keyword
https://read.qxmd.com/read/38560729/clinical-course-of-five-patients-definitively-diagnosed-with-idiopathic-perilymphatic-fistula-treated-with-transcanal-endoscopic-ear-surgery
#21
JOURNAL ARTICLE
Toshinori Kubota, Tsukasa Ito, Takatoshi Furukawa, Hirooki Matsui, Takanari Goto, Chikako Shinkawa, Han Matsuda, Tetsuo Ikezono, Seiji Kakehata
OBJECTIVES: An idiopathic perilymphatic fistula (PLF) can be difficult to diagnose because patients present with sudden sensorineural hearing loss (SSHL) and/or vestibular symptoms without any preceding events. In such cases, we currently test for cochlin-tomoprotein (CTP) to confirm the diagnosis of idiopathic PLF because CTP is only detected in the perilymph. In this study, we report the clinical course of five patients definitively diagnosed with idiopathic PLF who underwent PLF repair surgery using transcanal endoscopic ear surgery (TEES)...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38557194/a-single-dose-of-ac102-restores-hearing-in-a-guinea-pig-model-of-noise-induced-hearing-loss-to-almost-prenoise-levels
#22
JOURNAL ARTICLE
Hans Rommelspacher, Sujoy Bera, Benedikt Brommer, Rachael Ward, Monika Kwiatkowska, Tomasz Zygmunt, Florian Theden, Berk Üsekes, Neriman Eren, Michael Nieratschker, Christoph Arnoldner, Stefan K Plontke, Julian Hellmann-Regen, Reimar Schlingensiepen
Although sudden sensorineural hearing loss (SSNHL) is a serious condition, there are currently no approved drugs for its treatment. Nevertheless, there is a growing understanding that the cochlear pathologies that underlie SSNHL include apoptotic death of sensory outer hair cells (OHCs) as well as loss of ribbon synapses connecting sensory inner hair cells (IHCs) and neurites of the auditory nerve, designated synaptopathy. Noise-induced hearing loss (NIHL) is a common subtype of SSNHL and is widely used to model hearing loss preclinically...
April 9, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38546396/differences-in-semicircular-canal-function-in-the-video-head-impulse-test-in-patients-in-the-chronic-stage-of-sudden-sensorineural-hearing-loss-with-vertigo-and-vestibular-neuritis
#23
JOURNAL ARTICLE
Natsuko Nakamichi, Tomoyuki Shiozaki, Masaharu Sakagami, Tadashi Kitahara
BACKGROUND: Sudden sensorineural hearing loss with vertigo (SHLV) and vestibular neuritis (VN) can result in prolonged dizziness. OBJECTIVES: This study aimed to compare the video head impulse test (vHIT) of patients with SHLV and VN. METHODS: Fifteen patients with SHLV and 21 patients with VN who visited the Vertigo/Dizziness Center of our hospital between December 2016 and February 2023 were included. vHIT was performed at the time of admission, and the VOR gain and catch up saccade (CUS) in the three types of semicircular canals (SCCs) were analyzed...
March 28, 2024: Acta Oto-laryngologica
https://read.qxmd.com/read/38525688/large-vestibular-aqueduct-associated-symptoms-endolymphatic-duct-blockage-as-a-surgical-treatment
#24
JOURNAL ARTICLE
Issam Saliba, Sarah Alshehri, Isabelle Fournier, Nasser Altamami
OBJECTIVE: This study aimed to evaluate the effectiveness of endolymphatic duct blockage (EDB) on dizziness control in patients with a large vestibular aqueduct (LVA) and to evaluate its effect on hearing. STUDY DESIGN: This is a prospective nonrandomized study. SETTING: Five adults and one child with dizziness and five children with progressive hearing loss were referred to our tertiary centers. METHODS: The dizziness handicap inventory (DHI) and DHI-PC (dizziness handicap inventory-patient caregiver) questionnaires were used before and after surgery...
March 18, 2024: Audiology Research
https://read.qxmd.com/read/38525395/the-effect-of-rivaroxaban-in-the-complementary-therapy-of-sudden-sensorineural-hearing-loss
#25
JOURNAL ARTICLE
Mehrdad Rogha, Ehsan Moshtaghi
BACKGROUND: Due to the importance of sudden sensorineural hearing loss (SSNHL) and the possible role of blood coagulation in its mechanism and the likely therapeutic effect of anticoagulants and also the lack of studies in this field, this study aimed to evaluate the effect of rivaroxaban (RXA) in the treatment of this disease. MATERIALS AND METHODS: The present double-blind randomized clinical trial study was performed on 34 patients with SSNHL. Patients were randomly divided into two groups...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38522357/otologic-disease-trends-in-japan-post-covid-19-outbreak-a-retrospective-time-series-analysis
#26
JOURNAL ARTICLE
Keisuke Kondo, Keiji Honda, Keiichi Goshima, Norihiko Inoue, Daisuke Shinjo, Takeshi Tsutsumi, Kiyohide Fushimi
OBJECTIVE: To evaluate the potential impact of coronavirus disease 2019 (COVID-19) and vaccinations on otologic diseases, including facial nerve paralysis (including Ramsay Hunt syndrome), vestibular neuritis, sudden sensorineural hearing loss, and Meniere's disease. METHODS: In this retrospective study, we conducted a time-series analysis employing a causal impact algorithm on a large-scale inpatient database in Japan. We compared the actual number of hospitalized patients with otologic diseases to two predictions: one without any covariates and another with a covariate accounting for the reduction in the number of hospitalized patients due to lockdown measures...
March 23, 2024: Auris, Nasus, Larynx
https://read.qxmd.com/read/38516543/the-association-between-dehydration-and-the-prognosis-of-sudden-sensorineural-hearing-loss
#27
JOURNAL ARTICLE
Yasunori Abe, Masahiro Okada, Keiko Tanaka, Kensuke Toyama, Yoshito Miyamoto, Naohito Hato
BACKGROUND: There is an urgent need to identify undetermined risk factors for sudden sensorineural hearing loss (SSNHL) for the development of effective treatment strategies. SSNHL is likely associated with vascular insufficiency; however, no study has evaluated the relationship between dehydration and SSNHL. OBJECTIVE: This study aimed to investigate the role of dehydration in the development and prognosis of sudden sensorineural hearing loss. STUDY DESIGN: Retrospective case-control study...
December 2023: Otol Neurotol Open
https://read.qxmd.com/read/38516496/bilateral-sudden-hearing-loss-in-iron-deficiency-anemia
#28
Jin Woo Choi, Sung-Yong Kim, Chang-Hee Kim
The present study describes an unusual case of bilateral sudden hearing loss associated with iron deficiency anemia. Although hematologic disorders such as anemia or leukemia have been reported to be associated with sudden hearing loss, bilateral sudden hearing loss, which was presented as the first manifestation of iron deficiency anemia, has not been reported. A 74-year-old man presented with simultaneous bilateral sudden hearing loss without vertigo. A complete blood count test revealed a hemoglobin level of 6...
February 2024: Curēus
https://read.qxmd.com/read/38513512/comparison-of-side-effects-of-different-steroids-used-in-intratympanic-injections
#29
JOURNAL ARTICLE
Yi Wang, Jieli Zhao, Juejing Wu, Tongli Ren, Yongzhen Wu
OBJECTIVES: This study aimed to compare the side effects of different steroids used in the intratympanic injections (IT). METHODS: One hundred and sixty patients diagnosed with sudden sensorineural hearing loss and undergoing IT were assigned to four groups based on the type or concentration of steroids administered (Group DM5: 5 mg/ml Dexamethasone sodium phosphate; Group DM10: 10 mg/ml Dexamethasone sodium phosphate; Group MP: 40 mg/ml Methylprednisolone sodium succinate; Group BM: 4 mg/ml Betamethasone sodium phosphate)...
March 18, 2024: American Journal of Otolaryngology
https://read.qxmd.com/read/38511269/standard-and-extend-high-frequency-audiometry-in-sudden-sensorineural-hearing-loss-impacts-on-tinnitus-and-mental-health
#30
JOURNAL ARTICLE
Andreza Tomaz, Kelly Abdo Peron, Flavia Alencar de Barros Suzuki, Silvia Roberta Gesteira Monteiro, Sujana S Chandrasekhar, Norma Oliveira Penido
OBJECTIVE: To analyze the results of auditory assessment in standard (SA) and extended high-frequency (EHF) audiometry, associating the findings with sudden tinnitus and mental health of patients with unilateral sudden sensorineural hearing loss (SSNHL). STUDY DESIGN: Prospective, cohort study. SETTING: Outpatient otology clinic in a tertiary care hospital. SUBJECTS AND METHODS: Patients experiencing unilateral SSNHL were evaluated with pure-tone audiometry performed at frequencies of 250 to16,000 Hz, tinnitus pitch and loudness matching tests, Tinnitus Handicap Inventory (THI), Analog and Visual Scale (AVS) for bothersome tinnitus, and the Hospital Anxiety and Depression Scale (HADS)...
March 21, 2024: Otology & Neurotology
https://read.qxmd.com/read/38507642/covid-19-vaccination-effects-on-tinnitus-and-hyperacusis-longitudinal-case-study
#31
JOURNAL ARTICLE
Anusha Yellamsetty
The case study explores COVID-19 vaccination connection to tinnitus and hyperacusis, considering its onset and exacerbation post vaccination. The subject is a 47-year-old woman with a history of bilateral tinnitus, and her hearing history was tracked from 2014 to 2023. An intense episode of tinnitus occurred in 2021, distinct from previous experiences post COVID-19 vaccination, second dose. Symptoms manifested as sudden onset of hyperacusis, pronounced "roar" type tinnitus, and a sudden decline in hearing. Audiometric results showed reduce thresholds in low frequencies and lower speech scores in the left ear...
March 21, 2024: International Tinnitus Journal
https://read.qxmd.com/read/38506688/comparison-of-radiofrequency-ablation-and-craniotomy-microvascular-decompression-for-treatment-of-hemifacial-spasm
#32
JOURNAL ARTICLE
Huidan Lin, Shun Zhang, Xiang Gao, Lei Wu, Gang Cao, Lina Xuan, Yuyue Xun, Yongqing Liu, Changshun Huang, Bing Huang
BACKGROUND: Hemifacial spasm (HFS) is distinguished by sudden and involuntary spasms of the facial muscles, predominantly on one side of the face. Microvascular decompression (MVD) is an efficacious surgical technique for treating HFS; however, MVD may occasionally lead to noteworthy postoperative complications. Previously, we reported the successful utilization of an innovative awake computed tomography-guided percutaneous puncture of the stylomastoid foramen for administering radiofrequency ablation (RFA) therapy in the treatment of HFS...
March 2024: Pain Physician
https://read.qxmd.com/read/38506449/prognosis-of-bilateral-sudden-sensorineural-hearing-loss-a-systematic-review-and-meta-analysis
#33
REVIEW
Akash M Bhat, Douglas P Nanu, Shaun A Nguyen, Ted A Meyer, Robert F Labadie
OBJECTIVES: To comprehensively examine the characteristics and prognosis of bilateral sudden sensorineural hearing loss (BSSHL) and its subtypes compared to unilateral sudden sensorineural hearing loss (USSHL). DATA SOURCES: PubMed, Scopus, and CINAHL. REVIEW METHODS: Databases were searched from inception to December 5, 2023, for studies reporting patient characteristics and audiometric outcomes for BSSHL and its simultaneous (Si-BSSHL) and sequential (Se-BSSHL) subtypes...
March 20, 2024: Laryngoscope
https://read.qxmd.com/read/38492552/bone-cement-repair-of-malleus-handle-fractures-intraoperative-video-and-case-report-of-two-patients
#34
Jonathan Olsgård Hansen, Søren Foghsgaard
Isolated malleus fractures are a rare occurrence with few reported cases in the literature. Symptoms include sudden otalgia, hearing loss, tinnitus and aural fullness. Work-up and diagnosis are based on a combination of thorough anamnesis and careful otoscopic evaluation or high-resolution computer tomography. We present two cases of isolated malleus handle fractures who were diagnosed based on a combination of pneumatic otoscopy and tympanometry. Both fractures were surgically repaired using hydroxyapatite bone cement as showcased in the supplemental video material...
March 8, 2024: American Journal of Otolaryngology
https://read.qxmd.com/read/38488157/bilateral-sequential-sudden-hearing-loss-in-a-patient-with-multiple-covid-19-infections-and-potential-implications-on-subsequent-cochlear-implant-performance
#35
JOURNAL ARTICLE
Sharanya Thodupunoori, Stella Cho, Eric Seper, Terence E Imbery, Joshua D Sevier
Viruses are often implicated as a cause of sensorineural hearing loss (SNHL), particularly sudden cases, including COVID-19. Determining the viral mechanism that leads to hearing loss is necessary for its future prevention and treatment. The 47-year-old woman who is the subject of this case study presented with sudden SNHL following multiple infections of COVID-19. Following a trial of a contralateral routing of sound device, she received a right cochlear implant (CI). Following a period of high performance, additional cases of COVID-19 infection and device failure issues resulted in the explant/reimplant of 1 ear and implantation of the contralateral ear...
March 15, 2024: Ear, Nose, & Throat Journal
https://read.qxmd.com/read/38481115/clinical-relevance-of-plasma-lactic-acid-in-the-onset-and-prognosis-of-sudden-deafness
#36
JOURNAL ARTICLE
Ling Wang
Sudden deafness poses a significant threat to patients' quality of life, yet effective indicators for evaluating its onset and prognosis remain elusive. The inner ear is primarily supplied by the labyrinthine artery, which lacks collateral circulation. Changes in coagulation function and hemorheology can cause spasm or thrombosis of the labyrinthine artery, leading to ischemia, hypoxia, and microcirculation disorders in the inner ear, ultimately resulting in sudden deafness. This retrospective study examined 196 patients with sudden deafness, utilizing the 2015 Chinese guideline for diagnosis and treatment classification...
March 13, 2024: Rejuvenation Research
https://read.qxmd.com/read/38465126/exploring-the-impact-of-auditory-hallucinations-on-sudden-sensorineural-hearing-loss-in-adulthood-a-case-report
#37
Camryn Daidone, Hitesh P Rai, Kimberly Loveless
Auditory hallucinations are sounds that patients perceive as coming from outside of their body. Though the mechanism causing auditory hallucinations is not entirely understood, there is a significant amount of evidence suggesting that auditory hallucinations leave lasting impacts on the brain in the same regions that are involved in auditory processing. Sudden sensorineural hearing loss (SSNHL) is a poorly understood condition in which patients lose their hearing typically in the fifth decade of life. Here we present a case of a 42-year-old female with a history of schizophrenia with auditory hallucinations who experienced SSNHL at age 40...
February 2024: Curēus
https://read.qxmd.com/read/38463405/approach-to-sudden-hearing-loss-among-primary-care-physicians-in-riyadh-saudi-arabia
#38
JOURNAL ARTICLE
Nader F Aldajani, Abdulrahman M Aloufi, Nujud A Binhudayb, Buthaina J Yahya, Abdullah F Alkarni
INTRODUCTION: A medical emergency known as sudden sensorineural hearing loss (SSNHL) affects the ears suddenly, has a considerable probability of negative cognitive and functional outcomes, and can influence the patient's quality of life. Primary care physicians play a crucial role in diagnosing SSNHL and initiating prompt and efficient management since they are the ones who would likely encounter it initially. This study aims to evaluate the present knowledge, diagnostic, and management perspective of SSNHL among primary care physicians in Riyadh, Saudi Arabia...
March 2024: Curēus
https://read.qxmd.com/read/38462901/a-comprehensive-study-on-sudden-deafness-for-analyzing-their-clinical-characteristics-and-prognostic-factors
#39
JOURNAL ARTICLE
Kaiwei Yao, Muhammad Asad Iqbal, Nida Fatima Moazzam, Wei Qian
Background: To study the factors associated with the prognosis of patients with sudden deafness to facilitate clinical treatment and improve efficacy. Methods: A total of 414 patients with sudden deafness treated in Zhenjiang First People's Hospital from January 2020 to December 2022 were chosen. Relevant data were gathered and the effectiveness of treatment was assessed by comparing hearing test results before and after hospital admission and divided into effective and ineffective groups, and the effectiveness of each factor was analyzed using univariate analysis, Spearman's correlation analysis, and multifactor logistic regression...
March 10, 2024: Ear, Nose, & Throat Journal
https://read.qxmd.com/read/38461404/red-flags-alerting-a-posterior-cranial-fossa-tumor-from-audiovestibular-perspectives-a-review
#40
REVIEW
Yi-Ho Young, Yi-Hong Wu
BACKGROUND: There is no comprehensive and up-to-date overview of audiovestibular approach to the posterior fossa tumors in the literature. OBJECTIVE: This paper reviewed the literature relating to tumors at the posterior cranial fossa to find red flags alerting a posterior fossa lesion from audiovestibular perspectives. METHODS: This review was developed from articles published in those journals listed on the journal citation reports. Through the PubMed database, Embase, Google Scholar, and Cochrane library, 60 articles were finally obtained based on the PRISMA guidelines for reporting reviews...
January 2024: Acta Oto-laryngologica
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