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https://www.readbyqxmd.com/read/27908772/anaplasma-platys-in-dogs-from-uruguay
#1
Luis Carvalho, Maria Teresa Armua-Fernandez, Nicolás Sosa, María Laura Félix, José Manuel Venzal
Anaplasmataceae family members include vector-borne bacteria of veterinary importance that may also affect humans. Ehrlichia canis and Anaplasma platys are the main members of this family detected in dogs worldwide. In Uruguay there are not many published studies on tick-borne pathogens affecting dogs, the only haemoparasite molecularly confirmed in dogs, is the piroplasm Rangelia vitalii. The aim of the present work was to detect the presence of A. platys and E. canis in dogs and dogs-associated ticks of two localities in Northwestern Uruguay...
November 17, 2016: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/27907059/quantitative-and-selective-analysis-of-feline-growth-related-proteins-using-parallel-reaction-monitoring-high-resolution-mass-spectrometry
#2
Mårten Sundberg, Emma M Strage, Jonas Bergquist, Bodil S Holst, Margareta Ramström
Today immunoassays are widely used in veterinary medicine, but lack of species specific assays often necessitates the use of assays developed for human applications. Mass spectrometry (MS) is an attractive alternative due to high specificity and versatility, allowing for species-independent analysis. Targeted MS-based quantification methods are valuable complements to large scale shotgun analysis. A method referred to as parallel reaction monitoring (PRM), implemented on Orbitrap MS, has lately been presented as an excellent alternative to more traditional selected reaction monitoring/multiple reaction monitoring (SRM/MRM) methods...
2016: PloS One
https://www.readbyqxmd.com/read/27905278/seroprevalence-of-canine-leishmaniasis-in-northern-cyprus
#3
Tayfun Çanakçı, Arif Kurtdede, Serdar Paşa, Seray Töz Özensoy, Yusuf Özbel
OBJECTIVE: Canine leishmaniasis (CanL) is an important public and veterinary health problem in Mediterranean Basin countries. In this study, we aimed to determine the seroprevalence of CanL in several provinces of Northern Cyprus. METHODS: The seroprevalence of CanL was determined by the indirect fluorescent antibody (IFA) test in dog sera. In total, 281 dogs were randomly selected from Nicosia (n=80), Trikomo (n=58), Famagusta (n=60), Morphou (n=30), and Kyrenia (n=53), consistent with a statistically representative number of the regional dog population...
September 2016: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/27903939/nature-and-governance-of-veterinary-clinical-research-conducted-in-the-uk
#4
P Fordyce, S Mullan
In order to quantify the amount of clinical research conducted on client-owned animals under the Veterinary Surgeons Act 1966, and the nature and extent of any ethical review of that research, a questionnaire was sent to 6 UK veterinary schools, 1 charity veterinary clinic and 12 private referral clinics. The questionnaire examined whether and how much clinical research respondents undertook, and the composition of any ethical review panels examining research proposals. The questionnaire revealed a substantial amount of clinical research was conducted in the UK, with over 200 veterinary surgeons involved in the year of the survey, with at least 170 academic papers involving clinical research published by respondents in the same year...
November 30, 2016: Veterinary Record
https://www.readbyqxmd.com/read/27903326/characterizing-areas-of-potential-human-exposure-to-eastern-equine-encephalitis-virus-using-serological-and-clinical-data-from-horses
#5
J-P Rocheleau, J Arsenault, N H Ogden, L R Lindsay, M Drebot, P Michel
Eastern equine encephalitis (EEE) is a rare but severe emerging vector-borne disease affecting human and animal populations in the northeastern United States where it is endemic. Key knowledge gaps remain about the epidemiology of EEE virus (EEEV) in areas where its emergence has more recently been reported. In Eastern Canada, viral activity has been recorded in mosquitoes and horses throughout the 2000s but cases of EEEV in humans have not been reported so far. This study was designed to provide an assessment of possible EEEV human exposure by modelling environmental risk factors for EEEV in horses, identifying high-risk environments and mapping risk in the province of Quebec, Canada...
December 1, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27902902/history-of-the-first-generation-marek-s-disease-vaccines-the-science-and-little-known-facts
#6
Karel A Schat
Shortly after the isolation of Marek's disease (MD) herpesvirus (MDV) in the late 1960s vaccines were developed in England, the United States, and The Netherlands. Biggs and associates at the Houghton Poultry Research Station (HPRS) in England attenuated HPRS-16, the first cell-culture-isolated MDV strain, by passaging HPRS-16 in chick kidney cells. Although HPRS-16/Att was the first commercially available vaccine, it never became widely used and was soon replaced by the FC126 strain of herpesvirus of turkeys (HVT) vaccine developed by Witter and associates at the Regional Poultry Research Laboratory (now Avian Disease and Oncology Laboratory [ADOL]) in East Lansing, MI...
December 2016: Avian Diseases
https://www.readbyqxmd.com/read/27899636/the-monarch-initiative-an-integrative-data-and-analytic-platform-connecting-phenotypes-to-genotypes-across-species
#7
Christopher J Mungall, Julie A McMurry, Sebastian Köhler, James P Balhoff, Charles Borromeo, Matthew Brush, Seth Carbon, Tom Conlin, Nathan Dunn, Mark Engelstad, Erin Foster, J P Gourdine, Julius O B Jacobsen, Dan Keith, Bryan Laraway, Suzanna E Lewis, Jeremy NguyenXuan, Kent Shefchek, Nicole Vasilevsky, Zhou Yuan, Nicole Washington, Harry Hochheiser, Tudor Groza, Damian Smedley, Peter N Robinson, Melissa A Haendel
The correlation of phenotypic outcomes with genetic variation and environmental factors is a core pursuit in biology and biomedicine. Numerous challenges impede our progress: patient phenotypes may not match known diseases, candidate variants may be in genes that have not been characterized, model organisms may not recapitulate human or veterinary diseases, filling evolutionary gaps is difficult, and many resources must be queried to find potentially significant genotype-phenotype associations. Non-human organisms have proven instrumental in revealing biological mechanisms...
November 29, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27895289/management-prevention-and-treatment-of-canine-leishmaniosis-in-north-eastern-spain-an-online-questionnaire-based-survey-in-the-province-of-girona-with-special-emphasis-on-new-preventive-methods-canileish-vaccine-and-domperidone
#8
S Lladró, A Picado, C Ballart, M Portús, M Gállego
Knowledge of how canine leishmaniosis (CanL) is being managed clinically and its epidemiology is very important, since dogs are the main reservoir of human leishmaniosis. This study reports the results obtained through a questionnaire-based survey of veterinary practitioners in Girona province, a recognised, but non-documented endemic area in north-eastern Spain. The primary objective was to obtain data on the clinical management of CanL, focusing particularly on new preventive methods and therapeutic tools...
November 28, 2016: Veterinary Record
https://www.readbyqxmd.com/read/27895011/evaluation-of-fluoroquinolone-activity-against-emergence-of-resistant-salmonella-enterica-serovar-typhimurium-using-in-vitro-dynamic-models
#9
Seung-Jin Lee, Elias Gebru Awji, Na-Hye Park, Seung-Chun Park
The objectives of this study were to determine pharmacokinetic/pharmacodynamic (PK/PD) indices of fluoroquinolones that minimize the emergence of resistant Salmonella enterica serovar Typhimurium (S. Typhimurium) using in vitro dynamic models, and to establish mechanisms of resistance. Three fluoroquinolones, difloxacin (DIF), enrofloxacin (ENR) and marbofloxacin (MAR), at five dose levels and 3 days of treatment were simulated. Bacterial killing-regrowth kinetics and emergence of resistant bacteria after antibacterial drug- exposure were quantified...
November 28, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27893949/phenotypic-and-genotypic-resistance-of-salmonella-isolates-from-healthy-and-diseased-pigs-in-china-during-2008-2015
#10
Yueguang Jiu, Shun Zhu, Sher Bahadar Khan, Mengzhen Sun, Geng Zou, Xianrong Meng, Bin Wu, Rui Zhou, Shaowen Li
The antimicrobial resistance of Salmonella strains is rapidly increasing worldwide, which poses significant threats to animal and public health. In this study, a total of 249 porcine Salmonella isolates collected in China during 2008-2015 were examined, including 155 clinical isolates from diseased pigs and 94 nonclinical isolates from healthy pigs. Based on the minimum inhibitory concentration of seven antimicrobial agents, 96.4% of the isolates were resistant to at least one of the tested antibiotics and 81...
November 28, 2016: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/27891499/a-presumptive-case-of-human-rabies-a-rare-survived-case-in-rural-ghana
#11
Paschal Awingura Apanga, John Koku Awoonor-Williams, Michael Acheampong, Matthew Ayamba Adam
Rabies remains endemic in Ghana and continues to pose a major public health threat to humans and animals with a nearly 100% case fatality rate in humans. We report of a presumptive case of human rabies whose survival represents a rare occurrence in rural Ghana and worldwide. Lessons from this case study provide a critically needed focus in helping improve rabies surveillance and case management in Ghana. We report of the survival of a 36-year-old man who developed clinical rabies after he was bitten by his dog, while restraining the dog with a chain...
2016: Frontiers in Public Health
https://www.readbyqxmd.com/read/27890443/oxa-23-and-isaba1-oxa-66-class-d-%C3%AE-lactamases-in-acinetobacter-baumannii-isolates-from-companion-animals
#12
Christa Ewers, Peter Klotz, Ursula Leidner, Ivonne Stamm, Ellen Prenger-Berninghoff, Stephan Göttig, Torsten Semmler, Sandra Scheufen
Acinetobacter baumannii is recognised as a major pathogen of nosocomial infections that frequently show resistance to last-resort antimicrobials. To investigate whether A. baumannii from companion animals harbour carbapenem resistance mechanisms, 223 clinical isolates obtained from veterinary clinics between 2000 and 2013 in Germany were screened for carbapenem-non-susceptibility employing meropenem-containing Mueller-Hinton agar plates. Minimum inhibitory concentration (MIC) data were obtained using the VITEK(®)2 system...
November 16, 2016: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/27888321/genetic-characterization-of-canine-parvovirus-type-2-subtypes-in-maputo-mozambique
#13
J Figueiredo, C Miranda, R Souto, E Silva, J Fafetine, G Thompson
Canine parvovirus type 2 (CPV-2) comprises three antigenic subtypes (2a, 2b and 2c) that have been reported in many countries. These subtypes cause serious disease in dogs with characteristic gastroenteritis signs. Little information has been documented in Africa about the genetic characterization of CPV-2. The aim of this study was to detect and to characterize the CPV-2 subtypes circulating in dogs admitted to Veterinary Clinics from two cities of Mozambique, Maputo and Matola, in 2010. A total of 40 field fecal samples were collected and tested for CPV-2 by polymerase chain reaction assay...
November 25, 2016: Archives of Microbiology
https://www.readbyqxmd.com/read/27882744/transpalpebral-exenteration-in-cattle-a-retrospective-study-of-115-cases
#14
Munashe Chigerwe, John A Angelos, Lisa Gamsjäeger, Meera C Heller
OBJECTIVE: To describe the indications for exenteration and complications associated with the procedure. ANIMALS STUDIED: 115 cattle. PROCEDURES: Medical records of cattle presented for unilateral exenteration evaluated at the University of California, Davis Veterinary Medical Teaching Hospital from January 1985 through December 2015 were reviewed. RESULTS: Median (range) age at presentation for all cattle was 6 (0.2-30) years...
November 24, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27876993/a-unique-case-of-babesia-gibsoni-infected-dog-with-paraplegia
#15
Suresh Gonde, S Chhabra, S K Uppal, L D Singla, S S Randhawa
A 4 year old male Rottweiler was presented to Teaching Veterinary Clinics of GADVASU with a primary complaint of paraplegia, fever and inappetence. The dog was found to be dull with elevated rectal temperature (105 °F), heart rate (158 per minute) and respiration rate (57 per minute). Blood smear examination and PCR assay revealed that dog was positive for Babesia gibsoni. Elevated bilirubin, alanine aminotransferase, alkaline phosphatase, creatinine, total leucocyte count, neutrophils and hypoglycaemia were haemato-biochemical alterations...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27876992/traditional-versus-molecular-based-detection-of-a-rare-occurrence-of-babesiosis-in-gir-calf-and-its-therapeutic-management
#16
Biswa Ranjan Maharana, Binod Kumar, Nitinkumar Devrajbhai Hirani
A 30-day old Gir calf was brought to Veterinary Polyclinic with symptoms of high fever, dullness, dyspnea, pale mucus membrane and haemoglobinuria. Blood sample was collected and microscopic examination of thin blood smear confirmed the case of acute babesiosis. It was further confirmed by polymerase chain reaction that amplified an approximately 410 bp portion of the ssu-rDNA of Babesia spp. The calf was managed with diminazene aceturate @5 mg/kg (Berenil) intramuscularly followed by supportive therapy including intravenous infusions...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27876944/seasonal-incidence-of-parasitic-diseases-in-bovines-of-south-western-gujarat-junagadh-india
#17
Binod Kumar, B R Maharana, Amit Prasad, Joice P Joseph, Bhavika Patel, J S Patel
The current study was conducted to investigate the incidence of parasitic diseases in bovines which were sick and brought at veterinary hospital for treatment. A total of 366 samples were investigated from cattle (n = 175) and buffaloes (n = 191) presented at Teaching Veterinary Clinical Complex (TVCC), Veterinary College, Junagadh, Gujarat during January to December 2014. Examination of Giemsa-stained peripheral blood smears exhibited that 58.6 % of cattle and 41.2 % of buffaloes were infected with haemoparasites comprising Babesia bigemina, Theileria annulata, and Anaplasma marginale @ of 54...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27876941/toxocara-vitulorum-in-a-suckling-calf-a-case-study
#18
Rayies Ahmed, Z A Wani, I M Allaie, M S Bushra, H A Hussain
The present clinical case reports toxocariosis in a suckling calf and its management. One and a half month old crossbred Jersey calf was presented at a Veterinary Clinics, District Pulwama, Kashmir with a history of intermittent diarrhea, poor growth, weakness, moderate dehydration and anorexia. On inspection, the calf showed normal physiological parameters viz; body temperature, pulse rate and respiration rate. On faecal examination, eggs of Toxocara vitulorum were found. The animal was treated with 30 ml suspension of 1...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27876613/multiplex-amplification-refractory-mutation-system-pcr-arms-pcr-provides-sequencing-independent-typing-of-canine-parvovirus
#19
Vishal Chander, Soumendu Chakravarti, Vikas Gupta, Sukdeb Nandi, Mithilesh Singh, Surendra Kumar Badasara, Chhavi Sharma, Mitesh Mittal, S Dandapat, V K Gupta
Canine parvovirus-2 antigenic variants (CPV-2a, CPV-2b and CPV-2c) ubiquitously distributed worldwide in canine population causes severe fatal gastroenteritis. Antigenic typing of CPV-2 remains a prime focus of research groups worldwide in understanding the disease epidemiology and virus evolution. The present study was thus envisioned to provide a simple sequencing independent, rapid, robust, specific, user-friendly technique for detecting and typing of presently circulating CPV-2 antigenic variants. ARMS-PCR strategy was employed using specific primers for CPV-2a, CPV-2b and CPV-2c to differentiate these antigenic types...
October 29, 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27876455/multiple-morbidities-in-companion-dogs-a-novel-model-for-investigating-age-related-disease
#20
Kelly Jin, Jessica M Hoffman, Kate E Creevy, Dan G O'Neill, Daniel E L Promislow
The proportion of men and women surviving over 65 years has been steadily increasing over the last century. In their later years, many of these individuals are afflicted with multiple chronic conditions, placing increasing pressure on healthcare systems. The accumulation of multiple health problems with advanced age is well documented, yet the causes are poorly understood. Animal models have long been employed in attempts to elucidate these complex mechanisms with limited success. Recently, the domestic dog has been proposed as a promising model of human aging for several reasons...
2016: Pathobiology of Aging & Age related Diseases
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