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Biochemical reference values

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https://www.readbyqxmd.com/read/29324913/the-detection-of-endocarditis-post-implantation-grafts-arteritis-and-other-related-disorders-by-18f-fdg-pet-ct
#1
Jelena Šaponjski, Dragana Šobić-Šaranović, Strahinja Odalović, Milica Stojiljković, Jelena Pantović, Nebojša Petrović, Isidora Grozdić-Milojević, Vera Artiko
INTRODUCTION: Positron emission tomography with computed tomography (18F-FDG PET/CT) is a nuclear medicine diagnostic method which, unlike other technological modalities that asses anatomical features, detects increased glucose metabolism inside the cells, thus is very helpful in diagnosing cardiovascular infection and inflammation and also in therapy planning. AIM: Aim of this study was to assess the significance of 18F-FDG PET/CT in detection of an active disease in patients with infection and inflammation of cardiovascular system...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29323425/evaluating-mid-upper-arm-circumference-z-score-as-a-determinant-of-nutrition-status
#2
Karen Stephens, April Escobar, Erika Nicole Jennison, Lindsey Vaughn, Rhonda Sullivan, Susan Abdel-Rahman
BACKGROUND: Mid-upper arm circumference (MUAC) z-score, has recently been listed as an independent indicator for pediatric malnutrition. This investigation examined the relationship between MUAC z-score and the z-scores for conventional indicators (ie, weight-for-length and body mass index) to expand the available evidence for nutrition classification z-score threshold ranges in U.S. practice settings. METHODS: This was a single-center study of children through 18 years of age seen between October 2015 and September 2016...
January 11, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29320333/prostate-specific-membrane-antigen-pet-clinical-utility-in-prostate-cancer-normal-patterns-pearls-and-pitfalls
#3
Michael S Hofman, Rodney J Hicks, Tobias Maurer, Matthias Eiber
Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein that is overexpressed in prostate cancer. Radiolabeled small molecules that bind with high affinity to its active extracellular center have emerged as a potential new diagnostic standard of reference for prostate cancer, resulting in images with extraordinary tumor-to-background contrast. Currently, gallium 68 (68Ga)-PSMA-11 (or HBED-PSMA) is the most widely used radiotracer for PSMA positron emission tomography (PET)/computed tomography (CT) or PSMA PET/magnetic resonance (MR) imaging...
January 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29303769/reference-intervals-for-biochemical-haemostatic-and-haematological-parameters-in-healthy-chinese-women-during-early-and-late-pregnancy
#4
Yi Jin, Jie Lu, Hong Jin, Chunrong Fei, Xinyou Xie, Jun Zhang
BACKGROUND: Variations in maternal blood parameters, which are mostly induced by the physiological changes that occur during pregnancy, have been reported in different gestational periods. The use of the established reference intervals for healthy adult females leads to the misclassification of healthy pregnant women as abnormal. Our aim was to establish appropriate reference intervals for biochemical, haematological and haemostatic parameters in the first and third trimesters of pregnancy...
January 5, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29280047/an-evaluation-of-the-protective-effect-of-esomeprazole-in-an-experimental-model-of-renal-ischemia-reperfusion
#5
Tayyar Alp Ozkan, Nihat Karakoyunlu, Reyhan Polat, Gülistan Sanem Sarıbaş, Nevzat Can Şener, Seyda Özdemir, Kevser Peker, Dilek Ünal, Can Tuygun
PURPOSE: The ischemia and subsequent reperfusion (IR) which occurs in partial nephrectomy used in the treatment of renal tumors causes loss of parenchyma in the damaged kidney. The aim of this study is to evaluate, both biochemically and histologically, the efficacy of esomeprazole in an ischemia-reperfusion model in rat kidneys. METHODS: The rats were randomized into three groups of seven animals each, referred to as the sham, control, and PPI groups. In the sham group, only a laparotomy was performed...
December 26, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/29278630/predictive-value-of-high-sensitive-troponin-i-assay-in-acute-coronary-syndrome-compared-to-classic-biochemical-markers
#6
Tomislav Čolak, Ivanka Mikulić, Kristina Landeka, Ana Sesar, Marija Vranješ, Ivanka Mikulić
The aims of this study were to compare predictive values of hsTroponin I assay with contemporary assays and its usefulness in diagnosis of acute coronary syndrome (ACS). We also aimed to determine reference values of the assay and the possibility of fast ACS diagnosis using hsTnI. The study included 26 patients with ongoing chest pains and suspected ACS. ACS diagnosis was determined using electrocardiographic changes and international guidelines. Biochemical parameters were measured using standard tests which included Troponin I, hsTroponin I, CK, CK-MB and CRP...
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29275044/functional-and-proteomic-comparison-of-bothrops-jararaca-venom-from-captive-specimens-and-the-brazilian-bothropic-reference-venom
#7
Iasmim Baptista de Farias, Karen de Morais-Zani, Caroline Serino-Silva, Sávio S Sant'Anna, Marisa M T da Rocha, Kathleen F Grego, Débora Andrade-Silva, Solange M T Serrano, Anita M Tanaka-Azevedo
Snake venom is a variable phenotypic trait, whose plasticity and evolution are critical for effective antivenom production. A significant reduction of the number of snake donations to Butantan Institute (São Paulo, Brazil) occurred in recent years, and this fact may impair the production of the Brazilian Bothropic Reference Venom (BBRV). Nevertheless, in the last decades a high number of Bothrops jararaca specimens have been raised in captivity in the Laboratory of Herpetology of Butantan Institute. Considering these facts, we compared the biochemical and biological profiles of B...
December 21, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/29258577/biochemistry-reference-intervals-for-healthy-elderly-population-in-asmara-eritrea
#8
Oliver Okoth Achila, Paulos Semere, Danait Andemichael, Harerta Gherezgihier, Senait Mehari, Adiam Amanuel, Tedalo Yohannes, Eyob Yohaness, Tzegezeab Goje
OBJECTIVE: There is a scarcity of reference interval studies on the elderly in Africa. This study establishes reference interval for the elderly for some commonly used biochemical parameters. In this study, 255 conveniently sampled, healthy elderly, participants meeting Clinical and Laboratory Standards Institute (CLSI C28-A3) guidelines were enrolled. The results obtained may have utility in clinical diagnosis, patient management and research. RESULTS: In general, the consensus reference interval established in this study tended to be higher than reference interval from Caucasian populations; but lower than those obtained from reference interval studies in several African countries...
December 19, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29248450/evaluating-the-hematological-and-clinical-chemistry-parameters-of-kratom-mitragyna-speciosa-users-in-malaysia
#9
Darshan Singh, Christian P Müller, Vikneswaran Murugaiyah, Shahrul Bariyah Sahul Hamid, Balasingam K Vicknasingam, Bonnie Avery, Nelson Jeng Yeou Chear, Sharif Mahsufi Mansor
ETHNOPHARMACOLOGICAL RELEVANCE: Kratom (Mitragyna speciosa Korth.) from the Rubiaceae family is an indigenous tropical medicinal tree of Southeast Asia. Kratom leaves have been used for decades in Malaysia and Thailand in traditional context for its perceived vast medicinal value, and as a mild stimulant among manual labourers. Kratom consumption has been reported to cause side-effects in kratom users. AIM OF THE STUDY: To evaluate kratom's effects towards hematological and clinical-chemistry parameters among regular kratom users in Malaysia...
December 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29244257/normal-reference-intervals-and-the-effects-of-sample-handling-on-dynamic-viscoelastic-coagulometry-sonoclot-in-healthy-adult-horses
#10
Camilla A Jamieson, Andrew S Hanzlicek, Mark E Payton, Todd C Holbrook
OBJECTIVE: To determine reference intervals and the effect of sample agitation and rest time on Sonoclot analysis in healthy adult horses. DESIGN: Original prospective study. SETTING: University veterinary medical teaching hospital. ANIMALS: Sixty healthy adult horses. INTERVENTIONS: Blood was collected for assessment of complete blood count, serum biochemical analysis, and Sonoclot analysis. MEASUREMENTS AND MAIN RESULTS: Horses were determined to be healthy based upon physical examination, CBC, and serum biochemistry analysis...
January 2018: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/29242398/actual-impact-of-68ga-psma-11-pet-ct-on-the-management-of-prostate-cancer-patients-with-biochemical-recurrence
#11
Jérémie Calais, Wolfgang P Fendler, Matthias Eiber, Jeannine Gartmann, Fang-I Chu, Nicholas G Nickols, Robert R Reiter, Matthew B Rettig, Leonard S Marks, Thomas E Ahlering, Lynda Huynh, Roger Slavik, Pawan Gupta, Andrew Quon, Martin S Allen-Auerbach, Johannes Czernin, Ken Herrmann
Purpose: In this prospective survey of referring physicians, we investigated whether and how Gallium-68 Prostate Specific Membrane Antigen Positron Emission Tomography/Computed Tomography (PSMA-11 PET/CT) affects the actually implemented management of prostate cancer patients wih biochemical recurrence (BCR). Methods: We conducted a prospective survey of physicians (NCT02940262) who referred 161 patients with prostate cancer BCR (median Prostate Specific Antigen (PSA) value 1.7 ng/ml (range 0.05-202)). Referring physicians completed one questionnaire prior to the scan to indicate the treatment plan without PSMA-11 PET/CT information (Q1; n = 101); one immediately after the scan to denote intended management changes (Q2; n = 101); and one 3 to 6 months later to document the final implemented management (Q3; n = 56)...
December 14, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29226638/reference-values-of-certain-serum-indicators-of-liver-fibrosis
#12
Blagovesta Pencheva, Rossen Mihajlov, Adelaida Ruseva, Rumyana Mitova, Kaloyan Petrov, Gergana Taneva, Jordan Genov
BACKGROUND: Liver fibrosis shows a continuously increasing trend worldwide, due to alcohol abuse, obesity, and, to a lesser extent, chronic hepatitis B and C. Biopsy is still considered the "gold standard" for diagnosis of liver fibrosis. However, it has a number of limitations, such as invasiveness, high cost, need for specialists to conduct and interpret biopsy results, risk of complications, inability to dynamically monitor the pathological process, low patient compliance, and uneven fibrosis distribution...
November 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29195794/design-synthesis-and-pharmacological-evaluation-of-some-novel-indanone-derivatives-as-acetylcholinesterase-inhibitors-for-the-management-of-cognitive-dysfunction
#13
Poonam Piplani, Ankit Jain, Dhiksha Devi, Anjali, Anuradha Sharma, Pragati Silakari
The present study reports the effect of indanone derivatives on scopolamine induced deficit cholinergic neurotransmission serving as promising leads for the therapeutics of cognitive dysfunction. Eleven compounds 54-64 have been designed, synthesised and evaluated against behavioural alterations using step down passive avoidance protocol at a dose of 0.5 mg/kg with Donepezil (1) as the reference standard. All the synthesised compounds were evaluated for their in vitro acetylcholinesterase (AChE) inhibition at five different concentrations using mice brain homogenate as the source of the enzyme...
November 22, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/29184375/biochemical-analysis-of-some-serum-trace-elements-in-donkeys-and-horses-in-eastern-region-of-kingdom-of-saudi-arabia
#14
Turke Shawaf, Faisal Almathen, Ahmad Meligy, Wael El-Deeb, Shahab Al-Bulushi
Aim: Little is known about the serum levels of trace elements in donkeys and horses in Saudi Arabia. This study aimed to investigate the levels of some trace elements in these two species in the eastern region of Saudi Arabia and to compare the obtained results with the reference values. Materials and Methods: Seventeen Arabian horses and twenty eight Hassawi donkeys were randomly selected for this study. All of the studied healthy animals were kept under a uniform feeding protocol without any minerals supplementations...
October 2017: Veterinary World
https://www.readbyqxmd.com/read/29181269/diagnostic-test-accuracy-study-of-18f-sodium-fluoride-pet-ct-99mtc-labelled-diphosphonate-spect-ct-and-planar-bone-scintigraphy-for-diagnosis-of-bone-metastases-in-newly-diagnosed-high-risk-prostate-cancer
#15
Randi F Fonager, Helle D Zacho, Niels C Langkilde, Joan Fledelius, June A Ejlersen, Christian Haarmark, Helle W Hendel, Mine Benedicte Lange, Mads R Jochumsen, Jesper C Mortensen, Lars J Petersen
The aim of this study was to prospectively compare planar, bone scan (BS) versus SPECT/CT and NaF PET/CT in detecting bone metastases in prostate cancer. Thirty-seven consecutive, newly diagnosed, prostate cancer patients with prostate specific antigen (PSA) levels ≥ 50 ng/mL and who were considered eligible for androgen-deprivation therapy (ADT) were included in this study. BS, SPECT/CT, and NaF PET/CT, were performed prior to treatment and were repeated after six months of ADT. Baseline images from each index test were independently read by two experienced readers...
2017: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29177576/variation-in-biochemical-constituents-and-master-elements-in-common-seaweeds-from-alexandria-coast-egypt-with-special-reference-to-their-antioxidant-activity-and-potential-food-uses-prospective-equations
#16
Mona M Ismail, Gehan M El Zokm, Abeer A M El-Sayed
Biochemical constituents and master elements (Pb, Cr, Cd, Fe, Cu, Zn, Hg, B, Al, SO42-, Na, K, Li, Ca, Mg, and F) were investigated in six different seaweed species from Abu Qir Bay in the Egyptian Mediterranean Sea coast. The moisture level ranged from 30.26% in Corallina mediterranea to 77.57% in Padina boryana. On dry weight basis, the ash contents varied from 25.53% in Jania rubens to 88.84% in Sargassum wightii. The protein contents fluctuated from 8.26% in S. wightii to 28.01% in J. rubens. Enteromorpha linza showed the highest lipids (4...
November 25, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29159585/kfoa-the-udp-glucose-4-epimerase-of-escherichia-coli-strain-o5-k4-h4-shows-preference-for-acetylated-substrates
#17
Hao-Miao Zhu, Bin Sun, Yi-Jun Li, Dan-Hua Meng, Shuang Zheng, Ting-Ting Wang, Feng-Shan Wang, Ju-Zheng Sheng
Capsule of Escherichia coli O5:K4:H4 is formed of a chondroitin-repeat disaccharide unit of glucuronic acid (GlcA)-N-acetylgalactosamine (GalNAc). This polysaccharide, commonly referred to as K4CP, is a potentially important source of precursors for chemoenzymatic or bioengineering synthesis of chondroitin sulfate. KfoA, encoded by a gene from region 2 of the K4 capsular gene cluster, shows high homology to the UDP-glucose-4-epimerase (GalE) from E. coli. KfoA is reputed to be responsible for uridine 5'-diphosphate-N-acetylgalactosamine (UDP-GalNAc) supply for K4CP biosynthesis in vivo, but it has not been biochemically characterized...
November 20, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29153517/rapid-species-and-subspecies-specific-level-classification-and-identification-of-lactobacillus-casei-group-members-using-maldi-biotyper-combined-with-clinprotools
#18
Chien-Hsun Huang, Lina Huang
Using common taxonomic methods such as 16S rDNA sequencing and physiological and biochemical analysis to identify members of the Lactobacillus casei group (LCG) is time-consuming, expensive and inaccurate. In this study, we applied matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) to rapid discriminate LCG strains by creating an analytical in-house database (IHDB) and to develop a classification model for subspecies-level differentiation based on MS biomarkers using ClinProTools bioinformatics software (Bruker Daltonics, Billerica, MA)...
November 15, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29134929/mucilaginibacter-panaciglaebae-sp-nov-isolated-from-soil-of-a-ginseng-field
#19
Soon Youl Lee, Muhammad Zubair Siddiqi, Sang Yong Kim, Hong Shan Yu, Jae Hak Lee, Wan-Taek Im
A Gram-reaction-negative, strictly aerobic, non-motile and rod-shaped bacterium, designated strain BXN5-31(T), was isolated from soil of a ginseng field, and its taxonomic position was investigated using a polyphasic approach. Strain BXN5-31(T) grew at 18-37 °C and at pH 6.0-8.0 on R2A medium. Based on 16S rRNA gene sequence similarity, strain BXN5-31(T) was shown to belong to the genus Mucilaginibacter and was closely related to Mucilaginibactersoyangensis HME6664(T), Mucilaginibacterximonensis XM-003(T) and Mucilaginibacterpuniceus WS71(T)...
November 14, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29126424/salivary-ph-calcium-phosphorus-and-selected-enzymes-in-healthy-dogs-a-pilot-study
#20
Ilaria Iacopetti, Anna Perazzi, Tamara Badon, Silvia Bedin, Barbara Contiero, Rebecca Ricci
BACKGROUND: Saliva in dogs, as in humans, is a complex fluid secreted by different salivary glands in the oral cavity to protect the oral mucosa and teeth. The use of saliva as a substitute for blood in diagnosing and prognosticating disease in humans is widely accepted. Salivary biochemistry has also been used as a marker for periodontal disease in humans. No studies have as yet investigated the relation between salivary biochemistry and periodontal disease in dogs, however; neither has the salivary composition of healthy dogs with no oral disease been assessed...
November 10, 2017: BMC Veterinary Research
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