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https://www.readbyqxmd.com/read/29684638/medication-related-osteonecrosis-of-the-jaw-a-survey-of-knowledge-attitudes-and-practices-among-dentists-in-the-principality-of-asturias-spain
#1
M Escobedo, L García-Consuegra, S Junquera, S Olay, G Ascani, L Junquera
INTRODUCTION: The objective of this study was to investigate the knowledge and capabilities of dentists and dental students in their last year of study in regard to risk factors of medication-related osteonecrosis of the jaw (MRONJ) in Spain. MATERIAL AND METHOD: We conducted a cross-sectional study consisting of a questionnaire survey in Asturias, Spain. The study was divided into three groups: dentists who worked for the public dental health care system (n=32), dentists who worked exclusively as private health care practitioners (n= 136), and dental students in their last year (year five) of study (n= 38)...
April 20, 2018: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29684310/assessing-the-quality-of-life-in-patients-with-dentofacial-deformities-before-and-after-orthognathic-surgery
#2
Hong Sun, Hong-Tao Shang, Li-Sheng He, Ming-Chao Ding, Zhong-Ping Su, Yu-Lin Shi
PURPOSE: This study aimed to assess the effect of health-related quality of life (QoL) among patients with dentofacial deformities who underwent orthognathic surgery compared with a control group without dentofacial deformities by use of generic oral health and condition-specific approaches. PATIENTS AND METHODS: In this prospective study, 2 questionnaires were administered to 85 patients (31 male and 54 female patients) who were evaluated before undergoing orthognathic surgery...
March 31, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29682552/prefabricated-bar-system-for-immediate-loading-in-edentulous-patients-a-5-year-follow-up-prospective-longitudinal-study
#3
Enrico F Gherlone, Gianpaolo Sannino, Andrea Rapanelli, Roberto Crespi, Giorgio Gastaldi, Paolo Capparé
Objectives: The aim of this clinical study was to evaluate a new type of prefabricated bar system, supported by axial and tilted implants at 5-year follow-up. Materials and Methods: Twenty-nine consecutive participants (19 females, 10 males) (mean age 61.4 years), edentulous in one or both jaws, with severe atrophy of the posterior regions, were treated according to the All-on-four® protocol with immediately loaded axial (64) and tilted (64) implants supporting complete-arch screw-retained prostheses (12 maxillary, 20 mandibular) featuring a prefabricated bar as framework...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29680992/comparison-of-mucosal-and-mucoperiosteal-wound-cover-for-the-treatment-of-medication-related-osteonecrosis-of-the-jaw-lesions-a-retrospective-cohort-study
#4
Nicola Nonnenmühlen, A Burnic, A Bartella, B Lethaus, F Gerhards, O Ristow, C Pautke, F Hölzle, T Steiner
OBJECTIVES: Actually, there is no detailed guidance on how to deal with wound closure after surgical removal of medication-related osteonecrosis of the jaw (MRONJ) lesions. This study attempts to compare the difference in outcome between the mucosal and the mucoperiosteal flap closure after surgery. PATIENTS AND METHODS: In this retrospective monocentric cohort study, patients (n = 61; 35 female/26 male) suffering from MRONJ and requiring surgical therapy at the University of Aachen between 2013 and 2015 were included...
April 22, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29680853/osteonecrosis-of-the-jaw-in-patients-traited-by-denosumab-for-malignant-bone-disease-descriptive-study-on-9-cases
#5
R Lan, M Hadj-Saïd, J-M Foletti, E Massereau, C Chossegros
BACKGROUND: This study examines the epidemiological and clinical characteristics and therapeutic outcomes in patients with denosumab related-osteonecrosis of the jaw (DRONJ). MATERIAL AND METHODS: The patients included are all being monitored by three oral and maxillofacial surgery departments for an osteonecrosis of the jaw (ONJ) linked to denosumab alone for the treatment of malignant bone disease between 2010 and 2016. Clinical and epidemiological data of these patients was indexed and characteristics of the DRONJ were analyzed...
April 22, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29677217/optimisation-of-three-dimensional-lower-jaw-resection-margin-planning-using-a-novel-black-bone-magnetic-resonance-imaging-protocol
#6
Astrid M Hoving, Joep Kraeima, Rutger H Schepers, Hildebrand Dijkstra, Jan Hendrik Potze, Bart Dorgelo, Max J H Witjes
BACKGROUND: MRI is the optimal method for sensitive detection of tumour tissue and pre-operative staging in oral cancer. When jawbone resections are necessary, the current standard of care for oral tumour surgery in our hospital is 3D virtual planning from CT data. 3D printed jawbone cutting guides are designed from the CT data. The tumour margins are difficult to visualise on CT, whereas they are clearly visible on MRI scans. The aim of this study was to change the conventional CT-based workflow by developing a method for 3D MRI-based lower jaw models...
2018: PloS One
https://www.readbyqxmd.com/read/29676286/automated-human-skull-landmarking-with-2d-gabor-wavelets
#7
Markus A de Jong, Atilla Gül, Jan Pieter de Gijt, Maarten J Koudstaal, Manfred Kayser, Eppo B Wolvius, Stefan Böhringer
Landmarking of CT scans is an important step in the alignment of skulls that is key in surgery planning, pre-/post-surgery comparisons, and morphometric studies. We present a novel method for automatically locating anatomical landmarks on the surface of cone beam CT-based image models of human skulls using 2D Gabor wavelets and ensemble learning. The algorithm is validated via human inter- and intra-rater comparisons on a set of 39 scans and a skull superimposition experiment with an established surgery planning software (Maxilim)...
April 20, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29668626/effect-of-arthrocentesis-plus-platelet-rich-plasma-and-platelet-rich-plasma-alone-in-the-treatment-of-temporomandibular-joint-osteoarthritis-a-retrospective-matched-cohort-study-a-strobe-compliant-article
#8
Shang-Lun Lin, Chiang-Chin Tsai, Shang-Liang Wu, Shun-Yao Ko, Wei-Fan Chiang, Jung Wu Yang
Although the research on using platelet-rich plasma (PRP) for temporomandibular joint osteoarthritis (TMJ-OA) has advanced, no unified standards exist for determining the joint use of arthrocentesis and the injection dose and frequency of PRP. This study aimed to compare the efficacy of 2 TMJ-OA treatment approaches, arthrocentesis plus platelet-rich plasma (A+PRP) and PRP alone, and attempted to provide another potential treatment option with a single injection of 2 mL of high-concentration and high-purity PRP...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29667467/mandibular-asymmetries-and-associated-factors-in-orthodontic-and-orthognathic-surgery-patients
#9
Guilherme Thiesen, Bruno F Gribel, Maria Perpétua M Freitas, Donald R Oliver, Ki Beom Kim
OBJECTIVES: To estimate the prevalence of mandibular asymmetries in orthodontic and orthognathic surgery patients and to investigate demographic and skeletal factors associated with this disharmony. MATERIALS AND METHODS: Cone-beam computed tomography images of 1178 individuals aged 19 through 60 years with complete dentitions were analyzed. Outcomes were classified as relative mandibular symmetry, moderate asymmetry, and severe asymmetry. Factors recorded included sex, age, side of mandibular deviation, sagittal jaw relationship, vertical skeletal pattern, angle of the cranial base, and maxillary asymmetry...
April 18, 2018: Angle Orthodontist
https://www.readbyqxmd.com/read/29665346/chronological-age-as-factor-influencing-the-dental-implant-osseointegration-in-the-jaw-bone
#10
Jakub Papež, Taťjana Dostálová, Karel Chleborád, Pavel Kříž, Jakub Strnad
The objectives of this study were to evaluate osseointegration of dental implant in the jaw bone in the young and elderly population and comparing the results to assess indicators and risk factors as age for the success or failure of dental implants. A retrospective study of 107 implants (Impladent, LASAK, Czech Republic) was prepared. The patients at implants surgery were divided in three groups. The patients were followed-up for a 7-year period. We evaluated osseointegration from long term point of view as a change of marginal bone levels close to dental implant...
2018: Prague Medical Report
https://www.readbyqxmd.com/read/29660305/temporomandibular-joint-reconstruction-in-patients-with-autoimmune-connective-tissue-disease
#11
Pushkar Mehra, Charles Henry, Mohammed Nadershah
PURPOSE: To evaluate clinical outcomes in patients with autoimmune or connective tissue (CT) disease undergoing temporomandibular joint (TMJ) reconstruction. MATERIALS AND METHODS: Patients were divided into 2 groups based on type of TMJ reconstruction. Patients in group 1 (n = 9) underwent autogenous reconstruction and had a diagnosis of rheumatoid arthritis (5), lupus arthritis (1), and psoriatic arthritis (3). Patients in group 2 (n = 2l) had alloplastic reconstruction with a patient-fitted total joint prosthesis (TMJ Concepts, Ventura, CA) and had a diagnosis of rheumatoid arthritis (15), lupus (3), and psoriatic arthritis (3)...
March 22, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29652755/comprehensive-treatment-and-rehabilitation-of-patients-with-osteosarcoma-of-the-mandible
#12
Anatolij Sergeevich Utyuzh, Alexei Valerievich Yumashev, Hans Walter Lang, Angelina Olegovna Zekiy, Richard Michailovich Lushkov
OBJECTIVE: The article studies state-of-the art physical therapeutic techniques as a high degree of relevance to minimize invalidation and improve quality of life for patients with dental osteosarcoma. MATERIALS AND METHODS: A randomized controlled clinical trial was conducted in 21 patients with osteogenic sarcoma of mandible (C41.1). There were 10 patients in the experimental group and 11 patients in the control group. RESULTS: A comprehensive treatment and rehabilitation program for patients with osteosarcoma of mandible was developed...
April 12, 2018: Implant Dentistry
https://www.readbyqxmd.com/read/29651856/postoperative-fixation-after-repositioning-of-premaxilla-in-a-patient-with-bilateral-cleft-lip-and-palate-case-report
#13
M Koťová, M Dušková, E Leamerová, W Urbanová, K Schwarzmannová, K Novotná, A Sukop
This article presents orthodontic-surgical treatment in an eight-year-old patient with bilateral cleft lip and palate where premaxilla was surgically repositioned in the mixed dentition stage. By cranial and dorsal insertion of the premaxilla were created satisfactory occlusal relationship for ongoing eruption of permanent teeth, together with functional lip closure, improved pronunciation and a positive change in appearance of the centrofacial area. Reposition of premaxilla was associated with bilateral alveolar bone grafting of the cleft defect with cancellous bone from the iliac crest...
2018: Acta Chirurgiae Plasticae
https://www.readbyqxmd.com/read/29650420/denosumab-treatment-of-inoperable-or-locally-advanced-giant-cell-tumor-of-bone-multicenter-analysis-outside-clinical-trial
#14
Piotr Rutkowski, Louie Gaston, Aneta Borkowska, Silvia Stacchiotti, Hans Gelderblom, Giacomo Giulio Baldi, Emanuela Palmerini, Paolo Casali, Alessandro Gronchi, Michael Parry, Domenico Andrea Campanacci, Guido Scoccianti, Michal Wagrodzki, Stefano Ferrari, Sander Dijkstra, Andrzej Pieńkowski, Robert Grimer
BACKGROUND: Giant cell tumor of bone (GCTB) is an osteolytic, locally aggressive, rarely metastazing bone tumor. This is a retrospective study evaluating a large series of GCTB patients treated with denosumab in routine practice in 6 European reference centers. METHODS: Patients with locally advanced, unresectable or metastatic GCTB, treated with denosumab outside clinical trials were eligible. Primary end-point was progression-free survival (PFS) for all patients; secondary end-points were: type of surgery, relapse rate and event-free survival for patients after preoperative denosumab + surgery...
March 31, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29625030/is-counterclockwise-rotation-with-double-jaw-orthognathic-surgery-stable-in-the-long-term-in-hyperdivergent-class-iii-patients
#15
Yasemin Bahar Acar, Necip Fazıl Erdem, Ahmet Hüseyin Acar, Ahmet Nejat Erverdi, Kemal Ugurlu
PURPOSE: To evaluate the long-term postsurgical stability of counterclockwise rotation of the occlusal plane (OP) in double-jaw orthognathic surgery in patients with hyperdivergent Class III malocclusion. MATERIALS AND METHODS: This retrospective cohort study evaluated the postsurgical stability of orthognathic surgery in patients with skeletal Class III malocclusion and counterclockwise rotation of the maxillomandibular complex with an OP change of at least -2°...
March 15, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29623583/pathology-findings-and-clinical-outcomes-after-risk-reduction-salpingo-oophorectomy-in-brca-mutation-carriers-a-multicenter-spanish-study
#16
L Minig, S Cabrera, R Oliver, A Couso, M J Rubio, S Iacoponi, M B Martin-Salamanca, S Carballo-Rastrilla, J M Cádenas-Rebollo, A García-Garcia, B Gil-Ibáñez, M J Juan-Fita, M G Patrono
OBJECTIVE: To determine the incidence of serous tubal intraepithelial carcinoma (STIC) after risk reduction salpingo-oophorectomy(RRSO), and to describe oncological outcomes after RRSO. MATERIALS AND METHODS: BRCA pathogenic mutation carriers who had undergone an RRSO were evaluated in this retrospective multicenter observational study. Patients were only included when fallopian tubes were analyzed following the protocol for Sectioning and Extensively Examining the FIMbria (SEE-FIM)...
April 5, 2018: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29615315/the-use-of-buccal-fat-pad-in-surgical-treatment-of-krokodil-drug-related-osteonecrosis-of-maxilla
#17
Koryun Hakobyan, Yuri Poghosyan, Aram Kasyan
'Krokodil' is the street name of a new synthetic drug mixture. It is a light brown liquid that is used intravenously without previous purification. Osteonecrosis of the jaw (ONJ) is a common complication among Krokodil users. Krokodil drug-related ONJ presents as alveolar process exposure in the oral cavity. Surgery is the main method for treatment of Krokodil drug-related ONJ patients. In a study by Poghosyan et al., no cases of recurrence were seen after surgery on the maxilla, but 38% of cases (8/21) developed an oroantral communication after surgical treatment for maxillary osteonecrosis (Poghosyan et al...
March 20, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29602860/protocol-for-the-trismus-trial-therabite-versus-wooden-spatula-in-the-amelioration-of-trismus-in-patients-with-head-and-neck-cancer-randomised-pilot-study
#18
Rana Lee, Alex Molassiotis, Simon N Rogers, Rhiannon Tudor Edwards, David Ryder, Nick Slevin
INTRODUCTION: Patients can develop trismus from their head and neck cancer or as a result of treatment. Trismus affects the jaw muscles and makes mouth opening difficult. To potentially combat trismus, patients could undertake proactive jaw stretching exercises prior to, during and after radiotherapy, although currently these are not the standard of care. METHODS AND ANALYSIS: This is a randomised, open-label, controlled, two-centre feasibility study, to assess the objective and subjective effectiveness and cost-effectiveness of therabite use compared with wooden spatula in ameliorating trismus in patients treated for stage 3 and 4 oral and oropharyngeal cancer, managed either by primary surgery followed by (chemo)radiotherapy or primary (chemo)radiotherapy...
March 30, 2018: BMJ Open
https://www.readbyqxmd.com/read/29594246/surgery-vs-primary-radiotherapy-in-early-stage-oropharyngeal-cancer
#19
Catia Pedro, Beatriz Mira, Pedro Silva, Eduardo Netto, Rute Pocinho, António Mota, Miguel Labareda, Miguel Magalhães, Susana Esteves, Filomena Santos
Background: Early-stage oropharyngeal squamous cell carcinoma (OPSCC) can currently be treated by surgical resection or definitive radiotherapy (RT). The aim of this study is to review the outcomes of early-stage OPSCC submitted to surgery or primary RT. Preliminary results have shown similar overall survival (OS) and locoregional recurrence-free survival (LRFS). Material/Methods: Retrospective study of patients with cT1-T2 cN0-N1 OPSCC, diagnosed between January 2009 and December 2014, treated with surgery or primary RT...
February 2018: Clinical and Translational Radiation Oncology
https://www.readbyqxmd.com/read/29574815/reconstruction-of-major-defects-of-the-jaws
#20
M D Batstone
Prosthetic replacements in the 19th and early 20th century were superseded by pedicled flaps and obturators. These have subsequently been superseded by free tissue transfer which currently is the mainstay of reconstructive jaw surgery. Although malignant and benign processes of the jaws are the predominant cause of segmental defects, a significant proportion still occurs due to trauma, or even iatrogenic causes such as radiotherapy. The varied aetiologies demand a nuanced approach to reconstruction and although the techniques remain similar the timing can be quite different...
March 2018: Australian Dental Journal
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