plants in recent years. On the basis of conventional paraffin section and freehand section, the anatomical study on roots of seven Sect. Paeonia species and main roots of cultivated Paeonia lactiflora was conducted in this paper. The results showed that, there existed some differences in microstructure of the seven species such as P. lactiflora, P...
October 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29235279/-advance-of-a-representative-traditional-tibetan-medicine-meconopsis-horridula-on-its-phytochemical-and-pharmacological-aspects
#18
REVIEW
Feng Zhao, He-Xin-Ge Zhang, Rui-Feng Bai, Bing-Zhao Tu, Xiao-Li Gao, Peng-Fei Tu, Xing-Yun Chai
Meconopsis horridula is one of alpine plants belonging to family Papaveraceae, mainly distributed in Himalaya Range area. M. horridula is a rare alpine flower, and is a kind of traditional Tibetan medicine, which has been included in more than 40 compound formulae, having efficacies of clearing away heat and alleviating pain, activating blood circulation to remove stasis, traditionally used for the treatment of fractures, injuries, and chest and back pains. Modern research shows that the whole plant of M. horridula contains alkaloids, flavonoids, and terpenes, and its pharmacological activities including antitumor, antivirus and myocardial protection etc...
October 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29234988/identification-characterization-and-expression-analysis-of-genes-involved-in-steroidal-saponin-biosynthesis-in-dracaena-cambodiana
#19
Jia-Hong Zhu, Hui-Liang Li, Dong Guo, Ying Wang, Hao-Fu Dai, Wen-Li Mei, Shi-Qing Peng
Dracaena cambodiana is a traditional medicinal plant used for producing dragon's blood. The plants and dragon's blood of D. cambodiana contain a rich variety of steroidal saponins. However, little is known about steroidal saponin biosynthesis and its regulation in D. cambodiana. Here, 122 genes encoding enzymes involved in steroidal saponin biosynthesis were identified based on transcriptome data, with 29 of them containing complete open reading frames (ORF). Transcript expression analysis revealed that several genes related to steroidal saponin biosynthesis showed distinct tissue-specific expression patterns; the expression levels of genes encoding the key enzymes involved in the biosynthesis and early modification of steroidal saponins were significantly down-regulated in the stems in response to the inducer of dragon's blood, exhibiting positive correlations with the content of steroidal saponins...
December 12, 2017: Journal of Plant Research
https://www.readbyqxmd.com/read/29234446/medicinal-plants-from-north-and-central-america-and-the-caribbean-considered-toxic-for-humans-the-other-side-of-the-coin
#20
REVIEW
Angel Josabad Alonso-Castro, Fabiola Domínguez, Alan Joel Ruiz-Padilla, Nimsi Campos-Xolalpa, Juan Ramón Zapata-Morales, Candy Carranza-Alvarez, Juan Jose Maldonado-Miranda
The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out using published scientific material on native plants from Mexico, Central America, and the Caribbean, which describe the ethnobotanical and toxicological information of medicinal plants empirically considered to be toxic...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
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