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https://www.readbyqxmd.com/read/28749412/multi-targeting-andrographolide-a-novel-nf-%C3%AE%C2%BAb-inhibitor-as-a-potential-therapeutic-agent-for-stroke
#1
REVIEW
Chih-Hao Yang, Ting-Lin Yen, Chia-Yuan Hsu, Philip-Aloysius Thomas, Joen-Rong Sheu, Thanasekaran Jayakumar
A key focus in the field of drug discovery has been motivated by the neuroprotection of natural compounds. Cerebral ischemia is a multifaceted pathological process with a series of mechanisms, and a perspective for the development of neuroprotectants from traditional herbal medicine or natural products is a promising treatment for this disease. Natural compounds with the effects of anti-oxidation, anti-inflammation, anti-apoptosis, and neurofunctional regulation exhibit therapeutic effects on experimental ischemic brain injury...
July 27, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28749102/an-exploration-of-phytochemicals-from-simaroubaceae
#2
Biba Vikas, B S Akhil, P S R Suja, K Sujathan
Natural products such as plants, animals and minerals have been the basis of treatment of human diseases. Herbal remedies have been used for the treatment of many ailments. Many compounds have been derived from the plant species mentioned in the ancient texts of Indian system of medicine for the treatment of a number of ailments. The R and D thrust in the pharmaceutical sector is focused on development of new drugs, innovative/indigenous processes for known drugs and development of plant based drugs through investigation of leads from the traditional systems of medicine...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28749045/factors-related-to-recurrence-of-idiopathic-granulomatous-mastitis-what-do-we-learn-from-a-multicentre-study
#3
Erdal Uysal, Atilla Soran, Efe Sezgin
BACKGROUND: Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory disease of the breast with unknown aetiology. Its treatment is controversial and the recurrence rate is high. The objectives of this study were to examine the demographic, sociocultural and clinical characteristics observed among a large cohort of IGM patients from Turkey and to identify factors related to the recurrence of IGM. METHODS: The study was designed as a multicentre retrospective study including 22 breast centres in Turkey...
July 27, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28748852/pretreated-glehnia-littoralis-extract-prevents-neuronal-death-following-transient-global-cerebral-ischemia-through-increases-of-superoxide-dismutase-1-and-brain-derived-neurotrophic-factor-expressions-in-the-gerbil-hippocampal-cornu-ammonis-1-area
#4
Joon Ha Park, Tae-Kyeong Lee, Bing-Chun Yan, Bich-Na Shin, Ji Hyeon Ahn, In Hye Kim, Jeong Hwi Cho, Jae-Chul Lee, In Koo Hwang, Jong Dai Kim, Seongkweon Hong, Young Joo Lee, Moo-Ho Won, Il Jun Kang
BACKGROUND: Glehnia littoralis, as a traditional herbal medicine to heal various health ailments in East Asia, displays various therapeutic properties including antioxidant effects. However, neuroprotective effects of G. littoralis against cerebral ischemic insults have not yet been addressed. Therefore, in this study, we first examined its neuroprotective effects in the hippocampus using a gerbil model of transient global cerebral ischemia (TGCI). METHODS: Gerbils were subjected to TGCI for 5 min...
August 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28748433/a-supplement-to-prof-shoji-shibata-s-achievements-the-history-of-sh%C3%A5-s%C3%A5-in-medicines-and-the-reason-why-magnolia-obovata-old-name-hoogashiwa-was-not-given-a-chinese-herbal-name-in-japan-s-oldest-anthology-man-y%C3%A5-sh%C3%A5
#5
REVIEW
Takeshi Kinoshita
Prof. Shoji Shibata (1916-2016) left behind remarkable achievements in the field of the history of pharmacy. Among those, the scientific survey on medicines preserved in Shōsō-in, globally known as the World Cultural Heritage, is of particular interest, drawing wide attention from scholars to the general public. Its most spectacular and also shocking study in the field of pharmacognosy will be the one on the true origin of Kōboku (Houpu) that seems quite ordinary from its name. Prof. Shibata revealed that it is of juglandaceous origin that is completely different from what is known today under the same name...
July 26, 2017: Journal of Natural Medicines
https://www.readbyqxmd.com/read/28748170/the-effects-of-setarud-on-the-immunological-status-of-hiv-positive-patients-efficacy-of-a-novel-multi-herbal-drug
#6
Mehdi Gholamzadeh Baeis, Ghasem Amiri, Mojtaba Miladinia
OBJECTIVE: This study examines the effect of the addition of IMOD, a novel multi-herbal drug to the highly active anti-retroviral therapy (HAART) regimen, on the immunological status of HIV-positive patients. MATERIALS AND METHODS: A randomized two-parallel-group (HAART group versus HAART+IMOD group), pretest-posttest design was used.Sixty patients with indications for treatment with the HAART regimen participated. One week before and 2 days after the treatments, immunological parameters including total lymphocyte count (TLC) and CD4 cell count were assessed...
May 2017: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28747209/hypoglycemic-effects-of-acacia-nilotica-in-type-ii-diabetes-a-research-proposal
#7
Nasibeh Roozbeh, Leili Darvish, Fatemeh Abdi
OBJECTIVE: Diabetes mellitus is a common metabolic disorder throughout the world which can negatively affect the function of various body organs. Due to their availability and few side effects, herbal medicines have been proposed as suitable alternatives in the management of diabetes. Previous studies have confirmed the anti diabetic properties of Acacia nilotica. The hypoglycemic effects of this plant have been attributed to its role in stimulating the islets of Langerhans to produce more insulin...
July 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28745082/chinese-herbal-medicine-jian-pi-li-gan-decoction-improved-survival-of-nonresectable-hepatocellular-cancer-after-radiofrequency-ablation-a-retrospective-study
#8
Chengwu Tang, Wenming Feng, Lianjin Qin, Ying Bao
OBJECTIVE: To observe the effect of Jian Pi Li Gan Decoction (JPLGD) on long-term survival of nonresectable hepatocellular cancer (HCC) after radiofrequency ablation (RFA). METHODS: Between January 2010 and February 2013, 95 patients with nonresectable HCC treated by RFA in our hospital were enrolled, of whom 47 patients received JPLGD accompanying RFA (JPLGD group), and 48 patients received RFA alone (control group). Medical records of these patients were retrospectively analyzed...
July 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28744942/utilization-of-western-medicine-and-traditional-chinese-medicine-among-patients-with-alzheimer-s-disease-in-taiwan-a-nationwide-population-based-study
#9
C-Y Lai, M-Y Wu, J-H Chiang, M-F Sun, Y-H Chen, C-T Chang, J-G Lin, H-R Yen
BACKGROUND AND PURPOSE: Large-scale studies of utilization of medical services among patients with Alzheimer's disease (AD) are lacking. We aimed to investigate the usage of Western medicine and traditional Chinese medicine (TCM) among these patients in Taiwan. METHODS: We analyzed one million samples from the National Health Insurance Research Database in Taiwan. Patients (n = 1814) newly diagnosed with AD in 2001-2010 were divided into TCM users (n = 528) and non-TCM users (n = 1286)...
July 26, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28743274/risk-factors-and-a-prediction-model-for-lower-limb-lymphedema-following-lymphadenectomy-in-gynecologic-cancer-a-hospital-based-retrospective-cohort-study
#10
Kenji Kuroda, Yasuhiro Yamamoto, Manami Yanagisawa, Akira Kawata, Naoya Akiba, Kensuke Suzuki, Kazutoshi Naritaka
BACKGROUND: Lower limb lymphedema (LLL) is a chronic and incapacitating condition afflicting patients who undergo lymphadenectomy for gynecologic cancer. This study aimed to identify risk factors for LLL and to develop a prediction model for its occurrence. METHODS: Pelvic lymphadenectomy (PLA) with or without para-aortic lymphadenectomy (PALA) was performed on 366 patients with gynecologic malignancies at Yaizu City Hospital between April 2002 and July 2014; we retrospectively analyzed 264 eligible patients...
July 25, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28743091/performance-comparison-of-two-herbal-and-industrial-medicines-using-nanoparticles-with-a-starch-cellulose-shell-and-alginate-core-for-drug-delivery-in-vitro-studies
#11
Akbar Esmaeili, Sahar Behzadi
In this study, the performance of two kinds of industrial and herbal drugs encapsulated in nanoparticles with a shell of starch and cellulose and an alginate core were examined as a new technique for nanoparticle drug delivery. The test method involved creating a suspension of starch and alginate, which was then dried, mixed with cellulose, and heated to form core-shell nanoparticles. The industrial drug calcitonin and an extract of the herb Amaranthus retroflexcus L. were added separately and in combination to the nanoparticles, and the performance of each configuration was evaluated...
July 18, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28742505/effects-of-a-hops-humulus-lupulus-l-dry-extract-supplement-on-self-reported-depression-anxiety-and-stress-levels-in-apparently-healthy-young-adults-a-randomized-placebo-controlled-double-blind-crossover-pilot-study
#12
Ioannis Kyrou, Aimilia Christou, Demosthenes Panagiotakos, Charikleia Stefanaki, Katerina Skenderi, Konstantina Katsana, Constantine Tsigos
OBJECTIVE: The Humulus lupulus L. plant (hops) is used as a herbal medicinal product for anxiety/mood disorders. Our aim was to study the effects of a hops dry extract on self-reported depression, anxiety and stress levels in young adults. DESIGN: Apparently healthy young adults from our university completed the Depression Anxiety Stress Scale-21 (DASS-21) and those reporting at least mild depression, anxiety and stress were invited to complete the study intervention...
April 2017: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28742368/borapetoside-e-a-clerodane-diterpenoid-extracted-from-tinospora-crispa-improves-hyperglycemia-and-hyperlipidemia-in-high-fat-diet-induced-type-2-diabetes-mice
#13
Yuhui Xu, Yanfen Niu, Yuan Gao, Fang Wang, Wanying Qin, Yanting Lu, Jing Hu, Li Peng, Jikai Liu, Wenyong Xiong
An insidious increase in the incidence of obesity, insulin resistance, and hyperlipidemia has led to an epidemic of type 2 diabetes worldwide. Tinospora crispa (T. crispa) is a familiar plant traditionally used in herbal medicine for diabetes; however, the major active ingredients of this plant are still unclear. In this study, we identified the therapeutic effects of borapetoside E, a small molecule extracted from T. crispa, in high-fat-diet (HFD)-induced obesity in mice. The therapeutic effects of borapetoside E in HFD-induced obese mice were assessed physiologically, histologically, and biochemically following intraperitoneal injection...
July 25, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28742215/complementary-and-alternative-medicine-use-among-us-adults-with-headache-or-migraine-results-from-the-2012-national-health-interview-survey
#14
Yan Zhang, Jeff A Dennis, Matthew J Leach, Felicity L Bishop, Holger Cramer, Vincent C H Chung, Craig Moore, Romy Lauche, Ron Cook, David Sibbritt, Jon Adams
BACKGROUND: Given the safety concerns regarding pharmacological agents, and the considerable impact of headache and migraine on the sufferer's quality of life, many people seek other treatment options beyond conventional medication and care to address their symptoms; this includes complementary and alternative medicine (CAM). Some CAM interventions have shown promising results in clinical trials of headache and migraine management. Nonetheless, there has been little research exploring the reasons for using CAM, and the types of CAM used, among this population...
July 25, 2017: Headache
https://www.readbyqxmd.com/read/28741457/anthocyanins-possible-role-as-multitarget-therapeutic-agents-for-prevention-and-therapy-of-chronic-diseases
#15
Swathi Putta, Nagendra Sastry Yarla, Ilaria Peluso, Dinesh Kumar Tiwari, Gorla V Reddy, Priyanka Voori Giri, Naresh Kumar, Ramarao Malla, Veera Brahma Chari, Rama Sekhara Reddy D, Ramesh Bade, Mastan Mannarapu, George Barretto, Da-Yong Lu, Vadim V Tarasov, Vladimir N Chubarev, Frederico Fávaro Ribeiro, Luciana Scotti, Marcus T Scotti, M A Kamal, Gjumrakch Aliev, Chinthalapally V Rao, George Perry, Anupam Bishayee
Anthocyanins belong to the flavonoids class of polyphenols and they are water soluble dark colored natural pigments from fruits and vegetables. Dietary consumption of anthocyanins is high compared to other flavonoids, owing to their wide distribution in plant materials. Anthocyanins are the active component in several herbal folk medicines due to its multifaceted medicinal properties. METHOD: This review discusses the anthocyanins as multitarget drugs, which posses antioxidant, antidiabetic, antihyperlipidemic, anti inflammatory, anticarcinogenic, antiulcer, cardioprotective, hepatoprotective, neuroprotective role...
May 19, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28740539/identifying-chinese-herbal-medicine-network-for-endometriosis-implications-from-a-population-based-database-in-taiwan
#16
Pei-Ju Tsai, Yi-Hsuan Lin, Jiun-Liang Chen, Sien-Hung Yang, Yu-Chun Chen, Hsing-Yu Chen
BACKGROUND: Endometriosis is a common but bothersome gynecological disease, and Chinese herbal medicine (CHM) is used for treating endometriosis. The aim of this study is to explore CHM network and core treatments for endometriosis by analyzing nationwide CHM prescription database. METHODS: From 1998 to 2013, the CHM prescriptions made primarily for endometriosis among women diagnosed with endometriosis (ICD-9-CM code: 671) by gynecologists during their reproductive age were collected...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28740537/the-anti-inflammatory-effects-of-invigorating-kidney-and-supplementing-qi-chinese-herbal-formulae-in-asthma-patients
#17
Lingwen Kong, Hongying Zhang, Yuxue Cao, Jingjing Le, Jinfeng Wu, Baojun Liu, Meixia Chen, Yijie Du, Jia Wang, Genfa Wang, Tao Yi, Xianmei Zhou, Gang Wang, Qing Miao, Suyun Li, Naiqing Zhao, Jingcheng Dong
BACKGROUND: The theories of Shen-reinforcement and Qi-supplementation are important in asthma treatment based on traditional Chinese medicine theories. Early studies suggested that Invigorating Kidney and Supplementing Qi herbal formulae, Bu Shen Fang Chuan (BSFC) and Bu Shen Yi Qi (BSYQ), conveyed promising results in asthma treatment. However, the efficacy and safety of the formulae need to be further investigated by a randomized double-blind clinical trial. METHODS: 328 eligible patients were randomly sent to BSFC, BSYQ, and placebo group...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28740171/a-modified-formulation-of-huanglian-jie-du-tang-reduces-memory-impairments-and-%C3%AE-amyloid-plaques-in-a-triple-transgenic-mouse-model-of-alzheimer-s-disease
#18
Siva Sundara Kumar Durairajan, Ashok Iyaswamy, Sravan Gopalakrishna Shetty, Ananth Kumar Kammella, Sandeep Malampati, Wenbin Shang, Chuanbin Yang, Juxian Song, Sookja Chung, Jiandong Huang, Kaliappan Ilango, Quan-Bin Han, Min Li
Alzheimer's disease (AD) is a degenerative disorder typified by progressive deterioration of memory and the appearance of β-amyloid peptide (Aβ)-rich senile plaques. Recently we have identified a novel function of a patented formulation of modified Huanglian-Jie-Tu-Tang (HLJDT-M), a Chinese herbal medicine, in treating AD in in vitro studies (US patent No. 9,375,457). HLJDT-M is a formulation composed of Rhizoma Coptitis, Cortex Phellodendri and Fructus Gardeniae without Radix Scutellariae. Here, we assessed the efficacy of HLJDT-M on a triple transgenic mouse model of AD (3XTg-AD)...
July 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28738710/use-of-traditional-herbal-medicine-as-an-alternative-in-dental-treatment-in-mexican-dentistry-a-review
#19
Cindy Cruz Martínez, Martha Diaz Gómez, Myung Sook Oh
CONTEXT: Herbal therapies are used worldwide to treat health conditions. In Mexico, generations have used them to treat gingivitis, periodontitis, mouth infections, and discoloured teeth. However, few studies have collected scientific evidence on their effects. OBJECTIVE: This study aimed at searching and compiling scientific evidence of alternative oral and dental treatments using medicinal herbs from Mexico. METHODS: We collected various Mexican medicinal plants used in the dental treatment from the database of the Institute of Biology at the National Autonomous University of Mexico...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28738653/development-of-an-efficient-method-for-multi-residue-analysis-of-160-pesticides-in-herbal-plant-by-ethyl-acetate-hexane-mixture-with-direct-injection-to-gc-ms-ms
#20
Sherif M Taha, Sohair A Gadalla
A simple and efficient multi residue method was developed, for the analysis of 160 pesticides by GC-MS/MS in herbal plants. The developed method employs pesticide residue extraction by EtAC/ n. hexane (6:4) with a cleanup step using florisil/ PSA mixture. The optimized conditions have resulted in lower co-extracted matrix components than those extracted using EtAC or MeCN (QuEChERS method), according to FTIR and full scan GC/MS analyses. In addition, the developed method (EtAC/ Hexane) eliminates the evaporation step that is usually performed when using MeCN as an extraction solvent prior to the GC-MS/MS injection...
November 1, 2017: Talanta
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