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https://www.readbyqxmd.com/read/28324855/impacts-of-local-circulations-on-the-wintertime-air-pollution-in-the-guanzhong-basin-china
#1
Naifang Bei, Linna Zhao, Bo Xiao, Ning Meng, Tian Feng
Urbanization and industrialization in the recent 30years have caused frequent heavy haze pollution in the Guanzhong basin, China during wintertime. Based on the categorized large-scale synoptic situations, the local circulation and its impact on the air pollution in the basin have been investigated using observational data analyses and model simulations with the WRF-CHEM model. The simulated mountain-valley breeze circulations are well established under most of the large-scale synoptic situations in the south-north direction...
March 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28324687/variation-of-natural-radionuclides-in-non-ferrous-fayalite-slags-during-a-one-month-production-period
#2
Tom Croymans, Indy Vandael Schreurs, Mikael Hult, Gerd Marissens, Guillaume Lutter, Heiko Stroh, Sonja Schreurs, Wouter Schroeyers
The European Basic Safety Standards (EU-BSS) describes a set of NORM (Naturally Occurring Radioactive Material)-processing industries which produce residues known to be possibly enriched in NORs (Naturally Occurring Radionuclides). These residues can be used as a component in building materials aimed for public usage. The industrial processes, in which the residues are produced, are often complex and total monitoring can be challenging especially when the origin of the used raw materials varies. In this study the NORs present in non-ferrous fayalite slags of a secondary smelter facility, a NORM-processing industry according to the EU-BSS, were monitored daily during a one-month production period...
March 18, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28324650/genome-engineering-of-virulent-lactococcal-phages-using-crispr-cas9
#3
Marie-Laurence Lemay, Denise M Tremblay, Sylvain Moineau
Phages are biological entities found in every ecosystem. Although much has been learned about them in past decades, significant knowledge gaps remain. Manipulating virulent phage genomes is challenging. To date, no efficient gene-editing tools exist for engineering virulent lactococcal phages. Lactococcus lactis is a bacterium extensively used as a starter culture in various milk fermentation processes and its phage sensitivity poses a constant risk to the cheese industry. The lactococcal phage p2 is one of the best-studied models for these virulent phages...
March 21, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28324594/polymers-in-the-delivery-of-sirna-for-the-treatment-of-virus-infections
#4
REVIEW
Nicholas Reynolds, Megan Dearnley, Tracey M Hinton
Viral diseases remain a major cause of death worldwide. Despite advances in vaccine and antiviral drug technology, each year over three million people die from a range of viral infections. Predominant viruses include human immunodeficiency virus, hepatitis viruses, and gastrointestinal and respiratory viruses. Now more than ever, robust, easily mobilised and cost-effective antiviral strategies are needed to combat both known and emerging disease threats. RNA interference and small interfering (si)RNAs were initially hailed as a "magic bullet", due to their ability to inhibit the synthesis of any protein via the degradation of its complementary messenger RNA sequence...
April 2017: Topics in Current Chemistry (Journal)
https://www.readbyqxmd.com/read/28324254/pilot-testing-model-to-uncover-industrial-symbiosis-in-brazilian-industrial-clusters
#5
Adriana Valélia Saraceni, Luis Mauricio Resende, Pedro Paulo de Andrade Júnior, Joseane Pontes
The main objective of this study was to create a pilot model to uncover industrial symbiosis practices in Brazilian industrial clusters. For this purpose, a systematic revision was conducted in journals selected from two categories of the ISI Web of Knowledge: Engineering, Environmental and Engineering, Industrial. After an in-depth revision of literature, results allowed the creation of an analysis structure. A methodology based on fuzzy logic was applied and used to attribute the weights of industrial symbiosis variables...
March 21, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28324250/erratum-to-modeling-of-air-pollutant-concentrations-in-an-industrial-region-of-turkey
#6
Gizem Tuna Tuygun, Hicran Altuğ, Tolga Elbir, Eftade E Gaga
No abstract text is available yet for this article.
March 21, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28324068/bisphenol-a-exposure-ovarian-follicle-numbers-and-female-sex-steroid-hormone-levels-results-from-a-clarity-bpa-study
#7
Shreya Patel, Emily Brehm, Liying Gao, Saniya Rattan, Ayelet Ziv-Gal, Jodi A Flaws
Bisphenol A (BPA) is an industrial chemical found in thermal receipts, and food and beverage containers. Previous studies have shown that BPA can affect the numbers and health of ovarian follicles and the production of sex steroid hormones, but they often did not include a wide-range of doses of BPA, used a small sample size, focused on relatively short-term exposures to BPA, and/or did not examine the consequences of chronic BPA exposure on the ovaries or steroid levels. Thus, this study was designed to examine the effects of a wide range of doses of BPA on ovarian morphology and sex steroid hormone production...
March 16, 2017: Endocrinology
https://www.readbyqxmd.com/read/28323840/htc-vive-mevislab-integration-via-openvr-for-medical-applications
#8
Jan Egger, Markus Gall, Jürgen Wallner, Pedro Boechat, Alexander Hann, Xing Li, Xiaojun Chen, Dieter Schmalstieg
Virtual Reality, an immersive technology that replicates an environment via computer-simulated reality, gets a lot of attention in the entertainment industry. However, VR has also great potential in other areas, like the medical domain, Examples are intervention planning, training and simulation. This is especially of use in medical operations, where an aesthetic outcome is important, like for facial surgeries. Alas, importing medical data into Virtual Reality devices is not necessarily trivial, in particular, when a direct connection to a proprietary application is desired...
2017: PloS One
https://www.readbyqxmd.com/read/28323727/experience-with-the-use-of-single-use-disposable-bronchoscope-in-the-icu-in-a-tertiary-referral-center-of-singapore
#9
Dominic C Marshall, Rucha S Dagaonkar, Chan Yeow, Anura T Peters, Siew Kin Tan, Dessmon Y H Tai, Soon Keng Gohs, Albert Y H Lim, Benjamin Ho, Sennen J W Lew, John Abisheganaden, Akash Verma
BACKGROUND: Flexible bronchoscopy is performed frequently in intensive care units (ICUs) for various indications using the reusable conventional bronchoscope (CB). Recently, "single-use disposable bronchoscope" (SB) was introduced into the health care industry. The purpose of this study was to compare the utility of SB with CB in ICU. METHODS: A retrospective review of medical records of patients undergoing flexible bronchoscopy in the ICUs in the year 2015. RESULTS: Ninety-three patients undergoing flexible bronchoscopy in the ICU were studied...
April 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28323608/from-doctors-stories-to-doctors-stories-and-back-again
#10
Marcia Day Childress
Stories have always been central to medicine, but during the twentieth century bioscience all but eclipsed narrative's presence in medical practice. In Doctors' Stories, published in 1991, Kathryn Montgomery excavated medicine's narrative foundations and functions to reveal new possibilities for how to conceive and characterize medicine. Physicians' engagement with stories has since flourished, especially through the narrative medicine movement, although in the twenty-first century this has been challenged by the health care industry's business-minded and data-driven clinical systems...
March 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28323494/associations-between-thematic-content-and-industry-self-regulation-code-violations-in-beer-advertising-broadcast-during-the-u-s-ncaa-basketball-tournament
#11
Jonathan K Noel, Ziming Xuan, Thomas F Babor
BACKGROUND: Beer marketing in the United States is controlled through self-regulation, whereby the beer industry has created a marketing code and enforces its use. We performed a thematic content analysis on beer ads broadcast during a U.S. college athletic event and determined which themes are associated with violations of a self-regulated alcohol marketing code. METHODS: 289 beer ads broadcast during the U.S. NCAA Men's and Women's 1999-2008 basketball tournaments were assessed for the presence of 23 thematic content areas...
March 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28323424/toward-a-comprehensive-global-emission-inventory-of-c4-c10-perfluoroalkane-sulfonic-acids-pfsas-and-related-precursors-focus-on-the-life-cycle-of-c8-based-products-and-ongoing-industrial-transition
#12
Zhanyun Wang, Justin M Boucher, Martin Scheringer, Ian T Cousins, Konrad Hungerbuehler
Here a new global emission inventory of C4-C10 perfluoroalkanesulfonic acids (PFSAs) from the life cycle of perfluorooctanesulfonyl fluoride (POSF)-based products in 1958-2030 is presented. In particular, we substantially improve and expand the previous frameworks by incorporating missing pieces (e.g., emissions to soil through land treatment, overlooked precursors) and updating parameters (e.g., emission factors, degradation half-lives). In 1958-2015, total direct and indirect emissions of perfluorooctanesulfonic acid (PFOS) are estimated as 1228-4930 tonnes, and emissions of PFOS precursors are estimated as 1230-8738 and approximately 670 tonnes for x-perfluorooctanesulfonamides/sulfonamido ethanols (xFOSA/Es) and POSF, respectively...
March 21, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28319996/oral-direct-acting-agent-therapy-for-hepatitis-c-virus-infection-a-systematic-review
#13
Oluwaseun Falade-Nwulia, Catalina Suarez-Cuervo, David R Nelson, Michael W Fried, Jodi B Segal, Mark S Sulkowski
Background: Rapid improvements in hepatitis C virus (HCV) therapy have led to the approval of multiple oral direct-acting antiviral (DAA) regimens by the U.S. Food and Drug Administration (FDA) for treatment of chronic HCV infection. Purpose: To summarize published literature on the efficacy and safety of oral DAAs for treatment of persons with chronic HCV infection. Data Sources: MEDLINE and EMBASE from inception through 1 November 2016. Study Selection: 42 English-language studies from controlled and single-group registered clinical trials of adults with HCV infection that evaluated at least 8 weeks of an FDA-approved interferon-free HCV regimen that included at least 2 DAAs...
March 21, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28319940/iron-status-of-vegetarian-children-a-review-of-literature
#14
Roman Pawlak, Kami Bell
BACKGROUND: Iron is considered a nutrient of concern for vegetarians. In children, inadequate iron status may lead to anemia and poor growth. SUMMARY: Thirteen original manuscripts met the inclusion criteria. Various biochemical markers of iron status, such as hemoglobin (Hb) and serum ferritin, were used. Seven of the 13 studies reported the prevalence of iron deficiency separately for vegetarians and non-vegetarians. Five out of 7 showed a higher prevalence of iron deficiency among the vegetarian participants, while the other 2 showed a higher prevalence of iron deficiency among non-vegetarians...
March 21, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28319906/functional-characterization-of-gram-negative-bacteria-from-different-genera-as-multiplex-cadmium-biosensors
#15
Lara Bereza-Malcolm, Sanja Aracic, Ruban Kannan, Gülay Mann, Ashley E Franks
Widespread presence of cadmium in soil and water systems is a consequence of industrial and agricultural processes. Subsequent accumulation of cadmium in food and drinking water can result in accidental consumption of dangerous concentrations. As such, cadmium environmental contamination poses a significant threat to human health. Development of microbial biosensors, as a novel alternative method for in situ cadmium detection, may reduce human exposure by complementing traditional analytical methods. In this study, a multiplex cadmium biosensing construct was assembled by cloning a single-output cadmium biosensor element, cadRgfp, and a constitutively expressed mrfp1 onto a broad-host range vector...
March 16, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28319884/sodium-chlorate-induces-dna-damage-and-dna-protein-cross-linking-in-rat-intestine-a-dose-dependent-study
#16
Shaikh Nisar Ali, Fariheen Aisha Ansari, Hussain Arif, Riaz Mahmood
Sodium chlorate (NaClO3) is widely used in paper and pulp industries and as a non-selective herbicide. It is also a major by-product generated upon disinfection of drinking water by chlorine dioxide. In this study, we have investigated the genotoxicity of NaClO3 on the small intestine of rats. Adult male rats were divided into 5 groups: one control and four NaClO3 treated groups. The NaClO3 treated groups were given a single acute oral dose of NaClO3 (100, 250, 500 and 750 mg/kg body weight) and sacrificed 24 h later...
March 8, 2017: Chemosphere
https://www.readbyqxmd.com/read/28319819/childhood-cancer-in-small-geographical-areas-and-proximity-to-air-polluting-industries
#17
Juan A Ortega-García, Fernando A López-Hernández, Alberto Cárceles-Álvarez, José L Fuster-Soler, Diana I Sotomayor, Rebeca Ramis
AIM: Pediatric cancer has been associated with exposure to certain environmental carcinogens. The purpose of this work is to analyse the relationship between environmental pollution and pediatric cancer risk. METHOD: We analysed all incidences of pediatric cancer (<15) diagnosed in a Spanish region during the period 1998-2015. The place of residence of each patient and the exact geographical coordinates of main industrial facilities was codified in order to analyse the spatial distribution of cases of cancer in relation to industrial areas...
March 16, 2017: Environmental Research
https://www.readbyqxmd.com/read/28319783/development-of-an-evaluation-framework-for-publicly-funded-r-d-projects-the-case-of-korea-s-next-generation-network
#18
Eungdo Kim, Soyoung Kim, Hongbum Kim
For decades, efforts have been made globally to measure the performance of large-scale public projects and to develop a framework to perform such measurements due to the complexity and dynamics of R&D and stakeholder interests. Still, limitations such as the use of a simply modified model and the lack of a comprehensive viewpoint are prevalent in existing approaches. In light of these research gaps, this study suggests a practical model to evaluate the performance of large-scale and publicly funded projects...
February 28, 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28319722/bisphenol-s-exposure-modulate-macrophage-phenotype-as-defined-by-cytokines-profiling-global-metabolomics-and-lipidomics-analysis
#19
Chao Zhao, Zhi Tang, Jiacheng Yan, Jing Fang, Hailin Wang, Zongwei Cai
As an important structural analogue of bisphenol A (BPA), bisphenol S (BPS) has been used as alternatives to BPA in industrialized production. However, the immunotoxicity of BPS remains poorly understood. As a critical model in inflammatory responses, macrophages are used to explore the immunotoxic potential and mechanisms of BPS at environmentally relevant concentrations in our study. Here, we are combining molecular toxicology and mass spectrometry (MS)-based global metabolomics and lipidomics study together to estimate the variation of cytokines profiling and metabolism characteristic following BPS exposure...
March 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28319397/a-scalable-platform-for-structured-and-hybrid-soft-nanocolloids-by-continuous-precipitation-in-a-confined-environment
#20
Victoria E Lee, Chris Sosa, Rui Liu, Robert K Prud'homme, Rodney D Priestley
Geometrically-structured polymer nanocolloids, including Janus nanocolloids, have been widely investigated for their unique properties, which are derived from their anisotropy. Controlled surface decoration with inorganic nanoparticles could induce another level of functionality into structured nanocolloids that could enable applications in fields ranging from re-writeable electronics to biphasic catalysis. Here, we demonstrate Flash NanoPrecipitation (FNP), as a one-step and scalable process platform to manufacture hybrid polymer-inorganic nanocolloids in which one phase is selectively decorated with a metal nanocatalyst by tuning the molecular interactions between the feed ingredients during the process...
March 20, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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