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Fluoride IQ

Xingchen Yu, Jingwen Chen, Yonggang Li, Hongliang Liu, Changchun Hou, Qiang Zeng, Yushan Cui, Liang Zhao, Pei Li, Ziquan Zhou, Shuo Pang, Sha Tang, Kunming Tian, Qian Zhao, Lixin Dong, Chunyan Xu, Xiao Zhang, Shun Zhang, Li Liu, Aiguo Wang
BACKGROUND: Excessive fluoride exposure is associated with adverse health outcomes, but little is known of the effects of moderately chronic fluoride exposure on children's health. OBJECTIVES: We conducted a cross-sectional study to explore the health impact of moderately excessive fluoride in drinking water. METHODS: We recruited 2886 resident children, aged 7 to 13 years, randomly from endemic and non-endemic fluorosis areas in Tianjin, China...
June 2, 2018: Environment International
Tetsuo Nakamoto, H Ralph Rawls
Fluoride, one of the most celebrated ingredients for the prevention of dental caries in the 20th century, has also been controversial for its use in dentifrices and other applications. In the current review, we have concentrated primarily on early-life exposure to fluoride and how it may affect the various organs. The most recent controversial aspects of fluoride are related to toxicity of the developing brain and how it may possibly result in the decrease of intelligence quotient (IQ), autism, and calcification of the pineal gland...
May 15, 2018: Journal of Clinical Pediatric Dentistry
Lino M Sawicki, Susanne Lütje, Xenofon Baraliakos, Jürgen Braun, Julian Kirchner, Johannes Boos, Philipp Heusch, Verena Ruhlmann, Ken Herrmann, Lale Umutlu, Harald H Quick, Gerald Antoch, Christian Buchbender
INTRODUCTION: Focal (18) F-Fluoride uptake on blood-pool phase PET represents regional hyperaemia, while it indicates osteoblastic activity on mineralization phase PET. This study investigates the link between regional hyperaemia and osteoblastic activity in inflammatory and chronic lesions of ankylosing spondylitis (AS) of the sacroiliac joints (SIJ) using dual-phase (18) F-Fluoride PET/MRI. METHODS: Thirteen patients (six men, seven women, age: 37 ± 10 years) with active AS prospectively underwent dual-phase (18) F-Fluoride PET/MRI...
October 25, 2017: Journal of Medical Imaging and Radiation Oncology
Priyanka Razdan, Basavaraj Patthi, Jishnu Krishna Kumar, Nikhil Agnihotri, Prajakta Chaudhari, Monika Prasad
AIMS: The aim was to assess and correlate the influence of the concentration of fluoride in ingested water on the intelligence quotient (IQ) of 12-14-year-old youngsters in Mathura district. MATERIALS AND METHODS: A total of 219 children were selected, 75 from low F area, 75 medium F area, and 69 from high F area. The concentration of fluoride in the routinely ingested water was estimated using "Ion Selective Electrode method"; then, Raven's Test was utilized to estimate the IQ of the study participants...
September 2017: Journal of International Society of Preventive & Community Dentistry
Morteza Bashash, Deena Thomas, Howard Hu, E Angeles Martinez-Mier, Brisa N Sanchez, Niladri Basu, Karen E Peterson, Adrienne S Ettinger, Robert Wright, Zhenzhen Zhang, Yun Liu, Lourdes Schnaas, Adriana Mercado-García, Martha María Téllez-Rojo, Mauricio Hernández-Avila
BACKGROUND: Some evidence suggests that fluoride may be neurotoxic to children. Few of the epidemiologic studies have been longitudinal, had individual measures of fluoride exposure, addressed the impact of prenatal exposures or involved more than 100 participants. OBJECTIVE: Our aim was to estimate the association of prenatal exposure to fluoride with offspring neurocognitive development. METHODS: We studied participants from the Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT) project...
September 19, 2017: Environmental Health Perspectives
Amanda M Barberio, Carlos Quiñonez, F Shaun Hosein, Lindsay McLaren
OBJECTIVES: Recent studies have connected increased fluoride exposure with increased risk of neurodevelopmental-related outcomes, such as ADHD (attention deficit hyperactivity disorder) and lower IQ in children. Our primary objective was to examine the association between fluoride exposure and reported diagnosis of a learning disability among a population-based sample of Canadian children aged 3-12 years. METHODS: We analyzed data from Cycles 2 and 3 of the Canadian Health Measures Survey...
September 14, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
R Manju, Amitha M Hegde, Paul Parlees, Anisha Keshan
CONTEXT: Arsenic is a rare crystal element that naturally occurs in all environmental media. A combination of regional and site-specific biogeochemical and hydrological factors governs its dispersion in the environment. It has far reaching consequences on human health. Exposure to arsenic in drinking water has been associated with a decline in intellectual function in children. AIM: The aim of this study is to assess the relationship between exposure to arsenic by drinking water and children's intelligence in Karnataka state, India...
July 2017: Journal of Neurosciences in Rural Practice
A Aravind, R S Dhanya, Ajay Narayan, George Sam, V J Adarsh, M Kiran
AIM: The aim of the present study was to evaluate the relationship of drinking water fluoride levels with children's intelligence quotient (IQ). MATERIALS AND METHODS: Water was collected from initially identified endemic fluoride regions according to the geological research of Government of India. Fluoride concentration of the water was assessed by utilizing fluoride ion selective electrode, Orion 9609BN, and categorized on the basis of fluoride concentration into low, medium, and high-fluoride regions, i...
December 2016: Journal of International Society of Preventive & Community Dentistry
Kousik Das, Naba Kumar Mondal
There has been growing public concern about intellectual performance of children at high levels of fluoride exposure. A cross-sectional study was conducted in Simlapal Block of Bankura District, West Bengal, to find out the relationship between fluoride (F) exposure as exposure dose (ED) with dental fluorosis (DF), urinary fluoride concentration (UF), intelligence quotient (IQ) and body mass index (BMI). Fifty groundwater samples were collected from the target area. One hundred forty-nine children belonging to age group 6 to 18 years were considered for this study...
April 2016: Environmental Monitoring and Assessment
Bill Osmunson, Hardy Limeback, Chris Neurath
No abstract text is available yet for this article.
February 2016: American Journal of Public Health
Suleman Abbas Khan, Rahul Kumar Singh, Saumya Navit, Dheera Chadha, Nikita Johri, Pragati Navit, Anshul Sharma, Rachana Bahuguna
BACKGROUND: Fluoridation of drinking water, despite being regarded as one of the top ten public health achievements of the twentieth century, has remained a much debated concept. Various studies on animals and aborted human fetuses have confirmed that excessive fluoride intake during infancy and early childhood, causes a number of irreversible structural and functional changes in the CNS leading to memory, learning and intellectual deficits. AIM: To compare the IQ levels of school children of two different locations, having different fluoride levels in water, and to establish a relationship between fluoride levels, prevalence of fluorosis and its effect on IQ levels...
November 2015: Journal of Clinical and Diagnostic Research: JCDR
Shibu Thomas Sebastian, S Sunitha
INTRODUCTION: Besides dental and skeletal fluorosis, excessive fluoride intake can also affect the central nervous system without first causing the physical deformities associated with skeletal fluorosis. With the existence of widespread endemic fluorosis in India, the possible adverse effect of elevated fluoride in drinking water on the Intelligence Quotient (IQ) level of children is a potentially serious public health problem. AIMS AND OBJECTIVES: This study assessed the Intelligence Quotient (IQ) of school going children aged 10-12 years in villages of Mysore district with different fluoride levels...
October 2015: Journal of the Indian Society of Pedodontics and Preventive Dentistry
D Mondal, G Dutta, S Gupta
This research work is carried out to evaluate fluoride (F) hydrogeochemistry and its effect on the population of two endemic villages of Birbhum district, West Bengal. Fluoride concentration in drinking water varies from 0.33 to 18.08 mg/L. Hydrogeochemical evolution suggests that ion-exchange mechanism is the major controlling factor for releasing F in the groundwater. Most of the groundwater samples are undersaturated with respect to calcite and fluorite. Health survey shows that out of 235 people, 142 people suffer from dental fluorosis...
April 2016: Environmental Geochemistry and Health
Philippe Grandjean, Anna L Choi
No abstract text is available yet for this article.
April 2015: American Journal of Public Health
Shun Zhang, Xiaofei Zhang, Hongliang Liu, Weidong Qu, Zhizhong Guan, Qiang Zeng, Chunyang Jiang, Hui Gao, Cheng Zhang, Rongrong Lei, Tao Xia, Zhenglun Wang, Lu Yang, Yihu Chen, Xue Wu, Yushan Cui, Linyu Yu, Aiguo Wang
Cumulative fluoride exposure has adverse influences on children's intelligence quotient (IQ). In addition, catechol-O-methyltransferase (COMT) gene Val158Met polymorphism (rs4680) is associated with cognitive performance. This study aimed to evaluate the associations of COMT polymorphism and alterations of protein profiles with children's intelligence in endemic fluorosis area. We recruited 180 schoolchildren (10-12 years old) from high fluoride exposure (1.40 mg/l) and control areas (0.63 mg/l) in Tianjin City, China...
April 2015: Toxicological Sciences: An Official Journal of the Society of Toxicology
Jonathan M Broadbent, W Murray Thomson, Sandhya Ramrakha, Terrie E Moffitt, Jiaxu Zeng, Lyndie A Foster Page, Richie Poulton
Objectives. This study aimed to clarify the relationship between community water fluoridation (CWF) and IQ. Methods. We conducted a prospective study of a general population sample of those born in Dunedin, New Zealand, between April 1, 1972, and March 30, 1973 (95.4% retention of cohort after 38 years of prospective follow-up). Residence in a CWF area, use of fluoride dentifrice and intake of 0.5-milligram fluoride tablets were assessed in early life (prior to age 5 years); we assessed IQ repeatedly between ages 7 to 13 years and at age 38 years...
January 2015: American Journal of Public Health
B Seraj, M Shahrabi, M Shadfar, R Ahmadi, M Fallahzadeh, H Farrokh Eslamlu, M J Kharazifard
OBJECTIVE: Prolonged excessive intake of fluoride during child's growth and development stages has been associated with mental and physical problems. The aim of this study was to investigate the effect of excessive fluoride intake on the intelligence quotient (IQ) of children living in five rural areas in Makoo/Iran. MATERIALS AND METHODS: In this cross-sectional study, 293 children aged 6-11 years were selected from five villages in Makoo with normal fluoride (0...
2012: Journal of Dentistry of Tehran University of Medical Sciences
P Mahaboob Basha, N S Sujitha
In previous studies, we investigated a link between high fluoride exposure and functional IQ deficits in rats. This study is an extension conducted to explore the combined influence of physical exercise and temperature stress on the learning ability and memory in rats and to assess whether any positive modulation could be attenuated due to exercise regimen subjected to F-toxicated animals at different temperatures. Accumulation of ingested fluoride resulted significant inhibition in acetylcholinesterase activity (P < 0...
December 2012: Biological Trace Element Research
Anna L Choi, Guifan Sun, Ying Zhang, Philippe Grandjean
BACKGROUND: Although fluoride may cause neurotoxicity in animal models and acute fluoride poisoning causes neurotoxicity in adults, very little is known of its effects on children's neurodevelopment. OBJECTIVE: We performed a systematic review and meta-analysis of published studies to investigate the effects of increased fluoride exposure and delayed neurobehavioral development. METHODS: We searched the MEDLINE, EMBASE, Water Resources Abstracts, and TOXNET databases through 2011 for eligible studies...
October 2012: Environmental Health Perspectives
P K Shivaprakash, Kushagra Ohri, Hina Noorani
This study was conducted on 160 children, in the Bagalkot district of Karnataka state between August and October 2010, with the aim of finding out if there is a relation between dental fluorosis status and Intelligence Quotient (IQ). Children were categorized as, those suffering from dental fluorosis and those not suffering from dental fluorosis and for all children in both categories, Intelligence testing was done using the Raven's Coloured Progressive Matrices. The following observations were made from the data gathered: The mean IQ score of children without dental fluorosis was significantly higher than those children who had dental fluorosis...
April 2011: Journal of the Indian Society of Pedodontics and Preventive Dentistry
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