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Laryngotracheal stenosis

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https://www.readbyqxmd.com/read/27861938/voice-outcome-and-voice-related-quality-of-life-after-surgery-for-pediatric-laryngotracheal-stenosis
#1
Bas Pullens, Marieke Hakkesteegt, Hans Hoeve, Marieke Timmerman, Koen Joosten
OBJECTIVES: To evaluate the long-term outcome of voice quality and voice-related quality of life after open airway surgery for pediatric laryngotracheal stenosis. STUDY DESIGN: Prospective cohort study. METHODS: Children under the age of 18 years at time of follow-up and with a history of open airway surgery for acquired laryngotracheal stenosis were included in this analysis. To assess voice-related quality of life, the pediatric voice handicap (pVHI) index was completed by the patients' parents...
November 9, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27861923/evaluating-the-utility-of-serological-testing-in-laryngotracheal-stenosis
#2
S Ryan Hall, Clint T Allen, Albert L Merati, Ross M Mayerhoff
OBJECTIVES/HYPOTHESIS: Whereas mechanical (traumatic) causes of laryngotracheal stenosis (LTS) are identified based on history, autoimmune laryngotracheal stenosis (aLTS) and idiopathic laryngotracheal stenosis (iLTS) are often more difficult to differentiate. The objective of this study was to evaluate serologic testing in a large cohort of nonmechanical LTS patients to determine which tests, if any, lead clinicians to the etiology of the LTS. STUDY DESIGN: Retrospective chart review...
November 12, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27833870/use-of-conchal-cartilages-for-laryngotracheal-stenosis-experiences-at-a-tertiary-care-hospital-of-eastern-india
#3
Santosh Kumar Swain, Neha Singh, Rankanidhi Samal, Santosh Kumar Pani, Mahesh Chandra Sahu
To describe the experience of anterior cricotracheal split with insertion of conchal cartilage graft in the treatment of subglottic and tracheal stenosis at a tertiary care hospital of eastern India. Six patients were included in the study, in the age group of 20-48 years. Out of which five patients were successfully decannulated after 3 months of laryngotracheal reconstruction with help of conchal cartilage. One case was undergone resection anastomosis after failure of the above technique. Successful restoration of the airway with decannulation in five cases and failure in one case...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27774924/tracheal-t-tube-a-novel-endoscopic-insertion-technique
#4
A Nor Rahimah, F I Shahfi, M Masaany, N Gazali, S H Siti
BACKGROUND: Laryngotracheal stenosis is a complex condition of airway compromise involving either the larynx or trachea, or both. OBJECTIVES: This paper describes a new method of endoscopically inserting a silicone tracheal T-tube as treatment for laryngotracheal stenosis. The advantages of this method over previously described methods are discussed.
October 2016: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/27772613/a-novel-technique-for-laryngotracheal-reconstruction-for-idiopathic-subglottic-stenosis
#5
Anna M Ciccone, Camilla Vanni, Giulio Maurizi, Antonio D'Andrilli, Stylianos Korasidis, Mohsen Ibrahim, Claudio Andreetti, Federico Venuta, Erino A Rendina
Idiopathic subglottic stenosis is the most challenging condition in the field of upper airway reconstruction. We describe a successful novel technique for enlarging the airway space at the site of the laryngotracheal anastomosis in very high-level reconstructions.
November 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27768157/initial-experience-with-low-dose-methotrexate-as-an-adjuvant-treatment-for-rapidly-recurrent-nonvasculitic-laryngotracheal-stenosis
#6
David E Rosow, Jamal Ahmed
Importance: Adult laryngotracheal stenosis (LTS) is typically managed surgically, but some patients fail treatment because of rapid restenosis or granulation tissue formation. The need for frequent surgery or tracheostomy reduces the quality of life in these patients and poses a significant challenge for the treating physician. New adjuvant treatments are required to reduce the surgical burden of this condition. Objective: To examine whether patients with rapidly recurrent nonvasculitic LTS who fail surgical management of their stenosis (ie, requiring dilation more frequently than every 6 months) experience longer intervals between surgical procedures when receiving adjuvant treatment with low-dose methotrexate...
October 20, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27767216/systematic-review-for-surgical-treatment-of-adult-and-adolescent-laryngotracheal-stenosis
#7
Sean Lewis, Marisa Earley, Richard Rosenfeld, Joshua Silverman
OBJECTIVES/HYPOTHESIS: To determine if open surgical treatment options for adult and adolescent laryngotracheal stenosis are more successful than endoscopic procedures. STUDY DESIGN: Systematic review. METHODS: Embase and MEDLINE were searched for publications on adult and adolescent patients (>13 years old) with laryngotracheal stenosis. Cause of stenosis (intubation, idiopathic, or trauma) and treatments (open laryngotracheal resection with anastomosis, open laryngotracheal reconstruction with expansion grafting, or endoscopic procedures) were included...
October 21, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27694536/laryngotracheal-stenosis-in-children-and-infants-with-neurological-disorders-management-and-outcome
#8
Richard Nicollas, Eric Moreddu, Claire Le Treut-Gay, Stéphane Roman, Julien Mancini, Jean-Michel Triglia
INTRODUCTION: The goal of this retrospective study is to compare the management and outcome of surgical treatment of laryngotracheal stenosis in children and infants with and without an associated neurological disorder. PATIENTS AND METHOD: In a series of children operated on for subglottic stenosis (SGS), patients with an associated neurological disorder were identified. The following criteria were compared in children with and without neurological disease: grade of stenosis, age, technique (Crico-Tracheal Resection (CTR), Laryngo-Tracheo-Plasty (LTP) in single and 2 stage, laser), analyzing duration, preoperative tracheostomy, decannulation rate, preoperative gastrostomy, and number of days in intensive care unit and in hospital...
December 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27641295/a-modified-technique-of-laryngotracheal-reconstruction-without-the-need-for-prolonged-postoperative-stenting
#9
Konrad Hoetzenecker, Thomas Schweiger, Imme Roesner, Matthias Leonhard, Gabriel Marta, Doris M Denk-Linnert, Berit Schneider-Stickler, Wolfgang Bigenzahn, Walter Klepetko
OBJECTIVES: Repair of laryngotracheal stenosis with pronounced side-to-side narrowing and involvement of the glottis is challenging and usually requires laryngotracheal reconstruction with rib cartilage interpositions. This technique, as first described by Couraud, needs prolonged postoperative stabilization with Montgomery T-tubes, imposing significant morbidity and discomfort on patients. We describe our initial experience with a modified laryngotracheal reconstruction technique that avoids the need for prolonged postoperative stenting...
October 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27589983/the-use-of-a-sternothyroid-muscle-flap-to-prevent-the-re-recurrence-of-a-recurrent-tracheoesophageal-fistula-found-10%C3%A2-years-after-the-primary-repair
#10
Hajime Takayasu, Kouji Masumoto, Miki Ishikawa, Takato Sasaki, Kentaro Ono
Recurrent tracheoesophageal fistula (TEF) is still difficult to diagnose and repair. In almost all cases, recurrence appears relatively soon after the primary surgery. We herein describe a case of recurrent TEF that appeared 10 years after the primary repair. At 2 years of age, the patient suffered from mental retardation due to encephalitis and developed a hiatus hernia with gastro-esophageal reflux. He underwent the repair of a hiatus hernia and fundoplication at 3 years of age. However, the hiatus hernia recurred 6 months after the operation...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27585358/metabolic-variations-in-normal-and-fibrotic-human-laryngotracheal-derived-fibroblasts-a-warburg-like-effect
#11
Garret Ma, Idris Samad, Kevin Motz, Linda X Yin, Madhavi V Duvvuri, Dacheng Ding, Daryan R Namba, Jennifer H Elisseeff, Maureen R Horton, Alexander T Hillel
OBJECTIVES/HYPOTHESIS: Laryngotracheal stenosis (LTS) is a chronic fibrotic disease characterized by fibroblast proliferation, collagen deposition, and matrix remodeling in the lamina propria of the larynx and/or trachea. Current medical therapies are limited by a poor understanding of the effector cell's (fibroblasts) cellular biology and metabolism. The purpose of this study was to compare cellular proliferation, function, and metabolism between normal and LTS-derived fibroblasts in vitro...
September 1, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27585080/review-of-adult-laryngotracheal-stenosis-pathogenesis-management-and-outcomes
#12
David E Rosow, Eric Barbarite
PURPOSE OF REVIEW: Adult laryngotracheal stenosis (LTS) is a potentially life-threatening disorder that can be difficult to diagnose and treat. Much is unknown regarding the etiology of airway stenosis, and while many patients do well with standard surgical management, the recurrence rate is significant. Few medical therapies exist, but there is a growing need. RECENT FINDINGS: Several basic science studies have shown a role of inflammatory signaling pathways in the development of LTS...
December 2016: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/27562837/natural-history-and-life-threatening-complications-in-myhre-syndrome-and-review-of-the-literature
#13
Livia Garavelli, Ilenia Maini, Federica Baccilieri, Ivan Ivanovski, Marzia Pollazzon, Simonetta Rosato, Lorenzo Iughetti, Sheila Unger, Andrea Superti-Furga, Marco Tartaglia
UNLABELLED: Myhre syndrome (OMIM 139210) is a rare developmental disorder inherited as an autosomal dominant trait and caused by a narrow spectrum of missense mutations in the SMAD4 gene. The condition features characteristic face, short stature, skeletal anomalies, muscle pseudohypertrophy, restricted joint mobility, stiff and thick skin, and variable intellectual disability. While most of the clinical features manifest during childhood, the diagnosis may be challenging during the first years of life...
October 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27542317/validation-of-the-airway-dyspnoea-voice-swallow-advs-scale-and-patient-reported-outcome-measure-prom-as-disease-specific-instruments-in-paediatric-laryngotracheal-stenosis
#14
S A R Nouraei, E Mucmur, A Dias, C R Butler, R Nandi, M J Eliott, R Hewitt
OBJECTIVE: To validate the airway-dyspnoea-voice-swallow (ADVS) instrument as a disease-specific patient-reported outcome measure in paediatric laryngotracheal stenosis. DESIGN: Prospective observational study. SETTING: A quaternary referral centre for complex airway disease. PARTICIPANTS: Forty eight patients (30 males) with a means age of 49±49 months who underwent laryngotracheal surgery or microlaryngosocpy and bronchoscopy (MLB) following laryngotracheal surgery...
August 20, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27533026/evaluation-of-dyspnea-outcomes-after-endoscopic-airway-surgery-for-laryngotracheal-stenosis
#15
Idris Samad, Lee Akst, Selmin Karatayli-Özgürsoy, Kristine Teets, Marissa Simpson, Ashwyn Sharma, Simon R A Best, Alexander T Hillel
Importance: Endoscopic airway surgery is a frequently used procedure in the management of laryngotracheal stenosis (LTS); however, no established outcome measures are available to assess treatment response. Objective: To assess acoustics and aerodynamic measures and voice- and dyspnea-related quality of life (QOL) in adult patients with LTS who undergo endoscopic airway surgery. Design, Setting, and Participants: This case series compared preoperative measures and postoperative outcomes among adult patients who underwent endoscopic airway surgery for LTS from September 1, 2013, to September 30, 2015, at the tertiary care Johns Hopkins Voice Center...
November 1, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27497417/extended-cricotracheal-resection-with-posterior-costochondral-grafting-for-complex-pediatric-subglottic-stenosis
#16
Jaime Penchyna Grub, Enrique Ortíz Hernández, Gustavo Teyssier Morales, Ivan Rivas Rivera, Diego Preciado, Hiram Álvarez-Neri
BACKGROUND AND OBJECTIVE: Severe laryngotracheal stenosis in childhood poses a complex surgical challenge for specialists in airway surgery. Patients with severe subglottic stenosis with vocal cord involvement are particularly difficult to manage successfully. The goal of this work was to review our experience with extended CTR in a cohort of young children with severe SGS and determine which clinical parameters would be associated with surgical success. METHODS: Retrospective analysis of the outcome of consecutive patients with severe glottic-subglottic stenosis submitted to an extended double-stage CTR between 2004 and 2014 at a large tertiary referral center...
September 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27329192/surgical-management-of-benign-acquired-tracheoesophageal-fistulas-a-ten-year-experience
#17
Benoit Jacques Bibas, Paulo Francisco Guerreiro Cardoso, Helio Minamoto, Leandro Picheth Eloy-Pereira, Mauro Federico L Tamagno, Ricardo Mingarini Terra, Paulo Manoel Pêgo-Fernandes
BACKGROUND: Benign tracheoesophageal fistulas (TEFs) are rare, and surgical correction is the ideal method of treatment. The objective of this study was to evaluate the results of operative treatment of benign TEFs in patients from a tertiary referral center. METHODS: Retrospective study of patients with benign TEFs who were treated between January 2005 and December 2014. Preoperative evaluation included computed tomography of the chest, bronchoscopy, and upper endoscopy...
October 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27280104/autologous-cricoid-cartilage-as-a-graft-for-airway-reconstruction-in-an-emergent-technique-a-case-report
#18
Farzad Izadi, Reza Vaghardoost, Vita Derakhshandeh, Behnam Sobouti, Yaser Ghavami
INTRODUCTION: Laryngotracheal stenosis can be caused after traumatic injuries to the neck from the subglottic larynx to the trachea. Patients with laryngotracheal stenosis often need a tracheotomy and occasionally may become tracheotomy dependent. Different procedures have been described for the management of these lesions. Management options include techniques of endoscopic dilation, laser resection, laryngo-fissure, and an innovative array of plastic reconstructions with or without the use of stents...
March 2016: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27184508/airway-reconstruction-review-of-an-approach-to-the-advanced-stage-laryngotracheal-stenosis
#19
Mohamad Ahmad Bitar, Randa Al Barazi, Rana Barakeh
INTRODUCTION: The management of laryngotracheal stenosis is complex and is influenced by multiple factors that can affect the ultimate outcome. Advanced lesions represent a special challenge to the treating surgeon to find the best remedying technique. OBJECTIVE: To review the efficacy of our surgical reconstructive approach in managing advanced-stage laryngotracheal stenosis treated at a tertiary medical center. METHODS: A retrospective review of all patients that underwent open laryngotracheal repair/reconstruction by the senior author between 2002 and 2014...
April 27, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27113905/the-presentation-and-management-of-granulomatosis-with-polyangiitis-wegener-s-granulomatosis-in-the-pediatric-airway
#20
REVIEW
Pui Y Lee, Eelam A Adil, Alexandria L Irace, Laura Neff, Mary Beth F Son, Edward Y Lee, Antonio Perez-Atayde, Reza Rahbar
OBJECTIVE: Granulomatosis with polyangiitis (GPA) is a necrotizing inflammatory disease that can affect the airway. The purpose of this study was to present a case of pediatric laryngotracheal GPA and provide management recommendations based on a thorough review of the literature. DATA SOURCES: Retrospective chart and literature review REVIEW METHODS: A pediatric patient with laryngotracheal and pulmonary manifestations of GPA who underwent chemotherapy and intralesional corticosteroid injection is described...
April 26, 2016: Laryngoscope
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