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https://www.readbyqxmd.com/read/28630564/cathrob-a-highly-compact-and-versatile-remote-catheter-navigation-system
#1
Laura Cercenelli, Barbara Bortolani, Emanuela Marcelli
Several remote catheter navigation systems have been developed and are now commercially available. However, these systems typically require specialized catheters or equipment, as well as time-consuming operations for the system set-up. In this paper, we present CathROB, a highly compact and versatile robotic system for remote navigation of standard tip-steerable electrophysiology (EP) catheters. Key features of CathROB include an extremely compact design that minimizes encumbrance and time for system set-up in a standard cath lab, a force-sensing mechanism, an intuitive command interface, and functions for automatic catheter navigation and repositioning...
2017: Applied Bionics and Biomechanics
https://www.readbyqxmd.com/read/28629863/the-unfolding-mechanism-of-monomeric-mutant-sod1-by-simulated-force-spectroscopy
#2
Mona Habibi, Jörg Rottler, Steven S Plotkin
Mechanical unfolding of mutated apo, disulfide-reduced, monomeric superoxide dismutase 1 protein (SOD1) has been simulated via force spectroscopy techniques, using both an all-atom (AA), explicit solvent model and a coarse-grained heavy-atom Gō (HA-Gō) model. The HA-Gō model was implemented at two different pulling speeds for comparison. The most-common sequence of unfolding in the AA model agrees well with the most-common unfolding sequence of the HA-Gō model, when the same normalized pulling rate was used...
June 16, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28628800/increased-internal-femoral-torsion-can-be-regarded-as-a-risk-factor-for-patellar-instability-a-biomechanical-study
#3
Peter Kaiser, Werner Schmoelz, Philip Schoettle, Marit Zwierzina, Christian Heinrichs, Rene Attal
BACKGROUND: Increased internal femoral torsion is regarded as a risk factor for patellar instability. Biomechanical investigations confirming this hypothesis are missing. METHODS: Eight fresh-frozen cadaver knees were tested on a specially designed simulator. Patellar motion and patellofemoral pressure were evaluated for 0°, 10°, and 20° of increased internal and external femoral torsion with native and with transected medial patellofemoral ligaments used to simulate patellar instability...
June 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28628157/-biomechanical-analysis-of-the-deep-radioulnar-ligaments-stabilizing-the-distal-radioulnar-joint
#4
(no author information available yet)
OBJECTIVE: To evaluate the role of the deep radioulnar ligament in the stability of the distal radioulnar joint (DRUJ). METHODS: In the study, 14 fresh cadaver upper extremities were randomly divided into two groups. After exposuring the palmar and dorsal deep distal radioulnar ligament, one group was marked as palmar deep radioulnar ligament, and the other group was marked as dorsal deep radioulnar ligament. The pronator teres and the supinator were exposed. A Kirschner wire perpendicular to the bone on Lister tubercle of radius was inserted, then another Kirschner wire on the same level of ulnar inserted when the forearm was in neural position, which was kept parallel to the first Kirschner wire...
June 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28627119/australian-century
#5
EDITORIAL
Theresa Kueckmann, Roger Stapleford
Let the corks pop! This year, the Royal Australian Chemical Institute (RACI), a partner of the Asian Chemical Editorial Society (ACES) and co-owner of Chemistry - An Asian Journal, celebrates its 100th anniversary. This special issue honors that occasion. In the Editorial, Chemistry - An Asian Journal Editor Theresa Kueckmann and RACI CEO Roger Stapleford look at the connection between the journal, ACES and RACI and how RACI has become a driving force in connecting chemists among themselves and within Australian society...
June 19, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28622329/plastic-modification-of-the-cornea-by-pneumatic-force-corrects-myopia-pneumatic-keratology
#6
A Medina
PurposeThe eyeball and, in particular, the cornea deform in vitro by the application of a distending force like other visco-elastic tissue. If the force is large enough, the cornea strains beyond the elastic range, and a permanent deformation occurs. Such permanent strain is referred to as 'plastic' strain. The phenomenon, however, has never been observed or produced on living tissue. This report seeks to demonstrate that the central radius of a patient's cornea can be altered in a controlled manner designed to correct refractive errors...
June 16, 2017: Eye
https://www.readbyqxmd.com/read/28620932/fiber-type-composition-of-the-palmaris-brevis-muscle-implications-for-palmar-function
#7
Colin W Moore, Tyler S Beveridge, Charles L Rice
The palmaris brevis (PB) is a small muscle of variant morphology located on the ulnar aspect of the palm, superficial to the hypothenar eminence. Functionally, the PB has been proposed to protect the neurovasculature of the ulnar canal from compressive forces during repetitive or intermittent trauma associated with grasping. Although PB function has been inferred from cadaveric observations, it is unknown whether it has the contractile capacity and fatigue-resistance necessary to withstand these functional demands...
June 16, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28618331/psychogenic-nonepileptic-seizures-namibian-healthcare-providers-perceptions-and-frustrations
#8
Anina du, Toit, Chrisma Pretorius
PURPOSE: Most studies conducted on the diagnosis and treatment of psychogenic nonepileptic seizures (PNES) have been performed in developed countries with developing countries, such as Namibia, receiving less attention. This study aimed to contribute to the aims of The International League against Epilepsy Psychogenic Nonepileptic Seizure Task Force by investigating the perceptions and frustrations of healthcare providers (HCPs) in Namibia regarding the diagnosis and treatment of psychogenic nonepileptic seizures...
June 9, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28616624/fatigue-crack-closure-a-review-of-the-physical-phenomena
#9
REVIEW
R Pippan, A Hohenwarter
Plasticity-induced, roughness-induced and oxide-induced crack closures are reviewed. Special attention is devoted to the physical origin, the consequences for the experimental determination and the prediction of the effective crack driving force for fatigue crack propagation. Plasticity-induced crack closure under plane stress and plane strain conditions require, in principle, a different explanation; however, both types are predictable. This is even the case in the transition region from the plane strain to the plane stress state and all types of loading conditions including constant and variable amplitude loading, the short crack case or the transition from small-scale to large-scale yielding...
April 2017: Fatigue Fract Eng Mater Struct
https://www.readbyqxmd.com/read/28616418/researcher-s-experiences-about-their-publication-in-isi-journals-a-qualitative-study-in-isfahan-university-of-medical-sciences
#10
Rasool Nouri, Mahmoud Keyvanara, Rezvan Ojaghi, Anasic Lalazarian, Urfa Hovsepian
BACKGROUND: As one of the indicators of actual growth and scientific development capacity of countries, the importance of the research is steadily increasing. Knowing that success depends on the work done by researchers so identified identify these barriers and pave the way for one of the concerned authorities of their research. METHODS: This qualitative study using analysis of the theme. Semi-structured interviews were used to collect the data. Participants include people who are experienced and knowledgeable in the field...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/28601206/prolonged-field-care-beyond-the-golden-hour
#11
REVIEW
Sean Keenan, Jamie C Riesberg
Prolonged field care (PFC) has emerged as a recent area of focus for US military Special Operations Forces (SOF) medical experts. Focused on the current reality of providing medical care to military forces often deployed in remote and austere locations far from medical support or a robust casualty evacuation chain, PFC encompasses evolving operational situations not unlike many wilderness medicine practice environments. SOF currently operates in all areas of the world and on a variety of different missions, which finds these small teams far from the accustomed practice environment of robust deployed medical infrastructure commonly seen during the last 15 years of military conflicts...
June 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28600826/tinker-openmm-absolute-and-relative-alchemical-free-energies-using-amoeba-on-gpus
#12
Matthew Harger, Daniel Li, Zhi Wang, Kevin Dalby, Louis Lagardère, Jean-Philip Piquemal, Jay Ponder, Pengyu Ren
The capabilities of the polarizable force fields for alchemical free energy calculations have been limited by the high computational cost and complexity of the underlying potential energy functions. In this work, we present a GPU-based general alchemical free energy simulation platform for polarizable potential AMOEBA. Tinker-OpenMM, the OpenMM implementation of the AMOEBA simulation engine has been modified to enable both absolute and relative alchemical simulations on GPUs, which leads to a ∼200-fold improvement in simulation speed over a single CPU core...
June 10, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/28599568/relationship-of-scattering-phase-shifts-to-special-radiation-force-conditions-for-spheres-in-axisymmetric-wave-fields
#13
Philip L Marston, Likun Zhang
When investigating the radiation forces on spheres in complicated wave-fields, the interpretation of analytical results can be simplified by retaining the s-function notation and associated phase shifts imported into acoustics from quantum scattering theory. For situations in which dissipation is negligible, as taken to be the case in the present investigation, there is an additional simplification in that partial-wave phase shifts become real numbers that vanish when the partial-wave index becomes large and when the wave-number-sphere-radius product vanishes...
May 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28599043/ketones-and-human-performance
#14
Jonathan M Scott, Patricia A Deuster
Everyone is seeking nutritional strategies that might benefit performance. One approach receiving much attention is ketones, or ketosis. Ketones are very simple compounds made of hydrogen, carbon, and oxygen, and ketosis is a metabolic state whereby the body uses predominantly ketones. Ketosis can be achieved by fasting for longer than 72 hours or by following a very lowcarbohydrate, high-fat diet (ketogenic diet) for several days to weeks. Alternatively, ketone supplements purportedly induce ketosis rapidly and do not require strict adherence to any specific type of diet; however, much of the touted benefits are anecdotal...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28599037/the-sole-provider-preparation-for-deployment-to-a-medically-austere-theater
#15
Paul Corso, Cristobal Mandry, Steven Reynolds
The combat focus of the US Military over the past 15 years has primarily centered on the Iraq and Afghanistan areas of operation (AOs). Thus, much human and financial capital has been dedicated to the creation of a robust medical infrastructure to support those operations. However, Special Operation Forces (SOF) are often called upon to deploy in much more medically austere AOs. SOF medical providers operating in such environments face significant challenges due to the diversity of medical threats, extremely limited access to medical resupply, a material shortage of casualty evacuation platforms, lack of medical facilities, and limited access to higher-level care providers...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28599035/rapid-vision-correction-by-special-operations-forces
#16
Mark E Reynolds
BACKGROUND: This report describes a rapid method of vision correction used by Special Operations Medics in multiple operational engagements. METHODS: Between 2011 and 2015, Special Operations Medics used an algorithm- driven refraction technique. A standard block of instruction was provided to the medics, along with a packaged kit. The technique was used in multiple operational engagements with host nation military and civilians. Data collected for program evaluation were later analyzed to assess the utility of the technique...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28599031/foreign-language-short-course-special-operations-clinical-research-fundamentals
#17
Kate Rocklein Kemplin, F Bowling
When we do not know a language, we are at the mercy of an interpreter. The same is true for research: Special Operations Forces (SOF) clinicians not actively involved in research initiatives may rely on scientific interpreters, so it is important to speak some of the language personally. For any clinician, using evidence in practice requires a working knowledge of how that evidence was generated from research, which requires an understanding of research science language. Here we review common basics of research science to reinforce concepts and elements of experimental and nonexperimental research...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28597591/morphological-variation-in-anuran-limbs-constraints-and-novelties
#18
Marissa Fabrezi, Javier Goldberg, Mariana Chuliver Pereyra
Anurans have three primary types of locomotion: walking, jumping, and swimming. Additionally, they may dig, climb, grasp, etc. All adult anurans have four limbs, with four fingers on the hands and five toes on the feet. We summarized and updated knowledge on the interspecific variation within anuran limbs, then discuss how developmental constraints (e.g., in size) and novelties may have influenced anuran diversification through the locomotion. We analyze morphological variation from limb bud stages up to the final limb form resulting from certain skeletal organization and growth...
June 9, 2017: Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
https://www.readbyqxmd.com/read/28594520/pediatric-metacarpal-fractures
#19
Jenna Godfrey, Roger Cornwall
Metacarpal fractures account for 10% to 35% of all pediatric hand fractures. Pediatric metacarpal fractures commonly occur in patients aged 13 to 16 years, with most injuries sustained during sports activities. Pseudoepiphyses can be confused with metacarpal fractures; however, a careful physical examination can help physicians distinguish the two. Thumb metacarpal base fractures that involve the physis warrant special attention. Thumb metacarpal base fractures with lateral metaphyseal fragments and pediatric Bennett fracture variants (Salter-Harris type III and type IV fractures) are unstable and require surgical management...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28589380/persistence-with-denosumab-therapy-in-women-affected-by-osteoporosis-with-fragility-fractures-a-multicenter-observational-real-practice-study-in-italy
#20
S Migliaccio, D Francomano, E Romagnoli, C Marocco, R Fornari, G Resmini, A Buffa, G Di Pietro, S Corvaglia, F Gimigliano, A Moretti, A de Sire, N Malavolta, A Lenzi, E A Greco, G Iolascon
BACKGROUND: Persistence is commonly considered a key factor for the successful management of osteoporosis and fragility fractures. Denosumab is the first biologic agent developed for the treatment of osteoporosis with satisfying data regarding the persistence with this therapy. AIM: The purpose of this multicenter observational real practice study was to evaluate the persistence with denosumab treatment in post-menopausal women affected by osteoporosis. MATERIAL/SUBJECTS AND METHODS: Women were recruited in four specialized centers for the management of osteoporosis in North, Center and South of Italy...
June 6, 2017: Journal of Endocrinological Investigation
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