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https://www.readbyqxmd.com/read/28332218/changes-in-myocardial-deformation-after-transcatheter-and-surgical-aortic-valve-replacement
#1
REVIEW
Vinisha Garg, Jonathan K Ho, Gabriel Vorobiof
Speckle tracking echocardiography (STE) has emerged as a novel angle-independent modality in assessing myocardial velocity, deformation, and strain. Its role in assessing change before and after aortic valve replacement in patients with aortic stenosis (AS) has recently generated interest. This review summarizes the practical utility and clinical implications of myocardial deformation by STE after surgical or transcatheter aortic valve replacement (TAVR). Overall, atrial strain and ventricular strain as measured by STE improve after surgical and transcatheter aortic intervention in short- and long-term follow-up with evidence of a more pronounced acute improvement in patients who undergo TAVR...
March 23, 2017: Echocardiography
https://www.readbyqxmd.com/read/28332215/effects-of-increased-left-ventricular-wall-thickness-on-the-myocardium-in-severe-aortic-stenosis-with-normal-left-ventricular-ejection-fraction-two-and-three-dimensional-multilayer-speckle-tracking-echocardiography
#2
Eun Jeong Cho, Sung-Ji Park, Eun Kyoung Kim, Ga Yeon Lee, Sung-A Chang, Jin-Oh Choi, Sang-Chol Lee, Seung Woo Park
BACKGROUND: The aim of this study was to determine the capability of real time three-dimensional echocardiography (RT3DE) and two-dimensional (2D) multilayer speckle tracking echocardiography (MSTE) for evaluation of early myocardial dysfunction triggered by increased left ventricular (LV) wall thickness in severe aortic stenosis (AS) with normal LV ejection fraction (EF≥55%). METHODS: Conventional, RT3D STE and 2D MSTE were performed in 45 patients (mean 68.9±9...
March 23, 2017: Echocardiography
https://www.readbyqxmd.com/read/28331157/the-usefulness-of-combined-assessment-of-e-e-ratio-and-transmitral-flow-pattern-to-interpret-cardiac-condition
#3
Masayoshi Oikawa, Atsushi Kobayashi, Takamasa Sato, Satoshi Suzuki, Yoshihisa Akiomi, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-Ichi Saitoh, Yasuchika Takeishi
High mitral inflow early (E) velocity to tissue Doppler E' ratio (E/E') and an E to late diastolic filling velocity ratio (E/A) are used to evaluate left ventricular (LV) diastolic function and filling pressure, but the usefulness of combined assessment of E/E' and E/A is not fully understood. Methods: We retrospectively analyzed 1,266 patients who underwent echocardiography to assess cardiac function. Patients were grouped based on the values of E/E' (low E/E'<15, high E/E'≥15) and E/A (low E/A≤0...
March 22, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28329333/pre-and-postoperative-tricuspid-regurgitation-in-patients-with-severe-symptomatic-aortic-stenosis-importance-of-pre-operative-tricuspid-annulus-diameter
#4
Claire Dumont, Elena Galli, Emmanuel Oger, Maxime Fournet, Erwan Flecher, Christophe Leclercq, Jean-Philippe Verhoye, Erwan Donal
Aims: Secondary tricuspid regurgitation (STR) is commonly found in patients with aortic stenosis and is associated with increased morbidity. The study sought to evaluate the prevalence of pre-operative STR and its progression after surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI). Also, it sought to analyse the predictors of post-operative changes in STR. Methods and results: We prospectively evaluated 116 patients (aged 75...
March 7, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28329137/association-of-left-atrial-structure-and-function-and-incident-cardiovascular-disease-in-patients-with-diabetes-mellitus-results-from-multi-ethnic-study-of-atherosclerosis-mesa
#5
Timothy M Markman, Mohammadali Habibi, Bharath Ambale Venketash, Mytra Zareian, Colin Wu, Susan R Heckbert, David A Bluemke, Joao A C Lima
Aims: Diabetes mellitus (DM) is associated with the development of cardiovascular disease (CVD). Morphological changes in the left atrium (LA) may appear before symptoms. We aimed to investigate the association between cardiac magnetic resonance imaging (CMR) measured LA structure and function and incident CVD in asymptomatic individuals with DM. Methods and results: Tissue tracking CMR was used to measure LA size and phasic function (emptying fractions and strain) on all 536 Multi-Ethnic Study of Atherosclerosis (MESA) participants with DM and available CMR at baseline in 2000-2002...
February 28, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28329042/longitudinal-cardiovascular-outcomes-of-sleep-disordered-breathing-in-children-a-meta-analysis-and-systematic-review
#6
Zarmina Ehsan, Stacey L Ishman, Thomas R Kimball, Nanhua Zhang, Yuanshu Zou, Raouf S Amin
Objectives: The presence of sleep disordered breathing (SDB) is known to impact long-term cardiovascular morbidity in adults; however, the long-term effects in children are poorly understood. We aimed to systematically review and synthesize studies published to date on the long-term effects of SDB in children. Study Design: Meta-analysis and systematic review using PubMed, CINAHL,Embase and Scopus (all indexed years). Methods: We searched for English-language articles containing original human data from prospective studies, with ≥7 participants, in children ≤18 years of age...
January 28, 2017: Sleep
https://www.readbyqxmd.com/read/28327874/left-atrial-deformation-analysis-in-patients-with-corrected-tetralogy-of-fallot-by-3d-speckle-tracking-echocardiography-from-the-magyar-path-study
#7
Kálmán Havasi, Péter Domsik, Anita Kalapos, Jackie S McGhie, Jolien W Roos-Hesselink, Tamás Forster, Attila Nemes
Background: Three-dimensional (3D) echocardiography coupled with speckle-tracking echocardiographic (STE) capability is a novel methodology which has been demontrated to be useful for the assessment of left atrial (LA) volumes and functional properties. There is increased scientific interest on myocardial deformation analysis in adult patients with corrected tetralogy of Fallot (cTOF). Objectives: To compare LA volumes, volume-based functional properties and strain parameters between cTOF patients and age- and gender-matched healthy controls...
February 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28325614/gothic-aortic-arch-and-cardiac-mechanics-in-young-patients-after-arterial-switch-operation-for-d-transposition-of-the-great-arteries
#8
Giovanni Di Salvo, Ziad Bulbul, Valeria Pergola, Ziad Issa, Ghassan Siblini, Nisreen Muhanna, Domenico Galzerano, Bahaa Fadel, Mansour Al Joufan, Majid Al Fayyadh, Zohair Al Halees
BACKGROUND: In patients who have undergone arterial switch operation (ASO) for d-transposition of the great arteries a gothic aortic arch (GA) morphology has been found and it has been associated with abnormal aortic bio-elastic properties. HYPOTHESIS: GA is frequent in ASO patients and may have an impact on cardiac mechanics. Our study aims were to assess 1- the occurrence of GA in a large sample of patients after ASO; 2- the association between GA and aortic bio-elastic properties; and 3- the impact of GA on left ventricular (LV) function using speckle tracking echocardiography (STE)...
March 11, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28325569/transcatheter-aortic-valve-implantation-in-patients-with-advanced-chronic-kidney-disease
#9
Federico Conrotto, Stefano Salizzoni, Alessandro Andreis, Fabrizio D'Ascenzo, Augusto D'Onofrio, Marco Agrifoglio, Alaide Chieffo, Antonio Colombo, Filippo Rapetto, Francesco Santini, Giuseppe Tarantini, Davide Gabbieri, Carlo Savini, Sebastiano Immè, Flavio Ribichini, Orazio Valsecchi, Marco Aiello, Giovanni Lixi, Alessandro Iadanza, Esmeralda Pompei, Miroslava Stolcova, Diego Ornaghi, Alessandro Minati, Mauro Cassese, Gian Luca Martinelli, Pierluigi Sbarra, Andrea Agostinelli, Andrea Audo, Andrea Pieroni, Rosario Fiorilli, Gino Gerosa, Mauro Rinaldi, Fiorenzo Gaita
Advanced chronic kidney disease (CKD) is associated with poor outcomes in patients who underwent surgical aortic valve replacement, whereas its prognostic role in transcatheter aortic valve implantation (TAVI) remains unclear. This study aimed to investigate outcomes in patients with advanced CKD who underwent TAVI. A total of 1,904 consecutive patients who underwent balloon-expandable TAVI in 33 centers between 2007 and 2012 were enrolled in the Italian Transcatheter Balloon-Expandable Valve Implantation Registry...
February 10, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28325518/the-impact-of-age-and-gender-on-right-ventricular-diastolic-function-among-healthy-adults
#10
Antonello D'Andrea, Olga Vriz, Andreina Carbone, Francesco Ferrara, Marco Di Maio, Rosangela Cocchia, Gianluigi Tagliamonte, Edwige Acri, Caterina Driussi, Enrica Pezzullo, Rodolfo Citro, Antonio Cittadini, Raffaele Calabrò, Maria Giovanna Russo, Eduardo Bossone
BACKGROUND: Doppler echocardiography is ideally suited for assessment of diastolic function, being widely available, non-invasive, and less expensive than other techniques. However, data regarding age- and gender-matched reference values of right ventricular diastolic function are limited. This study aims to explore the physiologic variations of right ventricle (RV) diastolic function in a large cohort of healthy adults, and to investigate clinical and echocardiographic correlates. METHODS: From June 2007 to February 2014, 1168 healthy Caucasian subjects [mean age 45...
March 18, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28322592/intravascular-pulmonary-venous-ultrasound-imaging-for-catheter-ablation-of-atrial-fibrillation
#11
Gabriel Cismaru, Serban Schiau, Lucian Muresan, Radu Rosu, Mihai Puiu, Dana Pop, Dumitru Zdrenghea
Atrial fibrillation is the most common cardiac arrhythmia. The development of electroanatomical mapping is an increase demand for advanced intracardiac imaging techniques of the left atrium and pulmonary veins. IVUS can demonstrate quantitative changes like lumen and wall thickness as well as qualitative changes of the pulmonary or coronary arteries wall. IVUS could also provide relevant real time imaging of the atrial and pulmonary venous wall during catheter ablation. Areas covered: The Medline and Embase databases were searched for preclinical and clinical studies of IVUS in patients with ablation of atrial fibrillation or left atrial arrhythmias...
March 21, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28320316/clinical-outcomes-of-conventional-surgery-versus-mitraclip%C3%A2-therapy-for-moderate-to-severe-symptomatic-mitral-valve-regurgitation-in-the-elderly-population-an-institutional-experience
#12
Anthony Alozie, Liliya Paranskaya, Bernd Westphal, Alexander Kaminski, Mohammad Sherif, Magnus Sindt, Stephan Kische, Jochen Schubert, Doreen Diedrich, Hüseyin Ince, Gustav Steinhoff, Alper Öner
BACKGROUND: The aim of this study was to compare treatment of moderate to severe symptomatic mitral regurgitation (MR) with either conventional surgery or the mitral valve edge-to-edge device (MitraClip®) in very elderly patients. The newly introduced MitraClip device has demonstrated promising acute results in treating this patient cohort. Also noteworthy is the fact that patients who otherwise would have been denied surgery are increasingly referred for treatment with the MitraClip device...
March 20, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28319522/a-numerical-simulation-comparing-a-cavopulmonary-assist-device-and-va-ecmo-for-failing-fontan-support
#13
Po-Lin Hsu, Dongfang Wang, Cherry Ballard-Croft, Dawei Xiao, Joseph B Zwischenberger
A cavopulmonary assist device (CPAD) has been developed for failing Fontan support. This CPAD pumps blood from superior/inferior vena cavae to pulmonary artery. In this study, we compared failing Fontan support with CPAD versus VA ECMO in silico. A numerical lumped-parameter circulatory system model was used to simulate Fontan circulation. Failing Fontan was simulated by increased pulmonary resistance. Central venous pressure (CVP), mean pulmonary arterial pressure (mPAP), left atrial pressure (LAP), and univentricular outflow (CO) were simulated and compared to published clinical data...
March 17, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28318656/clinical-characteristics-and-prognosis-of-patients-admitted-for-heart-failure-a-5-year-retrospective-study-of-african-patients
#14
Kwadwo Osei Bonsu, Isaac Kofi Owusu, Kwame Ohene Buabeng, Daniel D Reidpath, Amudha Kadirvelu
BACKGROUND: Mortality associated with heart failure (HF) remains high. There are limited clinical data on mortality among HF patients from African populations. We examined the clinical characteristics, long-term outcomes, and prognostic factors of African HF patients with preserved, mid-range or reduced left ventricular ejection fraction (LVEF). METHODS AND RESULTS: We conducted a retrospective longitudinal cohort study of individuals aged ≥18years discharged from first HF admission between January 1, 2009 and December 31, 2013 from the Cardiac Clinic, Directorate of Medicine of the Komfo Anokye Teaching Hospital, Ghana...
March 6, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28317155/evaluation-of-the-effect-of-dipping-pattern-in-hypertensive-patients-on-the-left-ventricular-systolic-functions-by-two-dimensional-strain-analysis
#15
Hüseyin Göksülük, Ulvin Habibova, Aydan Ongun, Müge Akbulut, Nil Özyüncü, Türkan Seda Tan Kürklü, Cetin Erol
BACKGROUND: Nondipping blood pressure pattern carry a high risk of cardiovascular and cerebrovascular complications due to a higher cumulative pressure overload. We aimed to define the role of strain analysis for detecting subclinical left ventricular systolic dysfunction in recently diagnosed nondipper and dipper hypertensive patients with normal left ventricular systolic function. METHODS: Study population consisted of two groups of patients, Group 1: 45 dipper patients and Group 2: 43 nondipper patients...
March 19, 2017: Echocardiography
https://www.readbyqxmd.com/read/28314925/evaluation-of-left-ventricular-functions-in-patients-with-primary-hyperparathyroidism-is-there-any-effect-of-parathyroidectomy
#16
Alper Kepez, Mehmet Yasar, Murat Sunbul, Cigdem Ileri, Oguzhan Deyneli, Bulent Mutlu, Osman Yesildag, Yelda Basaran
PURPOSE: Our aim was to evaluate left ventricular (LV) systolic and diastolic functions of primary hyperparathyroidism (pHPT) patients with detailed echocardiographic analysis and investigate the effect of parathyroidectomy on echocardiographic parameters. METHODS: A total of 22 eligible consecutive patients with pHPT who underwent parathyroidectomy operation were recruited to the study. Another 22 subjects with similar age, gender and frequency of cardiovascular risk factors compared to patients were used as a control group...
March 17, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/28314622/diastolic-function-and-transcatheter-aortic-valve-replacement
#17
John E A Blair, Prashant Atri, Julie L Friedman, James D Thomas, Kent Brummel, Ranya N Sweis, Issam Mikati, S Chris Malaisrie, Charles J Davidson, James D Flaherty
BACKGROUND: Little is known about baseline diastolic dysfunction and changes in diastolic dysfunction grade after transcatheter aortic valve replacement (TAVR) for aortic stenosis (AS) and its impact on overall outcomes. The aim of this study was to describe baseline diastolic dysfunction and changes in diastolic dysfunction grade that occur with TAVR and their relationship to mortality and rehospitalization. METHODS: This was a single-center study evaluating all TAVRs from January 2012 to June 2014...
March 14, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28314614/presumptive-partial-atrial-standstill-secondary-to-atrial-cardiomyopathy-in-a-greyhound
#18
S Wesselowski, J Abbott, M Borgarelli, M Tursi
Persistent atrial standstill is a rare arrhythmia in both human and veterinary patients. In recent decades, cases of partial atrial standstill have been recognized in humans. We describe a case of presumptive partial atrial standstill in a Greyhound, in which there was disparate left and right atrial electromechanical function and rapid progression to congestive heart failure over the span of fourteen weeks. An atrial cardiomyopathy characterized by severe, diffuse, fibrofatty replacement of the atrial myocardium was identified histologically...
March 14, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/28303410/downregulation-of-myogenic-micrornas-in-sub-chronic-but-not-in-sub-acute-model-of-daunorubicin-induced-cardiomyopathy
#19
Gabriel Doka, Eva Malikova, Kristina Galkova, Giampiero La Rocca, Peter Kruzliak, Mariusz Adamek, Luis Rodrigo, Peter Krenek, Jan Klimas
Cardiac muscle-related microRNAs play important roles in cardiac development and disease by translational silencing of mRNAs, the dominant mechanism of microRNA action. To test whether they could be involved in daunorubicin-associated cardiomyopathy (DACM), we determined expression patterns of myomiRs in two distinct models of DACM. We used 10-12 weeks old male Wistar rats. In the sub-acute model, rats were administered with six doses of daunorubicin (DAU-A, 3 mg/kg, i.p., every 48 h). Rats were sacrificed two days after the last dose...
March 16, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28302294/a-test-in-context-e-a-and-e-e-to-assess-diastolic-dysfunction-and-lv-filling-pressure
#20
REVIEW
Sumeet S Mitter, Sanjiv J Shah, James D Thomas
Diastolic dysfunction represents a combination of impaired left ventricular (LV) relaxation, restoration forces, myocyte lengthening load, and atrial function, culminating in increased LV filling pressures. Current Doppler echocardiography guidelines recommend using early to late diastolic transmitral flow velocity (E/A) to assess diastolic function, and E to early diastolic mitral annular tissue velocity (E/e') to estimate LV filling pressures. Although both parameters have important diagnostic and prognostic implications, they should be interpreted in the context of a patient's age and the rest of the echocardiogram to describe diastolic function and guide patient management...
March 21, 2017: Journal of the American College of Cardiology
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