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Fluoride IQ

Kousik Das, Naba Kumar Mondal
There has been growing public concern about intellectual performance of children at high levels of fluoride exposure. A cross-sectional study was conducted in Simlapal Block of Bankura District, West Bengal, to find out the relationship between fluoride (F) exposure as exposure dose (ED) with dental fluorosis (DF), urinary fluoride concentration (UF), intelligence quotient (IQ) and body mass index (BMI). Fifty groundwater samples were collected from the target area. One hundred forty-nine children belonging to age group 6 to 18 years were considered for this study...
April 2016: Environmental Monitoring and Assessment
Bill Osmunson, Hardy Limeback, Chris Neurath
No abstract text is available yet for this article.
February 2016: American Journal of Public Health
Suleman Abbas Khan, Rahul Kumar Singh, Saumya Navit, Dheera Chadha, Nikita Johri, Pragati Navit, Anshul Sharma, Rachana Bahuguna
BACKGROUND: Fluoridation of drinking water, despite being regarded as one of the top ten public health achievements of the twentieth century, has remained a much debated concept. Various studies on animals and aborted human fetuses have confirmed that excessive fluoride intake during infancy and early childhood, causes a number of irreversible structural and functional changes in the CNS leading to memory, learning and intellectual deficits. AIM: To compare the IQ levels of school children of two different locations, having different fluoride levels in water, and to establish a relationship between fluoride levels, prevalence of fluorosis and its effect on IQ levels...
November 2015: Journal of Clinical and Diagnostic Research: JCDR
Shibu Thomas Sebastian, S Sunitha
INTRODUCTION: Besides dental and skeletal fluorosis, excessive fluoride intake can also affect the central nervous system without first causing the physical deformities associated with skeletal fluorosis. With the existence of widespread endemic fluorosis in India, the possible adverse effect of elevated fluoride in drinking water on the Intelligence Quotient (IQ) level of children is a potentially serious public health problem. AIMS AND OBJECTIVES: This study assessed the Intelligence Quotient (IQ) of school going children aged 10-12 years in villages of Mysore district with different fluoride levels...
October 2015: Journal of the Indian Society of Pedodontics and Preventive Dentistry
D Mondal, G Dutta, S Gupta
This research work is carried out to evaluate fluoride (F) hydrogeochemistry and its effect on the population of two endemic villages of Birbhum district, West Bengal. Fluoride concentration in drinking water varies from 0.33 to 18.08 mg/L. Hydrogeochemical evolution suggests that ion-exchange mechanism is the major controlling factor for releasing F in the groundwater. Most of the groundwater samples are undersaturated with respect to calcite and fluorite. Health survey shows that out of 235 people, 142 people suffer from dental fluorosis...
April 2016: Environmental Geochemistry and Health
Philippe Grandjean, Anna L Choi
No abstract text is available yet for this article.
April 2015: American Journal of Public Health
Shun Zhang, Xiaofei Zhang, Hongliang Liu, Weidong Qu, Zhizhong Guan, Qiang Zeng, Chunyang Jiang, Hui Gao, Cheng Zhang, Rongrong Lei, Tao Xia, Zhenglun Wang, Lu Yang, Yihu Chen, Xue Wu, Yushan Cui, Linyu Yu, Aiguo Wang
Cumulative fluoride exposure has adverse influences on children's intelligence quotient (IQ). In addition, catechol-O-methyltransferase (COMT) gene Val158Met polymorphism (rs4680) is associated with cognitive performance. This study aimed to evaluate the associations of COMT polymorphism and alterations of protein profiles with children's intelligence in endemic fluorosis area. We recruited 180 schoolchildren (10-12 years old) from high fluoride exposure (1.40 mg/l) and control areas (0.63 mg/l) in Tianjin City, China...
April 2015: Toxicological Sciences: An Official Journal of the Society of Toxicology
Jonathan M Broadbent, W Murray Thomson, Sandhya Ramrakha, Terrie E Moffitt, Jiaxu Zeng, Lyndie A Foster Page, Richie Poulton
Objectives. This study aimed to clarify the relationship between community water fluoridation (CWF) and IQ. Methods. We conducted a prospective study of a general population sample of those born in Dunedin, New Zealand, between April 1, 1972, and March 30, 1973 (95.4% retention of cohort after 38 years of prospective follow-up). Residence in a CWF area, use of fluoride dentifrice and intake of 0.5-milligram fluoride tablets were assessed in early life (prior to age 5 years); we assessed IQ repeatedly between ages 7 to 13 years and at age 38 years...
January 2015: American Journal of Public Health
B Seraj, M Shahrabi, M Shadfar, R Ahmadi, M Fallahzadeh, H Farrokh Eslamlu, M J Kharazifard
OBJECTIVE: Prolonged excessive intake of fluoride during child's growth and development stages has been associated with mental and physical problems. The aim of this study was to investigate the effect of excessive fluoride intake on the intelligence quotient (IQ) of children living in five rural areas in Makoo/Iran. MATERIALS AND METHODS: In this cross-sectional study, 293 children aged 6-11 years were selected from five villages in Makoo with normal fluoride (0...
2012: Journal of Dentistry of Tehran University of Medical Sciences
P Mahaboob Basha, N S Sujitha
In previous studies, we investigated a link between high fluoride exposure and functional IQ deficits in rats. This study is an extension conducted to explore the combined influence of physical exercise and temperature stress on the learning ability and memory in rats and to assess whether any positive modulation could be attenuated due to exercise regimen subjected to F-toxicated animals at different temperatures. Accumulation of ingested fluoride resulted significant inhibition in acetylcholinesterase activity (P < 0...
December 2012: Biological Trace Element Research
Anna L Choi, Guifan Sun, Ying Zhang, Philippe Grandjean
BACKGROUND: Although fluoride may cause neurotoxicity in animal models and acute fluoride poisoning causes neurotoxicity in adults, very little is known of its effects on children's neurodevelopment. OBJECTIVE: We performed a systematic review and meta-analysis of published studies to investigate the effects of increased fluoride exposure and delayed neurobehavioral development. METHODS: We searched the MEDLINE, EMBASE, Water Resources Abstracts, and TOXNET databases through 2011 for eligible studies...
October 2012: Environmental Health Perspectives
P K Shivaprakash, Kushagra Ohri, Hina Noorani
This study was conducted on 160 children, in the Bagalkot district of Karnataka state between August and October 2010, with the aim of finding out if there is a relation between dental fluorosis status and Intelligence Quotient (IQ). Children were categorized as, those suffering from dental fluorosis and those not suffering from dental fluorosis and for all children in both categories, Intelligence testing was done using the Raven's Coloured Progressive Matrices. The following observations were made from the data gathered: The mean IQ score of children without dental fluorosis was significantly higher than those children who had dental fluorosis...
April 2011: Journal of the Indian Society of Pedodontics and Preventive Dentistry
Yunpeng Ding, YanhuiGao, Huixin Sun, Hepeng Han, Wei Wang, Xiaohong Ji, Xuehui Liu, Dianjun Sun
There has been public concern about children's intellectual performance at high levels of fluoride exposure, but few studies provide data directly to the question of whether low fluoride exposure levels less than 3.0 mg/L in drinking water adversely associated with children's intelligence. In this survey, we investigated the effects of low fluoride exposure on children's intelligence and dental fluorosis. 331 children aged from 7 to 14 were randomly recruited from four sites in Hulunbuir City, China. Intelligence was assessed using Combined Raven Test-The Rural in China while dental fluorosis was diagnosed with Dean's index...
February 28, 2011: Journal of Hazardous Materials
Quanyong Xiang, Youxin Liang, Bingheng Chen
The paper entitled "Serum Fluoride Level and Children's Intelligence Quotient in Two Villages in China" by Xiang Quanyong et al, which was published online on 17 December 2010, has been withdrawn.
December 17, 2010: Environmental Health Perspectives
Yaming Ge, Ruiyan Niu, Jianhai Zhang, Jundong Wang
Epidemiological investigations reveal that high fluoride and low iodine have strong adverse effects on the intelligence quotient (IQ) of children. Studies also report that in some high fluoride areas, iodine deficiency also exists, especially in China. Here, with the proteomic techniques, we first report on the proteomic changes in brain proteins in offspring rats at postnatal day 20 exposed to high fluoride and/or low iodine. To investigate molecular mechanisms of central neural system injury induced by the above two elements, proteins were isolated and profiled by two-dimensional gel electrophoresis (2DE)...
January 2011: Archives of Toxicology
Qin-Qing Tang, Jun Du, Heng-Hui Ma, Shao-Jun Jiang, Xiao-Jun Zhou
This paper presents a systematic review of the literature concerning fluoride that was carried out to investigate whether fluoride exposure increases the risk of low intelligence quotient (IQ) in China over the past 20 years. MEDLINE, SCI, and CNKI search were organized for all documents published, in English and Chinese, between 1988 and 2008 using the following keywords: fluorosis, fluoride, intelligence, and IQ. Further search was undertaken in the website because this is a professional website concerning research on fluoride...
2008: Biological Trace Element Research
Diana Rocha-Amador, Maria Elena Navarro, Leticia Carrizales, Raúl Morales, Jaqueline Calderón
Recent evidence suggests that fluoride (F) and arsenic (As) may adversely affect intelligence quotient (IQ) scores. We explore the association between exposure to F and As in drinking water and intelligence in children. Three rural communities in Mexico with contrasting levels of F and As in drinking water were studied: Moctezuma (F 0.8+/-1.4 mg/L; As 5.8+/-1.3 microg/L); Salitral (F 5.3+/-0.9 mg/L; As 169+/-0.9 microg/L) and 5 de Febrero (F 9.4+/-0.9 mg/L; As 194+/-1.3 microg/L). The final study sample consisted of 132 children from 6 to 10 years old...
2007: Cadernos de Saúde Pública
San-Xiang Wang, Zheng-Hui Wang, Xiao-Tian Cheng, Jun Li, Zhi-Ping Sang, Xiang-Dong Zhang, Ling-Ling Han, Xiao-Yan Qiao, Zhao-Ming Wu, Zhi-Quan Wang
BACKGROUND: Recently, in a cross-sectional study of 201 children in Araihazar, Bangladesh, exposure to arsenic (As) in drinking water has been shown to lower the scores on tests that measure children's intellectual function before and after adjustment for sociodemographic features. OBJECTIVES: We investigated the effects of As and fluoride exposure on children's intelligence and growth. METHODS: We report the results of a study of 720 children between 8 and 12 years of age in rural villages in Shanyin county, Shanxi province, China...
April 2007: Environmental Health Perspectives
Daniel C N Chan, James S Wefel, W Frank Caughman
There is a wealth of information on preventive measures and procedures that can be used to care for paediatric and adolescent patients. However, few studies have been conducted in adult or geriatric populations, and an understanding of preventive and non-surgical treatment regimens for these patients is lacking. Traditionally, caries incidence is high among risk groups of low income, low dental IQ and certain ethnic subgroups, but we are now witnessing a high incidence of caries among middle-income and healthy adult patients with an imbalance of protective factors and cariogenic factors...
December 2004: Singapore Dental Journal
Shih-Chun Candice Lung, Pao-Kuei Hsiao, Kuang-Mao Chiang
Tea is a popular drink around the world. It is also one of the major sources of fluoride intake. The objectives of this study were to assess fluoride concentrations in popular non-, semi-, and full-fermented tea drinks sold on the Taiwan market. Concentration differences among three types of commercially available tea drinks (tea leaf, tea bag, and packaged tea beverage) were explored. Several influential factors in intake concentrations were evaluated. The acute threshold intake (ATI) and allowable daily intake (ADI) of those tea drinks were also estimated...
January 2003: Journal of Exposure Analysis and Environmental Epidemiology
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