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https://www.readbyqxmd.com/read/29777372/cardiac-surgery-2017-reviewed
#1
REVIEW
Torsten Doenst, Hristo Kirov, Alexandros Moschovas, David Gonzalez-Lopez, Rauf Safarov, Mahmoud Diab, Steffen Bargenda, Gloria Faerber
For the year 2017, more than 21,000 published references can be found in PubMed when entering the search term "cardiac surgery". This review focusses on conventional cardiac surgery, considering the new interventional techniques only if they were directly compared to classic techniques but also entails aspects of perioperative intensive care management. The publications last year provided a plethora of new and interesting information that helped to quantify classic surgical treatment effects and provided new guidelines for the management of structural heart disease, which made comparisons to interventional techniques easier...
May 17, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29764497/activated-prothrombin-complex-concentrate-to-reverse-the-factor-xa-inhibitor-apixaban-effect-before-emergency-surgery-a-case-series
#2
Nina Haagenrud Schultz, Runar Lundblad, Pål Andre Holme
BACKGROUND: The lack of an antidote against factor Xa inhibitors in case of major bleeding or need for urgent surgery is a concern to clinicians. Guidelines on managing major bleeding in patients under anticoagulation with a factor Xa inhibitor suggest several hemostatic agents to reverse the effect, but there is no consensus regarding the choice of drug or appropriate dose. The ability of prothrombin complex concentrate, activated prothrombin complex concentrate, and recombinant factor VIIa to reverse the effect of factor Xa inhibitors has been evaluated in animal studies, in vitro studies, and healthy volunteers, but not yet in randomized clinical studies...
May 16, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29706203/complications-of-radiofrequency-ablation-for-supraventricular-tachycardia-in-the-wolff-parkinson-white-syndrome-associated-with-noncompaction-cardiomyopathy
#3
William C Roberts, Paul A Grayburn, Shelley A Hall
Described herein is a 52-year-old man with Wolff-Parkinson-White syndrome and noncompaction cardiomyopathy who underwent 4 sternotomies to correct complications of 3 ablation procedures (2 open) for recurring supraventricular tachycardia, mitral valve repair for a damaged mitral valve during the third radiofrequency ablation procedure, and finally orthotopic heart transplantation.
March 23, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29702648/development-of-a-cardiac-loading-device-to-monitor-cardiac-function-during-ex-vivo-graft-perfusion
#4
Emilie Farine, Manuel U Egle, Alice C Boone, Sandro Christensen, Thierry P Carrel, Hendrik T Tevaearai Stahel, Sarah L Longnus
BACKGROUND: Ex vivo heart perfusion systems, allowing continuous perfusion of the coronary vasculature, have recently been introduced to limit ischemic time of donor hearts prior to transplantation. Hearts are, however, perfused in an unloaded manner (via the aorta) and therefore, cardiac contractile function cannot be reliably evaluated. OBJECTIVES: We aim to develop a ventricular loading device that enables monitoring of myocardial function in an ex vivo perfusion system...
2018: PloS One
https://www.readbyqxmd.com/read/29701175/sclerostin-is-not-associated-with-cardiovascular-event-or-fracture-in-kidney-transplantation-candidates
#5
Hanne Skou Jørgensen, Simon Winther, Laust Dupont, Morten Bøttcher, Lars Rejnmark, Ellen-Margrethe Hauge, My Svensson, Per Ivarsen
BACKGROUND: Sclerostin, a bone-derived protein, has been linked to cardiovascular calcifications in chronic kidney disease (CKD). The aim of this study was to investigate the associations between sclerostin and mineral and bone disorder in CKD, specifically whether sclerostin levels could predict cardiovascular event, fracture, or all-cause mortality. MATERIALS AND METHODS: Kidney transplantation candidates (n = 157) underwent computed tomography scans of the chest, abdomen, and pelvis...
April 27, 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29688916/gastrointestinal-bleeding-with-left-ventricular-assist-devices-lvad-locating-the-leak-and-identifying-outcomes
#6
Sarah Malik, Shahbaz A Malik, Laura L Ulmer, Lokesh K Jha, Michael S Strupp, Eugenia Raichlin, Elizabeth R Lyden, Alexander T Hewlett
BACKGROUND AND GOALS: Gastrointestinal bleeding (GIB) is a significant complication following left ventricular assist device (LVAD) implantation. We evaluated the incidence, predictors, endoscopic findings, and outcomes of GIB in LVAD recipients. STUDY: Retrospective review of 205 adult patients undergoing HeartMate II LVAD implantation from January 2012 to June 2016. Patients were reviewed and separated into GIB (n=57; 28%) and non-GIB (n=148; 72%) groups. RESULTS: Median time to GIB was 55 (range, 3 to 730) days...
April 23, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29679990/three-dimensional-echocardiographic-evaluation-of-ebstein-s-anomaly-of-the-tricuspid-valve-in-a-patient-with-hypoplastic-left-heart-syndrome
#7
Courtney Cassidy, Max B Mitchell, Pei-Ni Jone
We report three-dimensional imaging of a rare finding of Ebstein's anomaly of the tricuspid valve in a patient with hypoplastic left heart syndrome, which has been previously reported only by two-dimensional echocardiography. A fetal echocardiogram was performed at 19 weeks that showed a moderately hypoplastic left ventricle, severely hypoplastic mitral valve, a severely hypoplastic aortic valve, and a dysplastic tricuspid valve. Post Caesarean delivery at 40 weeks of gestation, a transthoracic echocardiogram confirmed the findings seen on the fetal echocardiogram...
April 22, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29667250/a-new-2d-echocardiographic-approach-to-evaluate-the-membrane-and-valve-movement-of-the-berlin-heart-excor-vad-chamber-in-pediatric-vad-patients
#8
Arianna Di Molfetta, Roberta Iacobelli, Gianfranco Ferrari, Sergio Filippelli, Gianluigi Perri, Alessandra Toscano, Rachele Adorisio, Paolo Guccione, Antonio Amodeo
The use of Berlin Heart EXCOR VAD (BH) is a validated therapy to bridge pediatric patients to heart transplant. Serial echocardiographic (ECHO) assessment of VAD patients is necessary to support patients' management. This work aims at developing an innovative strategy to evaluate the BH device functioning by ECHO and its interaction with the native heart in a pediatric population. ECHO evaluation of BH membrane movement, and inflow and outflow valves was performed in 2D, 2D-color Doppler, M-mode, and M-mode color Doppler to assess the functioning of the device by direct positioning of the ECHO probe on the BH cannulas and membranes...
April 2018: Artificial Organs
https://www.readbyqxmd.com/read/29657239/application-of-a-fresh-decellularized-pulmonary-allograft-for-pulmonary-valve-replacement-in-japan
#9
Hideto Ozawa, Takayoshi Ueno, Masaki Taira, Koichi Toda, Toru Kuratani, Yoshiki Sawa
BACKGROUND: Tissue engineering has advanced the technique of decellularization of the heart valve. The valve is reseeded with the patient's own cells after implantation with suppression of immunologic reactions. The same advantage has been reported for fresh decellularized heart valves, and more than 10 years of excellent outcomes have been achieved. We began performing such heart valve implantations in 2013 as part of a clinical study at Osaka University. We report our evaluation of the safety and efficacy of heart valve implantation...
April 14, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29655822/clinical-spectrum-and-management-of-heart-failure-in-hypertrophic-cardiomyopathy
#10
REVIEW
Barry J Maron, Ethan J Rowin, James E Udelson, Martin S Maron
Heart failure (HF), characterized by excessive exertional dyspnea, is a common complication within the broad clinical spectrum of hypertrophic cardiomyopathy (HCM). HF has become an increasingly prominent management issue with the reduction in sudden deaths due to use of implantable defibrillators in this disease. Exertional dyspnea ranges in severity from mild to severe (New York Heart Association functional classes II to IV) and not uncommonly becomes refractory to medical management, leading to progressive disability, but largely in the absence of pulmonary congestion and volume overload requiring hospitalization...
May 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/29628209/outcomes-in-patients-with-short-bowel-syndrome-after-autologous-intestinal-reconstruction-does-etiology-matter
#11
Federica Pederiva, Alberto Sgrò, Riccardo Coletta, Basem Khalil, Antonino Morabito
BACKGROUND: Short bowel syndrome (SBS) is the most common cause of intestinal failure in children. Many factors have been investigated in an attempt to define which parameters influence most survival and ability to wean off parenteral nutrition (PN). The aim of this study was to investigate if aetiology of SBS affects the outcomes in paediatric patients treated with autologous gastrointestinal reconstructive surgery. METHODS: All children with SBS who underwent autologous gastrointestinal reconstructive surgery between 2002 and 2012 were retrospectively reviewed and outcome measures were recorded...
March 12, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29622705/native-valve-endocarditis-fusarium-and-end-stage-renal-disease
#12
Supradip Ghosh, Atul Phillips, Sonali Ghosh, Amandeep Singh
We would like to report a case of invasive Fusariosis involving the native mitral valve and complicated by septic thromboembolism. The patient was a known case of end-stage renal disease on maintenance haemodialysis and did not have any of the known risk factors for invasive Fusariosis like neutropaenia, severe T cell immunodeficiency, postsolid organ transplant recipients, posthaematopoietic stem cell transplant recipients and patients who received cytotoxic and/or high-dose corticosteroid therapy.
April 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29607974/silent-native-valve-endocarditis-caused-by-propionibacterium-acnes
#13
Rintaro Yamamoto, Shigeru Miyagawa, Hideharu Hagiya, Keigo Kimura, Isao Nishi, Norihisa Yamamoto, Hisao Yoshida, Yukihiro Akeda, Kazunori Tomono, Koichi Toda, Yoshiki Sawa
We describe a rare case of Propionibacterium acnes native-valve endocarditis that silently progressed in a 67-year-old man with hybrid dialysis. The patient was scheduled for kidney transplantation, and pre-operative investigation incidentally detected a vegetative structure at his native mitral valve that had increased in size. He underwent cardiac surgery and P. acnes was detected in cultures of a resected cardiac valve specimen and blood. This case highlights that P. acnes can silently cause infective endocarditis in a native-valve, and that physicians should consider the possibility of infection when P...
March 30, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29603533/aspergillus-flavus-native-valve-endocarditis-following-combined-liver-and-renal-transplantation-case-report-and-review-of-the-literature
#14
Sultan Alsobayeg, Nada Alshehri, Shamayel Mohammed, Bahaa M Fadel, Ali S Omrani, Reem Almaghrabi
Fungal endocarditis is a rare but serious form of infective endocarditis, typically involving prosthetic valves and resulting in high morbidity and mortality[1]. Fungi account for 1.3-6% of all cases of infective endocarditis, out of which Candida species are the most common, followed by Aspergillus species (25-30%)[1-3]. The most frequest risk factors for fungal endocarditis include cardiac surgery, indwelling vascular devices and intravenous drug use. However, fungal endocarditis of the native cardiac valves is extremely unusual[4]...
March 30, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29582947/-long-term-follow-up-of-transcatheter-self-expandable-aortic-valve-implantation
#15
Shmuel Chen, Vicky Zenios, Dan Gilon, David Planer, Ronen Beeri, Chaim Lotan, Haim D Danenberg
INTRODUCTION: Aortic stenosis is the most common significant valvular disease in the western world. These patients are treated operatively unless they are at high operative risk or inoperable. During the last decade an alternative approach has evolved - transcatheter aortic valve implantation (TAVI). This method was shown to be at least as effective and safe as the operative one. However, very little data exists on long term follow-up (5 years and above), especially regarding valve durability and patient survival...
March 2018: Harefuah
https://www.readbyqxmd.com/read/29579810/trend-analysis-of-organ-and-tissue-donation-for-transplantation
#16
M J Dos Santos, E Leal de Moraes, M Santini Martins, E Carlos de Almeida, L Borges de Barros E Silva, V Urias, M C Silvano Corrêa Pacheco Furtado, Á Brito Nunes, S El Hage
BACKGROUND: The goal of this study was to identify the tendency toward donations of tissue and organs from donors with brain death between 2001 and 2016 as registered by an organ procurement organization in São Paulo City. METHODS: This quantitative, retrospective, exploratory study encompassed all Tissue and Organ Donation Terms signed between 2001 and 2016. A logistic regression model was applied to verify whether there was an upward or downward trend in donation...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29575395/cost-effectiveness-of-endobronchial-valve-treatment-in-patients-with-severe-emphysema-compared-to-standard-medical-care
#17
Jorine E Hartman, Karin Klooster, Henk Groen, Nick H T Ten Hacken, Dirk-Jan Slebos
BACKGROUND AND OBJECTIVE: Bronchoscopic lung volume reduction using endobronchial valves (EBV) is an effective new treatment option for severe emphysema patients without interlobar collateral ventilation. The objective of this study was to perform an economic evaluation including the costs and cost-effectiveness of EBV treatment compared with standard medical care (SoC) from the hospital perspective in the short term and long term. METHODS: For the short-term evaluation, incremental cost-effectiveness ratios (ICER) were calculated based on the 6-month end point data from the STELVIO randomized trial...
March 25, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29571631/vitrification-of-aortic-valve-homografts-suppresses-nlrp3-inflammasome-activation-and-alleviates-the-inflammatory-response-after-transplantation
#18
Yulong Sui, Bin Wang, Qing Fan, Wenjie Zhu, Jixian Wang, Qing Chang
No abstract text is available yet for this article.
March 20, 2018: Cryobiology
https://www.readbyqxmd.com/read/29549696/dilatation-of-aortic-root-in-patients-after-kidney-transplantation
#19
Marta Obremska, Maria Boratyńska, Maciej Szymczak, Dorota Zyśko, Tomasz Płonek, Anna Goździk, Marian Klinger
INTRODUCTION    The dilatation of aortic root (AoR) correlates with cardiac damage and higher cardiovascular risk. The cardiovascular disease is the most common cause of death in patient after kidney transplantation ( KTX). OBJECTIVES    The aim of this study was to assess the prevalence of enlarged AoR diameter in patient after KTX. Patients with  bicuspid aortic valve, significant valvular disease or evidence of connective tissue disorder were excluded. PATIENTS AND METHODS    The all 87 patients after KTX were divided into 2 groups depend on immunosuppressive regimen :mTORi group: 41 patients treated with mammalian target of rapamycin inhibitors  and CNI group: 46 with calcineurin inhibitors...
March 17, 2018: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/29546810/total-artificial-heart-implantation-in-a-young-marfan-syndrome-patient
#20
Prashant Rao, Jack B Keenan, Taufiek K Rajab, Samuel Kim, Richard Smith, Orazio Amabile, Zain Khalpey
INTRODUCTION: Cardiovascular complications represent the leading cause of morbidity and mortality in patients with Marfan syndrome. Here, we describe a unique case where a total artificial heart was implanted in a young Marfan syndrome woman. METHODS: A 22-year-old postpartum African American female with Marfan syndrome developed multiple severe valve dysfunction and biventricular failure that was refractory to medical management. She previously had a Bentall procedure for Type A aortic dissection and repair of a Type B dissection...
March 2018: International Journal of Artificial Organs
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