Keisuke Toya, Yoshito Tomimaru, Shogo Kobayashi, Kiyokazu Nakajima, Akima Harada, Kazuki Sasaki, Yoshifumi Iwagami, Daisaku Yamada, Takehiro Noda, Hidenori Takahashi, Koichi Hayakawa, Isamu Matsuda, Takahiro Naka, Shigeru Miyagawa, Yuichiro Doki, Hidetoshi Eguchi
BACKGROUND: Cell-derived sheets are of global interest for regenerative therapy. Transplanting a sheet for abdominal organs requires a device for laparoscopic delivery to minimize invasiveness. Here, using a porcine model, we aimed to confirm the feasibility of a device developed to deliver sheets to the thoracic cavity in a laparoscopic transplantation procedure. MATERIAL AND METHODS: We used the device to transplant human skeletal myoblast cell sheets onto the liver and measured extra-corporeal, intra-abdominal, and total procedure times for sheet transplantation...
April 9, 2024: Minimally Invasive Therapy & Allied Technologies: MITAT