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https://www.readbyqxmd.com/read/28640156/the-impact-of-fiera-a-women-s-personal-care-device-on-genital-engorgement-as-measured-by-thermography-a-proof-of-principle-study
#1
Irwin Goldstein, Sue Goldstein, Leah Millheiser
OBJECTIVE: To determine the degree of vasoengorgement of the external genitalia caused by Fiera, a personal care device developed specifically to increase sexual arousal and interest. Time to onset of self-reported genital sexual arousal and development of responsive sexual desire were also measured. METHODS: This nonblinded, prospective cohort, single-site study was conducted in women without sexual dysfunction between the ages of 18 and 70. Each participant underwent a single-visit procedure that established a baseline temperature of the external genitalia, followed by 15 minutes of Fiera use...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28632182/mint-middleware-for-cooperative-interaction-of-things
#2
Soobin Jeon, Inbum Jung
This paper proposes an Internet of Things (IoT) middleware called Middleware for Cooperative Interaction of Things (MinT). MinT supports a fully distributed IoT environment in which IoT devices directly connect to peripheral devices easily construct a local or global network, and share their data in an energy efficient manner. MinT provides a sensor abstract layer, a system layer and an interaction layer. These enable integrated sensing device operations, efficient resource management, and active interconnection between peripheral IoT devices...
June 20, 2017: Sensors
https://www.readbyqxmd.com/read/28624991/a-new-global-and-comprehensive-model-for-icu-ventilator-performances-evaluation
#3
Nicolas S Marjanovic, Agathe De Simone, Guillaume Jegou, Erwan L'Her
BACKGROUND: This study aimed to provide a new global and comprehensive evaluation of recent ICU ventilators taking into account both technical performances and ergonomics. METHODS: Six recent ICU ventilators were evaluated. Technical performances were assessed under two FIO2 levels (100%, 50%), three respiratory mechanics combinations (Normal: compliance [C] = 70 mL cmH2O(-1)/resistance [R] = 5 cmH2O L(-1) s(-1); Restrictive: C = 30/R = 10; Obstructive: C = 120/R = 20), four exponential levels of leaks (from 0 to 12...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28617909/development-of-a-flow-evolution-network-model-for-the-stress-strain-behavior-of-poly-l-lactide
#4
Maureen L Dreher, Srinidhi Nagaraja, Jorgen Bergstrom, Danika Hayman
Computational modeling is critical to medical device development and has grown in its utility for predicting device performance. Additionally, there is an increasing trend to use absorbable polymers for the manufacturing of medical devices. However, computational modeling of absorbable devices is hampered by a lack of appropriate constitutive models that capture their viscoelasticity and post-yield behavior. The objective of this study was to develop a constitutive model that incorporated viscoplasticity for a common medical absorbable polymer...
June 15, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28612282/probing-of-peripheral-blood-mononuclear-cells-anchoring-on-tnf-alpha-challenged-vascular-endothelia-in-an-in-vitro-model-of-the-retinal-microvascular
#5
Yuan Li, Yao Lu, Qiong Chen, Yuejun Kang, Ling Yu
Retinopathy is a complication of diabetes that affects the eyes; it stems from damage to the microvasculature of the retina and eventually compromises vision. The diagnosis of retinopathy is difficult to make because there are no early symptoms or warning signs. Dysfunction of the retina's microvascular networks is believed to be associated with inflammatory cytokines and tumor necrosis factor alpha (TNF-α). To investigate the effect of these cytokines, such as TNF-α, a polydimethylsiloxane (PDMS)/glass hydride microfluidic device reflecting the physiological structure of the retina's microvasculature was developed...
September 2017: Biomedical Microdevices
https://www.readbyqxmd.com/read/28609818/accessory-devices-frequently-used-for-endoscopic-submucosal-dissection
#6
REVIEW
Hyuk Soon Choi, Hoon Jai Chun
Endoscopic submucosal dissection (ESD) is increasingly being considered an essential component of treatment for early gastrointestinal cancers and subepithelial tumors. The ESD technique owes its popularity to the development of sophisticated instruments used for ESD. With an increase in the number of ESD procedures performed, there is rapid development in the number and types of endoscopic accessory devices used for such procedures. Despite the large numbers of new devices developed and marketed, the use of ESD instruments and accessory devices is largely determined by individual preferences and experiences...
May 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28609454/an-investigation-into-the-effects-of-excipient-particle-size-blending-techniques-and-processing-parameters-on-the-homogeneity-and-content-uniformity-of-a-blend-containing-low-dose-model-drug
#7
Hamad Alyami, Eman Dahmash, James Bowen, Afzal R Mohammed
Powder blend homogeneity is a critical attribute in formulation development of low dose and potent active pharmaceutical ingredients (API) yet a complex process with multiple contributing factors. Excipient characteristics play key role in efficient blending process and final product quality. In this work the effect of excipient type and properties, blending technique and processing time on content uniformity was investigated. Powder characteristics for three commonly used excipients (starch, pregelatinised starch and microcrystalline cellulose) were initially explored using laser diffraction particle size analyser, angle of repose for flowability, followed by thorough evaluations of surface topography employing scanning electron microscopy and interferometry...
2017: PloS One
https://www.readbyqxmd.com/read/28603798/comment-on-robust-scalable-high-throughput-production-of-monodisperse-drops-by-e-amstad-m-chemama-m-eggersdorfer-l-r-arriaga-m-p-brenner-and-d-a-weitz-lab-chip-2016-16-4163
#8
Mitsutoshi Nakajima
This comment on an article that appeared in Lab on a Chip (Amstad et al., Lab Chip, 2016, 16, 4163-4172) provides information on the performance of microchannel (step) emulsification devices developed by the Nakajima Group.
June 12, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28603796/reply-to-the-comment-on-robust-scalable-high-throughput-production-of-monodisperse-drops-by-m-nakajima-lab-chip-2017-17-doi-10-1039-c7lc00181a
#9
E Amstad, D A Weitz
This reply to the comment by Nakajima on our article that appeared in Lab on a Chip (E. Amstad, M. Chemama, M. Eggersdorfer, L. R. Arriaga, M. Brenner and D. A. Weitz, Lab Chip, 2016, 16, 4163-4172) highlights the differences between the microchannel step emulsification devices developed by the Nakajima group and the millipede device reported by us in Lab on a Chip.
June 12, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28602524/monitoring-the-effectiveness-of-the-vacuum-bell-during-pectus-excavatum-treatment-technical-innovation
#10
Sergio B Sesia, David Hradetzky, Frank-Martin Haecker
BACKGROUND: The vacuum bell (VB) is a valid and the only non-invasive treatment for pectus excavatum (PE). To elevate the sternum the patient himself creates a differential negative pressure inside the VB using a hand pump. A distance and differential pressure measuring device (DPMD) enables us for the first time to assess objectively those parameters. METHODS: After approval by the institutional review board, 53 patients recruited from our outpatient clinic were included in this retrospective study and distributed into three groups (group 1 aged 6 to 10years; group 2 aged 11 to 15years; group 3 aged 16 to 20years)...
May 31, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28595211/-closure-of-wide-patent-ductus-arteriosus-using-a-fenestrated-muscular-vsd-occluder-device-in-a-pediatric-patient-with-down-syndrome-and-pulmonary-hypertension
#11
Osman Güvenç, Murat Saygı, İbrahim Halil Demir, Ender Ödemiş
Patients with wide patent ductus arteriosus and significant pulmonary hypertension not treated in time constitute a significant problem for cardiologists. For these patients, tests that could aid in decision-making for further planning include reversibility and balloon occlusion tests performed in the catheterization laboratory. Devices developed for the closure of ductus as well as different devices with off-label use may be employed in patients scheduled for transcatheter occlusion. When result of reversibility test is borderline positive, the use of fenestrated device may be applicable for selected patients...
June 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28579695/self-powered-autonomous-biological-oxygen-demand-biosensor-for-online-water-quality-monitoring
#12
Grzegorz Pasternak, John Greenman, Ioannis Ieropoulos
Standard Biological Oxygen Demand (BOD) analysis requires 5 days to complete. To date, microbial fuel cell biosensors used as an alternative method for BOD assessment requires external apparatus, which limits their use for on-line monitoring in remote, off-grid locations. In this study, a self-powered, floating biosensor was developed for online water quality monitoring. This approach eliminated the need for external apparatus and maintenance that would otherwise be required by other techniques. The biosensor was able to detect urine in freshwater and turn ON a visual and sound cues (85 dB)...
June 2017: Sensors and Actuators. B, Chemical
https://www.readbyqxmd.com/read/28571452/miniaturized-thermocycler-based-on-thermoelectric-heating-for-diagnosis-of-sexually-transmitted-disease-by-dna-amplification
#13
Hyunjung Lim, Ga Eun Jo, Kyong Soo Kim, Seung Min Back, Hyuk Choi
Sexually transmitted disease (STD) is among the most common infectious diseases; therefore, it is necessary to develop sensitive early diagnostic techniques. As the gold standard, polymerase chain reaction (PCR) has been most widely employed for STD diagnosis; however, PCR requires large and expensive instruments. In this study, miniaturized thermal cycler using Peltier modules was developed for the PCR analysis. In comparison with the conventional PCR instrument, the Peltier-based micro-PCR (P-mPCR) device developed in this study enables one to amplify and successfully distinguish between DNA of different sizes...
May 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28554359/clinical-issues-june-2017
#14
Mary J Ogg, Esther M Johnstone
Defining a small amount of surgical smoke Key words: surgical smoke, medical-surgical vacuum system, suction tubing. Assessment of hazardous medications Key words: hazardous medications, safety data sheets, OSHA hazard communication. Documentation of electrosurgical devices Key words: electrosurgical device. Developing an explant policy Key words: explant, guideline, implant, policy.
June 2017: AORN Journal
https://www.readbyqxmd.com/read/28550299/microfluidic-isolation-of-circulating-tumor-cell-clusters-by-size-and-asymmetry
#15
Sam H Au, Jon Edd, Amy E Stoddard, Keith H K Wong, Fabio Fachin, Shyamala Maheswaran, Daniel A Haber, Shannon L Stott, Ravi Kapur, Mehmet Toner
Circulating tumor cell clusters (CTC clusters) are potent initiators of metastasis and potentially useful clinical markers for patients with cancer. Although there are numerous devices developed to isolate individual circulating tumor cells from blood, these devices are ineffective at capturing CTC clusters, incapable of separating clusters from single cells and/or cause cluster damage or dissociation during processing. The only device currently able to specifically isolate CTC clusters from single CTCs and blood cells relies on the batch immobilization of clusters onto micropillars which necessitates long residence times and causes damage to clusters during release...
May 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28479938/statistical-shape-modeling-for-cavopulmonary-assist-device-development-variability-of-vascular-graft-geometry-and-implications-for-hemodynamics
#16
Jan L Bruse, Giuliano Giusti, Catriona Baker, Elena Cervi, Tain-Yen Hsia, Andrew M Taylor, Silvia Schievano
Patients born with a single functional ventricle typically undergo three-staged surgical palliation in the first years of life, with the last stage realizing a cross-like total cavopulmonary connection (TCPC) of superior and inferior vena cavas (SVC and IVC) with both left and right pulmonary arteries, allowing all deoxygenated blood to flow passively back to the lungs (Fontan circulation). Even though within the past decades more patients survive into adulthood, the connection comes at the prize of deficiencies such as chronic systemic venous hypertension and low cardiac output, which ultimately may lead to Fontan failure...
June 2017: Journal of Medical Devices
https://www.readbyqxmd.com/read/28457656/stimulating-patient-engagement-in-medical-device-development%C3%A2-in-kidney-disease-a-report-of-a-kidney-health%C3%A2-initiative-workshop
#17
Frank P Hurst, Dolph Chianchiano, Linda Upchurch, Benjamin R Fisher, Jennifer E Flythe, Celeste Castillo Lee, Terri Hill, Carolyn Y Neuland
New technologies challenge current dialysis treatment paradigms as devices become smaller, more portable, and increasingly used outside the dialysis clinic. It is unclear how patients will view this care transition, and it will be important to consider patient and care partner perspectives during all aspects of development for novel dialysis therapies, from design and clinical trials to regulatory approval. To gain insight into this area, the Kidney Health Initiative, a public-private partnership between the American Society of Nephrology, the US Food and Drug Administration, and nearly 80 member organizations and companies dedicated to enhancing patient safety and fostering innovation in kidney disease, convened a workshop of patients, care partners, and other kidney community stakeholders...
April 27, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28446007/collaborative-efforts-among-the-fields-of-technology-device-development-and-medicine
#18
Tack Lee
No abstract text is available yet for this article.
April 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28413621/recent-advances-in-pediatric-ventilatory-assistance
#19
REVIEW
Nicolas Nardi, Guillaume Mortamet, Laurence Ducharme-Crevier, Guillaume Emeriaud, Philippe Jouvet
In this review on respiratory assistance, we aim to discuss the following recent advances: the optimization and customization of mechanical ventilation, the use of high-frequency oscillatory ventilation, and the role of noninvasive ventilation. The prevention of ventilator-induced lung injury and diaphragmatic dysfunction is now a key aspect in the management of mechanical ventilation, since these complications may lead to higher mortality and prolonged length of stay in intensive care units. Different physiological measurements, such as esophageal pressure, electrical activity of the diaphragm, and volumetric capnography, may be useful objective tools to help guide ventilator assistance...
2017: F1000Research
https://www.readbyqxmd.com/read/28394582/multiplex-paper-based-colorimetric-dna-sensor-using-pyrrolidinyl-peptide-nucleic-acid-induced-agnps-aggregation-for-detecting-mers-cov-mtb-and-hpv-oligonucleotides
#20
Prinjaporn Teengam, Weena Siangproh, Adisorn Tuantranont, Tirayut Vilaivan, Orawon Chailapakul, Charles S Henry
The development of simple fluorescent and colorimetric assays that enable point-of-care DNA and RNA detection has been a topic of significant research because of the utility of such assays in resource limited settings. The most common motifs utilize hybridization to a complementary detection strand coupled with a sensitive reporter molecule. Here, a paper-based colorimetric assay for DNA detection based on pyrrolidinyl peptide nucleic acid (acpcPNA)-induced nanoparticle aggregation is reported as an alternative to traditional colorimetric approaches...
April 27, 2017: Analytical Chemistry
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