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https://www.readbyqxmd.com/read/23060587/postoperative-pelvic-hypofractionated-accelerated-radiotherapy-with-cytoprotection-hypoarc-for-high-risk-or-recurrent-prostate-cancer
#1
Michael I Koukourakis, Aikaterini Papadopoulou, Ioannis Abatzoglou, Marianthi Panteliadou, Kyriaki Sismanidou, Stavros Touloupidis
AIM: We evaluated the feasibility and efficacy of postoperative hypofractionated and accelerated radiotherapy supported with amifostine cytoprotection (HypoARC) in patients with high-risk or recurrent prostate cancer. PATIENTS AND METHODS: Fourty-eight patients were recruited (median follow-up=41 months; range=12-84 months). Twenty-one received HypoARC after surgery and 27 at biochemical relapse. Radiotherapy was given with a 3D-conformal technique, delivering 2...
October 2012: Anticancer Research
https://www.readbyqxmd.com/read/22643562/dose-escalation-of-amifostine-for-radioprotection-during-pelvic-accelerated-radiotherapy
#2
MULTICENTER STUDY
Michael I Koukourakis, George Kyrgias, Marianthi Panteliadou, Aikaterini Papadopoulou, Maria Tsiarkatsi, Eli Papachristou, Maria Bebeli
OBJECTIVES: Experimental data suggest a dose-dependent efficacy of amifostine so that the low overall doses used in clinical trials may have masked the full potential of the drug. In this study, we report our experience with the role of escalated doses of amifostine in the protection of pelvic tissues. METHODS: A total of 354 patients with pelvic carcinomas recruited in prospective protocols applying hypofractionated and accelerated radiotherapy (HypoARC) supported with escalated daily doses of amifostine (0, 500, 750, 1000 mg subcutaneously) were analyzed...
August 2013: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/21617234/treatment-of-low-risk-prostate-cancer-with-radical-hypofractionated-accelerated-radiotherapy-with-cytoprotection-hypoarc-an-interim-analysis-of-toxicity-and-efficacy
#3
Michael I Koukourakis, George Kyrgias, Aikaterini Papadopoulou, Marianthi Panteliadou, Alexandra Giatromanolaki, Efthimios Sivridis, Sophia Mavropoulou, Kriton Kalogeris, Pavlos Nassos, Nicolaos Milioudis, Stavros Touloupidis
AIM: Radiobiological analysis of clinical data suggests that prostate cancer has a low α/β ratio, implying that large radiotherapy fractions may better control the disease. Acceleration of radiotherapy may be also of importance in a subset of tumors. In this study we assessed the feasibility and efficacy of a highly accelerated and hypofractionated scheme of radiotherapy (HypoARC), for the treatment of localized low risk prostate cancer. PATIENTS AND METHODS: Fifty-five patients with prostate cancer (T1-2 stage, Gleason score <7 and prostate specific antigen (PSA) <10 ng/ml) were treated with localized conformal 4-field radiotherapy to the prostate and seminal vesicles: 51 Gy were delivered (3...
May 2011: Anticancer Research
https://www.readbyqxmd.com/read/19852064/voiding-dysfunctions-in-children-with-mental-retardation
#4
Pei-Yu Yang, Nai-Hsin Meng, Eric Chieh-lung Chou
AIMS: This study aims to evaluate the voiding disorder and lower urinary tract symptoms in mentally retarded children. METHODS: Fifty-one mentally retarded children (age 7.7 years) was assessed. A volunteer sample comprised of 36 typically developing children (age 6.4 years) served as the comparative group. All participants underwent uroflometric investigation, and residual urine was detected by sonography. Urological history including history of urinary tract infection, incontinence, frequency, and dysurea was collected...
September 2010: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/19556616/prevalence-of-sexually-transmitted-disease-syndromes-in-tribal-population-of-central-india
#5
MULTICENTER STUDY
V G Rao, A Anvikar, D Savargaonkar, J Bhat, R Yadav, B K Tiwary, A Abbad
BACKGROUND: A syndromic approach has been advocated for identification and management of sexually transmitted diseases (STDs) in countries where diagnostic laboratory tests are not consistently available. A community-based cross-sectional study was conducted to discover the prevalence of STD syndromes in tribal population of central India. METHODS: All married men and women in the age group of 15-49 years from selected villages were enumerated by house-to-house visit...
October 2009: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/19281419/long-term-functional-evaluation-of-fecal-continence-after-laparoscopic-assisted-pull-through-for-high-anorectal-malformations
#6
Mohamed S El-Debeiky, Hatem A Safan, Ihab A Shafei, Hesham A Kader, Sameh A Hay
BACKGROUND: The use of laparoscopy while performing an abdominal dissection for the mobilization of rectovesical fistula should have an impact on anorectal function, as compared to the original posterior sagittal anorectoplasty, where muscle complex was not cut and the rectum was pulled in a way similar to the old techniques for the abdominoperineal pull-through. This necessitates a functional reevaluation. MATERIALS AND METHODS: A prospective case study included 15 patients treated with a laparoscopic-assisted pull-through for high anorectal malformation...
April 2009: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/19069492/-transurethral-photoselective-laser-vaporization-in-the-treatment-of-prostatic-adenoma
#7
A A Kamalov, B E Osmolovskiĭ
Progress in laser technologies allowed development of a highly effective method of laser adenomectomy--photoselective vaporization of the prostate (PSVP). The method employs highly potent potassium-titanyl-phosphate (KTP) laser. PSVP with KTP laser (80 W) [GreenLight PV (tm), Laserscope] was made in 40 patients. Duration of surgery averaged 52.4 min, mean time of urethral catheter stay was 14 hours. Complications were insignificant (short-time dysurea--12%, hematurea--8%). Control examination of all the patients 1, 3, 6 and 12 months after PSVP has shown that IPSS diminished by 78% and was 5 points, QoL improved by 50% (2...
September 2008: Urologii︠a︡
https://www.readbyqxmd.com/read/15588678/medicinal-use-of-cochlospermum-tinctorium-in-mali-anti-ulcer-radical-scavenging-and-immunomodulating-activities-of-polymers-in-the-aqueous-extract-of-the-roots
#8
COMPARATIVE STUDY
Cecilie Sogn Nergard, Drissa Diallo, Kari Inngjerdingen, Terje Einar Michaelsen, Tsukasa Matsumoto, Hiroaki Kiyohara, Haruki Yamada, Berit Smestad Paulsen
Cochlospermum tinctorium A. Rich. (Cochlospermaceae) is a widely used medicinal plant in the West African country, Mali. An ethnopharmacological survey was conducted and 106 traditional practitioners interviewed. The roots were the part of the plant reported to be the most frequently used for medicinal purposes. The main indications were to treat jaundice (41), gastro intestinal diseases or ailments (28), malaria (12), schistosomiasis (10) and dysurea (6). A high-molecular weight water extract (25, 50 and 100 mg/kg, body weight) significantly inhibited HCl/ethanol-induced gastric lesions in mice...
January 4, 2005: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/11766005/incidence-of-malignancy-in-microscopic-haematuria-a-study-of-100-cases
#9
A K Bhuiyan, S A Kibria, M A Wahid, S K Roy, A S Jabbar
During June, 1998 to April, 2000, one hundred cases of microscopic haematuria were evaluated. All were symptomatic patient with age ranging from 24-68 years. 70 (70%) cases were male and 30 (30%) cases were female. Commonest presentation was dysurea 70 (70%). Urinary stone disease was the commonest cause found to be present in 25 (25%) cases. Malignant lesion was found in 16 (16%) cases of which bladder tumour was found in 10 (10%) cases.
December 2000: Bangladesh Medical Research Council Bulletin
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