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https://www.readbyqxmd.com/read/27909213/hammertoe-correction-with-k-wire-fixation-compared-with-percutaneous-correction
#1
Mustafa Yassin, Avraham Garti, Eyal Heller, Dror Robinson
BACKGROUND: Kirschner wire (K-wire) fixation for correction of hammertoe deformity is the gold standard for hammertoe surgery fixation, the current study compares it to percutaneous surgery with 3M Coban dressings. METHODS: All hammertoe corrections performed were retrospectively reviewed. For the K-wire fixation group: resection arthroplasty of the proximal interphalangeal joint was performed and fixed with a K-wire. The percutaneous technique used involved percutaneous diaphyseal osteotomy of the middle and proximal phalanges combined with tendon release...
November 30, 2016: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/27908244/free-initiation-factors-eif4a-and-eif4b-are-dispensable-for-translation-initiation-on-uncapped-mrnas
#2
P A Sakharov, S Ch Agalarov
The formation of ribosomal 48S initiation complexes at the start AUG codon of uncapped mRNA leader sequences was studied using the methodology of primer extension inhibition (toe-printing). The experiments were performed in the system composed of purified individual components required for translation initiation. The formation of ribosomal 48S initiation complexes at the initiation codon was tested depending on the presence of the initiation factors eIF4F, eIF4A, and eIF4B. Several mRNAs containing short leader sequences lacking the extended secondary structure were studied...
October 2016: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/27906996/reach-the-person-behind-the-dementia-physical-therapists-reflections-and-strategies-when-composing-physical-training
#3
Anncristine Fjellman-Wiklund, Ellinor Nordin, Dawn A Skelton, Lillemor Lundin-Olsson
Dementia is a disease characterized by cognitive impairment and physical decline that worsens over time. Exercise is one lifestyle factor that has been identified as a potential means of reducing or delaying progression of the symptoms of dementia, maximizing function and independence. The purpose of this study was to explore physical therapists' (PTs) experiences and reflections on facilitating high-intensity functional exercise with older people living with dementia, in residential care home settings. The study used a qualitative design based on interviews, individually or in small groups, with seven PTs engaged as leaders in the training of older people with dementia...
2016: PloS One
https://www.readbyqxmd.com/read/27906045/smoking-is-associated-with-the-concurrent-presence-of-multiple-autoantibodies-in-rheumatoid-arthritis-rather-than-with-anti-citrullinated-protein-antibodies-per-se-a-multicenter-cohort-study
#4
Tineke J van Wesemael, Sofia Ajeganova, Jennifer Humphreys, Chikashi Terao, Ammar Muhammad, Deborah P M Symmons, Alex J MacGregor, Ingiäld Hafström, Leendert A Trouw, Annette H M van der Helm-van Mil, Tom W J Huizinga, Tsuneyo Mimori, René E M Toes, Fumihiko Matsuda, Björn Svensson, Suzanne M M Verstappen, Diane van der Woude
BACKGROUND: The contribution of smoking to rheumatoid arthritis (RA) is hypothesized to be mediated through formation of anti-citrullinated protein antibodies (ACPA). In RA, however, autoantibodies such as ACPA, rheumatoid factor (RF), and anti-carbamylated protein antibodies (anti-CarP) often occur together, and it is thus unclear whether smoking is specifically associated with some autoantibodies rather than others. We therefore investigated whether smoking is only associated with ACPA or with the presence of multiple RA-related autoantibodies...
December 1, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27904728/reconstruction-of-postburn-contracture-of-the-forefoot-using-the-anterolateral-thigh-flap
#5
Sang Hyun Lee, Sung Jin An, Nu Ri Kim, Um Ji Kim, Jeung Il Kim
BACKGROUND: Severe forefoot deformities, particularly those involving the dorsum of the foot, cause inconvenience in daily activities of living including moderate pain on the dorsal aspect of the contracted foot while walking and difficulty in wearing nonsupportive shoes due to toe contractures. This paper presents clinical results of reconstruction of severe forefoot deformity using the anterolateral thigh (ALT) free flap. METHODS: Severe forefoot deformities were reconstructed using ALT flaps in 7 patients (8 cases) between March 2012 and December 2015...
December 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27904023/early-embryonic-development-of-long-tendons-in-the-human-foot
#6
Masahito Yamamoto, Yasuhiro Shiraishi, Kei Kitamura, Zhe Wu Jin, Gen Murakami, Jose Francisco Rodríguez-Vázquez, Shin-Ichi Abe
To examine a common plantar tendinous plate for long flexors of the toe and fingers in human embryos, we observed sections of 10 embryos at 5-6 weeks (crown-rump length or CRL 15-21 mm). The heel or tuber of the calcaneus was underdeveloped in 3 embryos with CRL 15 mm and the talus appeared not to be piled up on the calcaneus but these two bones were arranged along the lateromedial axis. As reported in the hand, we demonstrated, in the deep side of tarsal bones, a common tendinous plate formed by a joining of the flexor halluces longus and flexor digitorum longus tendons...
2016: Okajimas Folia Anatomica Japonica
https://www.readbyqxmd.com/read/27903927/crescentic-osteotomy-for-revision-hallux-interphalangeal-joint-arthrodesis
#7
Andrew Franklin, Patrick McKee, Joris Claessens
: Treatment for rigid mallet toe deformity of the hallux has commonly consisted of arthrodesis of this interphalangeal joint. However, such procedure is not without complications resulting in operative revision. We report on a case of considerable deformity of the distal phalanx of the hallux following hallux interphalangeal joint arthrodesis that underwent revision using a unique crescentic osteotomy technique. LEVELS OF EVIDENCE: Level V: Case report/Technique...
November 30, 2016: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/27903628/the-role-of-plantigrady-and-heel-strike-in-the-mechanics-and-energetics-of-human-walking-with-implications-for-the-evolution-of-the-human-foot
#8
James T Webber, David A Raichlen
Human bipedal locomotion is characterized by a habitual heel-strike (HS) plantigrade gait, yet the significance of walking foot-posture is not well understood. To date, researchers have not fully investigated the costs of non-heel-strike (NHS) walking. Therefore, we examined walking speed, walk-to-run transition speed, estimated locomotor costs (lower limb muscle volume activated during walking), impact transient (rapid increase in ground force at touchdown) and effective limb length (ELL) in subjects (n=14) who walked at self-selected speeds using HS and NHS gaits...
December 1, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27902701/heads-shoulders-elbows-knees-and-toes-modular-gdf5-enhancers-control-different-joints-in-the-vertebrate-skeleton
#9
Hao Chen, Terence D Capellini, Michael Schoor, Doug P Mortlock, A Hari Reddi, David M Kingsley
Synovial joints are crucial for support and locomotion in vertebrates, and are the frequent site of serious skeletal defects and degenerative diseases in humans. Growth and differentiation factor 5 (Gdf5) is one of the earliest markers of joint formation, is required for normal joint development in both mice and humans, and has been genetically linked to risk of common osteoarthritis in Eurasian populations. Here, we systematically survey the mouse Gdf5 gene for regulatory elements controlling expression in synovial joints...
November 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27900398/-dyspnea-and-skin-rash-in-a-49-year-old-male-patient
#10
I El-Battrawy, U Ansari, M Behnes, W Kirschstein, S Britsch, C Jabbour, C Fastner, V Bill, M Borggrefe, I Akin
We report on the case of a 49-year-old man who presented with increasing dyspnea and a skin rash. The community-acquired pneumonia was initially treated with broad spectrum antibiotics. The patient's respiratory condition rapidly worsened and the clinical picture of Waterhouse-Friderichsen syndrome developed with disseminated intravasal coagulopathy and necrosis of the toes. An infection with Capnocytophaga canimorsus, which had been caused by an initially unmentioned dog bite was confirmed. In view of the fulminant course and the high risk of operative treatment of the ubiquitous necroses in all limbs, a joint decision for deescalation of therapy was made together with relatives...
November 29, 2016: Der Internist
https://www.readbyqxmd.com/read/27900336/optimal-lateral-row-anchor-positioning-in-posterior-superior-transosseous-equivalent-rotator-cuff-repair-a-micro-computed-tomography-study
#11
Matthias A Zumstein, Sumit Raniga, Agatha Labrinidis, Kevin Eng, Gregory I Bain, Beat K Moor
BACKGROUND: The optimal placement of suture anchors in transosseous-equivalent (TOE) double-row rotator cuff repair remains controversial. PURPOSE: A 3-dimensional (3D) high-resolution micro-computed tomography (micro-CT) histomorphometric analysis of cadaveric proximal humeral greater tuberosities (GTs) was performed to guide optimal positioning of lateral row anchors in posterior-superior (infraspinatus and supraspinatus) TOE rotator cuff repair. STUDY DESIGN: Descriptive laboratory study...
November 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/27898961/effects-of-feeding-regimen-on-weight-gain-semen-characteristics-libido-and-lameness-in-170-to-250-kilogram-duroc-boars
#12
C Wang, J L Li, H K Wei, Y F Zhou, J J Tan, H Q Sun, S W Jiang, J Peng
A 2-period field trial was conducted to determine the effects of feeding regimen on weight gain, semen characteristics, libido, and lameness in 170- to 200-kg (period 1) and 200- to 250-kg (period 2) boars. Sixty-one Duroc boars were allotted to 1 of 3 dietary treatments and 15 g/d fish oil was also provided for each experimental boar, to maintain the n-6:n-3 intake ratio at approximately 6.1:1. The energy intakes of the 3 treatment groups were controlled by basing the feed intake on a corn-soybean meal-based diet (3...
November 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27896688/design-simulation-and-modelling-of-auxiliary-exoskeleton-to-improve-human-gait-cycle
#13
O Ashkani, A Maleki, N Jamshidi
Exoskeleton is a walking assistance device that improves human gait cycle through providing auxiliary force and transferring physical load to the stronger muscles. This device takes the natural state of organ and follows its natural movement. Exoskeleton functions as an auxiliary device to help those with disabilities in hip and knee such as devotees, elderly farmers and agricultural machinery operators who suffer from knee complications. In this research, an exoskeleton designed with two screw jacks at knee and hip joints...
November 28, 2016: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/27895669/myeloproliferative-disease-an-unusual-cause-of-raynaud-s-phenomenon-and-digital-ischaemia
#14
Celia Beynon, Gwenan Huws, Tom Lawson
We describe a 59-year-old female who presented with ischaemic digits, preceded by a 6-month history of Raynaud's phenomenon affecting her fingers and toes. There were no clinical or laboratory features of primary vasculitis or connective tissue disease, Doppler imaging was normal, and bloods were unremarkable aside from a platelet count of 786 × 109/L (150-400) and white cells of 16 × 109/L (4-11). In view of the thrombocytosis a JAK2 mutation assay was requested which confirmed a JAK2 V617F mutation, suggesting essential thrombocytosis (ET) as the cause...
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27894834/a-podoscopic-and-descriptive-study-of-foot-deformities-in-patients-with-down-syndrome
#15
E Mansour, J J Yaacoub, Z Bakouny, A Assi, I Ghanem
INTRODUCTION: Subjects with Down syndrome (DS) are known to be affected by various foot deformities. Despite the fact that some of these deformities have been reported in the literature, a more comprehensive description would be of benefit. The aim of this study is to investigate the prevalence of known foot deformities in patients with DS and of other previously non-described foot anomalies in this population. HYPOTHESIS: Subjects with DS have an increased prevalence of foot deformities compared to control subjects...
November 25, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27893476/comparison-of-muscle-involvement-and-posture-between-the-conventional-deadlift-and-a-walk-in-style-deadlift-machine
#16
Benjamin J Snyder, Courtney P Cauthen, Scott R Senger
The deadlift exercise is one of the most effective exercises for developing lower-body strength; however, technique errors can lead to low back injuries. The use of a 'walk-in' deadlift machine removes the weight bar by using a lever system with independent handles on either side of the body. Theoretically, this would allow alignment of the load with the center of gravity, encouraging a more upright torso and decreasing the involvement of the low back extensors. This study compared trunk angle, knee angle and electrical activity of key muscles between the conventional deadlift (CDL) and two foot positions (ball of foot or toe alignment) with pronated grip, (called BallPro and ToePro) of a walk-in deadlift machine among high-skilled and low-skilled lifters...
November 16, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27890769/real-time-monitoring-of-results-during-first-year-of-dutch-colorectal-cancer-screening-program-and-optimization-by-altering-fecal-immunochemical-test-cut-off-levels
#17
Esther Toes-Zoutendijk, Monique E van Leerdam, Evelien Dekker, Frank van Hees, Corine Penning, Iris Nagtegaal, Miriam P van der Meulen, Anneke J van Vuuren, Ernst J Kuipers, Johannes M G Bonfrer, Katharina Biermann, Maarten G J Thomeer, Harriët van Veldhuizen, Sonja Kroep, Marjolein van Ballegooijen, Gerrit A Meijer, Harry J de Koning, Manon C W Spaander, Iris Lansdorp-Vogelaar
BACKGROUND AND AIM: After careful pilot studies and planning, the national screening program for colorectal cancer (CRC), with biennial fecal immunochemical tests (FITs), was initiated in the Netherlands in 2014. A national information system for real-time monitoring was developed to allow for timely evaluation. Data was collected from the first year of this screening program to determine the importance of planning and monitoring for optimal screening program performance. METHODS: The national information system of the CRC screening program kept track on the number of invitations sent in 2014, FIT kits returned, and colonoscopies performed...
November 24, 2016: Gastroenterology
https://www.readbyqxmd.com/read/27890129/toe-spatiotemporal-differences-between-transition-steps-when-ascending-shorter-flight-stairways-of-different-heights
#18
Toyin Ajisafe, Jianhua Wu, Mark Geil
BACKGROUND: Studies have typically treated the first and second floor-to-stair transition steps (TS1 and TS2) as one stride. However, because the foot is devoid of plantar cutaneous input from the stair surface at TS1, these steps may have different toe spatiotemporal profiles, and resultantly, different susceptibilities to a trip and/or a fall. This study compared vertical toe clearance, forward velocity, and their respective variability magnitudes between TS1 and TS2 when ascending stairs of different heights...
March 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/27889978/-analysis-of-plantar-pressure-patterns-among-obese-population
#19
Eleonóra Leidecker, Péter Kellermann, Mónika Galambosné Tiszberger, Bálint Molics, Aliz Bohner-Beke, József Nyárády, János Kránicz
INTRODUCTION: Although the role of body weight on foot health and load has been widely documented in research, the effect of the extra load due to body weight on plantar pressure characteristics is not well known. AIM: The aim of this study was to evaluate the impact of obesity on plantar pressure patterns among the working-age population. METHOD: 180 participants were involved. Two groups were evaluated according to body mass index categories regarding eight regions of the plantar area, focusing on the following parameters: contact area, maximum pressure and peak pressure...
November 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/27888844/mr-imaging-of-the-plantar-plate-normal-anatomy-turf-toe-and-other-injuries
#20
REVIEW
Caio Nery, Daniel Baumfeld, Hilary Umans, André F Yamada
The metatarsophalangeal (MTP) joint complex is a weight-bearing structure important to the biomechanics of the standing position, walking, shoe wearing, and sport participation. Acute dorsiflexion injury of the first MTP joint, "turf toe," is common among American football and soccer players. The first and lesser MTP joint complexes can be affected by degenerative or inflammatory arthritis, infarct, and infection. These conditions can lead to plantar plate disruption. Imaging studies help physicians to properly diagnose and treat this condition...
February 2017: Magnetic Resonance Imaging Clinics of North America
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