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https://www.readbyqxmd.com/read/29346727/bioinspired-pressure-tolerant-asymmetric-slippery-surface-for-continuous-self-transport-of-gas-bubbles-in-aqueous-environment
#1
Chunhui Zhang, Bo Zhang, Hongyu Ma, Zhe Li, Xiao Xiao, Yuheng Zhang, Xinyu Cui, Cunming Yu, Moyuan Cao, Lei Jiang
Bio-surfaces with geometry-gradient structures or special wettabilities demonstrate intriguing performance in manipulating the behaviors of versatile fluids. By mimicking natural species, i.e., the cactus spine with a shape-gradient morphology and the Picher plant with a lubricated inner surface, we have successfully prepared an asymmetric slippery surface by following the processes of CO2-laser cutting, superhydrophobic modification, and the fluorinert infusion. The asymmetric morphology will cause the deformation of gas bubbles and subsequently engender an asymmetric driven force on them...
January 18, 2018: ACS Nano
https://www.readbyqxmd.com/read/29346719/a-tunable-molten-salt-route-for-scalable-synthesis-of-ultrathin-amorphous-carbon-nanosheets-as-high-performance-anode-materials-for-lithium-ion-batteries
#2
Yixian Wang, Wei Tian, Luhai Wang, Haoran Zhang, Jialiang Liu, Tingyue Peng, Lei Pan, Xiaobo Wang, Mingbo Wu
Amorphous carbon is regarded as a promising alternative to commercial graphite as the lithium-ion battery anode due to its capability to reversibly store more lithium ions. However, the structural disorder with a large number of defects can lead to low electrical conductivity of the amorphous carbon, thus limiting its application for high power output. Herein, ultrathin amorphous carbon nanosheets were prepared from petroleum asphalt through tuning the carbonization temperature in a molten-salt medium. The amorphous nanostructure with expanded carbon interlayer spacing can provide substantial active sites for lithium storage while the two-dimensional (2D) morphology can facilitate fast electrical conductivity...
January 18, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29346654/evaluation-of-system-mapping-approaches-in-identifying-patient-safety-risks
#3
Mecit Can Emre Simsekler, James R Ward, P John Clarkson
Objective: While many system mapping approaches (SMAs) have been broadly used in safety-critical industries, few have so far been employed in the healthcare field to assist in the identification of patient safety risks. In this study, we evaluated a set of system modelling approaches to assess their potential contribution to the identification of risks affecting patient safety. The aim was to gain a greater understanding of the practical application of system modelling approaches with the help of the risk categorization framework developed in this study...
January 16, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29346576/commentary-on-communicating-messages-about-drinking-using-the-big-legal-guns-to-block-alcohol-health-warning-labels
#4
Paula O'Brien, Deborah Gleeson, Robin Room, Claire Wilkinson
Like the tobacco industry, the alcohol industry, with the support of governments in alcohol exporting nations, is looking to international trade and investment law as a means to oppose health warning labels on alcohol. The threat of such litigation, let alone its commencement, has the potential to deter all but the most resolute governments from implementing health warning labeling.
January 16, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29346441/a-portable-system-for-processing-donated-whole-blood-into-high-quality-components-without-centrifugation
#5
Sean C Gifford, Briony C Strachan, Hui Xia, Eszter Vörös, Kian Torabian, Taylor A Tomasino, Gary D Griffin, Benjamin Lichtiger, Fleur M Aung, Sergey S Shevkoplyas
BACKGROUND: The use of centrifugation-based approaches for processing donated blood into components is routine in the industrialized world, as disparate storage conditions require the rapid separation of 'whole blood' into distinct red blood cell (RBC), platelet, and plasma products. However, the logistical complications and potential cellular damage associated with centrifugation/apheresis manufacturing of blood products are well documented. The objective of this study was to evaluate a proof-of-concept system for whole blood processing, which does not employ electromechanical parts, is easily portable, and can be operated immediately after donation with minimal human labor...
2018: PloS One
https://www.readbyqxmd.com/read/29346402/gene-regulation-in-kluyveromyces-marxianus-in-the-context-of-chromosomes
#6
Du Toit W P Schabort, Stephanus G Kilian, James C du Preez
Eukaryotes, including the unicellular eukaryotes such as yeasts, employ multiple levels of gene regulation. Regulation of chromatin structure through chromatin compaction cascades, and influenced by transcriptional insulators, might play a role in the coordinated regulation of genes situated at adjacent loci and expressed as a co-regulated cluster. Subtelomeric gene silencing, which has previously been described in the yeast Saccharomyces cerevisiae, is an example of this phenomenon. Transcription from a common regulatory element located around a shared intergenic region is another factor that could coordinate the transcription of genes at adjacent loci...
2018: PloS One
https://www.readbyqxmd.com/read/29346343/asthma-mortality-among-persons-aged-15-64-years-by-industry-and-occupation-united-states-1999-2016
#7
Opal Patel, Girija Syamlal, John Wood, Katelynn E Dodd, Jacek M Mazurek
In 2015, an estimated 18.4 million U.S. adults had current asthma, and 3,396 adult asthma deaths were reported (1). An estimated 11%-21% of asthma deaths might be attributable to occupational exposures (2). To describe asthma mortality among persons aged 15-64 years,* CDC analyzed multiple cause-of-death data† for 1999-2016 and industry and occupation information collected from 26 states§ for the years 1999, 2003, 2004, and 2007-2012. Proportionate mortality ratios (PMRs)¶ for asthma among persons aged 15-64 years were calculated...
January 19, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29346328/comparison-of-svm-rf-and-elm-on-an-electronic-nose-for-the-intelligent-evaluation-of-paraffin-samples
#8
Hong Men, Songlin Fu, Jialin Yang, Meiqi Cheng, Yan Shi, Jingjing Liu
Paraffin odor intensity is an important quality indicator when a paraffin inspection is performed. Currently, paraffin odor level assessment is mainly dependent on an artificial sensory evaluation. In this paper, we developed a paraffin odor analysis system to classify and grade four kinds of paraffin samples. The original feature set was optimized using Principal Component Analysis (PCA) and Partial Least Squares (PLS). Support Vector Machine (SVM), Random Forest (RF), and Extreme Learning Machine (ELM) were applied to three different feature data sets for classification and level assessment of paraffin...
January 18, 2018: Sensors
https://www.readbyqxmd.com/read/29346303/micro-spherical-sulfur-graphene-oxide-composite-via-spray-drying-for-high-performance-lithium-sulfur-batteries
#9
Yuan Tian, Zhenghao Sun, Yongguang Zhang, Xin Wang, Zhumabay Bakenov, Fuxing Yin
An efficient, industry-accepted spray drying method was used to synthesize micro-spherical sulfur/graphene oxide (S/GO) composites as cathode materials within lithium sulfur batteries. The as-designed wrapping of the sulfur-nanoparticles, with wrinkled GO composites, was characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The unique morphological design of this material enabled superior discharge capacity and cycling performance, demonstrating a high initial discharge capacity of 1400 mAh g-1 at 0...
January 18, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29346297/the-dynamic-performance-of-flexural-ultrasonic-transducers
#10
Andrew Feeney, Lei Kang, George Rowlands, Steve Dixon
Flexural ultrasonic transducers are principally used as proximity sensors and for industrial metrology. Their operation relies on a piezoelectric ceramic to generate a flexing of a metallic membrane, which delivers the ultrasound signal. The performance of flexural ultrasonic transducers has been largely limited to excitation through a short voltage burst signal at a designated mechanical resonance frequency. However, a steady-state amplitude response is not generated instantaneously in a flexural ultrasonic transducer from a drive excitation signal, and differences in the drive characteristics between transmitting and receiving transducers can affect the measured response...
January 18, 2018: Sensors
https://www.readbyqxmd.com/read/29346087/a-not-for-profit-regulatory-model-for-legal-recreational-cannabis-insights-from-the-regulation-of-gaming-machine-gambling-in-new-zealand
#11
Chris Wilkins
A dozen or more regulatory frameworks have been proposed for legal cannabis but many of the "not-for-profit" options have yet to be developed in any detail, reducing the likelihood they will be seriously considered by policy makers. New Zealand's innovative "not-for-profit" regulatory regime for gaming machine gambling (i.e. "slot machines") has reversed the previous increase in gambling expenditure, empowered local councils to cap the number of gambling venues, and is unique in requiring the societies operating gaming machines to distribution 40% of the gross expenditure from machines (i...
January 12, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29346070/key-pharmacovigilance-stakeholders-experiences-of-direct-patient-reporting-of-adverse-drug-reactions-and-their-prospects-of-future-development-in-the-european-union
#12
P Inácio, A Cavaco, E Allan, M Airaksinen
OBJECTIVES: In the European Union (EU), legislation allows patients to directly report adverse drug reactions (ADRs) to competent authorities. Five years after its implementation, patient reporting is not equal in all countries. This study aimed to explore key stakeholders' perceptions of patient reporting in four EU countries. STUDY DESIGN: Qualitative study design. METHODS: Twelve representatives from national pharmacovigilance centres and/or authorities as well as national pharmaceutical industry bodies in four EU countries participated in the study...
January 12, 2018: Public Health
https://www.readbyqxmd.com/read/29346031/2016-new-horizons-lecture-beyond-imaging-radiology-of-tomorrow
#13
Hedvig Hricak
This article is based on the New Horizons lecture delivered at the 2016 Radiological Society of North America Annual Meeting. It addresses looming changes for radiology, many of which stem from the disruptive effects of the Fourth Industrial Revolution. This is an emerging era of unprecedented rapid innovation marked by the integration of diverse disciplines and technologies, including data science, machine learning, and artificial intelligence-technologies that narrow the gap between man and machine. Technologic advances and the convergence of life sciences, physical sciences, and bioengineering are creating extraordinary opportunities in diagnostic radiology, image-guided therapy, targeted radionuclide therapy, and radiology informatics, including radiologic image analysis...
January 18, 2018: Radiology
https://www.readbyqxmd.com/read/29345953/micro-to-nanoscale-engineering-of-surface-precipitates-using-reconfigurable-contact-lines
#14
Prasenjit Kabi, Swetaprovo Chaudhuri, Saptarshi Basu
Nanoscale engineering has traditionally adopted the chemical route of synthesis or opto-chemical techniques like lithography requiring large process times, expensive equipment and an inert environment. Directed self-assembly using evaporation of nanocolloidal droplet can be a potential low-cost alternative across various industries ranging from semiconductors to biomedical systems. It is relatively simple to scale and re-orient the evaporation driven internal flow field in an evaporating droplet which can direct dispersed matter into functional agglomerates...
January 18, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29345861/ruthenium-catalyzed-aerobic-oxidation-of-amines
#15
Debabrata Maiti, Goutam Kumar Lahiri, Ritwika Ray, Arijit Singha Hazari
Amine oxidation is one of the fundamental reactions in organic synthesis since it leads to a variety of value-added products like oximes, nitriles, imines and amides among many others. These products comprise the key N-containing building blocks in modern chemical industry, and such transformations when achieved in presence of molecular oxygen without using stoichiometric oxidants, are much preferred since they circumvent the production of unwanted wastes. In parallel, versatility of ruthenium catalysts in various oxidative transformations is well-documented...
January 18, 2018: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/29345746/history-of-genome-editing-in-yeast
#16
Marcin G Fraczek, Samina Naseeb, Daniela Delneri
For thousands of years humans have used the budding yeast Saccharomyces cerevisiae for production of bread and alcohol, however only for the last 30-40 years our understanding of the yeast biology has dramatically increased enabling us to modify its genome. Although S. cerevisiae has been the main focus of many research groups, other non-conventional yeasts have also been studied and exploited for biotechnological purposes. Our experiments and knowledge have evolved from recombination, to high-throughput PCR based transformations, to highly accurate CRISPR methods, in order to alter yeast traits for either research of industrial purposes...
January 18, 2018: Yeast
https://www.readbyqxmd.com/read/29345639/emergent-constraint-on-equilibrium-climate-sensitivity-from-global-temperature-variability
#17
Peter M Cox, Chris Huntingford, Mark S Williamson
Equilibrium climate sensitivity (ECS) remains one of the most important unknowns in climate change science. ECS is defined as the global mean warming that would occur if the atmospheric carbon dioxide (CO2) concentration were instantly doubled and the climate were then brought to equilibrium with that new level of CO2. Despite its rather idealized definition, ECS has continuing relevance for international climate change agreements, which are often framed in terms of stabilization of global warming relative to the pre-industrial climate...
January 17, 2018: Nature
https://www.readbyqxmd.com/read/29345593/antithrombotic-therapy-after-tavr
#18
Tobias Geisler, Michal Droppa, Karin Mueller, Oliver Borst
Transvascular aortic valve replacement (TAVR) has emerged as a treatment option in patients with severe aortic stenosis who are inoperable and has recently been evaluated in patients with intermediate surgical risk. The number of procedures is increasing worldwide in parallel with the demographic changes in industrial countries. The risk for cerebral embolism is of main concern and represents a major determinant for prognosis and quality of live after TAVR. The empiric antithrombotic therapy consists of dual antiplatelet therapy (DAPT); however the risk-benefit of this approach is lacking evidence from randomized, placebo-controlled trials regarding choice and duration of antithrombotic treatment...
January 17, 2018: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/29345546/enhanced-biosorption-of-transition-metals-by-living-chlorella-vulgaris-immobilized-in-ca-alginate-beads
#19
Ashfaq Ahmad, A H Bhat, Azizul Buang
In this study freely suspended and Ca-alginate immobilized C. vulgaris cells were used for the biosorption of Fe(II), Mn(II), and Zn(II) ions, from the aqueous solution. Experimental data showed that biosorption capacity of algal cells was strongly dependent on the operational condition such as pH, initial metal ions concentration, dosages, contact time and temperature. The maximum biosorption of Fe(II) 43.43, Mn(II) 40.98 and Zn(II) 37.43 mg/g was achieved with Ca-alginate immobilized algal cells at optimum pH of 6...
January 18, 2018: Environmental Technology
https://www.readbyqxmd.com/read/29345538/real-time-monitoring-of-nanoscale-tio2-concentration-by-spectrophotometry-implications-of-agglomeration-due-to-natural-organic-matter-and-multivalent-ions
#20
Andrew B Holmes, Frank X Gu
The study of the environmental fate of nanoscale TiO2 (n-TiO2) is a major recent research focus which requires a rapid and accurate on-site concentration determination method. Inductively coupled plasma mass spectroscopy (ICP-MS) has been the most widely used method for determining the concentration of n-TiO2 in environmental samples; however, poses many challenges, such as hazardous hydrofluoric acid pre-treatment and clear limitations in mobile on-site measurement and monitoring. This study demonstrates that industrial wastewater containing natural organic matter (NOM) can present a major challenge to the analysis of n-TiO2 by ICP-MS, and introduces a spectrophotometry technique that can be used as an alternative...
January 18, 2018: Environmental Technology
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