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Echocardiographic

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https://www.readbyqxmd.com/read/29453682/persistent-pulmonary-hypertension-and-histologic-chorioamnionitis-in-preterm-infants-controlled-study
#1
N Katz, Y Bar-Or, A Raucher-Sterrnfeld, A Tamir, D Kohelet
Persistent pulmonary hypertension (PPHN) of the newborn is one of the most challenging acute disorders of postnatal transition with substantial morbidity and mortality. The aim of the study was to find if there is an association between persistent pulmonary hypertension and histologic chorioamnionitis in preterm infants. 27 preterm infants with echocardiographic evidence of PPHN within the first 3 days of life were eligible for the study. A matched control group of 27 patients was chosen according to gestational age, date of birth, and gender...
February 16, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29453593/risk-marker-profiles-in-patients-treated-with-percutaneous-septal-ablation-for-symptomatic-hypertrophic-obstructive-cardiomyopathy
#2
Amelie Burghardt, Frank van Buuren, Zisis Dimitriadis, Tim Grübbel, Hubert Seggewiss, Smita Scholtz, Dieter Horstkotte, Lothar Faber
BACKGROUND AND STUDY OBJECTIVE: Different studies have shown a good long-term survival with improvement of symptoms and hemodynamics after percutaneous septal ablation (PTSMA), similar to myectomy considered to be the therapeutic "gold standard" for symptomatic hypertrophic obstructive cardiomyopathy (HOCM). Furthermore, desobliteration of left ventricular (LV) outflow may modify features of the disease considered to be risk-relevant, such as magnitude of LV hypertrophy, outflow gradient, and left atrial (LA) size...
February 16, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29453394/experimental-modelling-of-cardiac-pressure-overload-hypertrophy-modified-technique-for-precise-reproducible-safe-and-easy-aortic-arch-banding-debanding-in-mice
#3
David Merino, Aritz Gil, Jenny Gómez, Luis Ruiz, Miguel Llano, Raquel García, María A Hurlé, J Francisco Nistal
Pressure overload left ventricular hypertrophy is a known precursor of heart failure with ominous prognosis. The development of experimental models that reproduce this phenomenon is instrumental for the advancement in our understanding of its pathophysiology. The gold standard of these models is the controlled constriction of the mid aortic arch in mice according to Rockman's technique (RT). We developed a modified technique that allows individualized and fully controlled constriction of the aorta, improves efficiency and generates a reproducible stenosis that is technically easy to perform and release...
February 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29452808/norepinephrine-exerts-an-inotropic-effect-during-the-early-phase-of-human-septic-shock
#4
O Hamzaoui, M Jozwiak, T Geffriaud, B Sztrymf, D Prat, F Jacobs, X Monnet, P Trouiller, C Richard, J L Teboul
BACKGROUND: We conducted this study to investigate whether norepinephrine increases cardiac contractility when administered during the early phase of septic shock. METHODS: We studied 38 patients with septic shock who had been resuscitated for <3 h and whose mean arterial pressure (MAP) remained <65 mm Hg. Echocardiographic variables were obtained before (T 0 ) and after either initiation or an increase in the dose of a norepinephrine infusion to increase MAP to ≥ 65 mm Hg (T 1 )...
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29452581/prospective-observational-study-on-assessing-the-hemodynamic-relevance-of-patent-ductus-arteriosus-with-frequency-domain-near-infrared-spectroscopy
#5
Christoph E Schwarz, Antonio Preusche, Martin Wolf, Christian F Poets, Axel R Franz
BACKGROUND: What constitutes a hemodynamically relevant patent ductus arteriosus (hrPDA) in preterm infants is unclear. Different clinical and echocardiographic parameters are used, but a gold standard definition is lacking. Our objective was to evaluate associations between regional cerebral tissue oxygen saturation (rcStO 2 ), fraction of tissue oxygen extraction (rcFtO 2 E) measured by frequency domain near-infrared spectroscopy (fd-NIRS) and their correlation to echocardiographic, Doppler-ultrasound, and clinical parameters in preterm infants with and without a hrPDA...
February 16, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29452309/echocardiography-for-the-management-of-patients-with-biventricular-pacing-possible-roles-in-cardiac-resynchronization-therapy-implementation
#6
REVIEW
Emmanouil Poulidakis, Constantina Aggeli, Konstantinos Kappos, Antonis S Manolis, Skevos Sideris, Konstantinos Gatzoulis, Evangelos Oikonomou, Dimitrios Tousoulis
Cardiac Resynchronization Therapy (CRT) is an established therapeutic option for the subset of patients with heart failure (HF), reduced ejection fraction (EF) and dyssynchrony evidenced by electrocardiography. Benefit from CRT has been proven in many clinical trials, yet a sizeable proportion of these patients with wide QRS do not respond to this intervention, despite the updated practice guidelines. Several echocardiographic indices, targeting mechanical rather than electrical dyssynchrony, have been suggested to address this issue, but research so far has not succeeded in providing a single and simple measurement with adequate sensitivity and specificity for identification of responders...
February 13, 2018: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29451950/intrinsic-changes-of-left-ventricular-function-in-patients-with-beh%C3%A3-et-disease-and-comparison-according-to-systemic-disease-activity
#7
Byung Joo Sun, Jae-Hyeong Park, Su-Jin Yoo, Yunseon Park, Yeon Ju Kim, In Suk Lee, Jinhyun Kim, In Seol Yoo, Seung Cheol Shim, Seong Wook Kang, Jun-Hyung Kim, Jae-Hwan Lee, Si Wan Choi, Jin-Ok Jeong, In-Whan Seong
PURPOSE: Although cardiac manifestation of Behçet disease (BD) has been described in sporadic reports, its timely diagnosis remains difficult. The objective of this study was to describe early cardiac manifestations of BD. We also performed a comprehensive classification of systemic BD activity and compared their cardiac manifestations. METHODS: A prospective screening using speckle tracking echocardiography was performed in 85 patients with BD who had no history of heart disease...
February 16, 2018: Echocardiography
https://www.readbyqxmd.com/read/29451444/survival-and-prognostic-factors-in-cats-with-restrictive-cardiomyopathy-a-review-of-90-cases
#8
Chiara Locatelli, Danitza Pradelli, Giulia Campo, Ilaria Spalla, Alice Savarese, Paola G Brambilla, Claudio Bussadori
Objectives Large studies focusing on restrictive cardiomyopathy (RCM) in the cat are scarce. The aims of this retrospective study were to describe epidemiological characteristics and to analyse prognostic factors affecting survival in cats with RCM. Methods The clinical archives of the Gran Sasso Veterinary Clinic (Milan, Italy) and of the cardiology unit of the Department of Veterinary Medicine (University of Milan, Italy) from 1997-2015 were reviewed for all cats diagnosed with RCM based on an echocardiographic examination (left atrial/bi-atrial enlargement, normal left ventricle wall thickness, normal or mildly decreased systolic function and restrictive left ventricle filling pattern with pulsed Doppler echocardiography)...
February 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29449957/early-detection-of-myocardial-dysfunction-using-two-dimensional-speckle-tracking-echocardiography-in-a-young-cat-with-hypertrophic-cardiomyopathy
#9
Ryohei Suzuki, Yohei Mochizuki, Hiroki Yoshimatsu, Ayaka Niina, Takahiro Teshima, Hirotaka Matsumoto, Hidekazu Koyama
Case summary: A 5-month-old intact female Scottish Fold cat was presented for cardiac evaluation. Careful auscultation detected a slight systolic murmur (Levine I/VI). The findings of electrocardiography, thoracic radiography, non-invasive blood pressure measurements and conventional echocardiographic studies were unremarkable. However, two-dimensional speckle tracking echocardiography revealed abnormalities in myocardial deformations, including decreased early-to-late diastolic strain rate ratios in longitudinal, radial and circumferential directions, and deteriorated segmental systolic longitudinal strain...
January 2018: JFMS Open Reports
https://www.readbyqxmd.com/read/29449366/use-of-serum-transthyretin-as-a-prognostic-indicator-and-predictor-of-outcome-in-cardiac-amyloid-disease-associated-with-wild-type-transthyretin
#10
Jacquelyn L S Hanson, Marios Arvanitis, Clarissa M Koch, John L Berk, Frederick L Ruberg, Tatiana Prokaeva, Lawreen H Connors
BACKGROUND: Wild-type transthyretin amyloidosis (ATTRwt), an underappreciated cause of heart failure in older adults, is challenging to diagnose and monitor in the absence of validated, disease-specific biomarkers. We examined the prognostic use and survival association of serum TTR (transthyretin) concentration in ATTRwt. METHODS AND RESULTS: Patients with biopsy-proven ATTRwt were retrospectively identified. Serum TTR, cardiac biomarkers, and echocardiographic parameters were assessed at baseline and follow-up evaluations...
February 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29447430/aucubin-protects-against-pressure-overload-induced-cardiac-remodelling-via-%C3%AE-3-ar-nnos-cascades
#11
Qing-Qing Wu, Yang- Xiao, Ming-Xia Duan, Yuan Yuan, Xiao-Han Jiang, Zheng Yang, Hai-Han Liao, Wei Deng, Qi-Zhu Tang
BACKGROUND AND PURPOSE: Aucubin, the predominant component of Eucommia ulmoides Oliv., plays an indispensable role in regulating oxidative stress. Considering that oxidative stress has previously been demonstrated to contribute to acute and chronic myocardial injury, we tested the effects of aucubin on cardiac remodelling and heart failure. EXPERIMENTAL APPROACH: In the first set of experiments, H9c2 cardiomyocytes and neonatal rat cardiomyocytes pre-treated with aucubin (1, 3 10, 25, 50 μM) were challenged with phenylephrine...
February 15, 2018: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29445225/atrial-fibrillation-characteristics-in-patients-on-haemodialysis-vs-peritoneal-dialysis
#12
Ran Abuhasira, Yuval Mizrakli, Avi Shimony, Victor Novack, Alla Shnaider, Yosef S Haviv
Atrial fibrillation (AF) is highly prevalent in dialysis patients, however whether its impact differs between patients on haemodialysis (HD) vs. peritoneal dialysis (PD) is unknown. We aimed to compare the association of AF and clinical outcomes in different dialysis modalities. We performed a population based retrospective cohort study, including adult patients who initiated dialysis between the years 2002 and 2015. Clinical, echocardiographic and laboratory data were reviewed and correlated with outcomes in HD vs...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29444778/efficacy-and-safety-of-the-shexiang-baoxin-pill-for-the-treatment-of-coronary-artery-disease-not-amenable-to-revascularisation-study-protocol-for-a-randomised-placebo-controlled-double-blinded-trial
#13
Pan-Pan Tian, Jun Li, Jian Gao, Ying Li
INTRODUCTION: Coronary artery disease (CAD) not amenable to revascularisation indicates that the coronary arteries have severe diffuse lesions or calcifications, or that CAD is complicated with severe multiple-organ disease. Currently, Western medicines available for the treatment of CAD not amenable to revascularisation are limited. Shexiang Baoxin Pill (SBP), a type of Chinese patent medicine, has been widely used to treat CAD in China for many years. Previous studies have shown that long-term administration of SBP (1-2 pills three times daily, for at least 6 months) for treatment of CAD is effective and safe, with a significant, long-term effect...
February 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29444774/comparison-between-different-strategies-of-rheumatic-heart-disease-echocardiographic-screening-in-brazil-data-from-the-provar-rheumatic-valve-disease-screening-program-study
#14
Bruno R Nascimento, Craig Sable, Maria Carmo P Nunes, Adriana C Diamantino, Kaciane K B Oliveira, Cassio M Oliveira, Zilda Maria A Meira, Sandra Regina T Castilho, Júlia P A Santos, Letícia Maria M Rabelo, Karlla C A Lauriano, Gabriel A L Carmo, Allison Tompsett, Antonio Luiz P Ribeiro, Andrea Z Beaton
BACKGROUND: Considering the limited accuracy of clinical examination for early diagnosis of rheumatic heart disease (RHD), echocardiography has emerged as an important epidemiological tool. The ideal setting for screening is yet to be defined. We aimed to evaluate the prevalence and pattern of latent RHD in schoolchildren (aged 5-18 years) and to compare effectiveness of screening between public schools, private schools, and primary care centers in Minas Gerais, Brazil. METHODS AND RESULTS: The PROVAR (Rheumatic Valve Disease Screening Program) study uses nonexperts and portable and handheld devices for RHD echocardiographic screening, with remote interpretation by telemedicine, according to the 2012 World Heart Federation criteria...
February 14, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29444321/left-ventricular-regional-dyssynchrony-predicts-improvements-in-moderate-ischaemic-mitral-regurgitation-after-off-pump-coronary-artery-bypass
#15
Xiaotian Sun, Guoqian Huang, Jiechun Huang, Meng Shi, Fangrui Wang, Liewen Pang, Yiqing Wang
OBJECTIVES: The aim of this study was to explore the predictors of the improvement in moderate ischaemic mitral regurgitation (IMR) after off-pump coronary artery bypass grafting (OPCAB) focusing on left ventricular (LV) dyssynchrony. METHODS: A prospective study was performed among 135 patients (age at surgery, mean ± SD: 67.0 ± 8.2 years, 33.3% women) with prior myocardial infarction and moderate IMR undergoing OPCAB from 2008 to 2015. Preoperative and follow-up clinical and echocardiographic parameters were analysed, focusing on LV global/regional dyssynchrony...
February 12, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29444229/bioprosthetic-mitral-valve-replacement-in-patients-aged-65%C3%A2-years-or-younger-long-term-outcomes-with-the-carpentier-edwards-perimount-pericardial-valve
#16
Thierry Bourguignon, Fabien Espitalier, Clémence Pantaleon, Emmanuelle Vermes, Jean Marc El-Arid, Claudia Loardi, Elias Karam, Pascal Candolfi, Fabrice Ivanes, Michel Aupart
OBJECTIVES: Mitral valve replacement using a bioprosthesis remains controversial in young patients because data on long-term outcomes are missing. This study evaluated the long-term results of the PERIMOUNT pericardial mitral bioprosthesis in patients aged 65 years or younger. METHODS: From 1984 to 2010, 148 Carpentier-Edwards PERIMOUNT mitral bioprostheses were implanted in 148 patients aged 65 years or younger. Baseline clinical, perioperative and follow-up data were recorded prospectively...
February 12, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29442461/central-aortic-pressure-arterial-stiffness-and-echocardiographic-parameters-of-children-with-overweight-obesity-and-arterial-hypertension
#17
Jerzy Wójtowicz, Aleksandra Łempicka, Włodzimierz Łuczyński, Wojciech Szczepański, Aleksandra Zomerfeld, Kornel Semeran, Artur Bossowski
BACKGROUND: A non-invasive estimation of central aortic pressure and echocardiographic parameters, and appropriate interpretation thereof make it possible to determine the status of the vascular wall and myocardium. These parameters are early markers of unfavorable remodeling of the cardiovascular system. OBJECTIVES: The aim of this study was to analyze the central aortic pressure and echocardiographic parameters of overweight/obese children (with or without concomitant arterial hypertension)...
December 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29440842/coronary-sinus-atrial-septal-defect-without-persistent-left-superior-vena-cava-three-dimensional-imaging-of-a-rare-defect
#18
Sean Del-Rossi Quadros, Sreeja Pavithran, Ravi Agrawal, Kothandam Sivakumar
Coronary sinus defects refer to interatrial communications that lie out of the confines of the atrial septum and leads from left to right shunt through the ostium of the coronary sinus. When associated with persistent left superior vena cava (PLSVC), mild systemic desaturation may occur depending on the extent of unroofing of the coronary sinus. Isolated defects without PLSVC are rare. Three-dimensional echocardiographic and surgical images are presented.
January 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/29440827/evaluation-of-left-ventricular-function-in-obese-children-without-hypertension-by-a-tissue-doppler-imaging-study
#19
Yazdan Ghandi, Mehrzad Sharifi, Danial Habibi, Fatemeh Dorreh, Mojtaba Hashemi
Background: The prevalence of obesity is increasing worldwide. Obese children without hypertension are becoming an important health challenge. Aims: Complications of obesity in adults are well established, but in obese children, cardiac dysfunction has not been reported clinically. Settings and Design: The present crosssectional study investigates subclinical systolic and diastolic dysfunction using echocardiographic modalities. Materials and Methods: Twentyfive youngsters with body mass index (BMI) >30 and 25 healthy children with BMI <25 were assigned into case and control group, respectively...
January 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/29440154/outcomes-comparison-of-different-surgical-strategies-for-the-management-of-severe-aortic-valve-stenosis-study-protocol-of-a-prospective-multicentre-european-registry-e-avr-registry
#20
Francesco Onorati, Riccardo Gherli, Giovanni Mariscalco, Evaldas Girdauskas, Eduardo Quintana, Francesco Santini, Marisa De Feo, Sandro Sponga, Piergiorgio Tozzi, Mohamad Bashir, Andrea Perrotti, Aniello Pappalardo, Vito Ruggieri, Giuseppe Santarpino, Mauro Rinaldi, Silva Ronaldo, Francesco Nicolini
INTRODUCTION: Traditional and transcatheter surgical treatments of severe aortic valve stenosis (SAVS) are increasing in parallel with the improved life expectancy. Recent randomised controlled trials (RCTs) reported comparable or non-inferior mortality with transcatheter treatments compared with traditional surgery. However, RCTs have the limitation of being a mirror of the predefined inclusion/exclusion criteria, without reflecting the 'real clinical world'. Technological improvements have recently allowed the development of minimally invasive surgical accesses and the use of sutureless valves, but their impact on the clinical scenario is difficult to assess because of the monocentric design of published studies and limited sample size...
February 10, 2018: BMJ Open
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