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https://www.readbyqxmd.com/read/28423374/hyperbaric-oxygen-therapy-as-adjuvant-treatment-for-idiopathic-sudden-sensorineural-hearing-loss-after-failure-of-systemic-steroids
#1
Seiji Hosokawa, Ken-Ichi Sugiyama, Goro Takahashi, Yu-Ichi Hashimoto, Kumiko Hosokawa, Satoru Takebayashi, Hiroyuki Mineta
We evaluated the outcomes of and prognostic factors for idiopathic sudden sensorineural hearing loss (ISSNHL) treated with adjuvant hyperbaric oxygen therapy (HBOT). A retrospective review of clinical data was performed for 167 patients with ISSNHL who failed to respond to systemic steroids and were treated by adjuvant HBOT at Shizuoka Saiseikai General Hospital. We analysed the clinical outcomes, the averaged 5-frequency hearing level after systemic steroids, patient age, the interval between post-steroids and pre-HBOT, vertigo as a complication, the presence of diabetes mellitus, smoking history, and hypertension...
April 20, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28421258/-intralabyrinthine-schwannomas-surgical-management-and-hearing-rehabilitation-with-cochlear-implants-german-version
#2
S K Plontke, T Rahne, M Pfister, G Götze, C Heider, N Pazaitis, C Strauss, P Caye-Thomasen, S Kösling
Intralabyrinthine schwannomas (ILS) are a rare differential diagnosis of sudden hearing loss and vertigo. In an own case series of 12 patients, 6 tumors showed an intracochlear, 3 an intravestibular, 1 a transmodiolar including the cerebello-pontine angle (CPA), 1 a transotic including the CPA and 1 a multilocular location. The tumors were removed surgically in 9 patients, whereas 3 patients opted for a "wait-and-test-and-scan" strategy. Of the surgical patients, 3 underwent labyrinthectomy and cochlear implant (CI) surgery in a single stage procedure; 1 patient received extended cochleostomy with CI surgery; 3 underwent partial or subtotal cochleoectomy, with partial cochlear reconstruction and CI surgery (n = 1) or implantation of electrode dummies for possible later CI following repeated MRI follow-up (n = 2); and in 2 patients, the tumors of the internal auditory canal and cerebellopontile angle exhibiting transmodiolar or transmacular growth were removed by combined translabyrinthine-transotic resection...
April 18, 2017: HNO
https://www.readbyqxmd.com/read/28417108/factors-prognostic-of-season-associated-sudden-sensorineural-hearing-loss-a-retrospective-observational-study
#3
In Yong Ryu, Sang Hyun Park, Eun Bin Park, Ho Joong Kim, Sang Hoon Kim, Seung Geun Yeo
BACKGROUND AND OBJECTIVES: This study examined whether the prognosis of sudden deafness was dependent on the time of onset and evaluated the factors affecting prognosis during each period. SUBJECTS AND METHODS: Patients who developed sudden hearing loss from January 2005 to December 2015 were evaluated retrospectively. Meteorological data were obtained from the official website of the Korea Meteorological Administration. Factors prognostic of hearing recovery rate were analyzed...
April 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28417106/comparative-analysis-of-the-combined-therapeutic-effects-of-lipoprostaglandin-e1-on-sudden-idiopathic-sensorineural-hearing-loss
#4
Haeng Seon Shim, Joon Soo Kim, Myung Gu Kim
BACKGROUND AND OBJECTIVES: Viral and vascular disorders are considered to be a major cause of idiopathic sudden sensorineural hearing loss (ISSNHL). Lipoprostaglandin E1 (lipo-PGE1) has vasodilating activity and has been used to treat ISSNHL. The purpose of this study was to determine the specific therapeutic effects of lipo-PGE1 and compare them to other treatment modalities for ISSNHL. SUBJECTS AND METHODS: The study group had 1,052 patients diagnosed with ISSNHL...
April 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28417102/prognostic-factors-for-recovery-from-sudden-sensorineural-hearing-loss-a-retrospective-study
#5
Woo Seok Kang, Chan Joo Yang, Myungjoo Shim, Chan Il Song, Tae Su Kim, Hyun Woo Lim, Joong Ho Ahn, Hong Ju Park, Jong Woo Chung
BACKGROUND AND OBJECTIVES: This study aimed to investigate prognostic factors in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). SUBJECTS AND METHODS: From January 2007 to December 2011, a retrospective chart review identified 494 consecutive patients with ISSNHL. Demographic, audiometric, and clinical data were analyzed using a logistic regression test. RESULTS: Hearing recovery from ISSNHL was significantly associated with factors such as age, duration from onset of symptoms to commencement of treatment, severity of the initial pure tone threshold, and the treatment method...
April 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28415914/sealing-of-the-round-and-oval-window-niches-with-triamcinolone-soaked-fascia-as-salvage-surgical-therapy-in-sudden-sensorineural-hearing-loss
#6
Benjamin Loader, Rudolf Seemann, Claudia Atteneder, Elisabeth Sterrer, Peter Franz, Claudia Lill
CONCLUSIONS: Triamcinolone-soaked fascia seems to show better hearing improvement when added to tympanotomy for sudden idiopathic sensorineural hearing loss (SSHL), compared to fascia round window occlusion without triamcinolone. OBJECTIVES: To analyse if adding triamcinolone to sealing the round and oval window niches with fascia results in improved audiological outcome for acute SNHL. METHODS: Fifty-three patients (27m:43 ± 12 years, 26f:45 ± 14 years) with acute SSHL ≥50dB over 3 frequencies, who failed primary therapy, underwent transcanal tympanotomy...
April 18, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28414280/neutrophil-to-lymphocyte-and-platelet-to-lymphocyte-ratios-in-pediatric-patients-with-idiopathic-sudden-hearing-loss
#7
Suphi Bulğurcu, Bünyamin Dikilitaş, İlker Burak Arslan, İbrahim Çukurova
OBJECTIVE: We investigated the significance of the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios, which have recently been used in adults for the prognosis of idiopathic sudden hearing loss (ISHL), in the prognosis of idiopathic sudden hearing loss in a pediatric population. MATERIALS AND METHODS: A total of 13 males and 8 females younger than19 years with idiopathic sudden hearing loss were retrospectively examined between January 2008 and August 2016...
April 17, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28414276/studying-the-association-between-sudden-hearing-loss-and-dna-n-methyltransferase-1-dnmt1-genetic-polymorphism
#8
Kübra Şeker Yıldız, Kasım Durmuş, Gonca Dönmez, Serdal Arslan, Emine Elif Altuntaş
OBJECTIVE: The aim of the present study was to investigate whether there was any relationship between some DNA N-methyltransferase 1 (DNMT1) polymorphisms and susceptibility to idiopathic sudden sensorineural hearing loss (ISSHL) in ISSHL patients. MATERIAL AND METHODS: We investigated 90 patients diagnosed with ISSHL and a control group composed of 75 age- and gender-matched healthy individuals. DNA was extracted from the blood samples by phenol-chloroform method...
April 17, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28412992/acute-otitis-media-associated-bilateral-sudden-hearing-loss-case-report-and-literature-review
#9
A Smith, I Gutteridge, D Elliott, M Cronin
BACKGROUND: Sudden sensorineural hearing loss is a rare otological condition with potential for dire outcomes including permanent hearing loss. Although the majority of cases are deemed idiopathic, bilateral sudden sensorineural hearing loss represents a rare subset typically related to systemic conditions, with higher morbidity and mortality. A controversial association with acute otitis media has been reported, with few bilateral cases published in the literature. CASE REPORT: A very rare case of bilateral sudden sensorineural hearing loss associated with acute otitis media is described, with a review of the literature...
April 17, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28397567/framingham-risk-score-as-a-prognostic-predictor-of-sudden-sensorineural-hearing-loss-a-preliminary-study
#10
Young-Soo Chang, Ji Eun Choi, Jungmin Ahn, Nam-Gyu Ryu, Il Joon Moon, Sung Hwa Hong, Yang-Sun Cho, Won-Ho Chung
OBJECTIVES/HYPOTHESIS: Predicting the prognosis of idiopathic sudden sensorineural hearing loss (ISSHL) remains challenging. This investigation aimed to apply Framingham Risk Scores (FRS) to assess the combination of prognostic factors following ISSHL and investigate the predictive role of FRS in patients with multiple comorbidities including hypertension, diabetes, and hyperlipidemia. STUDY DESIGN: Retrospective study. METHODS: Twenty-one patients presenting with unilateral idiopathic sudden sensorineural hearing loss and multiple comorbidities were surveyed...
May 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28397037/assessment-of-balance-and-vestibular-functions-in-patients-with-idiopathic-sudden-sensorineural-hearing-loss
#11
Jia Liu, Ren-Hong Zhou, Bo Liu, Yang-Ming Leng, Jing-Jing Liu, Dong-Dong Liu, Su-Lin Zhang, Wei-Jia Kong
This study investigated the relationship among the severity of hearing impairment, vestibular function and balance function in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). A total of 35 ISSNHL patients (including 21 patients with vertigo) were enrolled. All of the patients underwent audiometry, sensory organization test (SOT), caloric test, cervical vestibular-evoked myogenic potential (cVEMP) test and ocular vestibular-evoked myogenic potential (oVEMP) test. Significant relationship was found between vertigo and hearing loss grade (P=0...
April 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28394652/nationwide-epidemiological-survey-of-idiopathic-sudden-sensorineural-hearing-loss-in-japan
#12
Ryosuke Kitoh, Shin-Ya Nishio, Kaoru Ogawa, Sho Kanzaki, Naohito Hato, Michihiko Sone, Satoshi Fukuda, Akira Hara, Tetsuo Ikezono, Kotaro Ishikawa, Satoshi Iwasaki, Kimitaka Kaga, Seiji Kakehata, Atsushi Matsubara, Tatsuo Matsunaga, Takaaki Murata, Yasushi Naito, Takashi Nakagawa, Kazunori Nishizaki, Yoshihiro Noguchi, Hajime Sano, Hiroaki Sato, Mikio Suzuki, Hideo Shojaku, Haruo Takahashi, Hidehiko Takeda, Testuya Tono, Hiroshi Yamashita, Tatsuya Yamasoba, Shin-Ichi Usami
OBJECTIVES: Using a large-scale nationwide survey database, we investigated the epidemiological characteristics for idiopathic SSNHL in Japan. METHODS: The subjects for this analysis were patients registered in a Japanese multicentre database between April 2014 and March 2016. A total of 3419 idiopathic SSNHL patients were registered in the database, and the clinical characteristics of the idiopathic SSNHL patients were obtained. Several factors associated with the severity of hearing impairment and prognosis were then investigated...
April 10, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28385715/sudden-sensorineural-hearing-loss
#13
Christopher Joseph Chin, Kathryn Dorman
No abstract text is available yet for this article.
March 20, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28384627/simultaneous-versus-sequential-intratympanic-steroid-treatment-for-severe-to-profound-sudden-sensorineural-hearing-loss
#14
Myung Hoon Yoo, Won Sub Lim, Joo Hyun Park, Joong Keun Kwon, Tae-Hoon Lee, Yong-Hwi An, Young-Jin Kim, Jong Yang Kim, Hyun Woo Lim, Hong Ju Park
OBJECTIVES: Severe-to-profound sudden sensorineural hearing loss (SSNHL) has a poor prognosis. We aimed to compare the efficacy of simultaneous and sequential oral and intratympanic steroids for this condition. METHODS: Fifty patients with severe-to-profound SSNHL (>70 dB HL) were included from 7 centers. The simultaneous group (27 patients) received oral and intratympanic steroid injections for 2 weeks. The sequential group (23 patients) was treated with oral steroids for 2 weeks and intratympanic steroids for the subsequent 2 weeks...
April 7, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28384326/increased-risk-of-sudden-sensorineural-hearing-loss-in-patients-with-hepatitis-virus-infection
#15
Hsin-Chien Chen, Chi-Hsiang Chung, Chih-Hung Wang, Jung-Chun Lin, Wei-Kuo Chang, Fu-Huang Lin, Chang-Huei Tsao, Yung-Fu Wu, Wu-Chien Chien
The etiology of sudden sensorineural hearing loss (SSNHL) remains unclear. Possible causes of SSNHL include vascular diseases, viral infection, and autoimmune disorders. Therefore, we investigated whether hepatitis virus infection is correlated with the risk of SSNHL. Using data from the Taiwan Longitudinal Health Insurance Database, we conducted a retrospective matched-cohort study to compare patients diagnosed with hepatitis B or C virus (HBV/HCV) infections from January 1, 2000, to December 31, 2010, (N = 170,942) with frequency-matched controls (N = 512,826) at a ratio of 1:3 by sex, age, and index year...
2017: PloS One
https://www.readbyqxmd.com/read/28376930/predictors-of-hearing-recovery-in-patients-with-severe-sudden-sensorineural-hearing-loss
#16
Daniel Weiss, Armin Julius Böcker, Mario Koopmann, Eleftherios Savvas, Matthias Borowski, Claudia Rudack
BACKGROUND: Sudden sensorineural hearing loss (SSHL) is a disease, which severely affects the patient's social and relational life. The underlying pathomechanisms have not been finally clarified yet and outcome is not predictable. METHODS: We conducted a retrospective study in order to identify parameters that influence hearing recovery. The data base contains results of basic otoneurological tests and clinical parameters of 198 patients with idiopathic SSHL of at least 60 dB in at least four frequencies, diagnosed and treated at the University Hospital of Münster, Germany, between 1999 and 2015...
April 4, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28369007/drug-induced-defibrinogenation-as-new-treatment-approach-of-acute-hearing-loss-in-an-animal-model-for-inner-ear-vascular-impairment
#17
Bernhard G Weiss, Mattis Bertlich, Stephan A Bettag, Hendrik Desinger, Friedrich Ihler, Martin Canis
OBJECTIVE: Disturbance of cochlear microcirculation is considered to be the final common pathway of various inner ear diseases. Hyperfibrinogenemia causing increased plasma viscosity is a known risk factor for sudden sensorineural hearing loss and may lead to a critical reduction of cochlear blood flow. The aim of this study was to evaluate the effect of a substantial reduction of plasma fibrinogen levels by drug-induced defibrinogenation for the treatment of acute hearing loss in vivo...
March 31, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28366808/calpain-inhibitor-alleviates-permanent-hearing-loss-induced-by-intense-noise-by-preventing-disruption-of-gap-junction-mediated-intercellular-communication-in-the-cochlear-spiral-ligament
#18
Taro Yamaguchi, Masanori Yoneyama, Kiyokazu Ogita
Our previous studies demonstrated that intense noise-induced hearing loss might be at least in part due to an oxidative stress-induced decrease in the level of gap junction-composing protein connexins in the spiral ligament (SL) of the cochlear lateral wall structures in mice. Further, an in vivo exposure of mice to intense noise activates calpain in the cochlear SL. Based on these studies, we sought to determine whether a calpain inhibitor would prevent an intense noise exposure from causing hearing loss, disruption of gap junction-mediated intercellular communication (GJIC) in the SL...
March 30, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28366083/idiopathic-sudden-sensorineural-hearing-loss-and-acute-low-tone-sensorineural-hearing-loss-a-comparison-of-the-results-of-a-nationwide-epidemiological-survey-in-japan
#19
Tadao Yoshida, Michihiko Sone, Ryosuke Kitoh, Shin-Ya Nishio, Kaoru Ogawa, Sho Kanzaki, Naohito Hato, Satoshi Fukuda, Akira Hara, Tetsuo Ikezono, Kotaro Ishikawa, Satoshi Iwasaki, Kimitaka Kaga, Seiji Kakehata, Atsushi Matsubara, Tatsuo Matsunaga, Takaaki Murata, Yasushi Naito, Takashi Nakagawa, Kazunori Nishizaki, Yoshihiro Noguchi, Hajime Sano, Hiroaki Sato, Mikio Suzuki, Hideo Shojaku, Haruo Takahashi, Hidehiko Takeda, Testuya Tono, Hiroshi Yamashita, Tatsuya Yamasoba, Shin-Ichi Usami
OBJECTIVES: The aim of this study was to investigate the differences between idiopathic sudden sensorineural hearing loss (SSNHL), and acute low-tone sensorineural hearing loss (ALHL) using the results of a nationwide survey database in Japan and to analyze the variables associated with their clinical features and the severity of hearing impairment, treatment, and prognosis. METHODS: Participants were patients registered between April 2014 and March 2016 in a multicenter epidemiological survey database involving 30 university hospitals and medical centers across Japan...
April 1, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28366076/relationships-among-drinking-and-smoking-habits-history-of-diseases-body-mass-index-and-idiopathic-sudden-sensorineural-hearing-loss-in-japanese-patients
#20
Mitsumasa Umesawa, Gen Kobashi, Ryoshuke Kitoh, Shin-Ya Nishio, Kaoru Ogawa, Naohito Hato, Michihiko Sone, Satoshi Fukuda, Akira Hara, Tetsuo Ikezono, Kotaro Ishikawa, Satoshi Iwasaki, Kimitaka Kaga, Seiji Kakehata, Atsushi Matsubara, Tatsuo Matsunaga, Takaaki Murata, Yasushi Naito, Takashi Nakagawa, Kazunori Nishizaki, Yoshihiro Noguchi, Hajime Sano, Hiroaki Sato, Mikio Suzuki, Hideo Shojaku, Haruo Takahashi, Hidehiko Takeda, Tetsuya Tono, Hiroshi Yamashita, Tatsuya Yamasoba, Shin-Ichi Usami
OBJECTIVES: To present the cardiovascular risk factors in idiopathic sudden sensorineural hearing loss (SSNHL) patients enrolled in a nationwide epidemiological survey of hearing disorders in Japan. MATERIALS AND METHODS: We compiled the cardiovascular risk factors in 3073 idiopathic SSNHL subjects (1621 men and 1452 women) and compared their proportions with controls as part of the National Health and Nutrition Survey in Japan, 2014. The cardiovascular risk factors consisted of drinking and smoking habits, a history of five conditions related to cardiovascular disease and body mass index...
April 1, 2017: Acta Oto-laryngologica
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