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Vertebral osteomyelitis

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https://www.readbyqxmd.com/read/29905925/ceftazidime-avibactam-for-refractory-bacteremia-vertebral-diskitis-osteomyelitis-with-pre-vertebral-abscess-and-bilateral-psoas-pyomyositis-secondary-to-klebsiella-pneumoniae-carbapenemase-producing-bacteria-kpc
#1
Rafael De León-Borrás, Julio Álvarez-Cardona, Jorge A Vidal, Humberto M Guiot
A 36-year-old man was admitted to the intensive care unit due to diabetic ketoacidosis and pneumonia requiring mechanical ventilation. Three weeks after admission, he developed a refractory bacteremia with Klebsiella pneumoniae carbapenemase-producing bacteria (KPC). He remained febrile and with bacteremia for six weeks despite therapy with polymyxin B, carbapenems, and amikacin. Imaging studies looking for deep-seated infection revealed vertebral L1-L2 diskitis and osteomyelitis with pre-vertebral abscess and bilateral psoas pyomyositis that were not amenable for drainage...
June 2018: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/29875345/spondylodiscitis-in-paediatric-patients-the-importance-of-early-diagnosis-and-prolonged-therapy
#2
Sonia Bianchini, Andrea Esposito, Nicola Principi, Susanna Esposito
Background: Spondylodiscitis (SD), the concurrent infection of a vertebral disc and the adjacent vertebral bodies, is a very severe disease that can lead to death or cause spinal deformities, segmental instabilities, and chronic pain, which significantly reduces the quality of life for affected patients. Early diagnosis and treatment are essential in order to reduce the risk of negative outcomes. The two cases of SD that are described in this paper might be useful for informing paediatric approaches to children with SD...
June 7, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29808150/osteomyelitis-in-cat-scratch-disease-a-never-ending-dilemma-a-case-report-and-literature-review
#3
D Donà, L Nai Fovino, E Mozzo, G Cabrelle, G Bordin, R Lundin, C Giaquinto, T Zangardi, O Rampon
Background: We performed a review of published case studies of osteomyelitis associated with cat-scratch disease to consolidate existing information on clinical presentation, diagnostic tools, therapy, and outcome, as well as presenting a case of disseminated cat-scratch disease in a 12-year-old female with skull osteomyelitis and spleen involvement. Methods: A search for articles indexed in PubMed, Embase, and Google Scholar was performed with the search terms " Bartonella ," "bone," "osteomyelitis," "osteolytic," and "cat-scratch disease" limited to the immunocompetent pediatric population and articles in English...
2018: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29788907/mycobacterium-avium-complex-vertebral-osteomyelitis-in-the-absence-of-hiv-infection-a-case-report-and-review
#4
Megan E Gray, Peter W Liu, Brian Wispelwey
BACKGROUND: Mycobacterium Avium Complex (MAC) is an established microbiologic cause of pulmonary disease, lymphadenitis, and disseminated disease in cases of advanced immune suppression. However, MAC manifesting as vertebral osteomyelitis is less common, and is particularly rare in the absence of Acquired Immunodeficiency Syndrome (AIDS). Prompt diagnosis of MAC vertebral osteomyelitis is challenging, but necessary to prevent serious morbidity or mortality. CASE PRESENTATION: We report a case of MAC osteomyelitis of the lumbar spine in a 70-year-old woman on extended duration corticosteroid therapy for systemic lupus erythematosus who presented with progressive back pain...
May 22, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29745282/increased-mortality-in-patients-aged-75-years-or-over-with-pyogenic-vertebral-osteomyelitis
#5
Virginie Zarrouk, Julien Gras, Vincent Dubée, Victoire de Lastours, Amanda Lopes, Véronique Leflon, Wassim Allaham, Pierre Guigui, Bruno Fantin
No abstract text is available yet for this article.
May 10, 2018: Infectious Diseases
https://www.readbyqxmd.com/read/29744453/studies-on-the-cytocompatibility-mechanical-and-antimicrobial-properties-of-3d-printed-poly-methyl-methacrylate-beads
#6
David K Mills, Uday Jammalamadaka, Karthik Tappa, Jeffery Weisman
Osteomyelitis is typically a bacterial infection (usually from Staphylococcus) or, more rarely, a fungal infection of the bone. It can occur in any bone in the body, but it most often affects the long bones (leg and arm), vertebral (spine), and bones of the foot. Microbial success in osteomyelitis is due to their ability to form biofilms which inhibit the wound healing process and increases resistance to anti-infective agents. Also, biofilms do not allow easy penetration of antibiotics into their matrix making clinical treatment a challenge...
June 2018: Bioactive Materials
https://www.readbyqxmd.com/read/29718896/salmonella-potsdam-causing-lumbar-vertebral-osteomyelitis-a-case-report
#7
Weike Cheng, Kejian Lian, Deqing Luo, Dasheng Lin, Wanqiang Feng, Hang Xian, Tongtao Li
RATIONALE: Salmonella osteomyelitis is an uncommon complication of salmonella infection, especially the salmonella vertebral osteomyelitis (SVO). PATIENT CONCERNS: We reported a case of a 29-year-old female who presented with serious lower back pain and severe limitation of motion for 50 days with no obvious inducements. She once had a fever up to 39.5°C. Physical examination only revealed limited motion of lower back without neurological complications. The laboratory results revealed no specificity...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29685853/a-successful-antimicrobial-therapeutic-strategy-for-the-discitis-caused-by-aggregatibacter-actinomycetemcomitans-under-unknown-drug-susceptibility-a-case-report
#8
Shunsuke Uno, Yosuke Horiuchi, Takae Uchida, Akiko Yonaha, Takanori Miyata, Eiko Nagano, Takao Kodama, Naoki Hasegawa
Aggregatibacter actinomycetemcomitans is well-known as the pathogen of gingivitis or periodontitis, and discitis or vertebral osteomyelitis cases caused by this organism have rarely been reported. Ampicillin or amoxicillin has been used in the previously reported discitis cases; however, no cases have been reported that is treated with levofloxacin. We report the first published case we chose levofloxacin to treat. We failed to perform the susceptibility testing because of the poor growth and fastidious nature of the organism, and the result of susceptibility of amoxicillin was unclear...
April 20, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29626020/bone-and-joint-infection
#9
Julia Colston, Bridget Atkins
Bone and joint infections include septic arthritis, prosthetic joint infections, osteomyelitis, spinal infections (discitis, vertebral osteomyelitis and epidural abscess) and diabetic foot osteomyelitis. All of these may present through the acute medical take. This article discusses the pathogenesis of infection and highlights the importance of taking a careful history and fully examining the patient. It also emphasises the importance of early surgical intervention in many cases. Consideration of alternative diagnoses, appropriate imaging and high-quality microbiological sampling is important to allow appropriate and targeted antimicrobial therapy...
March 2018: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29619327/-brucella-vertebral-osteomyelitis-misidentified-as-an-ochrobactrum-anthropi-infection
#10
João Trêpa, Patricia Mendes, Raquel Gonçalves, Catarina Chaves, Ana Maria Brás, Andrea Mesa, Isabel Ramos, Rosa Sá, José Gabriel Saraiva da Cunha
Ochrobactrum anthropi is a Gram-negative bacillus widely distributed in nature. It is a low virulence and low pathogenic microorganism and human infection by this agent is considered rare. This microorganism can cause bacteremia and in some cases can lead to osteomyelitis and endocarditis. Included in Brucellaceae family, this bacterium is phenotypically and genetically closely related to the Brucella genus and may be misidentified by rapid identification systems. The authors describe a patient admitted to the Infectious Diseases Department with vertebral osteomyelitis initially identified as Ochrobactrum anthropi ...
2018: IDCases
https://www.readbyqxmd.com/read/29619319/first-reported-case-of-vertebral-osteomyelitis-due-to-erysipelothrix-rhusiopathiae
#11
Matthew L Lorenz, Tara C Bouton, Angela M Caliendo
We describe a case of acute vertebral osteomyelitis with associated prevertebral abscess due to Erysipelothrix rhusiopathiae in an immunocompetent adult with recent known traumatic inoculation from the barb of a fish.
2018: IDCases
https://www.readbyqxmd.com/read/29618171/percutaneous-vertebroplasty-for-osteoporotic-vertebral-compression-fracture
#12
REVIEW
Rachelle Buchbinder, Renea V Johnston, Kobi J Rischin, Joanne Homik, C Allyson Jones, Kamran Golmohammadi, David F Kallmes
BACKGROUND: Percutaneous vertebroplasty remains widely used to treat osteoporotic vertebral fractures although our 2015 Cochrane review did not support its role in routine practice. OBJECTIVES: To update the available evidence of the benefits and harms of vertebroplasty for treatment of osteoporotic vertebral fractures. SEARCH METHODS: We updated the search of CENTRAL, MEDLINE and Embase and trial registries to 15 November 2017. SELECTION CRITERIA: We included randomised and quasi-randomised controlled trials (RCTs) of adults with painful osteoporotic vertebral fractures, comparing vertebroplasty with placebo (sham), usual care, or another intervention...
April 4, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29594240/skull-base-or-cervical-vertebral-osteomyelitis-following-chemoradiotherapy-for-pharyngeal-carcinoma-a-serious-but-treatable-complication
#13
Nafisha Lalani, Shao Hui Huang, Coleman Rotstein, Eugene Yu, Jonathan Irish, Brian O'Sullivan
Osteomyelitis, infection of the bone and marrow, following high dose (chemo-)radiotherapy for head and neck cancer is uncommon and rarely seen in the cervical spine or temporal bone. Due to its proximity to critical structures, osteomyelitis in the latter regions could carry potentially important consequences. Furthermore, involvement near the skull base (e.g. temporal bone and high cervical vertebrae) presents unique challenges in diagnosis (especially in the differentiation from disease recurrence) and treatment, making early detection and timely intervention critical...
January 2018: Clinical and translational radiation oncology
https://www.readbyqxmd.com/read/29573841/lack-of-effect-of-antibiotics-on-biopsy-culture-results-in-vertebral-osteomyelitis
#14
Louis D Saravolatz, Vladimir Labalo, Joel Fishbain, Susan Szpunar, Leonard B Johnson
We report a retrospective study of 173 patients with vertebral osteomyelitis evaluating the effect of antibiotics administered prior to percutaneous and open biopsy cultures. Antibiotics given prior to these biopsies did not have a significant effect on the yield of cultures.
February 26, 2018: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/29569640/comment-on-delayed-intestinal-perforation-and-vertebral-osteomyelitis-after-high-intensity-focused-ultrasound-treatment-for-uterine-leiomyoma
#15
COMMENT
Jennifer K Y Ko, Vincent Y T Cheung
No abstract text is available yet for this article.
March 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29564362/epidemiology-microbiological-diagnosis-and-clinical-outcomes-in-pyogenic-vertebral-osteomyelitis-a-10-year-retrospective-cohort-study
#16
Brian S W Chong, Christopher J Brereton, Alexander Gordon, Joshua S Davis
Background: Pyogenic vertebral osteomyelitis (PVO) is rising in incidence, but optimal methods of investigation and duration of antibiotic therapy remain controversial. Methods: We conducted a single-center retrospective cohort study of PVO at an Australian teaching hospital. We included all adults with a first episode of PVO between 2006 and 2015. PVO was defined based on the presence of prespecified clinical and radiological criteria. The main exposures of interest were investigation strategy and antibiotic treatment...
March 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29561507/an-11-year-old-male-with-vertebral-osteomyelitis-and-a-paraspinal-abscess
#17
Ioannis Kopsidas, Rodanthi Margariti, Maria Gavra, Angeliki Syngelou, Christos Zambakidis, Maria Tsolia, Nikolaos Nikolaidis, Nikos Spyridis
We report the case of an 11 year-old immunocompetent patient presenting with a two-week history of upper back pain, diagnosed with thoracic vertebral osteomyelitis and a paraspinal abscess due to Bartonella henselae. He was treated with gentamicin and doxycycline followed by oral rifampicin and doxycycline with favorable outcome.
March 15, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29454377/chronic-recurrent-multifocal-osteomyelitis-a-case-report
#18
Maria Francesca Gicchino, Mario Diplomatico, Carmela Granato, Daniela Capalbo, Pierluigi Marzuillo, Alma Nunzia Olivieri, Emanuele Miraglia Del Giudice
BACKGROUND: Chronic recurrent multifocal osteomyelitis (CRMO), also known as chronic nonbacterial osteomyelitis, is a rare, noninfectious inflammatory disorder that causes multifocal bone lesions with swelling and pain. Lytic and sclerotic bone lesions could be found on X-ray. Short tau inversion recovery magnetic resonance imaging (STIR MRI) shows bone marrow oedema, bone expansion, lytic areas and periosteal reaction. CRMO is characterized by periodic exacerbations and remissions of unclear/unknown pathogenesis...
February 17, 2018: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29396671/endocarditis-associated-with-vertebral-osteomyelitis-and-septic-arthritis-of-the-axial-skeleton
#19
Oscar Murillo, Imma Grau, Joan Gomez-Junyent, Celina Cabrera, Alba Ribera, Fe Tubau, Carmen Peña, Javier Ariza, Roman Pallares
PURPOSE: The relationship between infective endocarditis (IE) and osteoarticular infections (OAIs) are not well known. We aimed to study the characteristics of patients with IE and OAIs, and the interactions between these two infections. METHODS: An observational study (1993-2014) which includes two cohorts: (1) patients with IE (n = 607) and (2) patients with bacteremic OAIs (n = 458; septic arthritis of peripheral and axial skeleton, and vertebral and peripheral osteomyelitis)...
April 2018: Infection
https://www.readbyqxmd.com/read/29395691/pott-s-disease-in-a-patient-with-subtle-red-flags
#20
Lauren M Cantwell, John C Perkins, David C V Keyes
BACKGROUND: Tuberculosis (TB) is now rare in developed countries; however, it is an important diagnosis for the Emergency Physician to be able to make. Classically thought of as a respiratory disease, TB can present in other ways, making it more challenging to recognize. CASE REPORT: We report the case of a 41-year-old woman who presented to the Emergency Department with a 4-week history of back pain. A diagnosis of T12 osteomyelitis and right psoas muscle abscess was made after magnetic resonance imaging...
March 2018: Journal of Emergency Medicine
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