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https://www.readbyqxmd.com/read/28436354/what-is-the-current-role-of-partial-nephrectomy-for-t2-tumors
#1
Bruno Nahar, Mark L Gonzalgo
INTRODUCTION: To review oncological and functional outcomes for partial nephrectomy in the setting of T2 tumors. MATERIALS AND METHODS: We performed a comprehensive literature review on partial nephrectomy for T2 tumors, focusing on major primary series reporting oncological and functional outcomes, as well as complication rates in the last 10 years. RESULTS: Recent series have reported comparable oncological outcomes between partial nephrectomy and radical nephrectomy for ≥ T2 tumors...
April 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28416104/multilocular-cystic-renal-cell-carcinoma-pathological-t-staging-makes-no-difference-to-favorable-outcomes-and-should-be-reclassified-bhatt-jr-jewett-ma-richard-po-kawaguchi-s-timilshina-n-evans-a-alibhai-s-finelli-a-j-urol-november-2016-196-5-1350-1355
#2
Oleksandr N Kryvenko
OBJECTIVE: We evaluated survival outcomes of cystic/multilocular cystic renal cell carcinomas in a long-term population-based study based on size and pathological tumor stage. MATERIALS AND METHODS: We, retrospectively, reviewed a provincial cancer registry of all histologically proven cases of multilocular cystic renal cancers treated surgically between 1995 and 2008. All cases of cystic necrosis were excluded from study. Primary end points were overall- and cancer-specific survival estimated using Kaplan-Meier curves...
April 13, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28411921/salvage-surgery-after-renal-mass-ablation
#3
REVIEW
Brian W Cross, Daniel C Parker, Michael S Cookson
Thermal ablative techniques represent treatment options for patients with small renal masses who are not candidates for surgery. The oncologic efficacy of ablation has not been compared in a randomized fashion with nephron-sparing surgery, and the urologist must be knowledgeable regarding the workup and treatment of patients with suspected residual or recurrent tumor following these therapies. Surveillance of patients with tumor recurrence after ablation may be indicated in select circumstances. When patients are deemed appropriate for salvage therapy, most undergo a repeat course of the same ablative modality...
May 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/28411919/complications-of-renal-surgery
#4
REVIEW
William T Berg, Jeffrey J Tomaszewski, Hailiu Yang, Anthony Corcoran
The incidence of the small renal mass continues to increase owing to the aging population and the ubiquity imaging. Most of these tumors are stage I tumors. Management strategies include surveillance, ablation, and extirpation. There is a wide body of literature favoring nephron-sparing approaches. Although nephron-sparing surgery may yield decreased long-term morbidity, it is not without its drawbacks, including a higher rate of complications. Urologists must be attuned to the complications of surgery and develop strategies to minimize risk...
May 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/28411909/current-trends-in-renal-surgery-and-observation-for-small-renal-masses
#5
REVIEW
Siri Drangsholt, William C Huang
There has been a rising incidence of small renal masses and concomitant downward stage migration. This has led to an evolution in the management of kidney cancer from radical nephrectomy to nephron-sparing treatment options including observation. The adoption of partial nephrectomy continues to increase but is still incomplete leading to significant disparities in the delivery of care throughout the country. Surgical excision remains the treatment of choice for small kidney cancers; however, ablative therapies and active surveillance are emerging as reasonable options for select patients...
May 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/28404588/adaptive-functional-change-of-the-contralateral-kidney-after-partial-nephrectomy
#6
Se Young Choi, Sangjun Yoo, Dalsan You, In Gab Jeong, Cheryn Song, Bumsik Hong, Jun Hyuk Hong, Hanjong Ahn, Choung-Soo Kim
Partial nephrectomy aims to maintain renal function by nephron sparing; however, functional changes in the contralateral kidney remain unknown. We evaluate the functional change in the contralateral kidney using a diethylene triamine penta-acetic acid (DTPA) renal scan and determine factors predicting contralateral kidney function after partial nephrectomy. A total of 699 patients underwent partial nephrectomy, with a DTPA scan before and after surgery to assess the separate function of each kidney. Patients were divided into three groups according to initial contralateral glomerular filtration rate (GFR; group 1: <30 ml/min/1...
April 12, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28399699/prognostic-and-discriminative-power-of-the-7th-tnm-classification-for-patients-with-surgically-treated-papillary-renal-cell-carcinoma-results-of-a-multi-institutional-validation-study-corona-subtype-project
#7
Matthias May, Cristian Surcel, Umberto Capitanio, Paolo Dell'Oglio, Tobias Klatte, Shahrokh Shariat, Thorsten Ecke, Ingmar Wolff, Daniel Vergho, Nina Wagener, Nina Huck, Sascha Pahernik, Stefan Zastrow, Manfred Wirth, Hendrik Borgmann, Axel Haferkamp, Mireia Musquera, Laura M Krabbe, Edwin Herrmann, Anna Scavuzzo, Cristian Mirvald, Georg Hutterer, Richard Zigeuner, Christian G Stief, Raphaela Waidelich, Luca Cindolo, Krystina Kalusova, Sabine D Brookman-May
OBJECTIVE: Studies on the prognostic reliability of the Union for International Cancer Control tumor, node, metastasis (TNM) staging system for renal cell carcinoma (RCC) predominantly focus on clear-cell RCC. Therefore, the aim of this study was to investigate whether the oncological prognosis of surgically treated papillary RCC (papRCC) patients is reliably given by the current TNM system, by analyzing the largest database reported to date. MATERIALS AND METHODS: Data on 2325 papRCC patients who underwent surgical treatment in 1984- 2015 were collated from 17 international centers (median follow-up 47 months)...
April 12, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28392835/bovine-serum-albumin-glutaraldehyde-bioglue-%C3%A2-tissue-adhesive-versus-standard-renorrhaphy-following-renal-mass-enucleation-a-retrospective-comparison
#8
Zaher Bahouth, Boaz Moskovitz, Sarel Halachmi, Ofer Nativ
BACKGROUND: To present the operative and post-operative comparison between patients who underwent tumor-bed closure with sutures compared with bovine serum albumin-glutaraldehyde (BioGlue(®)) tissue sealant only. METHODS: We retrospectively analyzed data from our ongoing database of 507 eligible patients who underwent open NSS nephron-sparing surgery in our department between January 1995 and May 2014. Patients had tumor-bed closure with sealant adhesive (255 patients) or standard suture technique (252 patients)...
March 2017: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/28387661/effectiveness-and-safety-of-laparoscopic-enucleation-combined-with-selective-arterial-embolization-for-renal-angiomyolipoma
#9
Dong Wang, Han-Zhong Li, Zhi-Gang Ji
OBJECTIVE: This study aims to investigate the clinical value of laparoscopic enucleation combined with selective arterial embolization for the treatment of renal angiomyolipoma. METHODS: Data of patients who underwent laparoscopic nephron-sparing surgery for renal angiomyolipoma between July 2013 and November 2014 in our center were analyzed. RESULTS: Before surgery, 19 patients underwent selective arterial embolization, while 24 patients did not receive this treatment...
March 31, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/28382565/needle-in-a-haystack-lost-in-transition
#10
Aditya Prakash Sharma, Uttam Kumar Mete, Durgaprasad Bendapuddi, Girdhar Singh Bora, Ravimohan S Mavuduru
A lost needle during minimally invasive surgery is a cause of undue anxiety to the entire surgical team and also causes prolongation of surgical time. There is no literature reporting follow-up of any patient with needle left behind as they are considered as a 'never event' during a surgical procedure. Preventing such events needs vigilance on part of the surgeon and assistant. Here, we report a case of lost needle during performance of a robot-assisted nephron sparing surgery. The robot needed to be de-docked and converted to laparoscopy...
April 5, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28365106/nephron-sparing-surgery-in-the-treatment-of-pediatric-renal-cell-carcinoma-associated-with-xp11-2-translocation-tfe3-gene-fusions
#11
Chao Liu, Weiping Zhang, Hongcheng Song
PURPOSE: To investigate the safety and efficacy of nephron-sparing surgery (NSS) in the treatment of pediatric Xp11.2 translocation renal cell carcinoma (RCC). METHODS: Clinical characteristics of 9 RCC children (7 males and 2 females) with Xp11.2 translocation who received NSS between January 1973 and December 2015 were retrospectively analyzed. The mean age was 7.8years (range: 4.5-13.5years). Xp11.2 translocation RCC was found in the left side in 4 patients and right in 5...
March 27, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28363423/new-technique-for-nephron-sparing-surgery-in-polar-tumours-a-modification-of-the-kim-technique
#12
C Ameri, F M Lopez, G J Vitagliano, H Rios Pita, J M Guglielmi, L Blas
INTRODUCTION AND OBJECTIVES: Nephron-sparing surgery (NSS) is the indication, provided it is feasible and meets the international treatment guidelines. One of the objectives of performing NSS is to reduce the ischemia time as much as possible. We propose a surgical technique for treating polar renal tumours and those larger than 4cm based on the principle of the technique described by Kim in 1964. METHOD: The technique performs a continuous circular suture on the base of the tumour, achieving compression of the renal pole without vascular clamping, facilitating haemostasis and avoiding the blind transfixion performed in Kim's original technique...
March 28, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28328844/clinicopathological-study-on-thyroid-follicular-carcinoma-like-renal-tumor-related-to-serious-hypertension-case-report-and-review-of-the-literature
#13
Hui Wang, Jianpeng Yu, Zhonghua Xu, Gang Li
RATIONALE: Thyroid carcinoma-like tumor of the kidney (TLFCK) is an extremely rare variant of renal cell carcinoma. Most cases were incidentally found, while we report the first case of TLFCK presented with hypertension. PATIENT CONCERNS: A 25-year-old woman was admitted to our hospital presenting with hypertension for ∼20 months, without gross hematuria, weight loss, and flank pain. DIAGNOSES: Imaging studies revealed a right renal mass with multiple calcifications...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28292548/re-elective-nephron-sparing-surgery-decreases-other-cause-mortality-relative-to-radical-nephrectomy-only-in-specific-subgroups-of-patients-with-renal-cell-carcinoma
#14
https://www.readbyqxmd.com/read/28283215/the-use-of-bovine-serum-albumin-glutaraldehyde-tissue-adhesive-bioglue-%C3%A2-for-tumor-bed-closure-following-open-partial-nephrectomy
#15
Z Bahouth, S Halachmi, S Shprits, Y Burbara, O Avitan, I Masarwa, B Moskovitz, O Nativ
OBJECTIVES: To report the results of the use of Bovine Serum Albumin-Glutaraldehyde tissue adhesive (BioGlue®) for tumor bed closure in open nephron-sparing surgery (NSS). MATERIALS AND METHODS: The cohort included 255 patients with enhancing renal mass who underwent open NSS. We used open flank approach, with in-situ hypothermia and enucleation of the tumor. For tumor bed closure, we used the BioGlue(®) sealant for tumor bed filling, without suturing the edges...
March 7, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28279366/-impact-of-robotic-assistance-on-the-use-and-the-outcomes-of-nephron-sparing-surgery-a-single-center-experience
#16
T Fardoun, B Peyronnet, E Oger, G Verhoest, R Mathieu, Z Khene, B Pradere, Q Alimi, A Manunta, N Rioux-Leclercq, J-J Patard, S-F Kammerer-Jacquet, K Bensalah
INTRODUCTION: The aim of this study was to assess the impact of the acquisition of a Da Vinci(®) robot on the use and outcomes of partial nephrectomy (PN). PATIENTS AND METHODS: It was a single center retrospective study including 280 patients who underwent PN from January 2006 to May 2013. The number of PN, tumors and patients' characteristics and perioperative outcomes have been assessed over 3 periods defined according to the main surgical approach: 2006-2008 (open PN), 2008-2010 (laparoscopic PN) and 2010-2013 (robotic PN)...
December 2016: Progrès en Urologie
https://www.readbyqxmd.com/read/28265590/laparoscopic-retroperitoneal-nephron-sparing-surgery-without-renal-artery-clamping-with-preoperative-selective-arterial-embolization-for-management-of-right-renal-angiomyolipoma-of-diameter-10-cm-a-case-report
#17
Tatsuhiko Hoshii, Shinichi Morita, Yohei Ikeda, Go Hasegawa, Tsutomu Nishiyama
A 38-year-old female without the tuberous sclerosis complex was diagnosed with right renal angiomyolipoma of 10 cm in diameter. She underwent laparoscopic retroperitoneal nephron-sparing surgery without renal artery clamping with preoperative selective arterial embolization to avoid a significant risk of hemorrhage and the damage of the renal function during nephron-sparing surgery. The tumor was resected completely. The time taken to complete the procedure was 4 hours 11 minutes and blood loss was 780 mL...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/28211006/surgical-margins-in-nephron-sparing-surgery-for-renal-cell-carcinoma
#18
REVIEW
Dean D Laganosky, Christopher P Filson, Viraj A Master
The oncologic impact of positive surgical margins after nephron-sparing surgery is controversial. Herein, we discuss current data surrounding surgical margins in the operative management of renal cell carcinoma. The prevalence, risk factors, outcomes, and subsequent management of positive surgical margins will be reviewed. Literature suggests that the prevalence of positive surgical margins following kidney surgery varies by practice setting, tumor characteristics, and operation type. For patients undergoing nephron-sparing surgery, it is not necessary to remove a margin of healthy tissue...
January 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28161843/validation-of-3d-volumetric-based-renal-function-prediction-calculator-for-nephron-sparing-surgery
#19
Renato Corradi, Aashish Kabra, Melissa Suarez, Jacob Oppenheimer, Zhamshid Okhunov, Hugh White, Stephanie Nougaret, Hebert A Vargas, Jaime Landman, Jonathan Coleman, Michael A Liss
OBJECTIVE: To evaluate a recently published volume-based renal function prediction calculator intended to be used in small renal mass surgical counseling. METHODS: Retrospective data collection included three-dimensional calculation of renal mass and parenchyma of patients who have undergone extirpative therapy. The predicted glomerular filtration rate (GFR) was calculated using the online calculator. The predicted GFR was compared with the actual 6-month GFR. The Pearson correlation coefficient, paired t test and root-mean-square error (RMSE) are utilized for statistical analysis...
April 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28127175/management-of-bilateral-wilms-tumor-our-experience
#20
Raghunath Bv, Vinay Jadhav, Gowri Shankar, Narendrababu M, Ramesh S
Management of bilateral Wilms' tumor is particularly challenging, considering the chances of recurrence and long-term renal function for affected patients. Aggressive surgical resection to prevent recurrence must be balanced with the desire to preserve renal function. We evaluated our experience in the management of bilateral Wilms' tumor stressing the challenges encountered in decision making and the role of nephron sparing surgery. We had four children presenting with bilateral Wilms' tumor. All of them were appropriately staged and given standard chemotherapy as per NWTS-5 guidelines...
March 2017: Indian Journal of Surgical Oncology
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