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Alicia Maldré Vaca, Carolina Beatriz Guido, Liliana Del Valle Sosa, Juan Pablo Nicola, Jorge Mukdsi, Juan Pablo Petiti, Alicia Ines Torres
Extensive evidence has revealed variations in the number of hormone-producing cells in the pituitary gland, which occur under physiological conditions such as gestation and lactancy. It has been proposed that new hormone-producing cells differentiate from stem cells. However, exactly how and when this takes place is not clear. In this work, we used immunoelectron microscopy to identify adult pituitary stem/progenitor cells (SC/P) localized in the marginal zone (MZ), and additionally, we detected GFRa2-, Sox2-, and Sox9-positive cells in the adenoparenchyma (AP) by fluorescence microscopy...
August 1, 2016: American Journal of Physiology. Endocrinology and Metabolism
María Vásquez, Boris Lira, José Rodríguez, Néstor Falcón, Jorge Ocampo, Fabián Nishida, Claudio Barbeito, Carolina Zanuzzi
Paneth cells are secretory epithelial cells of the innate immune system of the intestine of several mammals, including alpacas. Little is known about the latter; thus, in the present study we described the morphology and histochemical characteristics of Paneth cells in healthy fetuses, and young and adult alpacas. For this purpose, samples of duodenum, jejunum and ileum were taken from 6 fetuses at different days of pregnancy (between days 221-330), 66 offsprings (between 0 and 45-days-old) and 5 adult alpacas (>2-years-old)...
August 2016: Tissue & Cell
M Isabel Cordero, François Ansermet, Carmen Sandi
Human literature has linked adverse early life experiences with an increased risk to develop violent behaviors in both boys and girls. We have previously shown that male rats submitted to stress during the peripuberty period display as adults abnormal aggressive behavior against both male intruders and female partners. In the present study, we examined whether the same stress protocol would affect the development of aggressive behaviors in female rats. We evaluated the behavior of these peripuberty stressed female rats when confronted, at adulthood, with either female or male intruders, and during their cohabitation with male partners...
November 2013: Psychoneuroendocrinology
Mirna Rocío Yabur-Espitia, Emilia Patiño-Bahena, Berenice Cruz-Prieto, Gonzalo Espinosa-Islas, Nilda Espínola-Zavaleta
INTRODUCTION: The double-chambered right ventricle (DCRV) is an uncommon congenital heart disease; it represents the 0,5% of these congenital cardiopathies. OBJECTIVE: To describe the clinical and echocardiographic characteristics of a series of 11 patients. METHODS: Eleven patients with DCRV were studied. A complete medical history, chest radiograph, electrocardiogram, and transthoracic echocardiography were performed. RESULTS: The median age of studied patients was 10 years...
January 2013: Archivos de Cardiología de México
Laura Paternain, Eva Martisova, Fermín I Milagro, María J Ramírez, J Alfredo Martínez, Javier Campión
An early-life adverse environment has been implicated in the susceptibility to different diseases in adulthood, such as mental disorders, diabetes and obesity. We analyzed the effects of a high-fat sucrose (HFS) diet for 35 days in adult female rats that had experienced 180 minutes daily of maternal separation (MS) during lactancy. Changes in the obesity phenotype, biochemical profile, levels of glucocorticoid metabolism biomarkers, and the expression of different obesity- and glucocorticoid-metabolism-related genes were analyzed in periovaric adipose tissue...
September 2012: Disease Models & Mechanisms
Paula N Gonzalez, Benedikt Hallgrímsson, Evelia E Oyhenart
Environmental perturbations of many kinds influence growth and development. Little is known, however, about the influence of environmental factors on the patterns of phenotypic integration observed in complex morphological traits. We analyze the changes in phenotypic variance-covariance structure of the rat skull throughout the early postnatal ontogeny (from birth to weaning) and evaluate the effect of intrauterine growth retardation (IUGR) on this structure. Using 2D coordinates taken from lateral radiographs obtained every 4 days, from birth to 21 days old, we show that the pattern of covariance is temporally dynamic from birth to 21 days...
February 2011: Journal of Anatomy
V Lorenzo, A Alvarez, A Torres, V Torregrosa, D Hernández, E Salido
Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder characterized by allelic and clinical heterogeneity. We aim to describe the presentation and full single-center experience of the management of PH1 patients bearing the mutation described in our community (I244T mutation+polymorphism P11L). Since 1983, 12 patients with recurrent renal lithiasis have been diagnosed with PH1 and renal failure in the Canary Islands, Spain. Diagnostic confirmation was based on the presence of oxalosis in undecalcified bone or kidney allograft biopsy, reduced alanine:glyoxylate aminotransferase activity in liver biopsy, and blood DNA analysis...
September 2006: Kidney International
A R Bort, E Sevilla-Romero, M J Gamborino, A Muñoz, M D Pinazo-Durán
PURPOSE: It is well known that vertebrates Central Nervous System reacts to a wide variety of hormones, and growth factors. However the basic maturation mechanisms and remodelling processes remain in general unknown. Thyroid hormones tri-iodothyronine (T(3)) and thyroxine (T(4)) modulate this metabolism, playing a role in cell differentiation and proliferation and in gene expression during growth. The aim of the present study was to investigate whether or not low levels of thyroid hormone in blood, obtained with an experimental model of congenital neonatal hypothyroidism referred to herein, may induce changes in optic nerve development, mainly in processes of macroglial cell genesis and myelination...
February 2002: Archivos de la Sociedad Española de Oftalmología
G Garcia, P Tagliaferro, A Bortolozzi, M J Madariaga, A Brusco, A M Evangelista de Duffard, R Duffard, J P Saavedra
2,4-D is a chlorophenoxyherbicide used worldwide. We have studied the morphological alterations of 5-HT neurons and glial cells in the mesencephalic nuclei of adult rats exposed to 2,4-D both perinatally (during pregnancy and lactation) and chronically (during pregnancy, lactation and after weaning) with quantitative methods. Pregnant rats were daily exposed to 70 mg/kg of 2,4-D from gestation day (GD) 16 to post-natal day (PND) 23 through diet. After weaning, pups were assigned to one of two sub-groups: T1 (fed with untreated diet until PND 90) and T2 (maintained with 2,4-D diet until PND 90)...
December 2001: Neurotoxicology
E H Aguirre-González, L Verduzco-Rodríguez, J A Palet-Guzmán
Sixteen cases of granulomatous mastitis were seen in the Breast Clinic of the Rio Blanco Regional Hospital in Veracruz, México. The mean age was 41.7 years (range 22-62), mean previous pregnancies was 5. Lactancy in last 6 months was registered in 50% of the cases, but no cases of puerperal mastitis were seen. Seventy five percent of the patients presented with a breast mass (mean 6 cm), suspicious of cancer in 62.5%. In 2 of 16 cases (12.5) there was an associated breast carcinoma, and in one case tuberculosis was the etiology...
November 1999: Ginecología y Obstetricia de México
M D Rodríguez, M Sánchez, H García
The hypocholesterolaemic drug policosanol was administered to Sprague-Dawley rats of both sexes throughout three successive generations at concentrations of 0, 5, 50 and 500 mg/kg bw/day by gavage. For each generation two litters were reared until they were at least 3 weeks old. No clinical signs which could be related to the administration of the test substance were observed in the F0, F1b and F2b parents. There were no differences among groups in the number of animals that conceived, the number of pups born live or dead, the rate of male to female pups, the number of pups that survived until weaning and the pups' body weights through the lactancy...
February 7, 1997: Toxicology Letters
F J Posadas-Robledo, E Martínez-Hernández, L Hernández-Castillo, Y García-Hernández, T J Guerrero
In a prospective longitudinal study carried out in the Ginecoobstetric Department of the HGZ 6 Cd. Valles S.L.P., from March 1st to July 15th 1995. One hundred patient were evaluated 24 h after puerperium (in hospital), and 20 and 40 days later at home. With the objective to determine the continuity of lactancy, because all mothers were informed and trained about the benefits of human milk. 31% of the pregnancies were cesarean section and 69% vaginal. A lost of continuity was found in 43% at 20 days and 44% at 40 days...
September 1996: Ginecología y Obstetricia de México
J L Hernández Horta, Q Alonso Uriarte, V Cortés Gallegos
In order to establish a relationship between hyperprolactinemia and FSH-LH associated to the ovarian physiology postpartum, a clinical/endocrinological follow-up was performed during a period of twelve months in a cohorte of seventeen women beginning pregnancy resolution. The study had two phases: Lactancy (LAC) and Post-lactancy (LAC) and Post-lactancy (POST-LAC). In both phases blood samples were obtained every week from the first one through the 52nd, to quantitate FSH, LH, prolactin (PRL) and estradiol (E-2)...
June 1994: Ginecología y Obstetricia de México
E Molina, F Hidalgo, S Fernández, A Casanova, L Martín Sanz
Three cases of segmental dilatation of ileum surgically are presented. Authors have reviewed medical literature since the first case reported in 1959, and have been able to collect 33 cases. Although it is considered an identical entity involving either colon or small bowel, clinical picture and age of presentation are different. Cases involving the colon have a clinical picture very similar to that of Hirschsprung's disease, usually appearing in the lactancy or later on. Cases involving ileum or jejunum usually are manifested as a neonatal bowel obstruction...
December 1984: Anales Españoles de Pediatría
I Plaza, R P Mariscal, J Ros-Jellici, M T Muñoz, J Otero, R Madero, J Baeza, C Ruiz-Jarabo, M J Ceñal, M I Parra
Fuenlabrada is at the present time the most industrialized town placed at the south are of Madrid. This population has some peculiar attractive characteristics from the epidemiologic point of view. Perhaps the most important is that the majority of its inhabitants are immigrant from other depressed rural areas of the country, with a low socio-economic and cultural level. The new conditions of life could have changed the life expectation and the causes of morbidity and mortality of this population. Between 1981 and 1984 we have studied the prevalence of cardiovascular risk factors in children and adolescents of its population, the relationships with cardiovascular risk factors and cardiovascular disease of the family and type of lactancy of the newborn...
May 1989: Revista Española de Cardiología
M J Cabañas Bravo, C Izaguirre Zugazaga, A Fuertes Domínguez, N Baquedano Escolano, M C Crespo Mainar, A López Solsona
We are having an internal, retrospective audic of 302 medical care histories corresponding to all infants between 0 and 18 months registered at the health centre between 1st Nov. 1986 and 30th April 1988, with purpose of determining the degree of quality achieved by the professional staff in the completion of the medical records, systematic examinations of health and objectives proposed in the Centre's Program for Infants, similarly assessing the adeherance of patients to the same. We found a level of those registered globally, of 81 por 100 of all analysed data, which we assessed as improvable...
August 1990: Anales Españoles de Pediatría
A Paredes López
This report has the purpose to analyze the risk factors for Breast Cancer in the population of female Mexican workers and their relatives living in the same socio-cultural environment. These risk factors were: age, number of pregnancies, age while first pregnant, early menarca, late menopause, no lactance, use of contraceptive pills, hereditary, mammary pathology, obesity, diabetes mellitus. The questions were asked to women older than 30 years of age to which a breast biopsy had been practiced; in 123 patients the biopsy reported a breast carcinoma in 291 patients the hystological reports showed a benign pathology other than cancer...
February 1991: Ginecología y Obstetricia de México
F Buitrago Ramírez, L J Molina Martínez, A Blanco Ovejero, J Guillén Regodón, M J Dávila Tena, J A Galán González
Authors present qualitative and quantitative results of a health quality assurance study of pediatric population in primary care. Ten criteria were accepted by consensus and level of 90% of fulfilling was taken as optimal standard. None of the criteria reached that level. The best fulfilled ones were those referring to pregnancy (89%), vaccination (87.7%), lactancy (87%), weight at birth (86.7%), parturition (84%) and newborn period (82%). Among qualitative results most remarkable were vaccination coverage (95...
September 1991: Anales Españoles de Pediatría
A M de Duffard, M N de Alderete, R Duffard
Brain concentrations of Serotonin (5-HT) and 5-hydroxyindolacetic acid (5-HIAA) were determined in male, mother and virgin female adult rats after exposure to 69 mg/kg body weight/day of 2,4-dichlorophenoxyacetic butyl ester (2,4-Dbe) during 15 or 45 consecutive days. Both 5-HT and 5-HIAA concentrations were increased in the brain. These effects reverted to levels even lower than controls, when the animals were fed an untreated diet after the 2,4-Dbe treatment. High 5-HT and 5-HIAA brain concentrations were also observed in adult rats born from treated mothers (during pregnancy and lactancy) and fed with or without treated diet after weaning...
December 3, 1990: Toxicology
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