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https://www.readbyqxmd.com/read/28441640/lack-of-association-between-limb-hemodynamics-and-response-to-infrapopliteal-endovascular-therapy-in-patients-with-critical-limb-ischemia
#1
J A Mustapha, Larry J Diaz-Sandoval, George Adams, Michael R Jaff, Robert Beasley, Theresa McGoff, Sara Finton, Larry E Miller, Mohammad Ansari, Fadi Saab
BACKGROUND: Non-invasive limb hemodynamics may aid in diagnosis of critical limb ischemia (CLI), although the relationship with disease severity and response to endovascular therapy is unclear. METHODS AND RESULTS: This prospective, single-center study enrolled 100 CLI patients (Rutherford class 4-6) who underwent infrapopliteal endovascular revascularization (175 lesions) in the Peripheral RegIstry of Endovascular Clinical OutcoMEs (PRIME) registry. Hemodynamic measures included ankle-brachial index (ABI), toe-brachial index (TBI), and toe pressure (TP)...
May 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28437922/from-toes-to-top-of-atmosphere-fowler-s-sneaker-depth-index-of-water-clarity-for-the-chesapeake-bay
#2
Benjamin Crooke, Lachlan I W McKinna, Ivona Cetinić
Fowler's Sneaker Depth (FSD), analogous to the well known Secchi disk depth (Zsd), is a visually discerned citizen scientist metric used to assess water clarity in the Patuxent River estuary. In this study, a simple remote sensing algorithm was developed to derive FSD from space-borne spectroradiometric imagery. An empirical model was formed that estimates FSD from red-end remote sensing reflectances at 645 nm, Rrs(645). The model is based on a hyperbolic function relating water clarity to Rrs(645) that was established using radiative transfer modeling and fine tuned using in-water FSD measurements and coincident Rrs(645) data observed by NASA's Moderate Resolution Imaging Spectroradiometer aboard the Aqua spacecraft (MODISA)...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437760/the-effects-of-object-height-and-visual-information-on-the-control-of-obstacle-crossing-during-locomotion-in-healthy-older-adults
#3
Sho Kunimune, Shuichi Okada
In order to safely avoid obstacles, humans must rely on visual information regarding the position and shape of the object obtained in advance. The present study aimed to reveal the duration of obstacle visibility necessary for appropriate visuomotor control during obstacle avoidance in healthy older adults. Participants included 13 healthy young women (mean age: 21.5±1.4years) and 15 healthy older women (mean age: 68.5±3.5years) who were instructed to cross over an obstacle along a pressure-sensitive pathway at a self-selected pace while wearing liquid crystal shutter goggles...
April 13, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28437499/systemic-hypothermia-as-treatment-for-an-acute-cervical-spinal-cord-injury-in-a-professional-football-player-9-year-follow-up
#4
Andrew Cappuccino, Leslie J Bisson, Bud Carpenter, Ken Snyder, Helen Cappuccino
The following report provides clinical follow-up on a National Football League player who sustained a complete cervical spinal cord injury (SCI) while tackling an opposing player in 2007. He received prompt medical and surgical care based on then-current recommendations, but was also treated with systemic hypothermia soon after his injury, which was controversial at the time. Since then, smaller randomized human studies have described the tolerable safety profile, efficacy, and potential benefits of this intervention in acute SCI in humans...
March 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28437244/second-transcatheter-closure-for-residual-shunt-following-percutaneous-closure-of-patent-foramen-ovale
#5
Njomeza Susuri, Slayman Obeid, Mirjam Ulmi, George Cm Siontis, Andreas Wahl, Stephan Windecker, Fabian Nietlispach, Bernhard Meier, Fabien Praz
AIMS: Residual shunt following percutaneous patent foramen ovale (PFO) closure has been described in up to 49% of the patients and is associated with recurrent cerebrovascular events. Our aim was to evaluate the safety, feasibility, and mid-term outcomes of transcatheter residual shunt closure. METHODS AND RESULTS: From 1994 to July 2016, 2679 patients underwent transcatheter PFO closure for treatment of presumed paradoxical embolism at our institution. Among them, 100 patients (3...
April 25, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28437082/high-efficiency-1-and-2-ribosomal-frameshiftings-revealed-by-force-spectroscopy
#6
Te-Wei Tsai, Haopeng Yang, Heng Yin, Shoujun Xu, Yuhong Wang
Ribosomal frameshifting is a rare but ubiquitous process that is being studied extensively. Meanwhile, frameshifting motifs without any secondary mRNA structures were identified but rarely studied experimentally. We report unambiguous observation of highly efficient "-1" and "-2" frameshiftings on a GA7G slippery mRNA without the downstream secondary structure, using force-induced remnant magnetization spectroscopy combined with unique probing schemes. The result represents the first experimental evidence of multiple frameshifting steps...
April 24, 2017: ACS Chemical Biology
https://www.readbyqxmd.com/read/28436371/pigmented-villonodular-synovitis-various-manifestations-inconsistent-terminology-and-treatment-cases-study
#7
Paweł Kokoszka, Waldemar Woźniak, Łukasz Łapaj, Jacek Kruczyński
Pigmented villonodular synovitis (PVNS) as well as tenosynovial giant cell tumor (TGCT) are both diagnosed and described in two forms, namely a localized and diffuse type. They form a diverse group of proliferative lesions in articular synovium and tendon sheaths. The inconsistent terminology impedes communication between patients, orthopedic surgeons, radiologists and pathologists, leading to misunderstandings and delaying treatment. In this paper, we present three cases of PVNS/TGCT (involving the fourth toe extensor tendon sheath, hip joint after resurfacing and flexor hallucis longus tendon sheath) together with suggestions regarding the unification of the terminology as well as diagnosis and treatment...
January 26, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28435580/first-and-second-metatarsophalangeal-joint-open-dislocations-a-case-report
#8
A Sharma, R Dosajh, G S Bedi, K Gupta, A Jain
Dislocation of multiple metatarsophalangeal joint is an uncommon injury. The mechanism of injury is a high energy force distal to proximal with foot in hyperextension at the metatarsophalangeal (MTP) joint. The acute hyperextension of the toe at the moment of injury causes avulsion of the plantar part of the capsule from the junction of head and neck of the metatarsal. If the collateral ligaments remain intact, they maintain the locked fibrocartilaginous plate over the dorsum of the head of the metatarsal, making closed reduction impossible...
March 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28435579/peripheral-gangrene-complicating-systemic-lupus-erythematosus-in-a-patient-with-spina-bifida-a-case-report
#9
S Vijay, V K Imthiaz, S Hitesh
An adolescent girl, a known case of spina bifida with systemic lupus, presented with bluish discolouration of three toes of the right foot. She had thrombosis of bilateral popliteal arteries. She underwent percutaneous transluminal angioplasty (PTA) of both legs and Chopart amputation of the right foot. Systemic lupus erythematosus (SLE) occurring in a patient with spina bifida has not been previously reported. Weakness, sensory loss, lack of normal ambulation, endarteritis, antiphospholipid antibody syndrome are common contributory factors for peripheral gangrene in patients with spina bifida with systemic lupus erythematosus...
March 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28435080/investigating-mechanisms-of-tendon-damage-by-measuring-multi-scale-recovery-following-tensile-loading
#10
Andrea H Lee, Spencer E Szczesny, Michael H Santare, Dawn M Elliott
Tendon pathology is associated with damage. While tendon damage is likely initiated by mechanical loading, little is known about the specific etiology. Damage is defined as an irreversible change in the microstructure that alters the macroscopic mechanical parameters. In tendon, the link between mechanical loading and microstructural damage, resulting in macroscopic changes, is not fully elucidated. In addition, tendon damage at the macroscale has been proposed to initiate when tendon is loaded beyond a strain threshold, yet the metrics to define the damage threshold are not determined...
April 20, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28434640/imaging-guidance-for-transcatheter-aortic-valve-replacement-is-transoesophageal-echocardiography-the-gold-standard
#11
REVIEW
Bo Xu, Philip M Mottram, Siobhan Lockwood, Ian T Meredith
Transcatheter aortic valve replacement (TAVR) is traditionally performed under cardiac imaging guidance. In the early TAVR experience, intra-procedural transoesophageal echocardiography (TOE) is recommended to guide device deployment, in the context of general anaesthesia (GA). Intra-procedural TOE imaging is particularly useful during TAVR deployment as a contrast-saving strategy for patients with renal impairment. Evidence has emerged recently demonstrating that in selected patients, transthoracic echocardiography (TTE) can be used to provide intra-procedural guidance for TAVR...
March 27, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28431451/-experience-with-the-hind-foot-relaxation-boot
#12
Hans Zwipp, Michael Borrmann, Eberhard Walter
The goal of this paper is to report our experience with hindfoot fractures using our specially developed boot, with a follow-up of 557 cases. This boot works like the well-known Allgöwer-Röck ortheses (ARO), but is a hybrid between a boot and an orthesis. It allows full weightbearing without using crutches and completely protects an acutely operated hind foot fracture, hind foot arthrodesis or a hind foot fracture which is suitable for conservative treatment. In its first generation, this boot was custom made and used in 408 cases, from March 1999 to February 2011...
April 21, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28430703/evidence-based-recommendations-for-pediatric-orthopaedic-practice
#13
Kishore Mulpuri, Emily K Schaeffer, H Kerr Graham, Mininder S Kocher, James Sanders, Ira Zaltz
BACKGROUND: Evidence-based medicine has become the cornerstone to guide clinical practice decision-making. Evidence-based medicine integrates the strongest available evidence with clinical expertise to make decisions about clinical care. The quality of the evidence depends upon the soundness of the study methodology to allow for meaningful interpretation of the clinical results. The purpose of this review is to analyze the methodological design and clinical findings of published pediatric orthopaedic studies to determine their ability to change or influence clinical practice...
April 20, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28429644/a-systematic-review-of-discomfort-due-to-toe-or-ear-clipping-in-laboratory-rodents
#14
Kimberley E Wever, Florentine J Geessink, Michelle A E Brouwer, Alice Tillema, Merel Ritskes-Hoitinga
Toe clipping and ear clipping (also ear notching or ear punching) are frequently used methods for individual identification of laboratory rodents. These procedures potentially cause severe discomfort, which can reduce animal welfare and distort experimental results. However, no systematic summary of the evidence on this topic currently exists. We conducted a systematic review of the evidence for discomfort due to toe or ear clipping in rodents. The review methodology was pre-specified in a registered review protocol...
January 1, 2017: Laboratory Animals
https://www.readbyqxmd.com/read/28428657/x-ray-and-computed-tomography-findings-in-macrodystrophia-lipomatosa-of-the-foot-with-secondary-osteoarthritic-changes-diagnosed-in-an-elderly-female-a-case-report
#15
Rajesh Sharma, Puneet Gupta, Manik Mahajan, Manjit Arora, Anchal Gupta
Macrodystrophia lipomatosa is a rare entity that is mostly diagnosed in children. It has been very rarely reported in adults. Here, we describe the X-ray and computed tomography findings in a case of macrodystrophia lipomatosa in an elderly female presenting with an enlarged second toe since birth and bony outgrowths causing pressure effects and cosmetic problems.
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28426950/testing-the-validity-of-a-continuous-false-belief-task-in-3-to-7-year-old-children
#16
Caitlin E V Mahy, Daniel M Bernstein, Lindsey D Gerrard, Cristina M Atance
In two studies, we examined young children's performance on the paper-and-pencil version of the Sandbox task, a continuous measure of false belief, and its relations with other false belief and inhibition tasks. In Study 1, 96 children aged 3 to 7years completed three false belief tasks (Sandbox, Unexpected Contents, and Appearance/Reality) and two inhibition tasks (Head-Shoulders-Knees-Toes and Grass/Snow). Results revealed that false belief bias-a measure of egocentrism-on the Sandbox task correlated with age but not with the Unexpected Contents or Appearance/Reality task or with measures of inhibition after controlling for age...
April 17, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28423999/toe-brachial-index-measured-by-automated-device-compared-to-duplex-ultrasonography-for-detecting-peripheral-arterial-disease-in-older-people
#17
Jennifer Sonter, Peta Tehan, Vivienne Chuter
Introduction To investigate the diagnostic accuracy of an automated toe blood pressure device for detecting peripheral arterial disease in older people. Methods Ninety participants underwent toe and brachial blood pressure measurements and colour duplex ultrasonography of the right lower limb. Peripheral arterial disease was diagnosed if > 50% arterial obstruction was identified in any lower limb vessel using colour duplex ultrasonography. A receiver operating characteristic curve was analysed and the sensitivity and specificity of commonly used toe brachial index and toe blood pressure values were determined...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28422563/effects-of-anterior-knee-displacement-during-squatting-on-patellofemoral-joint-stress
#18
Thomas W Kernozek, Naghmeh Gheidi, Matthew Zellmer, Jordan Hove, Becky L Heinert, Michael R Torry
CONTEXT: Squatting is a common rehabilitation training exercise for Patellofemoral pain syndrome (PFPS). Patellofemoral joint stress (PFJS) during squatting with more anterior knee displacement has not been systematically investigated. OBJECTIVE: The aim was to compare PFJS during squatting using two techniques: Squat while keeping the knees before the toes (SBT) and squat while allowing the knees to go past the toes (SPT). SETTING: University research laboratory...
April 19, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28421275/no-association-between-hand-and-foot-temperature-responses-during-local-cold-stress-and-rewarming
#19
Lena Norrbrand, Roger Kölegård, Michail E Keramidas, Igor B Mekjavic, Ola Eiken
PURPOSE: The purpose was to examine whether associations exist between temperature responses in the fingers vs. toes and hand vs. foot during local cold-water immersion and rewarming phases. METHODS: Seventy healthy subjects (58 males, 12 females) immersed their right hand or right foot, respectively, in 8 °C water for 30 min (CWI phase), followed by a 15-min spontaneous rewarming (RW) in 25 °C air temperature. RESULTS: Temperature was lower in the toes than the fingers during the baseline phase (27...
April 18, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28420896/toe-pinch-force-in-male-type-2-diabetes-mellitus-patients
#20
Hiroaki Kataoka, Nobuyuki Miyatake, Naomi Kitayama, Satoshi Murao, Satoshi Tanaka
We compared the toe pinch force in men with and without type 2 diabetes mellitus (T2DM). Sixty-eight male T2DM patients and 35 apparently healthy men matched for age, sex, and body mass index (BMI) were enrolled in this cross-sectional study. We compared the toe pinch force between the subjects with and without T2DM, and we evaluated the effect of diabetic polyneuropathy on toe pinch force in the patients. The toe pinch force of the T2DM patients was significantly lower than that of the subjects without diabetes (3...
April 2017: Acta Medica Okayama
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