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https://www.readbyqxmd.com/read/27899986/metastasis-of-renal-cell-carcinoma-to-the-parathyroid-gland-16-years-after-radical-nephrectomy-a-case-report
#1
Liborio Torregrossa, Maria Isabella Rotondo, Andrea Cacciato Insilla, David Galleri, Federica Guidoccio, Paolo Miccoli, Virginia A Livolsi, Fulvio Basolo
Renal cell carcinoma (RCC) has a high metastatic potential, and most commonly metastasizes via the bloodstream, although lymphatic metastases also occur. RCC is well-known for its propensity to metastasize to unusual sites, and late metastasis, even after a number of years, is common. The occurrence of RCC metastasis to the head and neck region is uncommon, and occurs primarily in the thyroid gland and in patients with widespread dissemination. Involvement of the parathyroid gland in metastatic carcinoma is extremely rare...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27882431/diagnostic-value-of-conventional-chest-radiography-in-intrathoracic-goiters-retrospective-analysis-of-2570-patients
#2
Fares Benmiloud, Michel Grino, Charles Oliver, Anne Denizot
PURPOSE: Since intrathoracic goiters (IG), either cervico-mediastinal goiters (CMGs) or mediastinal nodules (MNs), can lead to sternotomies and/or evitable reoperations, their detection is mandatory before thyroid surgery. A systematic screening by CT scan or MRI is not conceivable because of their expensiveness. We tested if conventional chest radiography (CCR) could remain a good screening tool for IG before thyroid surgery. METHODS: In this retrospective study (2554 patients), CCR usefulness was evaluated in relation with patients' complaints, clinical examination, neck US, and anatomical and surgical findings...
November 24, 2016: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/27867862/intermittent-neural-monitoring-of-the-recurrent-laryngeal-nerve-in-surgery-for-recurrent-goiter
#3
REVIEW
Beata Wojtczak, Marcin Barczyński
Reoperative thyroid surgery is still challenging even for skilled surgeons, and is associated with a higher incidence of complications, such as hypoparathyroidism and recurrent laryngeal nerve (RLN) palsy. Displacement of the RLN, scar tissue from previous neck surgery and difficulty in maintaining good hemostasis are risk factors in reoperations. The prevalence of RLN injury in reoperative thyroid surgery ranges as high as 12.5% for transient injury and up to 3.8% for permanent injury. Bilateral paresis can also occur during reoperations, and is a dangerous complication influencing the quality of life, sometimes requiring tracheostomy...
October 2016: Gland Surgery
https://www.readbyqxmd.com/read/27819641/an-unwonted-clinicopathological-subtype-of-thyroid-primary-lymphoma
#4
Mihai Radu Diaconescu, Ioan Costea, Mihai Glod, Smaranda Diaconescu
Primary thyroid lymphomas account for less than 5% of all thyroid malignancies and the majority of cases concern non- Hodgkin's lymphoma of B and T-cell origin as well as Hodgkin's lymphoma. Mucosa-associated lymphoid tissue (MALT) lymphoma are a relatively recently described subset of low grade B-cell non-Hodgkin's lymphoma representing between 6 and 27% of the patients with thyroid lymphomas. These cases occur usually in patients with Hashimoto's thyroiditis having a long indolent course and delayed diagnosis, actually benefit from several therapeutic opportunities among them even surgery and a favorable prognostic...
2016: Chirurgia
https://www.readbyqxmd.com/read/27818960/vocal-fold-mobility-alteration-reversed-after-thyroidectomy
#5
Aline Paterno Miazaki, Vergilius José Furtado Araújo-Filho, Lenine Garcia Brandão, Vergilius José Furtado de Araujo-Neto, Leandro Luongo Matos, Claudio Roberto Cernea
The involvement of the inferior or recurrent laryngeal nerve (RLN) in mobility derangement of the vocal folds occurs more frequently due to thyroid malignancy invasion. Although uncommon, the same derangement, which is caused by benign thyroid entities, is also described and reverts to normality after a thyroidectomy in up to 89% of cases. In these cases, the pathogenesis of the vocal cord mobility disturbance is attributed to the direct compression of the RLN by massive thyroid enlargement. The authors describe three cases of patients presenting unilateral vocal cord palsy, which, before surgery, was diagnosed by laryngoscopy concomitantly with large and compressive goiter...
July 2016: Autopsy & case reports
https://www.readbyqxmd.com/read/27809694/low-elasticity-of-thyroid-nodules-at-ultrasound-elastography-is-correlated-with-malignancy-degree-of-fibrosis-and-high-expression-of-galectin-3-and-fibronectin-1
#6
Teresa Rago, Maria Scutari, Valeria Loiacono, Ferruccio Santini, Massimo Tonacchera, Liborio Torregrossa, Riccardo Giannini, Nicla Borrelli, Agnese Proietti, Fulvio Basolo, Paolo Miccoli, Paolo Piaggi, Francesco Latrofa, Paolo Vitti
BACKGROUND: Thyroid ultrasound elastography (US elastography) provides an estimation of tissue stiffness and is helpful to differentiate malignant from benign lesions. Tissue proprieties and molecules causing stiffness are not established. The aim of the study was to correlate US elastography findings with tissue properties in thyroid nodules. METHODS: 115 thyroid nodules from 112 patients who underwent surgery for the presence of of Thy 3 (indeterminate) cytology (n=67), Thy 4-5 (suspicious-indicative of carcinoma) cytology (n= 47) or large goiter in the presence of Thy 2 cytology (n= 1) and suspicious US features were examined by US elastography...
November 3, 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27806818/delayed-presentation-of-forgotten-thyroid-goiter-25-years-after-thyroidectomy
#7
Fazal Wahab Khan, Ayesha Muhammad, Mohsin Abbas, Syed Usman Bin Mahmood, Benish Fatima, Saulat H Fatimi
Forgotten goiter is a rare occurrence (2 - 16% of retrosternal thyroid cases) that depicts recurrence of retrosternal thyroid mass due to growth of remnant thyroid tissue overlooked during an initial thyroidectomy. The patient is a 59-year female who presented with dyspnea and stridor 25 years after total thyroidectomy. She was diagnosed as having a mediastinal mass on radiographic imaging. There were only localized pressure symptoms due to mass effect. The mass was excised employing an extra-cervical approach and using a partial sternotomy...
October 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27802347/ret-ptc-rearrangements-are-associated-with-elevated-postoperative-tsh-levels-and-multifocal-lesions-in-papillary-thyroid-cancer-without-concomitant-thyroid-benign-disease
#8
Xuan Su, Caiyun He, Jiangjun Ma, Tao Tang, Xiao Zhang, Zulu Ye, Yakang Long, Qiong Shao, Jianyong Shao, Ankui Yang
RET/PTC rearrangements, resulting in aberrant activity of the RET protein tyrosine kinase receptor, occur exclusively in papillary thyroid cancer (PTC). In this study, we examined the association between RET/PTC rearrangements and thyroid hormone homeostasis, and explored whether concomitant diseases such as nodular goiter and Hashimoto's thyroiditis influenced this association. A total of 114 patients diagnosed with PTC were enrolled in this study. Thyroid hormone levels, clinicopathological parameters and lifestyle were obtained through medical records and surgical pathology reports...
2016: PloS One
https://www.readbyqxmd.com/read/27795799/-thyroid-abscess-revealing-graves-basedow-disease-about-a-case-and-review-of-the-literature
#9
Meriem Chenguir, Hajar Souldi, Fatima Zahra Loufad, Sami Rouadi, Reda Abada, Mohamed Roubal, Mohamed Mahtar
Thyroid abscess is a very rare clinical entity. It accounts for 0.1% of the surgical pathologies of the thyroid gland. The anatomical and physiological characteristics of the gland give it resistance to pathogens. Streptococcal and Staphylococcal are the most common. Tuberculosis is rarely reported in the literature. The occurrence of infection associated with toxic goiter is exceptional. The authors report a rare case of a 22-year-old young patient with thyroid abscess revealing a toxic goitre. He presented to our otorhinolaryngology emergency unit with anterior cervical swelling, slightly lateralized to the left, moving on swallowing, associated with hemoptysis, signs of thyroid dysfunction, fever, night sweats...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27784321/horner-s-syndrome-an-unusual-complication-of-thyroidectomy-a-case-report
#10
Sanjeewa A Seneviratne, Dewamuni S Kumara, Akram M P Drahaman
BACKGROUND: Horner's syndrome is a very rare complication following surgery of the thyroid gland with only a handful of cases reported in the literature. Exact pathophysiology of post-thyroidectomy Horner's syndrome is not fully understood, and once diagnosed, management remains mostly conservative. CASE PRESENTATION: A 36-year-old Sri Lankan Sinhalese woman developed unilateral partial ptosis with enophthalmos and myosis one week after total thyroidectomy for a benign multinodular goiter...
October 26, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27703381/an-evaluation-of-the-diagnostic-efficacy-of-fine-needle-aspiration-biopsy-in-patients-operated-for-a-thyroid-nodular-goiter
#11
Dariusz Janczak, Wiktor Pawlowski, Tadeusz Dorobisz, Dawid Janczak, Karolina Dorobisz, Michal Leśniak, Agnieszka Ziomek, Mariusz Chabowski
BACKGROUND: Thyroid cancer (TC) comprises 1% of all carcinomas and is the most common malignancy of the endocrine system. The disease is more common in women, with its peak morbidity observed in 40-50-year-old patients. The main risk factors include radiation, iodine deficiency, hereditary background, and genetic mutations. Among all diagnosed thyroid nodules, 5%-30% will evolve into cancer. The gold-standard procedure in the preoperative evaluation of a nodular goiter, apart from ultrasonography, is fine needle aspiration (FNA) biopsy...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27687679/anatomical-approach-to-surgery-for-intrathoracic-goiter
#12
Michael Vaiman, Inessa Bekerman
The anatomical approach to the intrathoracic goiter (ITG) was used to understand its etiology and to rationalize surgical technique of thyroidectomy. For a retrospective chart review, we selected cases of multinodular goiter with totally ITGs (n = 69; M 29, F 40), while 916 cases with cervical goiter were used for comparison. The topography of the thyroid gland was assessed against the tracheal rings and against the vertebrae. The regional anatomy of the thoracic inlet was assessed by its bony margins and the relations of structures traversing the area...
September 29, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27686396/de-quervain-s-thyroiditis-a-review-of-experience-with-surgery
#13
Rohit Ranganath, Manish A Shaha, Bin Xu, Jocelyn Migliacci, Ronald Ghossein, Ashok R Shaha
BACKGROUND: de Quervain's thyroiditis is an inflammatory condition of the thyroid mostly treated medically, rarely requiring surgical treatment. We intend to review the surgical experience with de Quervain's thyroiditis at a tertiary cancer center over a period of 22years. METHODS: A retrospective review of medical records from 1992 to 2014 at a tertiary cancer center was performed and all patients with a histopathological diagnosis of de Quervain's thyroiditis were included...
August 18, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27659020/influence-of-change-in-surgical-practice-for-benign-thyroid-disease-on-postsurgical-outcome-single-center-experience-in-1400-patients
#14
Urte Kunz-Zurbuchen, Heinz Johannes Buhr, Hubert G Hotz, Martin E Kreis, Kai S Lehmann
PURPOSE: To evaluate the rate of surgical complications during the change from subtotal resection to hemithyroidectomy or thyroidectomy over a period of 17 years. METHODS: All operations for benign goiter at our hospital were analyzed for the periods 1996-2002 (Group 1) and 2003-2012 (Group 2). The groups were compared for recurrent laryngeal nerve damage, hypocalcemia, and other surgical complications directly postoperatively. RESULTS: In total, 1462 patients were operated on for goiter between 1996 and 2012...
September 19, 2016: Asian Journal of Surgery
https://www.readbyqxmd.com/read/27628225/-the-choice-of-surgery-in-patients-with-diffuse-toxic-goiter
#15
A N Vachev, E V Frolova, D R Sakhipov, N V Morkovskikh
AIM: to define clear individual indications for different operations for diffuse toxic goiter by research of immunological markers of thyrotoxicosis recurrence probability. MATERIAL AND METHODS: Long-term results of survey and treatment of 215 patients with diffuse toxic goiter are presented. Patients were divided into 2 groups. The 1st group consisted of 31 patienrs who underwent conventional partial thyroidectomy. Group 2 included 184 patients. They were divided into 2 subgroups depending on type of surgery...
2016: Khirurgiia
https://www.readbyqxmd.com/read/27612033/fluorine-18-fluorocholine-pet-ct-localizes-hyperparathyroidism-in-patients-with-inconclusive-conventional-imaging-a-multicenter-study-from-the-netherlands
#16
Wouter P Kluijfhout, Wessel M C M Vorselaars, Sandra A M van den Berk, Menno R Vriens, Inne H M Borel Rinkes, Gerlof D Valk, Thijs van Dalen, John M H de Klerk, Bart de Keizer
BACKGROUND: Several reports have shown good performance of fluorine-18 fluorocholine (F-FCH) PET-computed tomography (CT) for parathyroid localization, although overall evidence remains scarce. We collected data from three institutions in the Netherlands and investigated the performance of F-FCH PET-CT as a second-line imaging modality. MATERIALS AND METHODS: We performed a retrospective review of all patients at least 18 years who underwent F-FCH PET-CT for biochemically proven hyperparathyroidism (HPT) and inconclusive ultrasound and sestamibi scintigraphy...
September 8, 2016: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/27584011/intraoperative-nerve-monitoring-during-thyroid-surgery
#17
Ivy H Gardner, Gerard M Doherty, David McAneny
PURPOSE OF REVIEW: Laryngeal nerve injury, resulting in speech and swallowing dysfunction, is a feared complication of thyroid operations. Routine visualization of the recurrent laryngeal nerve (RLN) has decreased the likelihood of nerve injury, and intraoperative nerve monitoring has been applied in the hope of further enhancing safety. RECENT FINDINGS: There is conflicting evidence about the value of nerve monitoring during thyroid operations, despite ample research...
October 2016: Current Opinion in Endocrinology, Diabetes, and Obesity
https://www.readbyqxmd.com/read/27521067/2016-american-thyroid-association-guidelines-for-diagnosis-and-management-of-hyperthyroidism-and-other-causes-of-thyrotoxicosis
#18
Douglas S Ross, Henry B Burch, David S Cooper, M Carol Greenlee, Peter Laurberg, Ana Luiza Maia, Scott A Rivkees, Mary Samuels, Julie Ann Sosa, Marius N Stan, Martin A Walter
BACKGROUND: Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies. Appropriate treatment requires an accurate diagnosis and is influenced by coexisting medical conditions and patient preference. This document describes evidence-based clinical guidelines for the management of thyrotoxicosis that would be useful to generalist and subspecialty physicians and others providing care for patients with this condition. METHODS: The American Thyroid Association (ATA) previously cosponsored guidelines for the management of thyrotoxicosis that were published in 2011...
October 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27504993/laser-radiofrequency-and-ethanol-ablation-for-the-management-of-thyroid-nodules
#19
Enrico Papini, Rinaldo Gugliemi, Claudio Maurizio Pacella
PURPOSE OF REVIEW: The majority of benign thyroid nodules are nearly asymptomatic, remain stable in size, and do not require treatment. However, a minority of patients with growing nodules may complain of local symptoms or have cosmetic concerns, and thus seek surgical consultation. RECENT FINDINGS: The timely use of ultrasound-guided minimally invasive procedures can change the natural history of benign enlarging thyroid nodules. The procedures produce persistent shrinkage of thyroid nodules and are associated with improvement of local symptoms...
October 2016: Current Opinion in Endocrinology, Diabetes, and Obesity
https://www.readbyqxmd.com/read/27504462/an-uncommon-association-of-familial-partial-lipodystrophy-dilated-cardiomyopathy-and-conduction-system-disease
#20
Ragesh Panikkath, Deepa Panikkath, S Sanchez-Iglesias, D Araujo-Vilar, Joaquin Lado-Abeal
A 46-year-old African American woman presented with severe respiratory distress requiring intubation and was diagnosed with nonischemic cardiomyopathy. She had the typical phenotype of familial partial lipodystrophy 2 (FPLD2). Sequence analysis of LMNA gene showed a heterozygous missense mutation at exon 8 (c.1444C>T) causing amino acid change, p.R482W. She later developed severe coronary artery disease requiring multiple percutaneous coronary interventions and coronary artery bypass surgery. She was later diagnosed with diabetes, primary hyperparathyroidism, and euthyroid multinodular goiter...
July 2016: Journal of Investigative Medicine High Impact Case Reports
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