Kevin G Friedman, Renee Margossian, Dionne A Graham, David M Harrild, Sitaram M Emani, Louise E Wilkins-Haug, Doff B McElhinney, Wayne Tworetzky
Fetal aortic balloon valvuloplasty (FAV) has shown promise in altering in utero progression of aortic stenosis to hypoplastic left heart syndrome. In patients who achieve a biventricular circulation after FAV, left ventricular (LV) compliance may be impaired. Echocardiographic indexes of diastolic function were compared between patients with biventricular circulation after FAV, congenital aortic stenosis (AS), and age-matched controls. In the neonatal period, patients with FAV had similar LV, aortic, and mitral valve dimensions but more evidence of endocardial fibroelastosis than patients with AS...
August 15, 2011: American Journal of Cardiology