Miguel A Ortega, Cielo García-Montero, Óscar Fraile-Martinez, Diego De Leon-Oliva, Diego Liviu Boaru, Coral Bravo, Juan A De Leon-Luis, Miguel A Saez, Angel Asúnsolo, Ignacio Romero-Gerechter, Alejandro Sanz-Giancola, Raul Diaz-Pedrero, Laura Lopez-Gonzalez, Luis G Guijarro, Silvestra Barrena-Blázquez, Julia Bujan, Natalio García-Honduvilla, Melchor Alvarez-Mon, Miguel Ángel Alvarez-Mon, Guillermo Lahera
Psychosis refers to a mental health condition characterized by a loss of touch with reality, comprising delusions, hallucinations, disorganized thought, disorganized behavior, catatonia, and negative symptoms. A first-episode psychosis (FEP) is a rare condition that can trigger adverse outcomes both for the mother and newborn. Previously, we demonstrated the existence of histopathological changes in the placenta of pregnant women who suffer an FEP in pregnancy. Altered levels of oxytocin (OXT) and vasopressin (AVP) have been detected in patients who manifested an FEP, whereas abnormal placental expression of these hormones and their receptors (OXTR and AVPR1A) has been proven in different obstetric complications...
June 16, 2023: International Journal of Molecular Sciences