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Ptca, stent

A Barone, M Otero-Losada, A M Grangeat, G Cao, F Azzato, A Rodríguez, J Milei
BACKGROUND: In-stent restenosis and poor re-endothelization usually follow percutaneous transluminal coronary angioplasty, even using drug-eluting stents, due to inflammation and oxidative stress. Medical ozone has antioxidant and anti-inflammatory properties and has not been evaluated in this context. OBJECTIVES: To evaluate whether ozonotherapy might reduce restenosis following bare metal stents implantation in relation to the redoxin system in pigs. METHODS: Twelve male Landrace pigs (51±9kg) underwent percutaneous transluminal circumflex coronary arteries bare metal stent implantation under heparine infusion and fluoroscopical guidance, using standard techniques...
November 15, 2016: International Journal of Cardiology
Jianfeng Lv, Xingmei Zhang, Shulin Ou, Shanshan Gu, Zhizhou Su, Shifei Tong, Bo Liu, Zhiyuan Song, Luxiang Chi
Cognitive behavioral therapy (CBT), established only a few decades ago, is widely used by clinical psychologists. This study aimed to investigate the effects of CBT on mental status and quality of life (QOL) after percutaneous coronary intervention (PCI) in young and middle-aged patients with coronary heart disease (CHD). Seventy-five anxiety/depression patients (mean age, 52.2 ± 6.2 years, including 8 individuals < 45 years old) with CHD treated with PCI were randomly divided into a CBT group (n = 38) and control group (n = 37)...
2016: International Heart Journal
Kai-Che Wei, Hon-Yi Lin, Shih-Kai Hung, Yu-Tung Huang, Moon-Sing Lee, Wen-Hua Wang, Chieh-Shan Wu, Yu-Chieh Su, Bing-Jie Shen, Shiang-Jiun Tsai, Wei-Ta Tsai, Liang-Cheng Chen, Chung-Yi Li, Wen-Yen Chiou
A number of cardiac fluoroscopic interventions have increased rapidly worldwide over the past decade. Percutaneous transluminal coronary angioplasty (PTCA) and stent implantation have become increasingly popular, and these advancements have allowed patients to receive repetitive treatments for restenosis. However, these advancements also significantly increase radiation exposure that may lead to higher cumulative doses of radiation. In the present study, a nationwide population-based case-controlled study was used to explore the risk of leukemia after cardiac angiographic fluoroscopic intervention...
March 2016: Medicine (Baltimore)
Chung-Wei Yang, Nian-Sheng Tzeng, Yun-Ju Yin, Chien-Hsun Li, Hung-An Chen, Shih-Hsiang Chiu, Shinn-Ying Ho, Hui-Ling Huang
BACKGROUND: Major adverse cardiovascular events (MACE) cause the leading cause of morbidity and mortality in patients with end-stage renal disease (ESRD) on maintenance Hemodialysis (HD) or peritoneal dialysis (PD). Many randomized-controlled trials (RCTs) have proved that angiotensin receptor blockers (ARBs) can reduce the risk of MACE in the people with normal or impaired kidney function without dialysis. This study seeks to clarify whether ARBs therapy could also attenuate this risk in patients with ESRD on maintenance dialysis...
2015: PloS One
Harald Rittger, Matthias Waliszewski, Johannes Brachmann, Wolfgang Hohenforst-Schmidt, Marc Ohlow, Andreas Brugger, Holger Thiele, Ralf Birkemeyer, Volkhard Kurowski, Christian Schlundt, Stefan Zimmermann, Sandra Lonke, Moritz von Cranach, Sinisa Markovic, Werner G Daniel, Stephan Achenbach, Jochen Wöhrle
OBJECTIVES: The intention this PEPCAD-DES (Treatment of Drug-eluting Stent [DES] In-Stent Restenosis With SeQuent Please Paclitaxel Eluting Percutaneous Transluminal Coronary Angioplasty [PTCA] Catheter) study update was to demonstrate the safety and efficacy of paclitaxel-coated balloon (PCB) angioplasty in patients with DES-ISR at 3 years. BACKGROUND: In the PEPCAD-DES trial late lumen loss and the need for repeat target lesion revascularization (TLR) was significantly reduced with PCB angioplasty compared with plain old balloon angioplasty (POBA) in patients with drug-eluting stent in-stent restenosis (DES-ISR) at 6 months...
November 2015: JACC. Cardiovascular Interventions
Alessandro Lupi, Andrea Rognoni, Alon Schaffer, Gioel G Secco, Angelo S Bongo
BACKGROUND: Mozec™ CTO is a novel semicompliant rapid-exchange PTCA balloon catheter with specific features dedicated to treat complex coronary lesions like chronic total occlusions (CTOs). However, no data have been reported about the performance of this device in an all-comers population with complex coronary lesions. METHODS: We evaluated the safety and success rate of Mozec™ CTO balloon in 41 consecutive patients with chronic stable angina and complex coronary lesions (15 severe calcified coronary stenoses, 15 bifurcation lesions with planned two-stent intervention, and 11 CTOs)...
2015: Clinical Medicine Insights. Cardiology
R P Szabó, I Varga, J Balla, L Zsom, B Nemes
INTRODUCTION: Cardiovascular disease is a major cause of morbidity and mortality in end-stage renal disease patients on dialysis and the most common cause of death in the immediate post-transplantation period. The aim of our study was to describe a novel approach of cardiovascular screening and management of dialysis patients evaluated for the transplant waiting list. METHODS: Twenty-eight patients with end-stage renal disease put on the waiting list between July 2013 and July 2014 were subjected to a prespecified cardiovascular screening protocol utilizing noninvasive and/or invasive tests...
September 2015: Transplantation Proceedings
David J Perkowski, Susan Wagner, Kathryn Muller, Joseph R Schneider, J A St Cyr
PURPOSE: Assessment of both short- and long-term outcomes in patients undergoing off-pump coronary artery bypass using a perioperative metabolic protocol. METHODS: A total of 975 of 995 adult patients underwent coronary artery bypass 'off-pump' from 1997 through 2006. Patients presenting in cardiogenic shock were excluded from this assessment. A perioperative metabolic protocol, which included the implementation of allopurinol, insulin supplementation, magnesium sulfate, supplemental corticosteroids, milrinone, norepinephrine (prn), aspirin, clopidogrel, statins and β-blockers, was used in these patients...
December 2015: Therapeutic Advances in Cardiovascular Disease
Shi-Min Yuan, Yun Li, Yan Hong Ben, Xiao Feng Cheng, Da Zhu Li, De Min Li, Hua Jing
OBJECTIVE: This study aims to present the graft pathology at the time of harvest and its impact on long-term survival. METHODS: The remnants of the bypass grafts from 66 consecutive patients with coronary artery disease receiving a coronary artery bypass grafting were investigated pathologically, and pertinent predictive risk factors and survival were analyzed. RESULTS: Medial degenerative changes with or without intimal proliferation were present in 36...
October 2014: Revista Brasileira de Cirurgia Cardiovascular
Derya Atik, Cem Atik, Hilal Karatepe
INTRODUCTION: Metabolic Syndrome (MetS) is basically a cluster of cardiovascular risks that involve changes in metabolic and hemodynamic indicators; various organizations have defined it with small differences. Metabolic syndrome is a lethal endocrinopathy starting with insulin resistance and inviting a chain of systemic disorders such as abdominal obesity, glucose intolerance or diabetes mellitus (DM), dyslipidemia, hypertension (HT) and coronary artery disease (CAD). MATERIAL AND METHODS: This prospective and descriptive study was conducted at the Cardiology Clinic of a Private Hospital in Osmaniye between January 2014 and May 2014...
December 2014: Acta Informatica Medica: AIM
Louisa O'Neill, Vinay Sowbhaga, Patrick Owens
This case outlines an unusual complication of coronary intervention, the likely mechanisms leading to this and possible retrieval options. It is the first case to the best of our knowledge reporting this complication. A 78-year-old Caucasian man underwent coronary stenting. During the procedure kinking and subsequent fracture of a non-compliant percutaneous transluminal coronary angioplasty (PTCA) balloon occurred. Injection of contrast down the guide to opacify the coronary arteries resulted in 'inflation' of the balloon with air, and embolisation of the inflated balloon into the proximal left anterior descending artery...
2015: BMJ Case Reports
Ozgür Ciftçi, Murat Günday, Tonguç Saba, Mehmet Ozülkü
A 74-year-old male patient was admitted to our emergency department with post-MI angina. On account of the anginal complaint that continued for three days, a coronary artery angiography was undertaken. A percutaneous transluminal coronary angioplasty was performed, followed by the implantation of a coronary stent, and coronary perfusion (TIMI-3) was achieved in the left anterior descending artery. Medical treatment (with acetylsalicylic acid, clopidogrel, metoprolol, atorvastatin and enoxaparine) and tirofiban infusion were duly administered in the coronary care unit...
August 2013: Research in Cardiovascular Medicine
Parag Chevli, Fnu Kelash, Pragnesh Gadhvi, Sreeram Grandhi, Amer Syed
Spontaneous coronary artery dissection (SCAD) is a rare cause of acute myocardial infarction that is more common in younger patients (under age 50) and in women. Although the etiology is not known, some predisposing conditions to SCAD are well known and include Marfan syndrome, pregnancy and peripartum state, drug abuse, and some anatomical abnormalities of the coronary arteries such as aneurysms and severe kinking. We describe a case of SCAD in a young woman who presented with sudden onset of chest pain and was admitted for the treatment of acute coronary syndrome...
2014: Journal of Community Hospital Internal Medicine Perspectives
Derya Atik, Cem Atik, Salih Paker, Mesut Işlek
RATIONALE, AIMS AND OBJECTIVES: This descriptive study was planned and conducted to determine whether or not gender is significant in patients administered coronary angiography with respect to smoking, peripheral arterial disease, diabetes mellitus and the procedure used. METHODS: Based on the hospital records that were scanned retrospectively, the study included patients aged 18 and over who were diagnosed with coronary arterial disease and were administered for the first time a coronary angiography procedure in the Cardiology Clinic of Osmaniye Private New Life Hospital between 1 September 2012 and 31 December 2013...
December 2014: Journal of Evaluation in Clinical Practice
Grant C Sorkin, Travis M Dumont, Jorge L Eller, Maxim Mokin, L Nelson Hopkins, Kenneth V Snyder, Adnan H Siddiqui, Elad I Levy
BACKGROUND: Treatment of instent restenosis after carotid artery stenting because of circumferential or calcified lesions can be difficult and refractory to conventional balloon angioplasty. We describe the off-label use of a cardiac scoring balloon that was used for lesions refractory to angioplasty with other balloons. CASE DESCRIPTIONS: Two patients with a history of carotid artery stenting 6 and 8 years ago, presented with symptomatic carotid instent restenosis caused by circumferential and calcified lesions, respectively...
May 2014: Journal of Vascular and Interventional Neurology
Thibaut Caruba, Sandrine Katsahian, Catherine Schramm, Anaïs Charles Nelson, Pierre Durieux, Dominique Bégué, Yves Juillière, Olivier Dubourg, Nicolas Danchin, Brigitte Sabatier
INTRODUCTION AND OBJECTIVES: Numerous studies have assessed cost-effectiveness of different treatment modalities for stable angina. Direct comparisons, however, are uncommon. We therefore set out to compare the efficacy and mean cost per patient after 1 and 3 years of follow-up, of the following treatments as assessed in randomized controlled trials (RCT): medical therapy (MT), percutaneous coronary intervention (PCI) without stent (PTCA), with bare-metal stent (BMS), with drug-eluting stent (DES), and elective coronary artery bypass graft (CABG)...
2014: PloS One
Thilo Storm, Katharina Wulf, Michael Teske, Marian Löbler, Günther Kundt, Frank Luderer, Klaus-Peter Schmitz, Katrin Sternberg, Marina Hovakimyan
The high degree of clinical routine in percutaneous transluminal coronary angioplasty (PTCA) with and without stenting has not changed the fact that a large number of coronary heart disease patients are still affected by post-operative complications such as restenosis and thrombosis. Because re-endothelialization is the crucial aspect of wound healing after cardiovascular implant surgery, there is a need for modern biomaterials to aid endothelial cells in their adhesion and functional recovery post-stenting...
August 2014: Journal of Materials Science. Materials in Medicine
Müntecep Aşker, Selvi Aşker, Ozgür Gürsu
Spontaneous coronary artery dissection (SCAD) is a deadly cause of myocardial infarction (MI) that mainly affects otherwise healthy, young females. Forty percent of patients die suddenly or within a few hours of symptom onset. We examine the case of a young female who presented with chest pain. She developed ST elevations in anterolateral leads mimicking ST elevation MI. Cardiac catheterization was done and showed a middle left anterior descending (LAD) dissection. The patient underwent primary percutaneous transluminal coronary angioplasty with coronary stent placed in the LAD...
2012: Case Reports in Cardiology
Paul Barragan, Vincent Garitey, Karim Mouneimne, Régis Rieu
AIMS: The aim of this study was to characterise the coronary stent longitudinal resistance of new coronary stents under worst case clinical crossing simulated configurations. METHODS AND RESULTS: Six coronary balloon-expandable stents were evaluated using two different tests. The first was a direct parallel plates longitudinal crush resistance test: it was conducted on stents deployed to 3 mm diameter, and three samples of each model were used. The second was performed by tracking over the wire and deploying the stents in two types of coronary model: good and malapposition models...
2014: EuroIntervention
Fabrizio D'Ascenzo, Francesco Colombo, Umberto Barbero, Claudio Moretti, Pierluigi Omedè, Matthew J Reed, Giuseppe Tarantini, Giacomo Frati, James J Di Nicolantonio, Giuseppe Biondi Zoccai, Fiorenzo Gaita
INTRODUCTION: Duration of dual antiplatelet therapy (DAPT) following acute coronary syndrome (ACS) hospitalization remains to be defined, both for patients treated medically and for those undergoing percutaneous transluminal coronary angioplasty (PTCA). METHODS: PubMed, Cochrane, and Google Scholar were systematically searched for studies including patients presenting with ACS, and treated either with DAPT longer than or shorter than 12 months. Multivariable-adjusted risk estimates for death and recurrent ACS with stopping DAPT after 12 months (odds ratios [OR] 95% confidence intervals [CI]) were pooled after logarithmic transformation according to random-effect models with inverse-variance weighting...
June 2014: Journal of Interventional Cardiology
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