keyword
MENU ▼
Read by QxMD icon Read
search

Dermatophytes

keyword
https://www.readbyqxmd.com/read/27907185/antioxidant-antimicrobial-and-cytotoxic-properties-as-well-as-the-phenolic-content-of-the-extract-from-hancornia-speciosa-gomes
#1
Uilson P Santos, Jaqueline F Campos, Heron Fernandes V Torquato, Edgar Julian Paredes-Gamero, Carlos Alexandre Carollo, Leticia M Estevinho, Kely de Picoli Souza, Edson Lucas Dos Santos
Hancornia speciosa Gomes (Apocynaceae) is a fruit tree, popularly known as mangabeira, and it is widely distributed throughout Brazil. Several parts of the plant are used in folk medicine, and the leaf and bark extracts have anti-inflammatory, antihypertensive, antidiabetic, and antimicrobial properties. In this study, we investigated the chemical composition of the ethanolic extract of Hancornia speciosa leaves (EEHS) and its antioxidant, antimicrobial, and cytotoxic activities as well as the mechanisms involved in cell death...
2016: PloS One
https://www.readbyqxmd.com/read/27904057/potential-of-ravuconazole-and-its-prodrugs-as-the-new-oraltherapeutics-for-onychomycosis
#2
Hideyo Yamaguchi
Onychomycosis is a fungal infection of the nail apparatus caused by dermatophytes, Candida and non-dermatophytic molds. It is highly prevalent in the general population worldwide and also responsible for significant morbidity and complications and does not usually cure itself. Thus, the condition needs to be treated in view of physical and psychological problems produced. Currently, oral medications using terbinafine are the most effective therapy, but it has relatively limited therapeutic success, particularly for long-term management...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27904054/epidemiology-of-dermatophytoses-in-crete-greece
#3
Sofia Maraki, Viktoria Eirini Mavromanolaki
Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. The aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in Crete, Greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. We compared our findings with those previously reported from the same area and from other parts of the world...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27890967/airborne-pollen-and-fungal-spores-in-garki-abuja-north-central-nigeria
#4
Dimphna Nneka Ezike, Catherine V Nnamani, Oluwatoyin T Ogundipe, Olushola H Adekanmbi
The ambient atmosphere is dominated with pollen and spores, which trigger allergic reactions and diseases and impact negatively on human health. A survey of pollen and fungal spores constituents of the atmosphere of Garki, Abuja (North-Central Nigeria) was carried out for 1 year (June 1, 2011-May 31, 2012). The aim of the study was to determine the prevalence and abundance of pollen and fungal spores in the atmosphere and their relationship with meteorological parameters. Airborne samples were trapped using modified Tauber-like pollen trap, and the recipient solutions were subjected to acetolysis...
2016: Aerobiologia
https://www.readbyqxmd.com/read/27878642/are-th17-cells-playing-a-role-in-immunity-to-dermatophytosis
#5
Marie-Pierre Heinen, Ludivine Cambier, Laurence Fievez, Bernard Mignon
Despite their superficial localization in the skin, pathogenic dermatophytes can induce a complex but still misunderstood immune response in their hosts. The cell-mediated immunity (CMI) is correlated with both clinical recovery and protection against reinfection, and CD4+ T lymphocytes have been recognized as a crucial component of the immune defense against dermatophytes. Before the discovery of the Th17 pathway, CMI was considered to be only dependent of Th1 cells, and thus most studies on the immunology of dermatophytosis have focused on the Th1 pathway...
November 23, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27876749/anti-fungal-activity-of-ctn-15-34-the-c-terminal-peptide-fragment-of-crotalicidin-a-rattlesnake-venom-gland-cathelicidin
#6
Carolina Sidrim P Cavalcante, Cláudio B Falcão, Raquel Os Fontenelle, David Andreu, Gandhi Rádis-Baptista
Crotalicidin (Ctn), a 34-residue cathelicidin from a South American rattlesnake, and its fragment (Ctn[15-34]) have shown anti-infective and cytotoxic activities against Gram-negative bacteria and certain tumor lines, respectively. The extent of such effects has been related to physicochemical characteristics such as helicity and hydrophobicity. We now report the anti-fungal activity of Ctn and its fragments (Ctn[1-14]) and (Ctn[15-34]). MIC determination and luminescent cell viability assays were used to evaluate the anti-infective activity of Ctn and its fragments (Ctn[1-14]) and (Ctn[15-34]) as anti-fungal agents against opportunistic yeast and dermatophytes...
November 23, 2016: Journal of Antibiotics
https://www.readbyqxmd.com/read/27876085/onychomycosis-in-diabetic-patients-in-fako-division-of-cameroon-prevalence-causative-agents-associated-factors-and-antifungal-sensitivity-patterns
#7
Marvlyn Eba, Anna Longdoh Njunda, Rene Njikam Mouliom, Emmanuel Tebit Kwenti, Anold Nsoh Fuh, Gordon Takop Nchanji, Julius Atashili
BACKGROUND: Onychomycosis is an infection of the nail unit by a fungus. This is a very common infection amongst diabetics. Its occurrence among diabetics in Fako division is unknown. In this study we provide information on the characteristics of onychomycosis in diabetics in Fako division, Cameroon. METHODS: A cross-sectional descriptive and analytical hospital-based study was conducted in two diabetic clinics in the Buea and Limbe regional hospitals. We recruited 152 consenting diabetics into the study...
November 22, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27868472/topical-and-systemic-antifungals-in-dermatology-practice
#8
Murat Durdu, Macit Ilkit, Yalda Tamadon, Ali Tolooe, Haleh Rafati, Seyedmojtaba Seyedmousavi
Dermatophytosis is generally defined as an infection of the hair, nails, or glabrous skin. These infections are caused by the keratinophilic fungi Trichophyton spp., Microsporum spp., and Epidermophyton, which have been recovered from both symptomatic and asymptomatic individuals. Although dermatophytosis is generally not a life-threatening condition, these types of infections are among the most common infections worldwide, and their incidence has continued to increase consistently in recent years. Area covered: This article provides an overview of the general characteristics of dermatophytes, including their taxonomy and epidemiology, as well as the different clinical forms and laboratory diagnostics of dermatophytosis...
November 19, 2016: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/27866353/nimesulide-inhibits-pathogenic-fungi-pge2-dependent-mechanisms
#9
Rafaelle Fonseca de Matos, Lúcia Carla Vasconcelos Mendonça, Kaira Geiliane da Silva Souza, Adriana Aparecida Durães Fonseca, Elaine Mirla Souza Costa, Marcus Vinicius Dias de Lima, José Maria Dos Santos Vieira, Mioni Thielli Figueiredo Magalhães de Brito, Marta Chagas Monteiro
Certain non-steroidal anti-inflammatory drugs can inhibit fungal growth, fungal prostaglandin E2 production, and enzyme activation. This study aims to investigate the antifungal effect of nimesulide against pathogenic filamentous fungi and yeast. The experiments detailed below were also designed to investigate whether the action is dependent on E2 fungal prostaglandins. Our data showed that nimesulide exhibited potent antifungal activity, mainly against Trichophyton mentagrophytes (ATCC 9533) and Cryptococcus neoformans with MIC values of 2 and 62 μg/mL, respectively...
November 19, 2016: Folia Microbiologica
https://www.readbyqxmd.com/read/27859475/correlation-between-histopathologic-features-and-likelihood-of-identifying-superficial-dermatophytosis-with-periodic-acid-schiff-diastase-staining-a-cohort-study
#10
Michael Z Wang, Ruifeng Guo, Julia S Lehman
BACKGROUND: Periodic Acid Schiff-Diastase (PAS-D) staining is used routinely in dermatopathology. Conventionally, parakeratosis or intracorneal neutrophils justify use of PAS-D stain to identify dermatophytosis. We aimed to investigate the histopathological features of superficial dermatophytosis. METHODS: Skin biopsies with PAS-D stain were retrospectively reviewed by a blinded dermatopathologist. Histopathologic findings in cases with dermatophytosis were compared to those without...
November 17, 2016: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/27853914/non-dermatophyte-dermatoses-mimicking-dermatophytoses-in-animals
#11
Didier Pin
Dermatophytoses in animals are fungal diseases of the skin caused by dermatophyte fungi of the genus Microsporum or Trichophyton. Because the infection is generally follicular, the most common clinical sign is one or many circular areas of alopecia with variable erythema, scaling and crusting, and the primary differential diagnoses are follicular infections, such as bacterial folliculitis and demodicosis. Although dermatophyte folliculitis or ringworm is the most commonly observed lesion of dermatophytoses in animals, other presentations may be observed according to the host species and the dermatophyte involved: dermatophyte folliculitis or ringworm, scaling and crusting in dermatophytosis due to Microsporum persicolor, nodule in case of kerion or mycetoma, matted hairs, seborrheic dermatosis or miliary dermatitis in cats, generalized exfoliative dermatoses in dogs, cats and horses, superficial non-follicular pustules, papules and macules in the Devon Rex cat, pruritic dermatophytoses in dogs, cats and horses, and onychomycosis in dogs, cats and horses...
November 16, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27822542/rna-sequencing-based-genome-reannotation-of-the-dermatophyte-arthroderma-benhamiae-and-characterization-of-its-secretome-and-whole-gene-expression-profile-during-infection
#12
Van Du T Tran, Niccolò De Coi, Marc Feuermann, Emanuel Schmid-Siegert, Elena-Tatiana Băguţ, Bernard Mignon, Patrice Waridel, Corinne Peter, Sylvain Pradervand, Marco Pagni, Michel Monod
Dermatophytes are the most common agents of superficial mycoses in humans and animals. The aim of the present investigation was to systematically identify the extracellular, possibly secreted, proteins that are putative virulence factors and antigenic molecules of dermatophytes. A complete gene expression profile of Arthroderma benhamiae was obtained during infection of its natural host (guinea pig) using RNA sequencing (RNA-seq) technology. This profile was completed with those of the fungus cultivated in vitro in two media containing either keratin or soy meal protein as the sole source of nitrogen and in Sabouraud medium...
July 2016: MSystems
https://www.readbyqxmd.com/read/27815659/in-vitro-antifungal-susceptibility-of-neoscytalidium-dimidiatum-clinical-isolates-from-malaysia
#13
Jasper Elvin James, Jacinta Santhanam, Mei Chen Lee, Choon Xian Wong, Parameswari Sabaratnam, Hamidah Yusoff, Mohd Nizam Tzar, Mohd Fuat Abdul Razak
Neoscytalidium dimidiatum is an opportunistic fungus causing cutaneous infections mostly, which are difficult to treat due to antifungal resistance. In Malaysia, N. dimidiatum is associated with skin and nail infections, especially in the elderly. These infections may be mistaken for dermatophyte infections due to similar clinical appearance. In this study, Neoscytalidium isolates from cutaneous specimens, identified using morphological and molecular methods (28 Neoscytalidium dimidiatum and 1 Neoscytalidium sp...
November 4, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27815078/ziziphora-tenuior-l-essential-oil-from-dana-biosphere-reserve-southern-jordan-chemical-characterization-and-assessment-of-biological-activities
#14
M S Abu-Darwish, C Cabral, M J Gonçalves, C Cavaleiro, M T Cruz, M Paoli, F Tomi, T Efferth, L Salgueiro
ETHNOPHARMACOLOGIC RELEVANCE: Ziziphora tenuior L. (Lamiaceae) is a medicinal plant in Jordan, which is included in various antimicrobial, antiseptic, expectorant and wound healing preparations. It is used for the treatment of cough, stomach ache, dysentery, fever, uterus infection, gut inflammation and painful menstruation. AIM OF THE STUDY: The aim of this study was to assess, for the first time, the chemical composition of the essential oil of Z. tenuior originated from southern Jordan and its antifungal effects against several yeasts...
November 1, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27813064/factors-influencing-cure-rates-of-non-dermatophyte-mold-and-candida-onychomycosis-analysis-of-outcomes-in-81-patients-who-completed-treatment
#15
Ranthilaka R Ranawaka, S H Padmal de Silva
OBJECTIVES: Onychomycosis shows a poor response to current topical, oral, or device-related antifungal therapies. The aim of this study was to identify factors influencing the cure rates of non-dermatophyte mold and Candida onychomycosis. METHODS: Eighty-one patients who completed treatments were divided into "cured" and "non-cured" groups. The statistical significance of differences between the two groups was studied. RESULTS: Male gender (P < 0...
November 4, 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/27811180/a-new-marker-sequence-for-systematics-of-medically-important-fungi-based-on-amino-acid-sequence-of-the-largest-subunit-of-rna-polymerase-i
#16
Chiaki Yamanishi, Mohamed Mahdi Alshahni, Ayako Sano, Ikuo Nakamura, Koichi Makimura
Molecular evolution has dominated taxonomic studies for decades, replacing traditional methods for identification and classification. However, there is a need for better markers to resolve the problems that have limited their usefulness. In this report, we introduce the protein tag (Ptag) sequence, a highly polymorphic amino acid sequence within the C-terminal region of the largest subunit of RNA polymerase I, as a new systematic tag sequence for delineating the evolutionary history of medically important fungi...
November 2, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27807151/identification-of-molds-by-maldi-tof-mass-spectrometry
#17
Maurizio Sanguinetti, Brunella Posteraro
Despite to lesser extent than the diagnostic bacteriology, MALDI-TOF MS has recently revolutionized the diagnostic mycology workflow. With regards to filamentous fungi (or molds), the precise recognition of pathogenic species is important for rapid diagnosis and appropriate treatment, especially in invasive diseases. This review summarizes the current experience with MALDI-TOF MS-based identification of common and uncommon mold species, belonging to Aspergillus, Fusarium, Mucorales, dimorphic fungi, and dermatophytes...
November 2, 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27800138/growing-incidence-of-non-dermatophyte-onychomycosis-in-tehran-iran
#18
Marjan Motamedi, Zeinab Ghasemi, Mohammad Reza Shidfar, Leila Hosseinpour, Hossein Khodadadi, Kamiar Zomorodian, Hossein Mirhendi
BACKGROUND: Non-dermatophyte onychomycosis (NDO) is caused by a wide range of mold fungi other than dermatophytes, and has been reported at various rates in different countries worldwide. Studies on the incidence of NDO in the community are essential for understanding its epidemiology and control, as well as for the appropriate treatment of these infections. OBJECTIVES: In this study, the incidence of NDO in Tehran, Iran, was compared to the incidence of onychomycoses due to dermatophytes and yeasts...
August 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/27795791/-late-onset-dermatophytic-disease
#19
Christelle Natacha Ebongo Aboutou, Fouzia Hali, Soumya Chihab
Dermatophytic disease, described for the first time in 1959 by Hadida and Schousboe, is a chronic dermatophyte infection of the skin and viscera. It is a rare disease occurring mainly in Maghreb. Immunological studies have highlighted a deficit of cellular immunity with autosomal recessive transmission responsible for tolerance to dermatophyte. The first signs of this disease usually occur during childhood. Our patient suffered from pachyonychia affecting all his nails and erythematous, circinate, pruritic, scaly lesions occurring in all his seed coat from the age of 50 years...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27790797/causative-agents-of-onychomycosis-a-7-year-study
#20
Mostafa Chadeganipour, Rasoul Mohammadi
BACKGROUND: Onychomycosis is principally caused by dermatophyte species, but nondermatophyte molds and yeasts have also been involved, causing different clinical manifestations. The aim of this investigation is to determine the clinicomycological and epidemiological profile of the etiologic agents of onychomycosis. METHODS: The study population included 9,785 suspected cases of onychomycosis referred to the Medical Mycology Reference Laboratory in Isfahan, Iran, during 2007-2014...
November 2016: Journal of Clinical Laboratory Analysis
keyword
keyword
47262
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"