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synovitis,ultrasound

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https://www.readbyqxmd.com/read/28644744/add-on-iguratimod-as-a-therapeutic-strategy-to-achieve-remission-in-patients-with-rheumatoid-arthritis-inadequately-responding-to-biological-dmards-a-retrospective-study
#1
Ayaka Yoshikawa, Shuzo Yoshida, Yuko Kimura, Nao Tokai, Yohei Fujiki, Takuya Kotani, Yoko Matsumura, Tohru Takeuchi, Shigeki Makino
OBJECTIVES: In this study, iguratimod (IGU) was added to rheumatoid arthritis (RA) patients inadequately responding to 24-week or longer treatment with biological disease-modifying antirheumatic drug (bDMARDs), its effectiveness was assessed, and factors contributing to remission were evaluated. METHODS: RA patients who fulfilled the following criteria were included: (i) ≥ 24-week of bDMARDs; (ii) 2.6 < disease activity score (DAS) 28-erythrocyte sedimentation rate (ESR) < 5...
June 23, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28638684/the-new-acr-eular-criteria-for-rheumatoid-arthritis-can-identify-patients-with-same-disease-activity-but-less-damage-by-ultrasound
#2
Sibel Zehra Aydın, Concepcion Castillo-Gallego, Jackie Nam, Jane Freeston, Sarah Horton, Richard J Wakefield, Paul Emery
OBJECTIVE: We aimed to compare the ultrasound findings of patients fulfilling the 1987 ACR [OLD-rheumatoid arthritis (RA)] and the new ACR/EULAR (NEW-RA) classification criteria to examine the impact of the new criteria on disease characteristics, particularly disease duration. MATERIAL AND METHODS: A total of 2730 hands, wrists, elbows, knees, ankles, and foot joints of 105 consecutive patients with inflammatory arthritis, i.e., 82 patients fulfilling the RA criteria (60 patients, OLD-RA; 22 patients, NEW-RA alone) and 23 patients with undifferentiated arthritis, were scanned using ultrasound...
June 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28602490/ultrasound-findings-on-hands-and-wrists-of-patients-with-systemic-lupus-erythematosus-relationship-with-physical-examination
#3
Carolina Freitas Lins, Daniel Lima de Sá Ribeiro, Willer Gonçalves Dourado Santos, Genevievi Rosa, Viviane Machicado, Ana Luisa Pedreira, Emanuela Pimenta da Fonseca, Anna Paula Mota Duque Sousa, Carla Baleeiro Rodrigues Silva, Marcos Antonio Almeida Matos, Mittermayer Barreto Santiago
Diagnosis of synovitis/tenosynovitis by physical examination can be difficult. Ultrasound (US) can be an effective tool for the evaluation of joint involvement in systemic lupus erythematosus (SLE). This study will describe musculoskeletal findings by US in SLE patients and the evaluation of their correlation with physical examination. SLE patients underwent clinical/sonographic evaluation of hand/wrists. In total, 896 joints were evaluated: at least 1 change on physical examination was found in 136 joints and at least 1 US abnormality was found in 65 of 896 joints...
June 8, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28549731/clinical-and-sonographic-biomarkers-of-structural-damage-progression-in-ra-patients-in-clinical-remission-a-prospective-study-with-12-months-follow-up
#4
Julio Ramírez, José Antonio Narváez, Virginia Ruiz-Esquide, Javier Hernández-Gañán, Andrea Cuervo, José Inciarte-Mundo, Maria Victoria Hernández, Miguel Sampayo-Cordero, José Luis Pablos, Raimon Sanmartí, Juan D Cañete
OBJECTIVE: To determine clinical and sonographic biomarkers predicting structural damage progression at 12 months of follow-up as measured by magnetic resonance imaging (MRI) in rheumatoid arthritis (RA) patients in clinical remission. PATIENTS AND METHODS: We included patients with RA in clinical remission, defined as 28-joint disease activity score (DAS28)-erythrocyte sedimentation rate (ESR) <2.6 for >6 months. Ultrasound scans of both hands and knees and MRI of the dominant hand were performed at baseline and at 12 months...
May 1, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28545509/ultrasound-detected-bone-erosion-is-a-relapse-risk-factor-after-discontinuation-of-biologic-disease-modifying-antirheumatic-drugs-in-patients-with-rheumatoid-arthritis-whose-ultrasound-power-doppler-synovitis-activity-and-clinical-disease-activity-are-well
#5
Shin-Ya Kawashiri, Keita Fujikawa, Ayako Nishino, Akitomo Okada, Toshiyuki Aramaki, Toshimasa Shimizu, Masataka Umeda, Shoichi Fukui, Takahisa Suzuki, Tomohiro Koga, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Akinari Mizokami, Hideki Nakamura, Tomoki Origuchi, Yukitaka Ueki, Kiyoshi Aoyagi, Takahiro Maeda, Atsushi Kawakami
BACKGROUND: In the present study, we explored the risk factors for relapse after discontinuation of biologic disease-modifying antirheumatic drug (bDMARD) therapy in patients with rheumatoid arthritis (RA) whose ultrasound power Doppler (PD) synovitis activity and clinical disease activity were well controlled. METHODS: In this observational study in clinical practice, the inclusion criteria were based on ultrasound disease activity and clinical disease activity, set as low or remission (Disease Activity Score in 28 joints based on erythrocyte sedimentation rate <3...
May 25, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28539973/are-ultrasound-features-at-the-first-metatarsophalangeal-joint-associated-with-clinically-assessed-pain-and-function-a-study-of-people-with-gout-asymptomatic-hyperuricaemia-and-normouricaemia
#6
Sarah Stewart, Nicola Dalbeth, Alain C Vandal, Bruce Allen, Rhian Miranda, Keith Rome
BACKGROUND: The first metatatarsophalangeal joint (1st MTP joint) is a common location for sonographic evidence of urate deposition in people with gout and asymptomatic hyperuricaemia. However, it is unclear whether these are related to clinically-assessed pain and function. This study aimed to determine the association between ultrasound features and clinical characteristics of the 1st MTP joint in people with gout, asymptomatic hyperuricaemia and age- and sex-matched normouricaemic individuals...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/28521689/relationship-between-rheumatoid-arthritis-disease-activity-assessed-with-the-us7-score-and-quality-of-life-measured-with-questionnaires-haq-eq-5d-wpai
#7
Martina Skácelová, Skácelová Martina, Horák Pavel, Heřmanová Zuzana, Langová Kateřina
BACKGROUND: Rheumatoid arthritis is a chronic disease considerably affecting the quality of life of patients, their functional abilities and capability to work. In everyday clinical practice, the condition is commonly monitored by assessing the disease activity using a joint count and laboratory markers of inflammation with calculating the DAS28 or other systems for scoring the disease activity. OBJECTIVES: This study is aimed to evaluate the benefit of ultrasound examination with a standardized instrument and correlate its results with the quality of life of patients and their functional abilities as assessed by standardized questionnaire methods...
May 17, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28516887/tenosynovitis-in-rheumatoid-arthritis-patients-on-biologic-treatment-involvement-and-sensitivity-to-change-compared-to-joint-inflammation
#8
Hilde Berner Hammer, Tore K Kvien, Lene Terslev
OBJECTIVES: Extensor carpi ulnaris (ECU) and tibialis posterior (TP) tendons are often involved in RA and the present aim was to examine by ultrasound (US) their frequency of inflammation and sensitivity to change in comparison to joint involvement as well as clinical examinations. METHODS: US, clinical and laboratory assessments were performed when starting biologic DMARD (bDMARD) and after 1, 2, 3, 6 and 12 months including bilateral grey-scale (GS) and power Doppler (PD) semi-quantitatively (0-3) scoring of ECU and TP tendons and 18 joints...
May 15, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28477219/reliability-of-ultrasound-grading-traditional-score-and-new-global-omeract-eular-score-system-gloess-results-from-an-inter-and-intra-reading-exercise-by-rheumatologists
#9
Lucio Ventura-Ríos, Cristina Hernández-Díaz, Diana Ferrusquia-Toríz, Esteban Cruz-Arenas, Pedro Rodríguez-Henríquez, Ana Laura Alvarez Del Castillo, Alfredo Campaña-Parra, Efrén Canul, Gerardo Guerrero Yeo, Juan Jorge Mendoza-Ruiz, Mario Pérez Cristóbal, Sandra Sicsik, Karina Silva Luna
This study aims to test the reliability of ultrasound to graduate synovitis in static and video images, evaluating separately grayscale and power Doppler (PD), and combined. Thirteen trained rheumatologist ultrasonographers participated in two separate rounds reading 42 images, 15 static and 27 videos, of the 7-joint count [wrist, 2nd and 3rd metacarpophalangeal (MCP), 2nd and 3rd interphalangeal (IPP), 2nd and 5th metatarsophalangeal (MTP) joints]. The images were from six patients with rheumatoid arthritis, performed by one ultrasonographer...
May 5, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28471034/ultrasonography-detected-subclinical-inflammation-in-patients-with-hand-osteoarthritis-and-established-rheumatoid-arthritis-a-comparison-between-two-different-pathologies-using-the-same-ultrasound-examination-protocol
#10
Sidra Hussain, Priyanka Sivakumaran, Anna Gill, Delfin Dhas, Coziana Ciurtin
OBJECTIVES: A recent review of ultrasound (US) studies in osteoarthritis (OA) showed very limited data about hand OA. Previous US studies in patients with OA described a degree of overlap between the US appearance of rheumatoid arthritis (RA) and OA joints. The present study aimed to assess the US features of subclinical inflammation in RA and hand OA, using the same US examination protocol. METHODS: A retrospective, cohort study compared patients with established RA (n = 224) and hand OA (n = 73), with respect to several demographic, clinical, laboratory and US parameters...
May 4, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/28469936/ultrasound-detectable-grey-scale-synovitis-predicts-future-fulfilment-of-the-2010-acr-eular-ra-classification-criteria-in-patients-with-new-onset-undifferentiated-arthritis
#11
Sarah C Horton, Ai Lyn Tan, Richard J Wakefield, Jane E Freeston, Maya H Buch, Paul Emery
OBJECTIVE: To determine the clinical outcomes for patients with new-onset undifferentiated arthritis (UA), not fulfilling the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) rheumatoid arthritis (RA) classification criteria, and the clinical and imaging predictors of disease progression in these patients. METHODS: A prospective observational study was conducted in treatment-naïve UA patients. Baseline ultrasound involved semiquantitative assessment of grey scale (GS) synovitis and power Doppler activity (PD) at 26 joints...
2017: RMD Open
https://www.readbyqxmd.com/read/28461647/utility-of-power-doppler-ultrasound-detected-synovitis-for-the-prediction-of-short-term-flare-in-psoriatic-patients-with-arthritis-in-clinical-remission
#12
Santiago Ruta, Josefina Marin, Maria Laura Acosta Felquer, Leandro Ferreyra-Garrot, Javier Rosa, Ricardo García-Monaco, Enrique R Soriano
OBJECTIVE: Power Doppler ultrasound (PDUS) has been shown to detect subclinical synovitis in psoriatic arthritis (PsA), but its value is not yet fully understood. The aim of this study was to evaluate PDUS features at joint level in patients with PsA in clinical remission and to investigate its value for predicting short-term flares. METHODS: Consecutive patients with PsA in clinical remission according to the attending rheumatologist and who fulfill minimal disease activity criteria and/or 28-joint Disease Activity Score in remission criteria underwent PDUS examination of 18 joints...
May 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28438383/remitting-seronegative-symmetrical-synovitis-with-pitting-edema-rs3pe-syndrome-induced-by-nivolumab
#13
Marie-Léa Gauci, Barouyr Baroudjian, Pauline Laly, Isabelle Madelaine, Laetitia Da Meda, Laetitia Vercellino, Martine Bagot, Frédéric Lioté, Cécile Pages, Céleste Lebbé
INTRODUCTION: A new articular syndrome described as immunrelated side effect of immunotherapy: PD-1 inhibitors have revolutionized the treatment of advanced melanoma but are responsible for immune-related toxicity. We report a case of remitting seronegative symetrical synovitis with pitting edema (RS3PE) syndrome induced by nivolumab. CASE REPORT: A 80 year-old man with stage IV BRAF-wild type and NRAS exon 2-mutated melanoma was treated first line by nivolumab 3mg/kg every 2 weeks...
March 8, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28431182/joint-positions-matter-for-ultrasound-examination-of-ra-patients-increased-power-doppler-signal-in-neutral-versus-flat-position-of-hands
#14
Rusmir Husic, Angelika Lackner, Martin H Stradner, Josef Hermann, Christian Dejaco
Objective.: Position of joints might influence the result of US examination in patients with RA. The purpose of this work was to compare grey-scale (GS) and power Doppler (PWD) findings obtained in neutral vs flat position of hands. Methods.: A cross-sectional study of 42 RA patients with active disease. Two dimensional and 3D sonography of wrists and MCP joints were conducted in two different joint positions: neutral position, which is a slight flexion of the fingers with relaxed extensor muscles; and flat position, where all palm and volar sides of fingers touch the Table...
April 18, 2017: Rheumatology
https://www.readbyqxmd.com/read/28428648/ultrasound-of-ankles-in-the-diagnosis-of-complications-of-chikungunya-fever
#15
Roberto Mogami, João Luiz Pereira Vaz, Yêdda de Fátima Barcelos Chagas, Rodrigo Sperling Torezani, André de Almeida Vieira, Ana Célia Baptista Koifman, Yasmin Baptista Barbosa, Mirhelen Mendes de Abreu
OBJECTIVE: To describe the main ultrasound findings of chikungunya fever in the ankle. MATERIALS AND METHODS: This was a cross-sectional observational study involving 52 patients referred to the Hospital Universitário Pedro Ernesto and presenting with clinical and biochemical evidence of chikungunya fever. The examinations were performed by a radiologist with more than 20 years of experience in ultrasound. RESULTS: The predominant gender was female (in 88...
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28412700/takayasu-arteritis-and-spondyloarthritis-coincidence-or-association-a-study-of-14-cases
#16
Elodie Rivière, Laurent Arnaud, Mikael Ebbo, Yannick Allanore, Pascal Claudepierre, Emmanuelle Dernis, Jean-Marc Ziza, Corinne Miceli-Richard, Peggy Philippe, Christophe Richez, Martin Soubrier, Rakiba Belkhir, Raphaèle Seror, Xavier Mariette, Stephan Pavy
OBJECTIVE: Spondyloarthritis (SpA) and Takayasu arteritis (TA) are 2 chronic inflammatory diseases; their coexistence in a single patient is uncommon. The aims of our study were to describe clinical features of patients having SpA associated with TA and to identify some characteristics of the types of patients with SpA associated with TA. We also analyzed treatments used in this context. METHODS: This French multicenter retrospective survey called for observations on behalf of the Club Rhumatismes et Inflammations, with a standardized questionnaire established by the investigators...
April 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28407127/no-clear-association-between-ultrasound-remission-and-health-status-in-rheumatoid-arthritis-patients-in-clinical-remission
#17
Myrthe van der Ven, T Martijn Kuijper, Andreas H Gerards, Ilja Tchetverikov, Angelique E Weel, Jendé van Zeben, Johanna M Hazes, Jolanda J Luime
Objectives.: Although RA patients achieve clinical remission, risk of flare still exists. Given the association between US synovitis and increased risk of flare, it is of clinical interest whether these patients report a different health status. Therefore, our aim was to evaluate the frequency of US remission in RA patients in clinical remission and to compare the health status of RA patients in clinical remission with those who were also in US remission. Methods: ...
April 11, 2017: Rheumatology
https://www.readbyqxmd.com/read/28371912/hereditary-hemochromatosis-arthropathy-and-doppler-ultrasound-findings-of-synovitis
#18
Anu R Oke, Ernest Wong, Fiona McCrae, Steven Young-Min
No abstract text is available yet for this article.
March 22, 2017: Rheumatology
https://www.readbyqxmd.com/read/28343011/ultrasound-characterization-of-ankle-involvement-in-l%C3%A3-fgren-syndrome
#19
Claire Goussault, Jean-David Albert, Guillaume Coiffier, François Lamer, Raphaël Guillin, Benoit Le Goff, Béatrice Bouvard, Emmanuelle Dernis, Marine Ferreyra, Grégoire Cormier, Pascal Guggenbuhl, Aleth Perdriger
BACKGROUND: Bilateral ankle arthritis is a classic diagnostic criterion for Löfgren syndrome. The objective of this study was to use ultrasonography to characterize the articular and peri-articular involvement of the ankles in patients with Löfgren syndrome. METHODS: Single-center descriptive cohort study of patients with Löfgren syndrome who underwent ultrasonography of the ankles. We collected clinical data, imaging study findings, blood test results, and joint fluid properties in patients who underwent joint aspiration...
March 22, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28340066/diagnostic-test-accuracy-of-ultrasound-for-synovitis-in-rheumatoid-arthritis-systematic-review-and-meta-analysis
#20
Kaoru Takase-Minegishi, Nobuyuki Horita, Kouji Kobayashi, Ryusuke Yoshimi, Yohei Kirino, Shigeru Ohno, Takeshi Kaneko, Hideaki Nakajima, Richard J Wakefield, Paul Emery
Objective.: To evaluate diagnostic test accuracy of US compared with MRI for the detection of synovitis in RA patients. Methods.: A systematic literature search was performed in the PubMed, EMBASE, Cochrane Library and Web of Science Core Collection databases. Studies evaluating the diagnostic test accuracy of US for synovitis detected by MRI as the reference standard for wrist, MCP, PIP and knee joints were included. To assess the overall accuracy, we calculated the diagnostic odds ratio using a DerSimonian-Laird random effects model and the area under the curve (AUC) for the hierarchical summary receiver operating characteristics using Holling's proportional hazards models...
March 3, 2017: Rheumatology
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