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Tbi neuropsychology testing.

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https://www.readbyqxmd.com/read/29742960/amantadine-did-not-positively-impact-cognition-in-chronic-traumatic-brain-injury-a-multi-site-randomized-controlled-trial
#1
Flora Hammond, Mark Sherer, James F Malec, Ross D Zafonte, Sureyya Dikmen, Jennifer A Bogner, Kathleen Bell, Jason Barber, Nancy Temkin
Despite limited evidence to support the use of amantadine to enhance cognitive function after traumatic brain injury, the clinical use for this purpose is highly prevalent and is often based on inferred belief systems. The purpose of this study was to assess effect of amantadine on cognition among individuals with a history of traumatic brain injury and behavioral disturbance employing a parallel-group, randomized, double-blind, placebo-controlled trial of amantadine 100 mg twice daily vs placebo for 60 days...
May 10, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29734566/hyperbaric-oxygen-for-post-concussive-symptoms-in-united-states-military-service-members-a-randomized-clinical-trial
#2
Lindell K Weaver, Steffanie H Wilson, Anne S Lindblad, Susan Churchill, Kayla Deru, Robert C Price, Chris S Williams, William W Orrison, James M Walker, Anna Meehan, Susan Mirow
Background: In prior military randomized trials, participants with persistent symptoms after mild traumatic brain injury (TBI) reported improvement regardless of receiving hyperbaric oxygen (HBO₂) or sham intervention. This study's objectives were to identify outcomes for future efficacy trials and describe changes by intervention. Methods: This Phase II, randomized, double-blind, sham-controlled trial enrolled military personnel with mild TBI and persistent post-concussive symptoms...
March 2018: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29731669/transcranial-light-emitting-diode-therapy-for-neuropsychological-improvement-after-traumatic-brain-injury-a-new-perspective-for-diffuse-axonal-lesion-management
#3
REVIEW
João Gustavo Rocha Peixoto Dos Santos, Wellingson Silva Paiva, Manoel Jacobsen Teixeira
The cost of traumatic brain injury (TBI) for public health policies is undeniable today. Even patients who suffer from mild TBI may persist with cognitive symptoms weeks after the accident. Most of them show no lesion in computed tomography or conventional magnetic resonance imaging, but microstructural white matter abnormalities (diffuse axonal lesion) can be found in diffusion tensor imaging. Different brain networks work together to form an important part of the cognition process, and they can be affected by TBI...
2018: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/29676934/cognitive-profiles-of-older-adults-with-a-prior-traumatic-brain-injury-versus-healthy-controls-a-meta-analysis
#4
Kelly Y An, Mich C E Monette
OBJECTIVE: To determine cognitive outcomes in older adults (≥ 50 years old) having sustained a traumatic brain injury (TBI) using meta-analysis. METHODS: MedLine and PsycInfo databases were searched to identify studies comparing neuropsychological profiles in older adults with and without a history of TBI across various injury severities and times post-injury. Ten studies (n = 717) meeting inclusion criteria were identified. Tests were divided into functional modalities and average effect sizes were calculated across studies on a test-by-test basis...
April 20, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29648959/the-feasibility-of-telephone-administered-cognitive-testing-in-individuals-1-and-2-years-after-inpatient-rehabilitation-for-traumatic-brain-injury
#5
Kristen Dams-O'Connor, Karla Therese L Sy, Alexandra Landau, Yelena Bodien, Sureyya Dikmen, Elizabeth R Felix, Joseph T Giacino, Laura Gibbons, Flora M Hammond, Tessa Hart, Doug Johnson-Greene, Jeannie Lengenfelder, Anthony Lequerica, Jody Newman, Thomas Novack, Therese M O'Neil-Pirozzi, Gale Whiteneck
Traumatic brain injury (TBI) often results in cognitive impairment, and trajectories of cognitive functioning can vary tremendously over time across survivors. Traditional approaches to measuring cognitive performance require face-to-face administration of a battery of objective neuropsychological tests, which can be time- and labor-intensive. There are numerous clinical and research contexts in which in-person testing is undesirable or unfeasible, including clinical monitoring of older adults or individuals with disability for whom travel is challenging, and epidemiological studies of geographically dispersed participants...
March 13, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29611892/mlc901-neuroaid-ii-%C3%A2-for-cognition-after-traumatic-brain-injury-a-pilot-randomised-clinical-trial
#6
Alice Theadom, Suzanne Barker-Collo, Kelly M Jones, Priya Parmar, Rohit Bhattacharjee, Valery L Feigin
BACKGROUND: Treatments to facilitate recovery after traumatic brain injury (TBI) are urgently needed. To examine the safety and potential effects of herbal supplement MLC901 (NeuroAiD IITM ) on cognitive functioning following TBI, we conducted a nine-month pilot, randomised placebo-controlled clinical trial. METHODS: Adults aged 18-65 years, 1-12-months post-mild or moderate TBI, were randomised to receive MLC901 (0.8g capsules/day) or placebo for 6-months. The primary outcome was cognitive functioning assessed by the CNS-Vital Signs online neuropsychological test...
April 3, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29590406/medical-evaluation-board-involvement-non-credible-cognitive-testing-and-emotional-response-bias-in-concussed-service-members
#7
Scott R Mooney, Jane Stafford, Elizabeth Seats
Introduction: Military Service Members (SMs) with post-concussive symptoms are commonly referred for further evaluation and possible treatment to Department of Defense Traumatic Brain Injury Clinics where neuropsychological screening/evaluations are being conducted. Understudied to date, the base rates of noncredible task engagement/performance validity testing (PVT) during cognitive screening/evaluations in military settings appears to be high. The current study objectives are to: (1) examine the base rates of noncredible PVTs of SMs undergoing routine clinical or Medical Evaluation Board (MEB) related workups using multiple objective performance-based indicators; (2) determine whether involvement in MEB is associated with PVT or symptom exaggeration/symptom validity testing (SVT) results; (3) elucidate which psychiatric symptoms are associated with noncredible PVT performances; and (4) determine whether MEB participation moderates the relationship between psychological symptom exaggeration and whether or not SM goes on to demonstrate PVTs failures - or vice versa...
March 26, 2018: Military Medicine
https://www.readbyqxmd.com/read/29565696/an-investigation-of-white-matter-integrity-and-attention-deficits-following-traumatic-brain-injury
#8
Jacqueline Anne Owens, Gershon Spitz, Jennie Louise Ponsford, Alicia Rhian Dymowski, Catherine Willmott
OBJECTIVE: This study aimed to investigate the association between white matter tracts and multiple aspects of attention and working memory deficits in a relatively acute traumatic brain injury (TBI) sample. METHOD: Neuropsychological measures of attention and working memory were administered to 20 participants with complicated mild-to-very severe TBI and 20 control participants. Tract-based spatial statistics was used to assess fractional anisotropy (FA) and mean diffusivity (MD) of white matter tracts for 15 TBI participants and 20 controls...
March 22, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29444081/alpha-desynchronization-synchronization-during-working-memory-testing-is-compromised-in-acute-mild-traumatic-brain-injury-mtbi
#9
Xianghong Arakaki, Michael Shoga, Lianyang Li, George Zouridakis, Thao Tran, Alfred N Fonteh, Jessica Dawlaty, Robert Goldweber, Janice M Pogoda, Michael G Harrington
Diagnosing and monitoring recovery of patients with mild traumatic brain injury (mTBI) is challenging because of the lack of objective, quantitative measures. Diagnosis is based on description of injuries often not witnessed, subtle neurocognitive symptoms, and neuropsychological testing. Since working memory (WM) is at the center of cognitive functions impaired in mTBI, this study was designed to define objective quantitative electroencephalographic (qEEG) measures of WM processing that may correlate with cognitive changes associated with acute mTBI...
2018: PloS One
https://www.readbyqxmd.com/read/29406019/community-reintegration-participation-and-employment-issues-in-veterans-and-service-members-with-traumatic-brain-injury
#10
Christina Dillahunt-Aspillaga, Gail Powell-Cope
Traumatic brain injury (TBI) has been called the signature injury of the post-9/11 wars in Iraq, Afghanistan, and neighboring countries. Although similarities exist between veterans and service members with TBI, levels of severity and different constellations of coexisting comorbid conditions affect them differently. These conditions affect physical, cognitive, and emotional function, which in turn can complicate community reintegration (CR), or the ability to return to family, vocational, and community life...
February 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29355429/the-effects-of-post-traumatic-depression-on-cognition-pain-fatigue-and-headache-after-moderate-to-severe-traumatic-brain-injury-a-thematic-review
#11
R G Kumar, S Gao, S B Juengst, A K Wagner, A Fabio
BACKGROUND: Post-traumatic depression (PTD) is one of the most common secondary complications to develop after moderate-to-severe traumatic brain injury (TBI). However, it rarely manifests singularly, and often co-occurs with other common TBI impairments. OBJECTIVE: The objective of this thematic review is to evaluate studies examining the relationships between PTD and cognition, fatigue, pain, and headache among individuals with moderate-to-severe TBI. RESULTS: We reviewed 16 studies examining the relationship between PTD and cognition (five articles), fatigue (five articles), pain (four articles), and headache (two articles)...
2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29345192/cross-validation-of-the-dot-counting-test-in-a-large-sample-of-credible-and-non-credible-patients-referred-for-neuropsychological-testing
#12
Courtney McCaul, Kyle B Boone, Annette Ermshar, Maria Cottingham, Tara L Victor, Elizabeth Ziegler, Michelle A Zeller, Matthew Wright
OBJECTIVE: To cross-validate the Dot Counting Test in a large neuropsychological sample. METHOD: Dot Counting Test scores were compared in credible (n = 142) and non-credible (n = 335) neuropsychology referrals. RESULTS: Non-credible patients scored significantly higher than credible patients on all Dot Counting Test scores. While the original E-score cut-off of ≥17 achieved excellent specificity (96.5%), it was associated with mediocre sensitivity (52...
January 18, 2018: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/29310710/photobiomodulation-using-low-level-laser-therapy-lllt-for-patients-with-chronic-traumatic-brain-injury-a-randomized-controlled-trial-study-protocol
#13
Guilherme da Cruz Ribeiro Poiani, Ana Luiza Zaninotto, Ana Maria Costa Carneiro, Renato Amaro Zangaro, Afonso Shiguemi Inoue Salgado, Rodolfo Borges Parreira, Almir Ferreira de Andrade, Manoel Jacobsen Teixeira, Wellingson Silva Paiva
BACKGROUND: Photobiomodulation using low-level laser therapy (LLLT) has been tested as a new technique to optimize recovery of patients with traumatic brain injury (TBI). The aim of this study is to evaluate inhibitory attentional control after 18 sessions of active LLLT and compare with the placebo group (sham LLLT). Our exploratory analysis will evaluate the efficacy of the active LLLT on verbal and visuospatial episodic memory, executive functions (working memory, verbal and visuospatial fluency, attentional processes), and anxiety and depressive symptoms compared to the sham group...
January 8, 2018: Trials
https://www.readbyqxmd.com/read/29283307/using-the-california-verbal-learning-test-second-edition-as-an-embedded-performance-validity-measure-among-individuals-with-tbi-and-individuals-with-psychiatric-disorders
#14
Virginia C Persinger, Douglas M Whiteside, Lyuba Bobova, Seema D Saigal, Marla J Vannucci, Michael R Basso
OBJECTIVE: Among embedded performance validity tests (PVTs), little research addresses the use of Total Hits and Total False Positives from the California Verbal Learning Test, Second Edition (CVLT-II) in spite of low sensitivity, particularly in psychiatric samples. METHOD: This study examined the classification accuracy of these two measures in individuals with psychiatric disorders or mild traumatic brain injury (MTBI). These samples were separated into two groups using the criteria of passing all PVTs versus failing 2 or more PVTs...
December 28, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/29239267/a-retrospective-study-of-predictors-of-return-to-duty-versus-medical-retirement-in-an-active-duty-military-population-with-blast-related-mild-traumatic-brain-injury
#15
Philip A Cook, Thomas M Johnson, Suzanne G Martin, Philip R Gehrman, Seema Bhatnagar, James C Gee
Traumatic Brain Injury (TBI) has been described as the "signature injury" of the Global War on Terror. Explosive blast TBI has become a leading cause of injury as a result of the widespread use of improvised explosive devices in Iraq and Afghanistan. We present a retrospective cross-sectional study of patients with blast-related mild TBI (mTBI, N = 303) seen at the Intrepid Spirit Concussion Recovery Center at Naval Medical Center Camp Lejeune. The objective was to predict outcomes of return to duty (RTD) vs...
March 1, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29210077/estimating-verbal-fluency-and-naming-ability-from-the-test-of-premorbid-functioning-and-demographic-variables-regression-equations-derived-from-a-regional-uk-sample
#16
Toni-Marie Jenkinson, Steven Muncer, Miranda Wheeler, Don Brechin, Stephen Evans
OBJECTIVES: Neuropsychological assessment requires accurate estimation of an individual's premorbid cognitive abilities. Oral word reading tests, such as the test of premorbid functioning (TOPF), and demographic variables, such as age, sex, and level of education, provide a reasonable indication of premorbid intelligence, but their ability to predict other related cognitive abilities is less well understood. This study aimed to develop regression equations, based on the TOPF and demographic variables, to predict scores on tests of verbal fluency and naming ability...
December 6, 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29198271/the-neuropsychology-of-traumatic-brain-injury-looking-back-peering-ahead
#17
Keith Owen Yeates, Harvey S Levin, Jennie Ponsford
The past 50 years have been a period of exciting progress in neuropsychological research on traumatic brain injury (TBI). Neuropsychologists and neuropsychological testing have played a critical role in these advances. This study looks back at three major scientific advances in research on TBI that have been critical in pushing the field forward over the past several decades: The advent of modern neuroimaging; the recognition of the importance of non-injury factors in determining recovery from TBI; and the growth of cognitive rehabilitation...
October 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29168451/intraindividual-cognitive-variability-an-examination-of-anam4-tbi-mil-simple-reaction-time-data-from-service-members-with-and-without-mild-traumatic-brain-injury
#18
Wesley R Cole, Emma Gregory, Jacques P Arrieux, F Jay Haran
OBJECTIVES: The Automated Neuropsychological Assessment Metrics 4 TBI-MIL (ANAM4) is a computerized cognitive test often used in post-concussion assessments with U.S. service members (SMs). However, existing evidence remains mixed regarding ANAM4's ability to identify cognitive issues following mild traumatic brain injury (mTBI). Studies typically examine ANAM4 using standardized scores and/ or comparisons to a baseline. A more fine-grained approach involves examining inconsistency within an individual's performance (i...
February 2018: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29152209/case-control-study-hyperbaric-oxygen-treatment-of-mild-traumatic-brain-injury-persistent-post-concussion-syndrome-and-post-traumatic-stress-disorder
#19
Paul G Harch, Susan R Andrews, Edward F Fogarty, Juliette Lucarini, Keith W Van Meter
Mild traumatic brain injury (TBI) persistent post-concussion syndrome (PPCS) and post-traumatic stress disorder (PTSD) are epidemic in United States Iraq and Afghanistan War veterans. Treatment of the combined diagnoses is limited. The aim of this study is to assess safety, feasibility, and effectiveness of hyperbaric oxygen treatments (HBOT) for mild TBI PPCS and PTSD. Thirty military subjects aged 18-65 with PPCS with or without PTSD and from one or more blast-induced mild-moderate traumatic brain injuries that were a minimum of 1 year old and occurred after 9/11/2001 were studied...
July 2017: Medical Gas Research
https://www.readbyqxmd.com/read/29072086/a-pilot-randomized-controlled-trial-of-on-line-interventions-to-improve-sleep-quality-in-adults-after-mild-or-moderate-traumatic-brain-injury
#20
Alice Theadom, Suzanne Barker-Collo, Kelly Jones, Margaret Dudley, Norah Vincent, Valery Feigin
OBJECTIVE: To explore feasibility and potential efficacy of on-line interventions for sleep quality following a traumatic brain injury (TBI). DESIGN: A two parallel-group, randomized controlled pilot study. SETTING: Community-based. SUBJECTS: In all, 24 participants (mean age: 35.9 ± 11.8 years) who reported experiencing sleep difficulties between 3 and 36 months after a mild or moderate TBI. INTERVENTIONS: Participants were randomized to receive either a cognitive behaviour therapy or an education intervention on-line...
October 1, 2017: Clinical Rehabilitation
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