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https://www.readbyqxmd.com/read/28449017/a-multifaceted-intervention-to-improve-primary-care-radiology-referral-quality-and-value-in-canterbury
#1
Kieran Holland, Graham McGeoch, Carolyn Gullery
AIMS: This article describes a seven-year multifaceted intervention leading to sustained improvement in primary care radiology referral quality and value in Canterbury, New Zealand, and discusses the transferability to other health systems. METHODS: Access criteria were developed with input from general practitioners and hospital-based specialists, and embedded in locally developed clinical pathways. A referral management service was created to streamline referral processes...
April 28, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28448938/choice-modeling-of-system-wide-or-large-scale-environmental-change-in-a-developing-country-context-lessons-from-the-para%C3%A3-ba-do-sul-river
#2
James R Kahn, William F Vásquez, Carlos Eduardo de Rezende
The Rio Paraiba do Sul is a highly polluted river in south central Brazil, that is contaminated by industrial, agricultural and municipal wastes, as well as being impacted by dams, water withdrawals and deforestation in the watershed. Since only very intensive and farreaching environmental policies could result in water quality improvements, valuing the restoration of the river presents many unique challenges. We develop a choice-modeling approach to valuation of the restoration of this river, with general tightening of environmental policy as the policy, and an increase in prices as the payment vehicle...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448885/development-and-validation-of-a-liquid-chromatographic-method-for-the-analysis-of-squaric-acid-dibutyl-ester-and-its-impurities
#3
Marwa F Mansour, Peixi Zhu, Ann Van Schepdael, Erwin Adams
A simple, fast and selective stability indicating liquid chromatographic method has been described for the simultaneous determination of squaric acid dibutyl ester and its impurities. The chromatographic separation was achieved on a C2 column (250mm×4.6mm i.d., 5μm) using a mobile phase consisting of 0.15% phosphoric acid - acetonitrile - methanol (30:60:10, v/v/v). Isocratic elution was performed at a flow rate of 1.0mLmin(-1). The analytes were detected by UV at 252nm. The method was validated according to the ICH guidelines and satisfactory results were obtained...
April 18, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28448859/evolution-of-the-methodological-quality-of-controlled-clinical-trials-for-myofascial-trigger-point-treatments-for-the-period-1978-2015-a-systematic-review
#4
Rahel Stoop, Ron Clijsen, Diego Leoni, Emiliano Soldini, Greta Castellini, Valentina Redaelli, Marco Barbero
BACKGROUND: The methodological quality of controlled clinical trials (CCTs) of physiotherapeutic treatment modalities for myofascial trigger points (MTrP) has not been investigated yet. OBJECTIVES: To detect the methodological quality of CCTs for physiotherapy treatments of MTrPs and demonstrating the possible increase over time. DESIGN: Systematic review. METHODS: A systematic search was conducted in two databases, Physiotherapy Evidence Database (PEDro) and Medicine Medical Literature Analysis and Retrieval System online (MEDLINE), using the same keywords and selection procedure corresponding to pre-defined inclusion criteria...
April 18, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28448777/effect-of-an-advanced-pharmacy-practice-experience-on-medication-therapy-management-services-in-a-centralized-retail-pharmacy-program
#5
Joseph P Vande Griend, Melissa Rodgers, Wesley Nuffer
BACKGROUND: Medication therapy management (MTM) delivery is increasingly important in managed care. Successful delivery positively affects patient health and improves Centers for Medicare & Medicaid Services star ratings, a measure of health plan quality. As MTM services continue to grow, there is an increased need for efficient and effective care models. The primary objectives of this project were to describe the delivery of MTM services by fourth-year Advanced Pharmacy Practice Experience (APPE) students in a centralized retail pharmacy system and to evaluate and quantify the clinical and financial contributions of the students...
May 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28448556/a-highly-specific-and-sensitive-massive-parallel-sequencer-based-test-for-somatic-mutations-in-non-small-cell-lung-cancer
#6
Yoshiaki Inoue, Jun Shiihara, Hitoshi Miyazawa, Hiromitsu Ohta, Megumi Higo, Yoshiaki Nagai, Kunihiko Kobayashi, Yasuo Saijo, Masanori Tsuchida, Mitsuo Nakayama, Koichi Hagiwara
Molecular targeting therapy for non-small cell lung cancer (NSCLC) has clarified the importance of mutation testing when selecting treatment regimens. As a result, multiple-gene mutation tests are urgently needed. We developed a next-generation sequencer (NGS)-based, multi-gene test named the MINtS for investigating driver mutations in both cytological specimens and snap-frozen tissue samples. The MINtS was used to investigate the EGFR, KRAS, BRAF genes from DNA, and the ERBB2, and the ALK, ROS1, and RET fusion genes from RNA...
2017: PloS One
https://www.readbyqxmd.com/read/28448453/working-memory-in-the-prefrontal-cortex
#7
REVIEW
Shintaro Funahashi
The prefrontal cortex participates in a variety of higher cognitive functions. The concept of working memory is now widely used to understand prefrontal functions. Neurophysiological studies have revealed that stimulus-selective delay-period activity is a neural correlate of the mechanism for temporarily maintaining information in working memory processes. The central executive, which is the master component of Baddeley's working memory model and is thought to be a function of the prefrontal cortex, controls the performance of other components by allocating a limited capacity of memory resource to each component based on its demand...
April 27, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28448451/time-aware-service-ranking-prediction-in-the-internet-of-things-environment
#8
Yuze Huang, Jiwei Huang, Bo Cheng, Shuqing He, Junliang Chen
With the rapid development of the Internet of things (IoT), building IoT systems with high quality of service (QoS) has become an urgent requirement in both academia and industry. During the procedures of building IoT systems, QoS-aware service selection is an important concern, which requires the ranking of a set of functionally similar services according to their QoS values. In reality, however, it is quite expensive and even impractical to evaluate all geographically-dispersed IoT services at a single client to obtain such a ranking...
April 27, 2017: Sensors
https://www.readbyqxmd.com/read/28448407/automated-attenuation-based-tube-potential-selection-of-the-lower-extremity-runoff-a-comparison-to-fixed-kilovolt-with-automated-tube-current-modulation
#9
Martin Beeres, Kang Juhee, Andreas M Bucher, Claudia Frellesen, Moritz Albrecht, Julian L Wichmann, Clara Park, Moritz Kaup, Jan Erik Scholtz, Thomas J Vogl, Tatjana Gruber-Rouh, Boris Bodelle
PURPOSE: The aim of this study was to evaluate the impact of automated attenuation-based tube potential selection (ATPS) on image quality and radiation dose exposure parameters at a computed tomography angiography (CTA) lower-extremity runoff. MATERIALS AND METHODS: Two hundred forty patients (156 men, 84 women) underwent CTA examinations of the lower-extremity runoff on a second-generation dual-source computed tomography system: 120 patients at a fixed tube potential of 120 kV and a tube current of 180 reference mAs, another 120 patients using automated ATPS...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28448331/a-nurse-directed-model-for-nitrous-oxide-use-during-labor
#10
Toni Pinyan, Kelly Curlee, Mellanie Keever, Kathleen M Baldwin
BACKGROUND: Nitrous oxide has a long history of use and has been well documented in the literature as a safe, effective, and inexpensive option for pain management in labor in other countries, but it is underused in the United States. LOCAL PROBLEM: Pain relief options for laboring women in rural community hospitals with a small perinatal service are limited due to lack of availability of in-house anesthesia coverage. METHOD: This quality improvement project involved development and implementation of a nurse-driven, self-administered, demand-flow nitrous oxide program as an option for pain relief for laboring women in a rural community hospital...
May 2017: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/28448302/qsen-institute-rn-bsn-task-force-white-paper-on-recommendation-for-systems-based-practice-competency
#11
Ann M Stalter, Janet M Phillips, Mary A Dolansky
The Quality and Safety Education for Nurses (QSEN) Institute RN-BSN Task Force presents a white paper on Recommendation for a Systems-based Practice Competency. The task force proposes a seventh QSEN competency, systems-based practice, to improve patient quality and safety. Recommendations to integrate systems-based practice into both education and practice settings, consistent with job descriptions and promotion criteria, involve a comprehensive continuing education program for nurses upon interview, orientation, residency programming, performance evaluation, and license renewal...
April 26, 2017: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/28448049/controlled-release-of-chlorine-dioxide-in-a-perforated-packaging-system-to-extend-the-storage-life-and-improve-the-safety-of-grape-tomatoes
#12
Xiuxiu Sun, Elizabeth Baldwin, Anne Plotto, Jan Narciso, Christopher Ference, Mark Ritenour, Ken Harrison, Joseph Gangemi, Jinhe Bai
A controlled-release chlorine dioxide (ClO2) pouch was developed by sealing a slurry form of ClO2 into semipermeable polymer film; the release properties of the pouch were monitored in containers with or without fruit. The pouch was affixed to the inside of a perforated clamshell containing grape tomatoes, and the effect on microbial population, firmness, and weight loss was evaluated during a 14 day storage period at 20 °C. Within 3 days, the ClO2 concentration in the clamshells reached 3.5 ppm and remained constant until day 10...
April 7, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28448040/determination-of-high-affinity-antibody-antigen-binding-kinetics-using-four-biosensor-platforms
#13
Danlin Yang, Ajit Singh, Helen Wu, Rachel Kroe-Barrett
Label-free optical biosensors are powerful tools in drug discovery for the characterization of biomolecular interactions. In this study, we describe the use of four routinely used biosensor platforms in our laboratory to evaluate the binding affinity and kinetics of ten high-affinity monoclonal antibodies (mAbs) against human proprotein convertase subtilisin kexin type 9 (PCSK9). While both Biacore T100 and ProteOn XPR36 are derived from the well-established Surface Plasmon Resonance (SPR) technology, the former has four flow cells connected by serial flow configuration, whereas the latter presents 36 reaction spots in parallel through an improvised 6 x 6 crisscross microfluidic channel configuration...
April 17, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28447862/high-reliability-microcontroller-nerve-stimulator-for-assistance-in-regional-anaesthesia-procedures
#14
Carlos A Ferri, Antonio A F Quevedo
In the last decades, the use of nerve stimulators to aid in regional anaesthesia has been shown to benefit the patient since it allows a better location of the nerve plexus, leading to correct positioning of the needle through which the anaesthetic is applied. However, most of the nerve stimulators available in the market for this purpose do not have the minimum recommended features for a good stimulator, and this can lead to risks to the patient. Thus, this study aims to develop an equipment, using embedded electronics, which meets all the characteristics, for a successful blockade...
April 27, 2017: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/28447852/pressure-ulcers-prevalence-in-the-acute-care-setting-a-systematic-review-2000-2015
#15
Ahmad Tubaishat, Panos Papanikolaou, Denis Anthony, Laila Habiballah
Little is known about the prevalence of pressure ulcer (PrU) in acute care settings. The aim of this study is to determine the prevalence rate of PrU in acute care settings and to assess the methodological quality of the reviewed publications. The Cumulative Index to Nursing and Allied Health Literature, British Nursing Index, MEDLINE, and Cochrane Database of Systematic Reviews were searched using the keywords pressure ulcer or decubitus ulcer or bed sore or pressure sore or pressure injury, with prevalence and acute care, for studies published between January 2000 and December 2015...
April 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/28447786/a-3d-mas-nmr-experiment-utilizing-through-space-15n-15n-correlations
#16
Kevin J Donovan, Robert Silvers, Sara Linse, Robert G Griffin
We demonstrate a novel 3D NNC magic angle spinning (MAS) NMR experiment that generates 15N- 15N internuclear contacts in protein systems using an optimized 15N- 15N proton assisted recoupling (PAR) mixing period and a 13C dimension for improved resolution. The optimized PAR condition permits the acquisition of high signal-to-noise 3D data that enables backbone chemical shift assignments using a strategy that is complementary to current schemes. The spectra can also provide distance constraints. The utility of the experiment is demonstrated on an M0Ab1-42 fibril sample that yields high-quality data that is readily assigned and interpreted...
April 27, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28447531/treatment-of-foot-varicose-veins-a-study-of-119-consecutive-patients
#17
Luiz Fernando Albernaz, Daiane Taís Schlindwein Albernaz, Fernanda Rita Machado Zignani, Yung-Wei Chi
Objective To analyze the outcomes of 119 (188 feet) patients undergoing foot varicose vein phlebectomy with and without sclerotherapy between 2013 and 2015. Methods Legs and feet were treated in one single procedure. Clinical and ultrasound assessments were carried out at 7, 30, and 90 days for visualization of the sapheno-femoral and sapheno-popliteal junctions and the deep vein system. Results Mean age was 50 ± 12 years (25-79 years); 67 patients were female (56.3%). Median venous clinical severity score was 4 (range 2-5) before and 1 (range 0-2) at 90 days ( p < 0...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28447491/mobile-communication-jacket-for-people-with-severe-speech-impairment
#18
Renée Lampe, Tobias Blumenstein, Varvara Turova, Ana Alves-Pinto
PURPOSE: Cerebral palsy is a movement disorder caused by damage to motor control areas of the developing brain during early childhood. Motor disorders can also affect the ability to produce clear speech and to communicate. The aim of this study was to develop and to test a prototype of an assistive tool with an embedded mobile communication device to support patients with severe speech impairments. METHODS: A prototype was developed by equipping a cycling jacket with a display, a small keyboard, a LED and an alarm system, all controlled by a microcontroller...
April 27, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28447243/the-longitudinal-association-of-relationship-quality-and-reoffending-among-first-time-juvenile-offenders-and-their-mothers
#19
Caitlin Cavanagh, Elizabeth Cauffman
To understand how youth desist from crime after their first arrest, it is necessary to investigate their primary support system: their parents. As such, this study examined the reciprocal effects of justice system contact on the mother-child dyad. Interviews with 317 mothers and their sons from Orange County, CA, Jefferson Parish, LA, and Philadelphia, PA were conducted semiannually over two and a half years. At the beginning of the study, the sons were first-time offenders aged 13-17 and mostly non-White (i...
April 26, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28447231/the-nutritional-interrelationship-between-the-growing-and-finishing-phases-in-crossbred-cattle-raised-in-a-tropical-system
#20
Ricardo Linhares Sampaio, Flávio Dutra de Resende, Ricardo Andrade Reis, Ivanna Moraes de Oliveira, Letícia Custódio, Rodolfo Maciel Fernandes, Raul Dirceu Pazdiora, Gustavo Rezende Siqueira
This study evaluated the nutritional interrelationship between the growing and finishing phases of crossbred cattle in determining their performance. One hundred and eight animals were used (8 months old, body weight [BW] 211 ± 20 kg). During the dry season, the animals received one of the following supplements: a mineral plus urea supplement (ad libitum, MSD), a protein supplement (1 g/kg BW per day, PR1), or a protein-energy supplement (5 g/kg BW per day, PE). During the rainy season, the animals received one of the following supplements: a mineral without urea supplement (ad libitum, MSR), a protein supplement (1 g/kg BW per day, PR2), or PE (5 g/kg BW per day)...
April 26, 2017: Tropical Animal Health and Production
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