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https://www.readbyqxmd.com/read/28814013/a-third-arm-design-of-a-bypass-prosthesis-enabling-incorporation
#1
Adam W Wilson, Daniel H Blustein, Jon W Sensinger
A variety of factors affect the performance of a person using a myoelectric prosthesis, including increased control noise, reduced sensory feedback, and muscle fatigue. Many studies use able-bodied subjects to control a myoelectric prosthesis using a bypass socket in order to make comparisons to movements made with intact limbs. Depending on the goals of the study, this approach can also allow for greater subject numbers and more statistical power in the analysis of the results. As we develop assessment tools and techniques to evaluate how peripheral nerve interfaces impact prosthesis incorporation, involving normally limbed subjects in the studies becomes challenging...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813820/design-of-an-exoskeleton-ankle-robot-for-robot-assisted-gait-training-of-stroke-patients
#2
Ling-Fung Yeung, Corinna Ockenfeld, Man-Kit Pang, Hon-Wah Wai, Oi-Yan Soo, Sheung-Wai Li, Kai-Yu Tong
Lower Limb Exoskeleton robot that can facilitate stair walking is a big challenge, most systems could only provide level ground walking. In this study, a lightweight (0.5kg at ankle, 0.5kg at waist for control box) and autonomous exoskeleton Ankle Robot was proposed to provide power assistance for gait training of chronic stroke patients and it can facilitate three walking conditions in real-time: (1) level walking, (2) stair ascending, and (3) stair descending. Chronic stroke patients (n=3) with drop foot gait deficit and moderate motor impairment were recruited to evaluate the system under different walking conditions (Functional Ambulatory Category: FAC=4...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813799/toward-emg-controlled-force-field-generation-for-training-and-rehabilitation-from-movement-data-to-muscle-geometry
#3
Nicola Lotti, Vittorio Sanguinati
EMG signals are often used to control prostheses or assistive devices, but have been rarely used in rehabilitation. We propose a novel approach to personalised rehabilitation, based on EMG-driven force field adaptation. As a step toward this direction, here we show how EMG activity and movement data during a robot-assisted motor task can be used to estimate muscle geometry. We compare three different models of muscle geometry, characterised by (i) constant moment arms (CM); (ii) a normative model, based on polynomial functions of joint angles with fixed coefficients (normative polynomial, NP); and (iii) a person-adaptive model, in which the same polynomial model is fitted to individual subjects data (fitted polynomial, FP)...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28811262/probe-microscopy-methods-and-applications-in-imaging-of-biological-materials
#4
REVIEW
Alper D Ozkan, Ahmet E Topal, Fatma B Dikecoglu, Mustafa O Guler, Aykutlu Dana, Ayse B Tekinay
Atomic force microscopy is an emerging tool for investigating the biomolecular aspects of cellular interactions; however, cell and tissue analyses must frequently be performed in aqueous environment, over rough surfaces, and on complex adhesive samples that complicate the imaging process and readily facilitate the blunting or fouling of the AFM probe. In addition, the shape and surface chemistry of the probe determine the quality and types of data that can be acquired from biological materials, with certain information becoming available only within a specific range of tip lengths or diameters, or through the assistance of specific chemical or biological functionalization procedures...
August 12, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28809848/a-multimodal-dataset-for-various-forms-of-distracted-driving
#5
Salah Taamneh, Panagiotis Tsiamyrtzis, Malcolm Dcosta, Pradeep Buddharaju, Ashik Khatri, Michael Manser, Thomas Ferris, Robert Wunderlich, Ioannis Pavlidis
We describe a multimodal dataset acquired in a controlled experiment on a driving simulator. The set includes data for n=68 volunteers that drove the same highway under four different conditions: No distraction, cognitive distraction, emotional distraction, and sensorimotor distraction. The experiment closed with a special driving session, where all subjects experienced a startle stimulus in the form of unintended acceleration-half of them under a mixed distraction, and the other half in the absence of a distraction...
August 15, 2017: Scientific Data
https://www.readbyqxmd.com/read/28808455/effect-of-nickel-chromium-and-non-precious-gold-color-alloy-cast-posts-on-fracture-resistance-of-endodontically-treated-teeth
#6
Fatemeh Gholami, Parisa Kohani, Shima Aalaei
INTRODUCTION: Root canal-treated teeth are weaker than vital teeth and are more susceptible to fractures. Therefore, special precautions should be adhered to, such as the use of various types of cast or prefabricated posts. Regarding the effect of post material on fracture resistance of teeth, the aim of this in vitro study was to evaluate the effect of non-precious gold color alloy (NPG) and nickel-chrome (Ni-Cr) cast posts on resistance of endodontically treated teeth. METHODS AND MATERIALS: In this study, 30 freshly extracted single-rooted premolar teeth were randomly divided into two groups...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28804812/predominance-of-comorbidities-in-the-detriment-of-daily-activity-in-sarcoidosis-patients
#7
S Kostorz, D Jastrzębski, M Sikora, A Zebrowska, A Margas, D Stepanik, H Swinder, D Ziora
Sarcoidosis may affect lung function, working ability, overall mobility, and daily activity. In the present study we performed an analysis of clinical settings in patients with sarcoidosis to disentangle its influence on daily physical activity (PA). PA assessment (number of steps per day, daily energy expenditure) was performed by accelerometry during consecutive 7 days after discharge from hospital. Thirty patients with sarcoidosis, aged 46.4 ± 10.5, were enrolled in the study. Clinical data (age, gender, steroid consumption, weight, and comorbidities), lung function tests (forced expiratory volume in one second - FEV1, forced vital capacity - FVC, and lung diffusion for carbon monoxide - DLCO), mobility (6-minute walk test- 6MWT) and physical performance (oxygen consumption at anaerobic threshold - VO2/AT) were estimated...
August 15, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28803215/structural-tribological-and-mechanical-properties-of-the-hind-leg-joint-of-a-jumping-insect-using-katydids-to-inform-bioinspired-lubrication-systems
#8
Jun Kyun Oh, Spencer T Behmer, Richelle Marquess, Cengiz Yegin, Ethan A Scholar, Mustafa Akbulut
This study investigates the structural properties of the hind leg femur-tibia joint in adult katydids (Orthoptera: Tettigoniidae), including its tribological and mechanical properties. It is of particular interest because the orthopteran (e.g., grasshoppers, crickets, and katydids) hind leg is highly specialized for jumping. We show that the katydid hind leg femur-tibia joint had unique surfaces and textures, with a friction coefficient (μ) at its coupling surface of 0.053 ± 0.001. Importantly, the sheared surfaces at this joint showed no sign of wear or damage, even though it had undergone thousands of external shearing cycles...
August 9, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28802627/sensorless-control-for-switched-reluctance-motor-based-on-special-position-detection
#9
Jie Shao, Zhiquan Deng, Yu Gu
This paper proposes a new sensorless control approach for switched reluctance motor (SRM) in the single pulse control mode in high speed operation. The sensorless method uses the cross point position of transformer electromotive force (EMF) and motional back electromotive force (BEMF) to estimate the rotor position. The cross point position can be derived from the inductance model of SRM, and it is regarded as reference position. The rotor position can be calculated by detecting the special position for each electrical cycle...
August 9, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28799391/vapor-bridges-between-solid-substrates-in-the-presence-of-the-contact-line-pinning-effect-stability-and-capillary-force
#10
Yawei Liu, Xianren Zhang
In this work, we focus on investigating how nanobubbles mediate long-range interaction between neighboring solid substrates in the presence of the contact line pinning effect caused by surface heterogeneities. Using the constrained lattice density functional theory (LDFT), we prove that the nanobubbles, which take the form of vapor bridges here, are stabilized by the pinning effect if the separation between two substrates is less than a critical distance. The critical distance strongly depends on the chemical potential (i...
December 7, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28797848/development-of-palliative-care-pc-in-armenia
#11
Anahit Papikyan, Stephen R Connor, Davit Amiryan
In the last seven years, considerable progress has been made in palliative care in Armenia but many problems remain unresolved. Policies developed include completion of a national needs assessment, a recognized working group on palliative care formed, national standards approved, a concept paper on palliative care approved, resolutions on palliative care as a specialized service approved, palliative care became a subspecialty in medicine, palliative care qualifications developed, and a social assistance package approved...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28796323/focal-adhesions-a-personal-perspective-on-a-half-century-of-progress
#12
REVIEW
Keith Burridge
Focal adhesions are specialized sites within the cell where clustered integrin receptors interact with the extracellular matrix on the outside of cells and with the actin cytoskeleton on the inside. They provide strong adhesion to the matrix and transmit mechanical tension generated within cells across the plasma membrane to the external environment. Additionally, they act as scaffolds for many signaling pathways triggered by integrin engagement or mechanical force exerted on cells. Here I describe my personal perspective on focal adhesion research which I have witnessed since the initial discovery and description of focal adhesions as electron dense regions of the ventral plasma nearly half a century ago...
August 10, 2017: FEBS Journal
https://www.readbyqxmd.com/read/28795004/the-female-athlete-triad-special-considerations-for-adolescent-female-athletes
#13
REVIEW
Kelly A Brown, Aditya V Dewoolkar, Nicole Baker, Colleen Dodich
The number of adolescent girls participating in sports has dramatically increased throughout the last few decades. In the early 1990's, an association between amenorrhea, osteoporosis, and disordered eating was recognized and eventually labeled the 'Female Athlete Triad'. In 1997, the Task Force on Women's Issues of American College of Sports Medicine (ACSM) published a position statement on this triad of conditions that were becoming increasingly more prevalent amongst female athletes. Initially, the 'Female Athlete Triad' was characterized by disordered eating, amenorrhea, and osteoporosis...
July 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28793207/divalent-ion-mediated-dna-dna-interactions-a%C3%A2-comparative-study-of-triplex-and-duplex
#14
Zhong-Liang Zhang, Yuan-Yan Wu, Kun Xi, Jian-Ping Sang, Zhi-Jie Tan
Ion-mediated interaction between DNAs is essential for DNA condensation, and it is generally believed that monovalent and nonspecifically binding divalent cations cannot induce the aggregation of double-stranded (ds) DNAs. Interestingly, recent experiments found that alkaline earth metal ions such as Mg(2+) can induce the aggregation of triple-stranded (ts) DNAs, although there is still a lack of deep understanding of the surprising findings at the microscopic level. In this work, we employed all-atom dynamic simulations to directly calculate the potentials of mean force (PMFs) between tsDNAs, between dsDNAs, and between tsDNA and dsDNA in Mg(2+) solutions...
August 8, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28791820/evaluation-of-articular-disc-loading-in-the-temporomandibular-joints-after-prosthetic-and-pharmacological-treatment-in-model-studies
#15
Małgorzata E Pihut, Jerzy Margielewicz, Edward Kijak, Grażyna Wiśniewska
BACKGROUND: Temporomandibular joint dysfunction is often related to excessive load in the stomatognathic system. OBJECTIVES: The objective of the model tests, using numeric calculations, was to assess the articular disc loads in the temporomandibular joints after prosthetic and pharmacological treatment of functional disorders of the masticatory organ. MATERIAL AND METHODS: The study involved 10 patients, aged 21-48 years, of both sexes, randomly selected from a group of 120 patients treated with relaxation occlusal splints (60 patients, group I) and intramuscular injection of botulinum toxin type A (60 patients, group II), suffering from temporomandibular joint dysfunction with the dominant muscle component...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28791459/three-year-lifecycle-large-body-and-very-high-threshold-temperature-in-the-cricket-gryllus-argenteus-for-special-adaptation-to-desiccation-cycle-in-malawi
#16
Takuya Kosumi, Makio Takeda
In temperate climates, the initiation and termination of diapause synchronize the stress-tolerant stage with the stressful season and reproduction with the non-stressful season in many insects. Synchronization is often regulated by photoperiodism.Voltinism and the ultimate size of adults are also important determinants for their lifecycle, and different diapause stages and voltinism patterns are known in crickets.Here, we investigated the life history of the African cricket Gryllus argenteus from Malawi, which is a typical arid tropical highland...
August 8, 2017: Die Naturwissenschaften
https://www.readbyqxmd.com/read/28790955/oxygen-toxicity-and-special-operations-forces-diving-hidden-and-dangerous
#17
REVIEW
Thijs T Wingelaar, Pieter-Jan A M van Ooij, Rob A van Hulst
In Special Operations Forces (SOF) closed-circuit rebreathers with 100% oxygen are commonly utilized for covert diving operations. Exposure to high partial pressures of oxygen (PO2) could cause damage to the central nervous system (CNS) and pulmonary system. Longer exposure time and higher PO2 leads to faster development of more serious pathology. Exposure to a PO2 above 1.4 ATA can cause CNS toxicity, leading to a wide range of neurologic complaints including convulsions. Pulmonary oxygen toxicity develops over time when exposed to a PO2 above 0...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28790313/evolution-of-new-regulatory-functions-on-biophysically-realistic-fitness-landscapes
#18
Tamar Friedlander, Roshan Prizak, Nicholas H Barton, Gašper Tkačik
Gene expression is controlled by networks of regulatory proteins that interact specifically with external signals and DNA regulatory sequences. These interactions force the network components to co-evolve so as to continually maintain function. Yet, existing models of evolution mostly focus on isolated genetic elements. In contrast, we study the essential process by which regulatory networks grow: the duplication and subsequent specialization of network components. We synthesize a biophysical model of molecular interactions with the evolutionary framework to find the conditions and pathways by which new regulatory functions emerge...
August 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28790201/division-of-labor-bet-hedging-and-the-evolution-of-mixed-biofilm-investment-strategies
#19
Nick Vallespir Lowery, Luke McNally, William C Ratcliff, Sam P Brown
Bacterial cells, like many other organisms, face a tradeoff between longevity and fecundity. Planktonic cells are fast growing and fragile, while biofilm cells are often slower growing but stress resistant. Here we ask why bacterial lineages invest simultaneously in both fast- and slow-growing types. We develop a population dynamic model of lineage expansion across a patchy environment and find that mixed investment is favored across a broad range of environmental conditions, even when transmission is entirely via biofilm cells...
August 8, 2017: MBio
https://www.readbyqxmd.com/read/28789884/single-molecule-imaging-and-manipulation-of-biomolecular-machines-and-systems
#20
REVIEW
Ryota Iino, Tatsuya Iida, Akihiko Nakamura, Ei-Ichiro Saita, Huijuan You, Yasushi Sako
Biological molecular machines support various activities and behaviors of cells, such as energy production, signal transduction, growth, differentiation, and migration. Scope of Review We provide an overview of single-molecule imaging methods involving both small and large probes used to monitor the dynamic motions of molecular machines in vitro (purified proteins) and in living cells, and single-molecule manipulation methods used to measure the forces, mechanical properties and responses of biomolecules. We also introduce several examples of single-molecule analysis, focusing primarily on motor proteins and signal transduction systems...
August 5, 2017: Biochimica et Biophysica Acta
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