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Prescribing patterns

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https://www.readbyqxmd.com/read/29785585/poisoning-associated-with-inappropriate-use-of-a-eutectic-mixture-of-lidocaine-and-prilocaine-before-laser-assisted-hair-removal-about-3-cases
#1
Weniko Caré, Islam-Amine Larabi, Jérôme Langrand, Chantal Medernach, Jean-Claude Alvarez, Antoine Villa
BACKGROUND: Eutectic mixtures of lidocaine and prilocaine are used during painful dermatological procedures. Poisoning is rarely reported in adults. MATERIAL AND METHOD: We report three cases of women who experienced lidocaine and prilocaine poisoning after laser-assisted hair removal. Plasma levels of local anesthetics were assayed by a fully validated liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) method. CASE REPORTS: The rules of application of the anesthetic cream were observed apart from the maximum dose and/or maximum surface area...
May 21, 2018: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29785101/exacerbation-recovery-patterns-in-newly-diagnosed-or-maintenance-treatment-na%C3%A3-ve-patients-with-copd-secondary-analyses-of-ticari-1-trial-data
#2
David M Mannino, Emmanuelle M Clerisme-Beaty, Joanne Franceschina, Naitee Ting, Nancy K Leidy
Background: Little is known about the recovery patterns from acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in newly diagnosed or maintenance treatment-naïve patients with COPD. This study describes the course of AECOPD in these patients at the time of treatment for the symptoms of acute respiratory tract infection (RTI). Methods: This study was a secondary analysis of data from a 12-week, randomized clinical trial (TICARI 1) testing the efficacy and safety of once-daily tiotropium 18 µg maintenance therapy versus placebo in newly diagnosed or maintenance treatment-naïve COPD patients with acute RTI symptoms for ≤7 days...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29781721/current-prescription-status-of-antihypertensive-drugs-in-japanese-patients-with-hypertension-analysis-by-type-of-comorbidities
#3
Takayuki Ishida, Akinori Oh, Shinzo Hiroi, Yukio Shimasaki, Takuya Tsuchihashi
In 2014, the Japanese Society of Hypertension (JSH) issued revised guidelines for hypertension management. To assess adherence to the guidelines, this retrospective study evaluated the real-world status of antihypertensive drug prescribing for Japanese patients with hypertension, classified by comorbidity: diabetes mellitus, dyslipidemia, gout/hyperuricemia and renal diseases. Data on 59,867 hypertensive patients who received their first prescription for antihypertensive therapy between April 2014 and March 2015, were obtained from a medical insurance claims database for hospitals participating in the Diagnosis Procedure Combination/Per-Diem payment system...
May 21, 2018: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/29781284/opioid-prescription-among-sinus-surgeons
#4
Khashayar Arianpour, Brandon Nguyen, Brian Yuhan, Peter F Svider, Jean Anderson Eloy, Adam J Folbe
Background Misuse and diversion of opioids have contributed to the U.S. opioid crisis, making an understanding of specialty-specific and procedure-specific trends essential. Objective The objective of this analysis was to evaluate nationwide trends in opioid prescribing patterns among sinus surgeons performing functional endoscopic sinus surgery and maxillary sinus balloon dilation, specifically examining factors associated with variations. Methods High-volume sinus surgeons were identified through the Centers for Medicare and Medicaid Services database and cross-referenced against prescriptions to Medicare Part D beneficiaries during 2013 through 2015...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29778587/the-politics-of-place-presidential-voting-patterns-and-providers-prescription-of-emergency-contraception
#5
Kelly Cleland, Brandon Wagner, Pelin Batur, Megan McNamara, Justine Wu, Michael B Rothberg
OBJECTIVE: The most effective forms of emergency contraception (EC) require a prescription or a medical procedure; therefore, provider willingness to offer EC remains critical to patient access. This study seeks to assess whether political alignment of a provider's county is associated with provider attitudes and behaviors regarding EC. STUDY DESIGN: We analyzed survey data collected from 1313 healthcare providers from February 2013 to April 2014 at 14 academic medical centers in the United States...
May 17, 2018: Contraception
https://www.readbyqxmd.com/read/29777388/a-retrospective-study-of-opioid-prescribing-patterns-at-hospital-discharge-in-surgical-patients-with-obstructive-sleep-apnea
#6
Samir M Kendale, Jing Wang, Jeanna D Blitz, Steven Calvino, Germaine Cuff, Nicholas Barone, Andrew D Rosenberg, Lisa Doan
PURPOSE: Obstructive sleep apnea (OSA) is a risk factor for complications with postoperative opioid use, and in those patients with known or suspected OSA, minimization of postoperative opioids is recommended. We hypothesize that despite these recommendations, surgical patients with known or suspected OSA are prescribed postoperative opioids at hospital discharge at similar doses to those without OSA. METHODS: This was a retrospective analysis of the electronic health records of surgical patients from 1 November 2016 to 30 April 2017 at a single academic institution...
May 18, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29772034/three-dimensional-analysis-of-internal-adaptations-of-crowns-cast-from-resin-patterns-fabricated-using-computer-aided-design-computer-assisted-manufacturing-technologies
#7
Yushu Liu, Hongqiang Ye, Yong Wang, Yijao Zhao, Yuchun Sun, Yongsheng Zhou
PURPOSE: To evaluate the internal adaptations of cast crowns made from resin patterns produced using three different computer-aided design/computer-assisted manufacturing technologies. MATERIALS AND METHODS: A full-crown abutment made of zirconia was digitized using an intraoral scanner, and the design of the crown was finished on the digital model. Resin patterns were fabricated using a fused deposition modeling (FDM) 3D printer (LT group), a digital light projection (DLP) 3D printer (EV group), or a five-axis milling machine (ZT group)...
May 17, 2018: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/29770717/treatment-patterns-and-health-care-resource-utilization-and-costs-in-heavy-menstrual-bleeding-a-japanese-claims-database-analysis
#8
Sayako Akiyama, Erika Tanaka, Olivier Cristeau, Yoshie Onishi, Yutaka Osuga
AIMS: Heavy menstrual bleeding (HMB) is a highly prevalent condition characterized by excessive menstrual blood loss and cramping that interferes with activities of daily life. The aim of our study was to investigate treatment patterns in HMB in Japan, and to assess healthcare resource utilization and costs among women newly diagnosed with the condition. MATERIALS AND METHODS: We retrospectively analysed health insurance data available in the Japan Medical Data Center (JMDC) database on women aged 18-49 years who were newly diagnosed with primary or secondary HMB...
May 17, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29768417/what-are-the-implications-for-practice-that-arise-from-studies-of-medication-taking-a-systematic-review-of-qualitative-research
#9
Mohammed Ahmed Rashid, Nadia Llanwarne, Natalie Heyns, Fiona Walter, Jonathan Mant
BACKGROUND: Despite several decades of evidence supporting the benefits of taking medications in various diseases and healthcare settings, a significant proportion of prescribed treatments are not taken. This review sought to synthesise qualitative research exploring experiences of medication taking around the world, and to determine whether there were consistent messages arising from these studies. METHODS AND FINDINGS: 5 databases (MEDLINE, PsycINFO, EMBASE, SCOPUS, CINAHL) were systematically searched to identify published research papers using qualitative methodologies, which explored medication-taking experiences in patients, citizens, carers, relatives and clinicians...
2018: PloS One
https://www.readbyqxmd.com/read/29764875/efficacy-and-safety-of-ghx02-in-the-treatment-of-acute-bronchitis-protocol-of-a-phase-ii-double-blind-randomised-placebo-controlled-trial
#10
Yee Ran Lyu, Won-Kyung Yang, So Jung Park, Seung-Hyeong Kim, Wee-Chang Kang, In Chul Jung, Yang Chun Park
INTRODUCTION: Acute bronchitis is a self-limiting infection of the large airways; cough is the primary symptom, usually lasting for about 3 weeks. Annually, approximately 5% of adults develop acute bronchitis, and its economic burden is substantial. There are also problems of antibiotic abuse in public health systems and symptomatic therapies are commonly prescribed, for which there is insufficient supporting evidence. GHX02 contains four herbs originating from gwaruhaengryeon-hwan, which has been used in the treatment of patients with acute bronchitis in Korea...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29764635/ten-year-experience-with-student-pharmacist-research-within-a-health-system-and-education-center
#11
Elizabeth Landrum Michalets, Charlene Williams, Irene Park
INTRODUCTION: Skills gained from research experience allow student pharmacists to evolve as practitioners, innovators and perpetual learners in an increasingly complex healthcare environment. Data published regarding pharmacy resident research are focused on external dissemination rates and research programs. Little is published regarding student research. METHODS: This descriptive study was a five-year before and after comparison between the existing co-curricular model and a new longitudinal, 12-month research advanced pharmacy practice experience (L-APPE) model for student pharmacist research...
March 2018: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29761577/polypharmacy-and-psychotropic-drug-loading-in-patients-with-schizophrenia-in-asian-countries-the-reap-ap4-study
#12
Shu-Yu Yang, Lian-Yu Chen, Eunice Najoan, Roy Abraham Kallivayalil, Kittisak Viboonma, Ruzita Jamaluddin, Afzal Javed, Duong Thi Quynh Hoa, Hitoshi Iida, Kang Sim, Thiha Swe, Yan-Ling He, Yongchon Park, Helal Uddin Ahmed, Angelo De Alwis, Helen Fung-Kum Chiu, Norman Sartorius, Chay-Hoon Tan, Mian-Yoon Chong, Naotaka Shinfuku, Shih-Ku Lin
AIM: The aim of the present study was to survey the prevalence of antipsychotic polypharmacy and combined medication use across 15 Asian countries and areas in 2016. METHODS: By using the results from the fourth survey of Research on Asian Prescription Patterns on antipsychotics (REAP-AP4), the rates of polypharmacy and combined medication use in each country were analyzed. Daily medications prescribed for the treatment of inpatients or outpatients with schizophrenia, including antipsychotics, mood stabilizers, anxiolytics, hypnotics, and antiparkinson agents, were collected...
May 14, 2018: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29760590/evaluation-of-high-grade-astrocytoma-recurrence-patterns-after-radiotherapy-in-the-era-of-temozolomide-a-single-institution-experience
#13
Arno Lotar Cordova, Taynná Vernalha Rocha Almeida, Cintia Mara da Silva, Pedro Argolo Piedade, Cristiane Maria Almeida, Carlos Genesio Bezzera Lima, Carolina Dutra, Rafael Martins Ferreira, Marcelo Neves Linhares, Valeriy Denyak
Aim: Evaluating the recurrence patterns of high-grade astrocytomas in patients who were treated with radiotherapy (RT) plus temozolomide (TMZ). Background: The current literature suggests that reducing the margins added to the CTV does not significantly change the risk of recurrence and overall survival; thus, we decided to analyze our data and to examine the possibility of changing the adopted margins. Materials and methods: From February 2008 till September 2013, 55 patients were treated for high-grade astrocytomas, 20 patients who had been confirmed to have recurrence were selected for the present study...
May 2018: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/29760569/concomitant-use-of-opioid-medications-with-triptans-or-serotonergic-antidepressants-in-us-office-based-physician-visits
#14
Kyle C Molina, Kathleen A Fairman, David A Sclar
Background: Opioids are not recommended for routine treatment of migraine because their benefits are outweighed by risks of medication overuse headache and abuse/dependence. A March 2016 US Food and Drug Administration (FDA) safety communication warned of the risk of serotonin syndrome from using opioids concomitantly with 5-hydroxytryptamine receptor agonists (triptans) or serotonergic antidepressants: selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs)...
2018: Drug, Healthcare and Patient Safety
https://www.readbyqxmd.com/read/29759019/reported-adverse-drug-reactions-during-the-use-of-corticosteroids-in-a-tertiary-care-hospital
#15
Sarika Paradkar
BACKGROUND: Corticosteroids have been used in numerous medical conditions. Studying the pattern and causality of adverse drug reactions (ADRs) helps us gain greater insight into their prevention, detection, assessment, and treatment. This reduces cost of health care and increases compliance. The study aimed to evaluate the ADRs reported in patients receiving corticosteroids for age, type of reaction, duration of steroid therapy, treatment prescribed for the ADR, and causal relationship of the ADR with the prescribed steroid...
January 1, 2018: Therapeutic Innovation & Regulatory Science
https://www.readbyqxmd.com/read/29757036/determinants-of-antibiotics-prescribing-among-doctors-in-a-nigerian-urban-tertiary-hospital
#16
Olayinka O Ogunleye, Joseph O Fadare, Adesola F Yinka-Ogunleye, Bene D Anand Paramadhas, Brian Godman
BACKGROUND AND OBJECTIVE: The problem of antimicrobial resistance (AMR) has assumed pandemic dimensions especially among low and middle-income countries such as Nigeria. Irrational use of currently available antimicrobial agents is a major contributory factor. There remains a paucity of documented information on the determinants of antibiotics prescribing among physicians in Nigeria to guide future strategies to reduce AMR. This study therefore aimed to investigate the patterns and determinants of antibiotics prescription among doctors in a tertiary hospital in Nigeria as the first step to improve future antibiotic use in hospitals...
May 14, 2018: Hospital Practice (Minneapolis)
https://www.readbyqxmd.com/read/29756534/neurostimulant-prescribing-patterns-in-children-admitted-to-the-icu-after-traumatic-brain-injury
#17
Amanda Marie Morrison, Amy Houtrow, James Zullo, Patrick M Kochanek, Carol Vetterly, Ericka L Fink
Neurostimulant medications are commonly prescribed following traumatic brain injury (TBI) in adults; little is known about their use in children with TBI. Our objective was to analyze neurostimulant prescribing practices from 2005 to 2015 in children admitted to the intensive care unit (ICU) with TBI. We hypothesized that neurostimulant prescriptions have increased over time and are associated with older age and injury severity. A retrospective cohort study of patients aged 1 month to 18 years with an ICD-9-CM discharge diagnosis code for TBI admitted to the ICU between 2005 and 2015 in 37 pediatric hospitals included in the Pediatric Health Information System was conducted...
May 14, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29756393/opioid-prescribing-practices-in-patients-undergoing-surgery-for-oral-cavity-cancer
#18
John Pang, Kathryn R Tringale, Viridiana J Tapia, Bharat A Panuganti, Jesse R Qualliotine, Aria Jafari, Sunny J Haft, Lawrence S Friedman, Timothy Furnish, Kevin T Brumund, Joseph A Califano, Charles S Coffey
OBJECTIVES: Opioids have been overprescribed after general and orthopedic surgeries, but prescribing patterns have not been reported for head and neck surgery. The objectives of this retrospective review are to describe postoperative opioid prescriptions after oral cancer surgery and determine which patients receive higher amounts. METHODS: A single institution retrospective review was performed for 81 adults with oral cavity tumors undergoing surgery. Opioid prescriptions upon discharge were reported in daily oral morphine equivalents (OME)...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29756071/improving-the-quality-of-physical-health-monitoring-in-camhs-for-children-and-adolescents-prescribed-medication-for-adhd
#19
Cristal Oxley, Omer S Moghraby, Rani Samuel, Dan W Joyce
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterised by a persistent, pervasive pattern of inattention, impulsivity and hyperactivity. Stimulant medication such as methylphenidate has an established evidence base in the treatment of children and adolescents with ADHD. However, it is also associated with a risk of side effects which may include decreased appetite, increased blood pressure and possible reduced growth. Monitoring physical health in children and adolescents prescribed medication for ADHD is a key clinical responsibility and includes a number of parameters as outlined in the National Institute for Health and Care Excellence Guidelines...
2018: BMJ Open Quality
https://www.readbyqxmd.com/read/29755999/prescribing-pattern-and-prescription-writing-quality-of-antineoplastic-agents-in-the-capital-city-of-a-middle-income-developing-country
#20
Maryam Taghizadeh-Ghehi, Asiyeh Amouei, Ava Mansouri, Aarefeh Jafarzadeh Kohneloo, Molouk Hadjibabaie
Objective: Cancer is a global health concern with growing incidence worldwide. Chemotherapy is the main treatment modality in many malignancies. This study aimed at evaluation of antineoplastic prescribing pattern and prescription-writing quality in the capital city of Iran. Methods: All dispensed chemotherapy prescriptions by four main authorized pharmacies in Tehran during 1 month were targeted. Prescriptions with no antineoplastic medications or written by specialties other than oncology-related fields were excluded from the study...
January 2018: Journal of Research in Pharmacy Practice
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