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https://www.readbyqxmd.com/read/29223639/extensive-phenotyping-of-the-orofacial-and-dental-complex-in-crouzon-syndrome
#1
Alexander Khominsky, Robin Yong, Sarbin Ranjitkar, Grant Townsend, Peter J Anderson
OBJECTIVES: Fibroblast growth factor receptor 2 (FGFR2) C342Y/+ mutation is a known cause of Crouzon syndrome that is characterised by craniosynostosis and midfacial hypoplasia. Our aim was to conduct extensive phenotyping of the maxillary, mandibular and dental morphology associated with this mutation. MATERIALS AND METHODS: Morphometric data were obtained from 40 mice, representing two genotypes (Crouzon and wild-type) and two sexes (males and females) (n=10 in each group)...
October 27, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29223315/metal-free-full-arch-fixed-prosthesis-for-edentulous-mandible-rehabilitation-on-four-implants
#2
Alfredo Passaretti, Giulia Petroni, Giovanna Miracolo, Valeria Savoia, Angelo Perpetuini, Andrea Cicconetti
PURPOSE: The goal of this work is to describe an implant-prosthetic protocol for rehabilitation of edentulous mandible, by using a fixed prosthesis made of fiber-reinforced composite material (FRC). The protocol contemplates a minimal invasive surgery and ensures predictable and safe results, with good aesthetic and performance combined to cost savings. METHODS: FRC material is used to build the substructure of a prosthetic framework supported by four short implants (5mm long and 4mm wide)...
December 6, 2017: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/29222966/optimizing-functional-outcomes-in-mandibular-condyle-reconstruction-with-the-free-fibula-flap-using-computer-aided-design-and-manufacturing-technology
#3
Z-Hye Lee, Tomer Avraham, Casian Monaco, Ashish A Patel, David L Hirsch, Jamie P Levine
PURPOSE: Mandibular defects involving the condyle represent a complex reconstructive challenge for restoring proper function of the temporomandibular joint (TMJ) because it requires precise bone graft alignment for full restoration of joint function. The use of computer-aided design and manufacturing (CAD/CAM) technology can aid in accurate reconstruction of mandibular condyle defects with a vascularized free fibula flap without the need for additional adjuncts. The purpose of this study was to analyze clinical and functional outcomes after reconstruction of mandibular condyle defects using only a free fibula graft with the help of virtual surgery techniques...
November 15, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29215447/cross-sectional-study-of-four-serological-bone-turnover-markers-for-the-risk-assessment-of-medication-related-osteonecrosis-of-the-jaw
#4
Andre Peisker, Gregor F Raschke, Mina D Fahmy, Arndt Guentsch, Korosh Roshanghias, Kai C König, Stefan Schultze-Mosgau
BACKGROUND: Despite the benefits related to the use of bisphosphonates and denosumab, medication-related osteonecrosis of the jaw (MRONJ) is a serious complication. The purpose of this study was to investigate the utility of 4 biochemical markers including serum c-terminal telopeptide cross-link of type I collagen (s-CTX), serum osteocalcin (s-OC), serum parathormon (s-PTH), and serum bone-specific alkaline phosphatase (s-BAP) as useful clinical tools to help assess the risk for MRONJ prior to invasive oral surgery...
December 6, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29215195/temporomandibular-joint-positional-change-accompanies-post-surgical-mandibular-relapse-a-long-term-retrospective-study-among-patients-who-underwent-mandibular-advancement
#5
M Z Miao, B Wang, D Wu, S Zhang, S Wong, O Shi, A Hu, L Mao, B Fang
OBJECTIVE: This study evaluated the relationship between follow-up temporomandibular joint positional change and mandibular stability among patients who had orthognathic and orthodontic treatment for a skeletal Class II malocclusion. METHODS: Thirty-seven patients who underwent 2-jaw surgery (Le Fort I osteotomy, bilateral sagittal split ramus osteotomy and genioplasty with rigid internal fixation) were included with an average follow-up length of 8.10 ± 2.06 years...
December 7, 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/29209690/prosthetic-rehabilitation-involving-the-use-of-implants-following-a-fibula-free-flap-reconstruction-in-the-treatment-of-osteosarcoma-of-the-maxilla-a-case-report
#6
E Brauner, A Quarato, F De Angelis, G Pompa, S Jamshir, V Valentini, S Di Carlo
INTRODUCTION: Osteosarcoma is an aggressive primary bone tumor composed of connective tissue cells directly producing osteoid and bone. Prosthetic rehabilitations in post-oncological patients after bone reconstruction are not substantially different than those of patients affected by severe atrophy of upper or lower jaw after bone reconstruction. The treatment for patients with a malignant neoplasia of the oral cavity requires multidisciplinary approach by a team of different specialists that follow the patient through the phases of diagnosis, therapy and oral rehabilitation...
November 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29208785/use-of-a-partial-thickness-flap-for-guided-bone-regeneration-in-the-upper-jaw
#7
Gianluca Porcaro, Alberto Busa, Edoardo Bianco, Gianluigi Caccianiga, Marcello Maddalone
INTRODUCTION: Guided bone regeneration (GBR) aims to restore adequate bone volume for the placement of implants in an ideal location. In this article, we analyze different surgical techniques for tissue management during GBR and a modified partial-thickness surgical approach. MATERIALS AND METHODS: In a year's time span, five patients were enrolled in the study: Four women and one man (aged 44-59 years). In four patients, a GBR with simultaneous implant placement was adopted, whereas in another patient, a delayed implant placement was done...
December 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29208050/robotic-assisted-total-mesorectal-excision-with-the-single-docking-technique-for-patients-with-rectal-cancer
#8
Ching-Wen Huang, Hsiang-Lin Tsai, Yung-Sung Yeh, Wei-Chih Su, Ming-Yii Huang, Chun-Ming Huang, Yu-Tang Chang, Jaw-Yuan Wang
BACKGROUND: The robotic system has advantages of high-definition three-dimensional vision and articular instruments with high dexterity, allowing more precise dissection in the deep and narrow pelvic cavity. METHODS: We enrolled 95 patients with stage I-III rectal cancer (adenocarcinoma) who underwent totally robotic-assisted total mesorectal excision (TME) with single-docking technique at a single institution between September 2013 and December 2016. RESULTS: Of the 95 patients, 48 (50...
December 5, 2017: BMC Surgery
https://www.readbyqxmd.com/read/29207788/hyperparathyroidism-during-pregnancy-a-diagnostic-and-therapeutic-challenge
#9
Richa Sharma, Bhanupriya, Vishnu Bhartiya, Kiran Guleria, Amita Suneja
Primary Hyperparathyroidism (PHP) is a rare event in pregnancy; Maternal complications in PHP patients can be as high as 67%. It can be overlooked easily because of many similar complaints shared by hyperparathyroidism and pregnancy such as nausea and vomiting, gastritis, bone aches, easy fatigability. Hypercalcemic crisis can develop resulting in coma and death. Neonatal effects are tetany and death in about 80% of cases. We report a case, of an antenatal woman at 30 weeks gestation with complains of painful swelling in left lower jaw and below right knee, pain over right hip joint and frequent episodes of gastritis...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29199347/-analysis-of-factors-affecting-soft-tissue-infection-after-oral-and-maxillofacial-debridement
#10
Liu-Hong Wang, Zheng Yang, Hui Yang, Xin-Tian Lou, Yi-Lin Wang, Xiang-Qun Qi
PURPOSE: To explore the factors affecting soft tissue infection after oral and maxillofacial debridement. METHODS: Fifty hundred patients with debridement were enrolled in this study from January 2013 to June 2016. The patients were divided into 2 groups according to soft tissue infection, 18 cases in infection group and 482 cases in non-infection group. Age, mean time to surgery, average length of stay, duration of antibiotics use, abbreviated injury scale (AIS), combined injuries, maxillofacial fractures, soft tissue injury, type of fracture, and history of diabetes were recorded and analyzed using SPSS 19...
August 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/29196905/oncology-curricula-in-postgraduate-general-dentistry-programs-a-survey-of-residency-program-directors
#11
Evan B Rosen, Alexander Drew, Joseph M Huryn
Management of patients undergoing treatment for cancer requires a multidisciplinary team including general dentistry providers; however, the relative knowledge and training of general dentists in the management of this patient population are relatively unknown. The purpose of this study was to assess the oncology curricula of postgraduate general dentistry training programs, from the perspective of the program directors, to better understand the opportunities for and/or barriers to dental care for cancer patients...
December 1, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29196831/laser-for-bone-healing-after-oral-surgery-systematic-review
#12
REVIEW
Claudio Noba, Anna Carolina Volpi Mello-Moura, Thais Gimenez, Tamara Kerber Tedesco, Cacio Moura-Netto
The purpose of this study is to perform a systematic review on the use of lasers in oral surgery for bone healing. Selection of articles was carried out by two evaluators in Pubmed and Web of Science databases for published articles and OpenGray for gray literature. Search strategy was developed based on the PICO Question "Does the use of lasers after oral surgery improve bone healing?". Eligibility criteria were: being on laser; evaluate bone healing; involve oral surgery; do not be about implant, periodontics, orthodontics, osteonecrosis or radiotherapy, nor revisions, clinical cases, etc...
December 1, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29196228/factors-related-to-skeletal-relapse-in-the-two-jaw-surgery-treatment-of-mandibular-prognathism
#13
Kwei-Jing Chen, Michael Yuan-Chien Chen, Jung-Hsuan Cheng, Chun-Ming Chen, Yu-Chuan Tseng
This study identified factors contributing to skeletal relapse in the two-jaw surgery treatment of mandibular prognathism. A set of three standardized lateral cephalograms (T1: before surgery, T2: immediately after surgery, T3: final follow-up after surgery) were obtained from 35 patients. The surgical changes were defined as follows: postsurgical immediate change (T2-T1), postoperative stability (T3-T2) and the final surgical change (T3-T1). The occlusal plane and gonial angles were also measured. Relapse was defined as the reverse movements of the menton point (Me) and point A, with the null hypothesis stating that Me and point A do not significantly change at the postoperative stability (T3-T2)...
November 28, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29192847/acid-etching-technique-of-non-decalcified-bone-samples-for-visualizing-osteocyte-lacuno-canalicular-network-using-scanning-electron-microscope
#14
Tiina Lampi, Hannah Dekker, Chris M Ten Bruggenkate, Engelbert A J M Schulten, Jopi J W Mikkonen, Arto Koistinen, Arja M Kullaa
The aim of this study was to define the acid-etching technique for bone samples embedded in polymethyl metacrylate (PMMA) in order to visualize the osteocyte lacuno-canalicular network (LCN) for scanning electron microscopy (SEM). Human jaw bone tissue samples (N = 18) were collected from the study population consisting of patients having received dental implant surgery. After collection, the bone samples were fixed in 70% ethanol and non-decalcified samples embedded routinely into polymethyl metacrylate (PMMA)...
December 1, 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/29192633/pattern-of-maxillofacial-surgical-conditions-in-north-central-nigeria-a-5-year-experience-of-an-indigenous-surgical-mission
#15
Seidu A Bello, Timothy Osodin, Ifeoluwa Oketade, Alwel-Brown Ibikari, Nosa Ighile, Deborah J Enebong, Paul Ekpa
BACKGROUND: Several publications have presented pattern of maxillofacial surgical conditions based on data from hospital-based studies. The objective of this study is to present the spectrum of maxillofacial surgical conditions from the perspective of a community study. METHODS: This is a prospective study of all patients seen and treated from 2011 to 2016. The information obtained included the biodata, clinical history of the disease conditions, radiological result, histopathologic result, diagnosis, and treatment records...
October 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29192423/bisphosphonates-for-paget-s-disease-of-bone-in-adults
#16
REVIEW
Luis Corral-Gudino, Adrian Jh Tan, Javier Del Pino-Montes, Stuart H Ralston
BACKGROUND: Bisphosphonates are considered to be the treatment of choice for people with Paget's disease of bone. However, the effects of bisphosphonates on patient-centred outcomes have not been extensively studied. There are insufficient data to determine whether reducing and maintaining biochemical markers of bone turnover to within the normal range improves quality of life and reduces the risk of complications. OBJECTIVES: To assess the benefits and harms of bisphosphonates for adult patients with Paget's disease of bone...
December 1, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29191501/immunoprecipitation-high-performance-liquid-chromatographic-analysis-of-healing-process-in-chronic-suppurative-osteomyelitis-of-the-jaw
#17
Soung Min Kim, Mi Young Eo, Yun Ju Cho, Yeon Sook Kim, Suk Keun Lee
PURPOSE: Chronic suppurative osteomyelitis (CSO) of the jaw is one of the most difficult infectious diseases to manage, because it causes progressive bony destruction and is associated with bacterial inhabitation of the sequestra. A combination of antibiotic therapy and surgical debridement is often used to treat CSO. Nevertheless, various systemic conditions can lead to life-threatening complications. METHODS: The present study aimed to explore the wound healing progress in 16 cases of CSO through protein expression analysis of postoperative exudates (POE) that were collected 6 h, 1 day, and 2 days after saucerization and/or decortication...
October 27, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29188647/-experimental-study-on-accelerated-healing-of-jaw-fracture-using-gelatin-sponge-compound-growth-factor
#18
Tang Yanfeng, Chen Jianlin, Zhou Yunbiao
OBJECTIVE: To explore the role and mechanism of drug delivery systems using growth factor combined with gelatin sponge on accelerating the healing of jaw fracture and to seek better treatment of accelerating the maxillofacial fracture. METHODS: About 100 μg recombinant human bone morphogenetic protein (BMP)-2 was completely dissolved in 1 mL recombinant bovine basic fibroblast growth factor (bFGF), and the solution (40 μL) was dropped in gelatin sponge (0.5 cm×0...
October 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29187222/unusual-presentation-of-plasmablastic-lymphoma-involving-ovarian-mature-cystic-teratoma-a-case-report
#19
Ita Hadžisejdić, Emina Babarović, Luka Vranić, Antica Duletić Načinović, Ksenija Lučin, Maja Krašević, Nives Jonjić
BACKGROUND: Plasmablastic lymphoma (PBL) is relatively new clinical entity described as a distinct subtype of diffuse large B-cell lymphoma (DLBCL). It is characterized by its aggressive nature and proliferation of large neoplastic cells resembling immunoblasts including cells with more obvious plasmacytic differentiation. In this case report, we describe an unexpected finding of PBL associated with a mature cystic teratoma of the ovary in a young immune competent woman. CASE PRESENTATION: A 19-year old woman was admitted to the hospital with generalized lymphadenopathy, a pelvic tumor mass measuring 35 × 30 cm and a 4 cm lump in her right breast...
November 29, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/29184726/occlusal-plane-altering-2-jaw-surgery-based-on-the-clockwised-rotational-surgery-first-orthognathic-approach
#20
Jong Woo Choi, Woo Shik Jeong
Supplemental Digital Content is available in the text.
October 2017: Plastic and Reconstructive Surgery. Global Open
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