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Maxillofacial reconstruction

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https://www.readbyqxmd.com/read/27890229/maxillofacial-defects-and-the-use-of-growth-factors
#1
REVIEW
Alan S Herford, Meagan Miller, Fabrizio Signorino
The development and increase in knowledge of the benefits and applications of growth factors in craniofacial reconstruction adds a novel tool in the reconstructive surgeon's armamentarium. The use of growth factors varies according to presentation. Growth factors help to promote healing, angiogenesis, and formation of bone of improved quality and quantity. Growth factors used with stem cells and scaffolds provide a solution or alternative to discomfort created by donor autograft sites. The application and results of these growth factors are displayed in various examples of maxillofacial defects in this article, including reconstruction of a premaxillary cleft and of maxillary augmentation...
February 2017: Oral and Maxillofacial Surgery Clinics of North America
https://www.readbyqxmd.com/read/27890228/tissue-engineered-prevascularized-bone-and-soft-tissue-flaps
#2
REVIEW
F Kurtis Kasper, James Melville, Jonathan Shum, Mark Wong, Simon Young
The complex shapes of skeletal components of the craniofacial region combined with the prominence of the face and paucity of overlying soft tissue create significant challenges for the reconstructive surgeon. The in vivo bioreactor strategy is a promising alternative to microvascular surgical techniques that combines tissue engineering principles with microvascular reconstructive techniques to create patient-specific, prevascularized bone flaps for reconstruction of complex maxillofacial defects. This article discusses the use of traditional vascularized bone flaps; preclinical studies using the in vivo bioreactor approach; case reports that have attempted this novel technique; and future challenges and considerations in the development of patient-specific, prevascularized bone flaps for maxillofacial reconstruction...
February 2017: Oral and Maxillofacial Surgery Clinics of North America
https://www.readbyqxmd.com/read/27882508/regional-early-development-and-eruption-of-permanent-teeth-case-report
#3
A M Al Mullahi, A Bakathir, S Al Jahdhami
BACKGROUND: Early development and eruption of permanent teeth are rarely reported in scientific literature. Early eruption of permanent teeth has been reported to occur due to local factors such as trauma or dental abscesses in primary teeth, and in systemic conditions. Congenital diffuse infiltrating facial lipomatosis (CDIFL) is a rare condition that belongs to a group of lipomatosis tumours. In this disorder, the mature adipocytes invade adjacent soft and hard tissues in the facial region...
November 23, 2016: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/27871286/maxillary-calcifying-epithelial-odontogenic-tumor-with-sinus-and-buccal-vestibule-extension-a-case-report-and-immunohistochemical-study
#4
Cristina Munteanu, Daniel Pirici, Alex Emilian Stepan, Adrian Camen, Claudiu Margaritescu
BACKGROUND: Calcifying epithelial odontogenic tumor (CEOT) is a rare benign neoplasia, locally aggressive, that tends to invade bone and adjacent soft tissues. This case report describes the thirteenth known case of CEOT with maxillary sinus extension and the second one that also involves the buccal vestibule mucosa with peculiar histopathological and immunohistochemical data. CASE PRESENTATION: Here we report the case of a 45-year-old female with a CEOT diagnosed and treated at the Oral & Maxillofacial Surgery Department, County Clinical Emergency Hospital of Craiova, Romania...
November 21, 2016: Diagnostic Pathology
https://www.readbyqxmd.com/read/27860210/limitation-of-the-antibiotic-eluting-bone-graft-substitute-an-example-of-gentamycin-impregnated-calcium-sulfate
#5
Chang-Chin Wu, Yang-Kai Huang, Wei-Jen Chang, Yun-Ching Wu, Chen-Chie Wang, Kai-Chiang Yang
Patients with inadequate volume of alveolar processes or bone defects commonly require graft substitutes in oral, maxillofacial or orthopedic surgery. Ridge augmentation and reconstruction of facial bony defects with bone graft materials achieve better outcomes in functional and aesthetic rehabilitation. The injectable calcium sulfate filler is used widely in intra-operative applications. Calcium sulfate bone filler has been shown to upregulate bone formation-related mRNA genes in vitro and improve osseointegration in vivo...
November 18, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/27858078/-clinical-study-of-facial-artery-island-flap-for-reconstruction-of-oral-and-maxillofacial-tissue-defects-in-96-consecutive-patients
#6
Wei Wang, Chao-Bin Pan, Yu-Feng Chi, Pei Wang, Xi-Tao Tan, Yong Chen
PURPOSE: To evaluate the clinical effect of facial artery island flap for immediate reconstruction of oral and maxillofacial defects. METHODS: From March 2007 to August 2015, the clinical data of 96 patients with facial artery island flap for reconstruction of oral and maxillofacial defects were recorded and analyzed, including 46 patients undergoing anterograde facial artery flap and 50 patients undergoing reversed facial artery flap. The short-term and long-term clinical effect, including receipt site, flap survival, facial appearance and function, and postoperative complications were investigated. RESULTS: The overall success rate for facial artery island flap was 96...
August 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/27847734/surgical-implications-of-anatomical-variation-in-anterolateral-thigh-flaps-for-the-reconstruction-of-oral-and-maxillofacial-soft-tissue-defects-focus-on-perforators-and-pedicles
#7
Ji-Wan Kim, Dong-Young Kim, Kang-Min Ahn, Jee-Ho Lee
OBJECTIVES: To gain information on anatomical variation in anterolateral thigh (ALT) flaps in a series of clinical cases, with special focus on perforators and pedicles, for potential use in reconstruction of oral and maxillofacial soft tissue defects. MATERIALS AND METHODS: Eight patients who underwent microvascular reconstructive surgery with ALT free flaps after ablative surgery for oral cancer were included. The number of perforators included in cutaneous flaps, location of perforators (septocutaneous or musculocutaneous), and the course of vascular pedicles were intraoperatively investigated...
October 2016: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/27836445/-masticatory-system-and-maxillofacial-prosthesis-from-pathology-to-function-recovering
#8
S Vo Quang, J Dichamp
Maxillofacial prosthesis (MFP) can be defined as the art and science of esthetic and functional reconstruction of the facial bones, art because it uses hand-crafted and empirical rules, science because of its technical rigorism and its integration in medicine. MFP aims to multidisciplinary rehabilitate patients presenting with cutaneous and underlying structures defects, It also allows for functional speech and swallowing rehabilitation related to temporo-mandibular joint disorders. Whatever the origin, (traumatic, infectious ortumoral), surgical treatment of these TMJ disorders is usually not indicated in first-line...
November 8, 2016: Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale
https://www.readbyqxmd.com/read/27833710/current-management-of-zygomaticomaxillary-complex-fractures-a-multidisciplinary-survey-and-literature-review
#9
Scott J Farber, Dennis C Nguyen, Gary B Skolnick, Albert S Woo, Kamlesh B Patel
Despite the prevalence of zygomaticomaxillary complex (ZMC) fractures, there is no consensus regarding the best approach to management. The aim of this study is to determine differences in ZMC fracture treatment among various surgical specialties. A survey was conducted regarding treatment of patients with different ZMC fractures that included a minimally displaced fracture (Case 1), a displaced fracture without diplopia (Case 2), a displaced fracture with diplopia (Case 3), and a complex comminuted fracture (Case 4)...
November 2016: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/27833693/e-cigarette-blast-injury-complex-facial-fractures-and-pneumocephalus
#10
Benjamin A Archambeau, Stephanie Young, Carol Lee, Troy Pennington, Christopher Vanderbeek, Dan Miulli, John Culhane, Michael Neeki
Electronic cigarettes (also known as e-cigarettes or e-cigs) are becoming a popular method of recreational nicotine use over recent years. The growth of new brands and devices has been outpacing the FDA's ability to regulate them. As a result, some of these devices fail without warning, most likely from malfunction of the lithium-ion batteries that are in close proximity to volatile compounds within the device. Failures have occurred during both use and storage of the devices or their components. The subsequent injuries from several of these events, including full thickness burns requiring grafting and blast injuries, have been observed at Arrowhead Regional Medical Center, a regional trauma and burn center in southern California...
November 2016: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27833286/diagnostic-tools-in-maxillofacial-fractures-is-there-really-a-need-of-three-dimensional-computed-tomography
#11
Sheerin Shah, Sanjeev K Uppal, Rajinder K Mittal, Ramneesh Garg, Kavita Saggar, Rishi Dhawan
INTRODUCTION: Because of its functional and cosmetic importance, facial injuries, especially bony fractures are clinically very significant. Missed and maltreated fractures might result in malocclusion and disfigurement of the face, thus making accurate diagnosis of the fracture very essential. In earlier times, conventional radiography along with clinical examination played a major role in diagnosis of maxillofacial fractures. However, it was noted that the overlapping nature of bones and the inability to visualise soft tissue swelling and fracture displacement, especially in face, makes radiography less reliable and useful...
May 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/27826386/postoperative-irradiation-after-implant-placement-a-pilot-study-for-prosthetic-reconstruction
#12
Re-Mee Doh, Sungtae Kim, Ki Chang Keum, Jun Won Kim, June-Sung Shim, Han-Sung Jung, Kyeong-Mee Park, Moon-Kyu Chung
PURPOSE: On maxillofacial tumor patients, oral implant placement prior to postoperative radiotherapy can shorten the period of prosthetic reconstruction. There is still lack of research on effects of post-implant radiotherapy such as healing process or loading time, which is important for prosthodontic treatment planning. Therefore, this study evaluated the effects of post-implant local irradiation on the osseointegration of implants during different healing stages. MATERIALS AND METHODS: Custom-made implants were placed bilaterally on maxillary posterior edentulous area 4 weeks after extraction of the maxillary first molars in Forty-eight Sprague-Dawley rats...
October 2016: Journal of Advanced Prosthodontics
https://www.readbyqxmd.com/read/27823937/orbital-blowout-fractures-a-novel-computed-tomographic-measurement-that-can-predict-the-likelihood-of-surgical-management
#13
Tamer N Mansour, Megan Rudolph, Derek Brown, Natalie Mansour, M Reza Taheri
OBJECTIVE: The purpose of this study is to identify an accurate and reliable computed tomographic (CT) measurement that can identify those patients presenting to the emergency department (ED) with orbital floor fracture (BOF) who require surgical repair to prevent ensuing visually debilitating diplopia and/or enophthalmos. METHODS: In this retrospective institutional review board-approved study, we reviewed 99 patients older than 18 years with orbital fractures treated in a level I trauma center from 2011 through 2015...
October 14, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27810548/immediate-transoral-allogeneic-bone-grafting-for-large-mandibular-defects-less-morbidity-more-bone-a-paradigm-in-benign-tumor-mandibular-reconstruction
#14
James C Melville, Nader N Nassari, Issa A Hanna, Jonathan W Shum, Mark E Wong, Simon Young
PURPOSE: Reconstruction of hard tissue continuity defects caused by ablative tumor surgery has been traditionally reconstructed with autogenous bone grafts or microvascular free flaps. Although results have been predictable from these 2 methods of reconstruction, the morbidity associated with bone harvest is quite serious for the patient. Predictable results have been obtained with using a combination of 100% cadaver bone, bone marrow aspirate concentrate (BMAC), and recombinant human bone morphogenic protein in immediate reconstruction for benign tumor extirpations through the extraoral approach...
October 6, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27806758/-biological-evaluation-of-three-dimensional-printed-co-poly-lactic-acid-glycolic-acid-tri-calcium-phosphate-scaffold-for-bone-reconstruction
#15
S Y Li, M Zhou, Y X Lai, Y M Geng, S S Cao, X M Chen
Objective: To biologically evaluate the three-dimensional(3D) printed co-poly lactic acid/glycolic acid/tri-calcium phosphate(PLGA/TCP) scaffold which could be used for repairing oral and maxillofacial bone defects, and to provide experimental evidence for its further research and clinical application. Methods: PLGA/TCP scaffolds were fabricated using low temperature rapid prototyping technique. Micro-CT and scanning electron microscope(SEM) were used to characterize the surface morphology. MC3T3-E1 cells were seeded onto the scaffold and stained with the rhodamine phalloidin and calcein acetomethoxy...
November 9, 2016: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/27790591/prosthodontic-rehabilitation-of-accidental-maxillofacial-gunshot-injury-using-dental-implants-a-five-year-follow-up-clinical-report
#16
Vinod Balla, Angleena Y Daniel, Nirmal Kurian
Gunshot injuries to the face can have serious aesthetic, functional, and psychological consequences. The incapacitating nature of maxillofacial defects makes reconstruction of the maxilla and mandible challenging, owing to multiple surgeries and extensive rehabilitation phase. Outcome of prosthodontic treatment is one of the important parameters by which a patient measures the success of rehabilitation. A 5-year follow-up of comprehensive surgical and prosthodontic reconstruction of a gunshot injury using dental implants is described...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27786546/ct-of-facial-fracture-fixation-an-experimental-study-of-artifact-reducing-methods
#17
Elina M Peltola, Teemu Mäkelä, Ville Haapamäki, Anni Suomalainen, Junnu Leikola, Seppo K Koskinen, Mika Kortesniemi, Mika P Koivikko
OBJECTIVES: This study aimed to determine the optimal postoperative CT imaging method that enables best visualization of facial bony structures in the vicinity of osteosynthesis material. METHODS: Conducted at (blinded 1), this study relied on scanning a phantom with cone-beam computed tomography (CBCT), a 64-slice computed tomography (CT) and a high-definition multi-slice CT with dual-energy scan (providing monochromatic images of 70, 100, 120 and 140 keV energy levels) and iterative reconstruction (IR) methods...
October 27, 2016: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/27770969/a-current-overview-of-materials-and-strategies-for-potential-use-in-maxillofacial-tissue-regeneration
#18
Hossein E Jazayeri, Mohammadreza Tahriri, Mehdi Razavi, Kimia Khoshroo, Farahnaz Fahimipour, Erfan Dashtimoghadam, Luis Almeida, Lobat Tayebi
Tissue regeneration is rapidly evolving to treat anomalies in the entire human body. The production of biodegradable, customizable scaffolds to achieve this clinical aim is dependent on the interdisciplinary collaboration among clinicians, bioengineers and materials scientists. While bone grafts and varying reconstructive procedures have been traditionally used for maxillofacial defects, the goal of this review is to provide insight on all materials involved in the progressing utilization of the tissue engineering approach to yield successful treatment outcomes for both hard and soft tissues...
January 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27770634/repair-of-bone-defects-in%C3%A2-vivo-using-tissue-engineered-hypertrophic-cartilage-grafts-produced-from-nasal-chondrocytes
#19
Katie Bardsley, Agnieska Kwarciak, Christine Freeman, Ian Brook, Paul Hatton, Aileen Crawford
The regeneration of large bone defects remains clinically challenging. The aim of our study was to use a rat model to use nasal chondrocytes to engineer a hypertrophic cartilage tissue which could be remodelled into bone in vivo by endochondral ossification. Primary adult rat nasal chondrocytes were isolated from the nasal septum, the cell numbers expanded in monolayer culture and the cells cultured in vitro on polyglycolic acid scaffolds in chondrogenic medium for culture periods of 5-10 weeks. Hypertrophic differentiation was assessed by determining the temporal expression of key marker genes and proteins involved in hypertrophic cartilage formation...
October 11, 2016: Biomaterials
https://www.readbyqxmd.com/read/27752205/the-jugaad-technique-for-jaw-reconstruction-denture-based-inverse-planning
#20
Vinay V Kumar, P C Jacob, Vikram Kekatpure, Naveen Hedne, Felix P Koch, Moni A Kuriakose
AIM: The aim of this clinical paper is to introduce a technique to plan for functional maxillofacial reconstructions. MATERIALS AND METHODS: Preoperative dental casts were made of the patient and mock surgery performed on the casts. A fibula analogue was then placed in an ideal functional reconstruction position. New dentures were fabricated on the fibula analogue and drill holes for the placement of implants were placed through the denture. This denture formed as a guide to position the fibula transplant during surgery...
September 2016: Journal of Maxillofacial and Oral Surgery
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