keyword
MENU ▼
Read by QxMD icon Read
search

Menopause epilepsy

keyword
https://www.readbyqxmd.com/read/27678205/women-with-epilepsy-clinically-relevant-issues
#1
S Bangar, Abhishek Shastri, Hany El-Sayeh, Andrea E Cavanna
Women with epilepsy (WWE) face specific challenges throughout their lifespan due to the effects of seizures and antiepileptic drugs on hormonal function, potentially affecting both sexual and reproductive health. This review article addresses the most common issues of practical relevance to clinicians treating WWE: epidemiology and clinical presentations (including catamenial epilepsy), contraception, reproductive and sexual dysfunction, pregnancy, lactation, menopause-related issues (including bone health), and mental health aspects...
July 2016: Functional Neurology
https://www.readbyqxmd.com/read/27428288/women-with-epilepsy-clinically-relevant-issues
#2
S Bangar, Abhishek Shastri, Hany El-Sayeh, Andrea E Cavanna
Women with epilepsy (WWE) face specific challenges throughout their lifespan due to the effects of seizures and antiepileptic drugs on hormonal function, potentially affecting both sexual and reproductive health. This review article addresses the most common issues of practical relevance to clinicians treating WWE: epidemiology and clinical presentations (including catamenial epilepsy), contraception, reproductive and sexual dysfunction, pregnancy, lactation, menopause-related issues (including bone health), and mental health aspects...
July 18, 2016: Functional Neurology
https://www.readbyqxmd.com/read/27424276/the-neuroendocrine-basis-of-sex-differences-in-epilepsy
#3
Doodipala Samba Reddy
Epilepsy affects people of all ages and both genders. Sex differences are well known in epilepsy. Seizure susceptibility and the incidence of epilepsy are generally higher in men than women. In addition, there are gender-specific epilepsies such as catamenial epilepsy, a neuroendocrine condition in which seizures are most often clustered around the perimenstrual or periovulatory period in adult women with epilepsy. Changes in seizure sensitivity are also evident at puberty, pregnancy, and menopause. Sex differences in seizure susceptibility and resistance to antiseizure drugs can be studied in experimental models...
July 13, 2016: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/27412920/update-on-management-of-epilepsy-in-women-for-the-non-neurologist
#4
REVIEW
Inuka Kishara Gooneratne, Sunil Wimalaratna
Epilepsy is a common neurological disorder, prevalent in about 1% of the population. Almost half of the patients with epilepsy are women. Epilepsy and antiepileptic drugs can affect each aspect of the female human life cycle which includes menstrual cycle, contraception, fertility, conception, pregnancy and menopause. The interplay of the female hormonal state and epilepsy is complex and has to be taken in to consideration when managing their epilepsy. This review focuses on the management of women with epilepsy related to their role in reproduction...
September 2016: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/27176879/drug-resistant-focal-epilepsy-in-women-of-childbearing-age-reproduction-and-the-effect-of-epilepsy-surgery
#5
Rachel R Fabris, Teresa Griffin Cascino, Jay Mandrekar, W Richard Marsh, Frederic B Meyer, Gregory D Cascino
OBJECTIVE: Women with epilepsy (WWE) have lower birth rates than expected. The reasons for this are multifactorial and involve a complex interaction between reproductive endocrine and psychosocial factors. The effect of epilepsy surgery on reproduction in women with drug-resistant focal epilepsy has not previously been studied. METHODS: Adult women of childbearing age (18-45years old) with drug-resistant focal epilepsy who had undergone a focal cortical resection between 1997 and 2008 at the Mayo Clinic in Rochester, MN were included in the study...
July 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27086987/issues-for-women-with-epilepsy
#6
REVIEW
Naymeé J Vélez-Ruiz, Page B Pennell
Epilepsy and antiepileptic drugs affect the menstrual cycle, aspects of contraception, reproductive health, pregnancy, and menopause through alteration of sex steroid hormone pathways. Sex steroid hormones often have an effect on seizure frequency and may alter the level of some antiepileptic drugs. Approximately one-third of women experience an increase in perimenstrual and/or periovulatory seizure frequency. Some women experience an increase in seizure frequency during pregnancy. Balancing maternal seizure control and the risk of congenital malformations associated with fetal antiepileptic drug exposure may be challenging...
May 2016: Neurologic Clinics
https://www.readbyqxmd.com/read/26335277/the-impact-of-gonadal-hormones-on-the-expression-of-human-neurological-disorders
#7
Hyman M Schipper
The effects of gonadal steroids on neurological well-being and disease constitute a rich and rapidly expanding area of basic and clinical neuroscience. Gonadal hormones exert potent effects on monoaminergic, cholinergic and peptidergic pathways as well as neurosteroidogenesis which, in turn, impact normal brain organization and function. A spectrum of human neurological conditions are influenced by hormonal fluctuations associated with the menstrual cycle, pregnancy, the menopause and use of oral contraceptives...
2016: Neuroendocrinology
https://www.readbyqxmd.com/read/26288286/-algorithms-of-using-valproic-acid-drugs-in-women
#8
REVIEW
P N Vlasov
Characteristics of using valproic acid drugs in women, from puberty to menopause period, are reviewed. Based on initial treatment efficacy, type of epileptic seizures and a form of epilepsy, the author emphasizes the practical use of valproates during pregnancy in dependence on the situation. Several scenarios of pregnancy course and possible treatment tactics are presented.
2015: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/26001664/comparison-of-precipitating-factors-for-mania-and-partial-seizures-indicative-of-shared-pathophysiology
#9
REVIEW
Emmanuelle C S Bostock, Kenneth C Kirkby, Michael I Garry, Bruce V M Taylor
OBJECTIVES: Mania in bipolar disorder (BD) and partial (focal) seizures (PS) arising from the temporal lobes, have a number of similarities. Typically, a chronic course of the disorders is punctuated by acute illness episodes. Common features of episodes may include sensory, perceptual, cognitive and affective changes. Both respond to anticonvulsant treatment. Common mechanisms imputed include neurotransmitters and kindling processes. Further investigation may improve understanding of the occurrence of both mania and PS, casting light on the relevance of temporal lobe mediated processes and pathology...
September 1, 2015: Journal of Affective Disorders
https://www.readbyqxmd.com/read/25561381/folate-use-in-women-with-epilepsy-predictors-of-adherence-in-a-specialized-tertiary-outclinic
#10
Valmir Passarelli, Nathália Stela Visoná de Figueiredo, Débora Bartzen Moraes Angst, Meire Argentoni Baldocchi, Maria Sheila Guimarães Rocha
PURPOSE OF THE STUDY: The aims of this study were to determine the percentage of women with epilepsy (WWE) taking folic acid (FA) in an outpatient epilepsy tertiary hospital at São Paulo, Brazil, and to identify the possible predictors of adherence. METHOD: Five hundred seventy-six medical records of patients followed in our service were reviewed. Sixty-six WWE using antiepileptic drugs with age between 16 and 52, sexually active but not in menopausal period, not pregnant, and not sterilized or with vasectomized partners underwent direct interviews with a prestructured questionnaire...
February 2015: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/25218046/raloxifene-protects-against-seizures-and-neurodegeneration-in-a-mouse-model-mimicking-epilepsy-in-postmenopausal-woman
#11
F H Pottoo, M Bhowmik, D Vohora
Epilepsy in menopausal women presents several challenges in the treatment including an increased risk of seizures due to hormone replacement therapy. We investigated the hypothesis if raloxifene, a selective oestrogen receptor modulator, could be employed to prevent behavioural seizures and morphological alterations in a mouse model mimicking epilepsy in postmenopausal women. Female mice were made ovotoxic by treatment with 4-vinylcyclohexene diepoxide (VCD) to mimic a postmenopausal state. They were then subjected to kainic acid (KA)-induced seizures and neurotoxicity, as assessed by microscopic examination of hippocampus, relevant to human temporal lobe epilepsy...
December 18, 2014: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/25124647/weight-and-fat-distribution-in-patients-taking-valproate-a-valproate-discordant-gender-matched-twin-and-sibling-pair-study
#12
Sandra J Petty, Susan Kantor, Kate M Lawrence, Samuel F Berkovic, Marnie Collins, Keith D Hill, Joanna Makovey, Philip N Sambrook, Terence J O'Brien, John D Wark
OBJECTIVES: Chronic treatment with valproate (VPA) is commonly associated with weight gain, which potentially has important health implications, in particular increased central fat distribution. We utilized a VPA-discordant same-sex, twin and matched sibling pair study design to primarily examine for differences in fat distribution between patients with epilepsy treated with VPA compared to their matched twin or sibling control. Weight, blood pressure, and leptin levels were assessed...
October 2014: Epilepsia
https://www.readbyqxmd.com/read/25079452/epilepsy-and-menopause-potential-implications-for-pharmacotherapy
#13
REVIEW
Olafur Sveinsson, Torbjörn Tomson
Being a woman with epilepsy is not the same as being a man with the disease. There is a complex multidirectional interaction between sex hormones, seizures and antiepileptic drugs (AEDs) with gender-specific implications. Estrogen can be a potent proconvulsant, whereas progesterone is an anticonvulsant in experimental models. It is well established that women with epilepsy can have changes in seizure propensity related to their menstrual cycle (catamenial epilepsy). There is good evidence that the gonadotropin-releasing hormone cell population in the hypothalamus can be affected by seizures originating in the limbic system, possibly leading to anovulatory menses, possibly contributing to lower fertility, and earlier menopause among women with epilepsy...
September 2014: Drugs & Aging
https://www.readbyqxmd.com/read/24653613/prevalence-of-gingival-enlargement-in-karnataka-school-going-children
#14
K Bala Krishna, P Krishnam Raju, Radha Raani Chitturi, G Smitha, S Vijai, B V V Srinivas
BACKGROUND: Periodontal diseases affect more people all over the world than dental caries. Increase in size of gingiva is known as gingival hyperplasia or gingival enlargement. Gingival swelling is almost universally the result of Fluid accumulation within the tissues. Enlargement and even aesthetically disfiguring over growth of the gingival tissue, is also a common finding of leukemia, scurvy and subjects undergoing the hormonal changes of puberty, pregnancy, menopause and drugs. MATERIALS & METHODS: A sample size of 1500 was taken...
February 2014: Journal of International Oral Health: JIOH
https://www.readbyqxmd.com/read/24386664/effect-of-brivaracetam-400-mg-day-on-the-pharmacokinetics-and-pharmacodynamics-of-a-combination-oral-contraceptive-in-healthy-women
#15
RANDOMIZED CONTROLLED TRIAL
Armel Stockis, Paul Rolan
Brivaracetam is a high-affinity synaptic vesicle protein 2A ligand, in Phase III clinical development for epilepsy. This study assessed the effect of brivaracetam 400 mg/day on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive (OC) containing 30 µg ethinylestradiol and 150 µg levonorgestrel, in healthy pre-menopausal women. This open-label, single-center, randomized, two-way crossover, multiple oral dose study (N01080) included two consecutive 28-day cycles without (control) or with brivaracetam (test), and a 28-day follow-up...
December 2013: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/24146518/african-mistletoes-loranthaceae-ethnopharmacology-chemistry-and-medicinal-values-an-update
#16
REVIEW
Simeon K Adesina, H C Illoh, Imoh I Johnny, Imoh E Jacobs
Mistletoes of the Loranthaceae and Viscaceae are hemiparasitic plants and their preparations in the form of injectable extracts, infusions, tinctures, fluid extracts or tea bags are widely used in various cultures in almost every continent to treat or manage various health problems including hypertension, diabetes mellitus, inflammatory conditions, irregular menstruations, menopause, epilepsy, arthritis, cancer, etc. The medicinal values of some species of Mistletoes (Loranthaceae) growing in the West African sub-region have been reviewed along with some considerations of their chemistries and local uses...
2013: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/23377355/women-epilepsy-and-anti-epileptic-drugs
#17
Sonia A Khan
Epilepsy is a chronic disease interlinked with many aspects of a womans life. The objective for this syllabus is to review these aspects and update physicians treating epileptic women on the recent management recommendations in this population. Epilepsy is more common in males except in adolescence and the elderly. Certain epileptic syndromes are exclusively seen in females such as Rett syndrome, Aicardi syndrome and periventricular nodular heterotopia. Female sex hormones may alter seizure threshold in epileptic women and form the basis for catamenial epilepsy...
April 2004: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/23120788/-lamotrigine-in-treatment-of-women-with-epilepsy
#18
REVIEW
P N Vlasov, D V Dranko, O V Agranovich
The paper presents the review of literature on the age aspect of using lamotrigine in pubertal period, in women of reproductive age, during pregnancy and lactation and in climacteric period. Special attention is drawn to the low teratogenic potential of this drug used as a monotherapy. It has been concluded that lamotrigine is expedient to be used in treatment of partial and generalized epilepsy in women.
2011: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/22527036/pure-menstrual-migraine-with-sensory-aura-a-case-report
#19
Jiann-Jy Chen, Yung-Chu Hsu, Dem-Lion Chen
Hormonal changes related to the menstrual cycle have a great impact on migraines in women. Menstrual migraine attacks are almost invariably without aura. Categorizing migraines into menstrual or non-menstrual types is one way to stratify migraines without aura according to the appendix criteria of the International Classification of Headache Disorders. We report a peri-menopausal woman whose sensory aura exclusively heralded menstrual migraine. A 51-year-old woman had suffered from monthly episodic headaches since the age of 46...
July 2012: Journal of Headache and Pain
https://www.readbyqxmd.com/read/22465884/management-of-women-with-epilepsy-practical-issues-faced-when-dealing-with-women-with-epilepsy
#20
REVIEW
Fawzi A Babtain
Epilepsy is commonly encountered in neurology practice, affecting more than 50 million people worldwide, according to the World Health Organization reports. Management of women with epilepsy requires attention to some considerations including the hormonal changes and its impact on epilepsy, the interaction between oral contraceptives and antiepileptic drugs (AEDs), pregnancy, and the potential teratogenic risk associated with AEDs use during that period. Similarly, the effect of AEDs on bone health should always be considered, and measures should be taken to reduce the risk of osteoporosis given the fact that women in their menopause are at increased risk...
April 2012: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
keyword
keyword
4711
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"