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Motor control infant

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https://www.readbyqxmd.com/read/29648420/prenatal-exposure-to-ddt-and-pyrethroids-for-malaria-control-and-child-neurodevelopment-the-vhembe-cohort-south-africa
#1
Brenda Eskenazi, Sookee An, Stephen A Rauch, Eric S Coker, Angelina Maphula, Muvhulawa Obida, Madelein Crause, Katherine R Kogut, Riana Bornman, Jonathan Chevrier
BACKGROUND: Although indoor residual spraying (IRS) with dichlorodiphenyltrichloroethane (DDT) and pyrethroids effectively controls malaria, it potentially increases human exposure to these insecticides. Previous studies suggest that prenatal exposure to these insecticides may impact human neurodevelopment. OBJECTIVES: We aimed to estimate the effects of maternal insecticide exposure and neurodevelopment of toddlers living in a malaria-endemic region currently using IRS...
April 6, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29643070/neurobehavioral-outcomes-11-years-after-neonatal-caffeine-therapy-for-apnea-of-prematurity
#2
Ines M Mürner-Lavanchy, Lex W Doyle, Barbara Schmidt, Robin S Roberts, Elizabeth V Asztalos, Lorrie Costantini, Peter G Davis, Deborah Dewey, Judy D'Ilario, Ruth E Grunau, Diane Moddemann, Harvey Nelson, Arne Ohlsson, Alfonso Solimano, Win Tin, Peter J Anderson
BACKGROUND AND OBJECTIVES: Caffeine is effective in the treatment of apnea of prematurity. Although caffeine therapy has a benefit on gross motor skills in school-aged children, effects on neurobehavioral outcomes are not fully understood. We aimed to investigate effects of neonatal caffeine therapy in very low birth weight (500-1250 g) infants on neurobehavioral outcomes in 11-year-old participants of the Caffeine for Apnea of Prematurity trial. METHODS: Thirteen academic hospitals in Canada, Australia, Great Britain, and Sweden participated in this part of the 11-year follow-up of the double-blind, randomized, placebo-controlled trial...
April 11, 2018: Pediatrics
https://www.readbyqxmd.com/read/29606022/associations-between-neural-injury-markers-of-intrauterine-growth-restricted-infants-and-neurodevelopment-at-2-years-of-age
#3
E Mazarico, E Llurba, L Cabero, O Sánchez, A Valls, A Martin-Ancel, D Cardenas, M D Gómez Roig
OBJECTIVES: The aim of this study was to evaluate the relationships between brain injury biomarkers in intrauterine growth-restricted (IUGR) infants (S100B and neuron-specific enolase (NSE)) and neurodevelopment at 2 years of age. METHODS: This prospective case-control study was a cooperative effort among Spanish Maternal and Child Health Network (Retic SAMID) hospitals. At inclusion, biometry for estimated fetal weight and feto-placental Doppler variables were measured for each infant...
March 31, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29576227/effects-of-early-comprehensive-interventions-on-child-neurodevelopment-in-poor-rural-areas-of-china-a-moderated-mediation-analysis
#4
S Liu, Z Wang, C Zhao, X Huang, X Liang, X Wang, S Lu, R W Scherpbier
OBJECTIVES: To examine the effects of early comprehensive interventions on home environment and child neurodevelopment among children younger than 3 years in poor rural areas of China, as well as the underlying mediating and moderating mechanisms. STUDY DESIGN: Non-randomized intervention study was conducted among 216 children aged 0-3 years in Shanxi province of China. Based on a 2 × 2 factor design, children in Lin and Fenxi County were assigned to an intervention group with duration less than 1 year (n = 26) or an intervention group with duration longer than 1 year (n = 82), while children in Fangshan County served as a control group with duration less than 1 year (n = 30) or a control group with duration longer than 1 year (n = 78)...
March 22, 2018: Public Health
https://www.readbyqxmd.com/read/29569536/introduction-of-iodised-salt-benefits-infants-mental-development-in-a-community-based-cluster-randomised-effectiveness-trial-in-ethiopia
#5
Karim Bougma, Frances E Aboud, Tizita M Lemma, Edward A Frongillo, Grace S Marquis
The effectiveness of salt iodisation in improving the mental development of young children has not been assessed. We implemented a community-based cluster-randomised effectiveness trial in sixty randomly selected districts in the Amhara region of Ethiopia. We randomly allocated each district to treatment and randomly selected one of its villages. In parallel to national salt iodisation efforts, iodised salt was brought early into the markets of the thirty intervention villages before it became widely available in the thirty control villages 4-6 months later...
April 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29567814/motor-impairment-trends-in-extremely-preterm-children-1991-2005
#6
Alicia J Spittle, Kate Cameron, Lex W Doyle, Jeanie L Cheong
BACKGROUND: There are increasing numbers of surviving children who were born extremely preterm (EP; gestational age <28 weeks) or extremely low birth weight (ELBW; birth weight <1000 g). Our objective in this study was to compare the rates of motor impairment at 8 years of age between 3 cohorts of EP and/or ELBW and term-born children to establish if motor impairment rates are changing over time. METHODS: All children born EP and/or ELBW in the calendar years of 1991-1992, 1997, and 2005 in Victoria, Australia, were recruited at birth...
March 22, 2018: Pediatrics
https://www.readbyqxmd.com/read/29503269/neurodevelopmental-status-of-children-aged-6-30-months-with-severe-acute-malnutrition
#7
Deepak Dwivedi, Surendra Singh, Jyoti Singh, Naresh Bajaj, Harendra Pratap Singh
OBJECTIVE: This cross sectional study was done to assess the developmental status in children (6-30 mo old) with severe acute malutrition (SAM). METHODS: Study subjects were enrolled from children in SAM therapeutic unit, and controls were selected from well-baby clinic of the institute. Neurodevelopment of both groups was assessed using the Developmental assessment scale of Indian infants (DASII). Developmental quotient (DQ) ≤70 was considered delayed. RESULTS: Mean (SE) motor DQ 59...
February 15, 2018: Indian Pediatrics
https://www.readbyqxmd.com/read/29501346/the-clinical-characteristics-and-neurodevelopmental-outcome-of-preterm-infants-with-persistent-periventricular-echogenicity
#8
Mi Hye Bae, Hyun Ji Jang, Na Rae Lee, Young Mi Han, Shin Yun Byun, Kyung Hee Park
PURPOSE: Periventricular echogenicity (PVE) presents as diffuse echo dense lesions of the periventricular white matter on cranial ultrasonography. Beyond two weeks of life, it is considered as prolonged or persistent PVE. The aim of our study was to investigate the clinical characteristics of preterm infants with persistent PVE beyond 2 weeks after birth and to determine whether these infants had an adverse neurodevelopmental outcome. METHODS: The medical records of preterm infants who were born at < 34 weeks of gestation and admitted to Pusan National University Hospital between 2009 and 2014 were reviewed...
February 13, 2018: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29497771/cerebral-blood-flow-following-hybrid-stage-i-palliation-in-infants-with-hypoplastic-left-heart-syndrome
#9
Sharon L Cheatham, Joanne L Chisolm, Nicole O'Brien
Hypoplastic left heart syndrome (HLHS) palliation may result in altered cerebral blood flow with subsequent neurodevelopmental implications. The purpose of the study was to assess blood flow in the middle cerebral artery (MCA) and investigate the relationship with early neurodevelopmental outcomes in infants with HLHS after hybrid stage I. Transcranial Doppler (TCD) was performed to obtain peak systolic, end-diastolic, and mean velocities, as well as pulsatility index of the MCA in infants with HLHS (n = 18) at baseline and at 2, 4, and 6 months of age...
March 2, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29489662/motor-development-delay-in-offspring-is-associated-with-prenatal-telbivudine-exposure
#10
Chengliang Zhou, Ying Yu, Qian Yang, Huihui Wang, Min Hou, Li Jin, Fanghong Zhang, Jiangzhong Sheng, Mingfang Miao, Xiaofu Yang, He-Feng Huang
Telbivudine is an orally nucleoside analog with potent and specific antihepatitis B virus (HBV) activity, and it has been reported to block mother-to-infant transmission. However, few studies have focused on the safety of prenatal exposure for offspring development.This is a prospective noninterventional study. Participants were enrolled during delivery through the Women's Hospital of Zhejiang University School of Medicine between January 2012 and September 2013. Neonate's umbilical cord arterial blood (UCAB) was collected after delivery...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29470360/oral-supplementation-with-bovine-colostrum-prevents-septic-shock-and-brain-barrier-disruption-during-bloodstream-infection-in-preterm-newborn-pigs
#11
Anders Brunse, Päivi Worsøe, Susanne Elisabeth Pors, Kerstin Skovgaard, Per Torp Sangild
Preterm infants have increased risk of neonatal sepsis, potentially inducing brain injury, and they may benefit from early initiation of enteral milk feeding. Using preterm pigs as models, we hypothesized that early provision of bovine colostrum to parentally nourished newborns protects against sepsis and neuroinflammation during bloodstream infection. Preterm newborn pigs were administered 10 CFU/kg of intra-arterial Staphylococcus epidermidis (SE, an opportunistic pathogen often causing sepsis in preterm infants), followed by administration of total parenteral nutrition (TPN, SE + TPN, n = 15) or oral provision of bovine colostrum with supplementary parenteral nutrition (SE + COL, n = 14), and compared with uninfected, TPN-nourished controls (CON + TPN, n = 11)...
February 21, 2018: Shock
https://www.readbyqxmd.com/read/29468770/pessary-for-prevention-of-preterm-birth-in-twin-pregnancy-with-short-cervix-3-year-follow-up-study
#12
J van 't Hooft, J H van der Lee, B C Opmeer, A G van Wassenaer-Leemhuis, A L van Baar, D J Bekedam, L J P Steenis, S Liem, E Schuit, C Cuijpers, E Bleeker, M E Vinke, N Simons, I M de Graaf, B W J Mol, C van de Beek
OBJECTIVE: A recent randomized clinical trial (ProTWIN) showed that a cervical pessary prevented preterm birth and improved neonatal outcome in women with multiple pregnancy and cervical length (CL) < 38 mm. In this follow-up study, the long-term developmental outcome of these children was evaluated at 3 years' corrected age. METHODS: This was a follow-up study of ProTWIN, a multicenter trial conducted between 2009 and 2012 in which asymptomatic women with a multiple pregnancy were randomized to placement of a cervical pessary or no intervention...
February 22, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29463142/levonorgestrel-emergency-contraceptive-pills-use-during-breastfeeding-effect-on-infants-health-and-development
#13
Omar M Shaaban, Ahmed M Abbas, Hanaa R Mahmoud, Entsar M Yones, Ahmed Mahmoud, Mahmoud S Zakherah
OBJECTIVE: The current study aims to evaluate the effect of the use of single packet of levonorgestrel emergency contraceptive pills (LNG-ECPs) during breastfeeding on the health and development of the nursing infant. MATERIALS AND METHODS: The current study was an ancillary observational cohort study carried out in a university hospital. We counseled all women delivered and planning birth-space and breastfeed for at least 1 year for participation during postpartum hospital stay...
February 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29457986/effect-of-oral-stimulation-on-feeding-performance-and-weight-gain-in-preterm-neonates-a-randomised-controlled-trial
#14
Pareshkumar A Thakkar, H R Rohit, Rashmi Ranjan Das, Ukti P Thakkar, Amitabh Singh
Background In preterm infants, oral stimulation enhances muscle tone and movement which facilitates normal oral motor developmental patterns improving oral feeding performance. Aim To study the effects on feeding performance, transition to independent oral feeding, weight gain and length of hospital stay of an oral stimulation programme in preterm neonates. Study design This randomised controlled trial was conducted in a tertiary care teaching hospital over a period of 10 months. Altogether, 102 preterm neonates (30-34 weeks gestation) were randomised into the intervention group (oro-motor stimulation for 5 min twice a day, n = 51) or the control group (routine care only, n = 51)...
February 19, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/29455866/cognition-action-trade-offs-reflect-organization-of-attention-in-infancy
#15
Sarah E Berger, Regina T Harbourne, Melissa N Horger
This chapter discusses what cognition-action trade-offs in infancy reveal about the organization and developmental trajectory of attention. We focus on internal attention because this aspect is most relevant to the immediate concerns of infancy, such as fluctuating levels of expertise, balancing multiple taxing skills simultaneously, learning how to control attention under variable conditions, and coordinating distinct psychological domains. Cognition-action trade-offs observed across the life span include perseveration during skill emergence, errors and inefficient strategies during decision making, and the allocation of resources when attention is taxed...
2018: Advances in Child Development and Behavior
https://www.readbyqxmd.com/read/29454023/interaction-between-hypothermia-and-delayed-mesenchymal-stem-cell-therapy-in-neonatal-hypoxic-ischemic-brain-injury
#16
Josephine Herz, Christian Köster, Barbara S Reinboth, Mark Dzietko, Wiebke Hansen, Hemmen Sabir, Cindy van Velthoven, Ivo Bendix, Ursula Felderhoff-Müser
Acute hypothermia treatment (HT) is the only clinically established intervention following neonatal hypoxic-ischemic brain injury. However, almost half of all cooled infants still die or suffer from long-lasting neurological impairments. Regenerative therapies, such as mesenchymal stem cells (MSC) appear promising as adjuvant therapy. In the present study, we hypothesized that HT combined with delayed MSC therapy results in augmented protection, improving long-term neurological outcome. Postnatal day 9 (P9) C57BL/6 mice were exposed to hypoxia-ischemia followed by 4 hours HT...
February 14, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29445839/vocalization-as-a-novel-endpoint-of-atypical-attachment-behavior-in-2-3-7-8-tetrachlorodibenzo-p-dioxin-exposed-infant-mice
#17
Eiki Kimura, Chiharu Tohyama
Mammalian attachment behaviors, such as crying, are essential for infant survival by receiving food, protection, and warmth from caregivers. Ultrasonic vocalization (USV) of infant rodents functions to promote maternal proximity. Impaired USV emission has been reported in mouse models of autism spectrum disorder, suggesting that USV is associated with higher brain function. In utero and lactational dioxin exposure is known to induce higher brain function abnormalities in adulthood; however, whether perinatal dioxin exposure affects behavior during infancy is unclear...
February 14, 2018: Archives of Toxicology
https://www.readbyqxmd.com/read/29441034/reduced-mu-power-in-response-to-unusual-actions-is-context-dependent-in-1-year-olds
#18
Miriam Langeloh, David Buttelmann, Daniel Matthes, Susanne Grassmann, Sabina Pauen, Stefanie Hoehl
During social interactions infants predict and evaluate other people's actions. Previous behavioral research found that infants' imitation of others' actions depends on these evaluations and is context-dependent: 1-year-olds predominantly imitated an unusual action (turning on a lamp with one's forehead) when the model's hands were free compared to when the model's hands were occupied or restrained. In the present study, we adapted this behavioral paradigm to a neurophysiological study measuring infants' brain activity while observing usual and unusual actions via electroencephalography...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29429466/-recurrent-convulsion-and-pulmonary-infection-complicated-by-psychomotor-retardation-in-an-infant
#19
Juan Xiong, Jing Peng, Hao-Lin Duan, Chen Chen, Xiao-Le Wang, Shi-Meng Chen, Fei Yin
A 4-month-old girl developed convulsion in the neonatal period, which was focal motor seizures in the initial stage and later became spasm and tonic spasm. And the girl also had psychomotor retardation and recurrent pulmonary infection. Electroencephalography showed hypsarrhythmia, normal results were obtained from cranial magnetic resonance imaging, cerebrospinal fluid examination, and urine organic acid analysis, as well as the spectral analyses of blood ammonia, blood lactic acid, blood amino acids, and acylcarnitines...
February 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29429197/-early-childhood-development-and-risk-factors-in-rural-china-a-cohort-study
#20
Y Cui, J Q Gao, A Yue, L Tang, R F Luo, Rozelle Scott
Objective: To investigate the development status and risk factors of infants and toddlers in rural China. Methods: In this cohort study, 603 infants (6-12 months of age, Phase Ⅰ) in the rural areas of QinLing-Bashan (Qin-Ba) in Shaanxi were recruited in the control group that received no intervention from April 2013 to October 2015. Three follow-up visits were performed every six months (Phase Ⅱ(12-18 months of age), Phase Ⅲ (18-24 months of age) and Phase Ⅳ(24-30 months of age)). In all the 4 phases (Ⅰ-Ⅳ), general data of the children and the families were collected by questionnaires, early childhood growth and development were assessed by door to door visits, children's hemoglobin levels were determined by laboratory tests, and the cognitive and motor development screening was conducted by the Bayley Scales of Infant and Toddler Development...
February 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
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