keyword
MENU ▼
Read by QxMD icon Read
search

Muscular rupture

keyword
https://www.readbyqxmd.com/read/29771357/a-promotive-effect-for-halofuginone-on-membrane-repair-and-synaptotagmin-7-levels-in-muscle-cells-of-dysferlin-null-mice
#1
Hila Barzilai-Tutsch, Melissa Dewulf, Christophe Lamaze, Gillian Butler Browne, Mark Pines, Orna Halevy
In the absence of dysferlin, skeletal muscle cells fail to reseal properly after injury, resulting in slow progress of the dysferlinopathy muscular dystrophy. Halofuginone, a leading agent in preventing fibrosis in muscular dystrophies, was tested for its effects on membrane resealing post-injury. A hypo-osmotic shock assay on myotubes derived from wild-type and dysferlin-null (dysf-/-) mice revealed that pre-treatment with halofuginone reduces the percentage of membrane-ruptured myotubes only in dysf-/- myotubes...
May 16, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29712757/defective-flux-of-thrombospondin-4-through-the-secretory-pathway-impairs-cardiomyocyte-membrane-stability-and-causes-cardiomyopathy
#2
Matthew J Brody, Davy Vanhoutte, Tobias G Schips, Justin G Boyer, Chinmay V Bakshi, Michelle A Sargent, Allen J York, Jeffery D Molkentin
Thrombospondins are stress-inducible secreted glycoproteins with critical functions in tissue injury and healing. Thrombospondin-4 (Thbs4) is protective in cardiac and skeletal muscle where it activates an adaptive endoplasmic reticulum (ER) stress-response, induces expansion of the ER, and enhances sarcolemmal stability. However, it is unclear if Thbs4 has these protective functions from within the cell, from the extracellular matrix, or from the secretion process itself. Here we generated transgenic mice with cardiac-specific overexpression of a secretion-defective mutant of Thbs4 to evaluate its exclusive intracellular and secretion-dependent functions...
April 30, 2018: Molecular and Cellular Biology
https://www.readbyqxmd.com/read/29650820/-rectal-mucinous-cancer-with-submucosal-tumor-like-morphology-preoperatively-diagnosed-using-eus-fnab-a-case-report
#3
Tomoko Matsumoto, Shiho Kuriyama, Yasuyuki Ohtawa, Toshihiko Waku
A man in his 70s presented with a chiefcomplaint ofbleeding during bowel movements. Subsequent colonoscopy revealed a submucosal tumor-like elevated lesion ofapproximately 4 cm situated in the sigmoid section ofthe rectum. EUS-FNAB was performed, and the lesion was identified as mucinous cancer. Based on a diagnosis of rectal cancer(cT4a, cN0, cM0, cStage II), a low anterior resection was performed. Histopathological analysis of the resected specimen revealed a well-differentiated mucinous cancer. The tumor had ruptured the proper muscular layer and was developing in a submucosal tumor-like manner, protruding from the wall within a fibrous capsule...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29518517/spontaneous-deep-femoral-artery-false-aneurysm-simulating-a-neoplasm-a-rare-case-and-literature-review
#4
Raffaele Grande, Paolo Ossola, Ciro Ferrer, Luigi Venturini, Marco Bononi, Carlo Della Rocca, Luca di Marzo
A 70-year-old woman presented to our attention with a painless pulsating mass at the level of the upper left thigh without any previous history of trauma, arterial surgery, or puncture of the femoral artery. Duplex ultrasound showed a nodular angiomatous-like formation with deep venous compression; computed tomographic angiography and magnetic resonance imaging reported the presence of capsulated lesion vascularized by muscular branch of deep femoral artery (DFA). The patient underwent surgical excision of a very rare thrombized DFA branch false aneurysm...
March 5, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29477554/blood-flow-restriction-training-after-achilles-tendon-rupture
#5
Bobby G Yow, David J Tennent, Thomas C Dowd, Jeremy P Loenneke, Johnny G Owens
Blood flow restriction (BFR) training is a technique shown to be safe and effective at increasing muscular strength and endurance in healthy fitness populations and is under study for its use in postinjury rehabilitation. BFR stimulates muscular strength and hypertrophy gains at much lower loads than traditional methods, allowing patients to begin the rehabilitation process much sooner. We report on 2 patients who incorporated BFR training into their traditional rehabilitation program after Achilles tendon ruptures...
May 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29451037/esophageal-hiatal-hernia-risk-diagnosis-and-management
#6
Hai-Xiang Yu, Chun-Shan Han, Jin-Ru Xue, Zhi-Feng Han, Hua Xin
Esophageal hiatal hernia involves abnormal abdominal entry into thoracic cavity. It is classified based on orientation between esophageal junction and diaphragm. Sliding hiatal hernia (Type-I) comprises the most frequent category, emanating from right crus of diaphragm. Type-II esophageal hernia engages both left and right muscular crura. Type-III and IV additionally include the left crus. Age and increased body mass index are key risk factors, and congenital skeletal aberrations trigger pathogenesis through intestinal malrotations...
April 2018: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29412689/branched-fibers-from-old-fast-twitch-dystrophic-muscles-are-the-sites-of-terminal-damage-in-muscular-dystrophy
#7
Leonit Kiriaev, Sindy Kueh, John W Morley, Kathryn N North, Peter J Houweling, Stewart I Head
A striking pathological feature of dystrophinopathies is the presence of morphologically abnormal branched skeletal muscle fibers. The deterioration of muscle contractile function in Duchenne muscular dystrophy is accompanied by both an increase in number and complexity of these branched fibers. We propose that when number and complexity of branched fibers reaches a critical threshold, "tipping point" the branches in and of themselves are the site of contraction-induced rupture. In the present study, we use the dystrophic mdx mouse and littermate controls to study the pre-diseased dystrophic fast-twitch EDL muscle at 2-3-weeks, the peak myonecrotic phase at 6-9 weeks and finally "old" at 58-112 weeks...
February 7, 2018: American Journal of Physiology. Cell Physiology
https://www.readbyqxmd.com/read/29408692/proteomic-analysis-of-the-sarcolemma-enriched-fraction-from-dystrophic-mdx-4cv-skeletal-muscle
#8
Sandra Murphy, Margit Zweyer, Michael Henry, Paula Meleady, Rustam R Mundegar, Dieter Swandulla, Kay Ohlendieck
The highly progressive neuromuscular disorder dystrophinopathy is triggered by primary abnormalities in the Dmd gene, which causes cytoskeletal instability and loss of sarcolemmal integrity. Comparative organellar proteomics was employed to identify sarcolemma-associated proteins with an altered concentration in dystrophic muscle tissue from the mdx-4cv mouse model of dystrophinopathy. A lectin agglutination method was used to prepare a sarcolemma-enriched fraction and resulted in the identification of 190 significantly changed protein species...
February 2, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29234649/total-bilateral-ruptures-of-the-knee-extensor-apparatus
#9
Diogo Lino Moura, José Pedro Marques, João Páscoa Pinheiro, Fernando Fonseca
Objective: Bilateral extensor tendon ruptures of the knee are rare and have only been published in the form of case reports or small series. Methods: Seven patients corresponding to 14 extensor tendon ruptures of the knee were evaluated by the same examiner after a minimum one year post-surgery. Clinical and radiographic evaluations were performed; for statistical analysis, the level of significance was set at 0.05. Results: The most common injury was patellar tendon rupture ( n  = 9; 64...
November 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29131778/adventures-and-misadventures-in-plastic-surgery-and-soft-tissue-implants
#10
Dana J Lin, Tony T Wong, Gina A Ciavarra, Jonathan K Kazam
Soft-tissue augmentation and implants are increasingly seen by the radiologist as more techniques emerge for a variety of indications and locations. Some surgical and implant procedures are performed for purely cosmetic reasons in otherwise healthy patients seeking to improve their body image, and some are performed for reconstruction after cancer or other chronic illnesses. Abdominoplasty, liposuction, and autologous fat grafting can be performed for abdominal and gluteal contouring. Injection of liquid injectable silicone has historically been fraught with legal issues, although it continues to be used for augmentation in a variety of anatomic locations...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28969821/editorial-commentary-increased-risk-of-second-ruptures-and-poorer-outcomes-after-anterior-cruciate-ligament-injury-and-reconstruction-in-hypermobile-athletes-a-potential-synergism-of-passive-ligamentous-and-active-muscular-control-of-dynamic-knee-stability
#11
EDITORIAL
Timothy E Hewett
Graft failure rates were higher and inferior subjective outcomes were observed after anterior cruciate ligament reconstruction in patients with generalized hypermobility. This is a clear and corroborative finding that is highly consilient with other reports of similar studies from the published literature. However, controversy remains regarding other potentially predictive and confounding variables. For example, age, activity level, sex, and dynamic neuromuscular control were not considered in this interesting, important, and potentially impactful study...
October 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28963098/stent-assisted-coiling-of-a-ruptured-vertebrobasilar-junction-aneurysm-via-direct-vertebral-artery-puncture
#12
Tomas Dobrocky, Juergen Beck, Jan Gralla, Pasquale Mordasini
A 78-year-old patient was admitted with subarachnoid hemorrhage caused by rupture of a broad-based vertebrobasilar junction aneurysm. Direct endovascular access to the vertebrobasilar circulation was not possible due to chronic occlusion of the proximal dominant left vertebral artery (VA), hypoplastic right VA and posterior communicating arteries. The distal cervical left VA was reconstituted by muscular branches of the ascending cervical artery. Therefore, endovascular access was gained by direct percutaneous VA puncture guided by a roadmap-controlled anterior approach at the level of C5 proximally to the main reconstituting collateral feeders...
September 27, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28810551/alterations-in-biomechanical-properties-and-microstructure-of-colon-wall-in-early-stage-experimental-colitis
#13
Xiaohui Gong, Xiaojuan Xu, Sisi Lin, Yu Cheng, Jianhua Tong, Yongyu Li
The aim of the current study was to investigate the effects of early-stage dextran sodium sulfate (DSS)-induced mouse colitis on the biomechanical properties and microstructure of colon walls. In the present study, colitis was induced in 8-week-old mice by the oral administration of DSS, and then 10 control and 10 experimental colitis samples were harvested. Uniaxial tensile tests were performed to measure the ultimate tensile strength and ultimate stretches of colon tissues. In addition, histological investigations were performed to characterize changes in the microstructure of the colon wall following treatment...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28704210/factor-xiii-deficiency-in-south-of-tunisia
#14
Ines Maaloul, Moez Medhaffer, Nacim Louhichi, Imen Krichen, Sofien Alibi, Sana Kmiha, Hajer Aloulou, Faiza Fakhfakh, Moez Elloumi, Choumous Kallel, Mongia Hachicha
: Factor XIII deficiency is a rare autosomal recessive disorder of hemostasis characterized by a plasmatic factor XIII level less than 1% in homozygote and bleeding as of the youth. The aim of the study is to describe the clinical features and the outcome of the patients and to determine molecular characteristics. A retrospective study, was conducted on seven patients with factor XIII deficiency in the department of hematology and pediatrics, Hedi Chaker Hospital, Sfax, Tunisia during the period of 14 years (2001-2014)...
September 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28683329/abdominal-wall-hydatid-cyst-a-review-a-literature-with-a-case-report
#15
Abdulwahid M Salih, F H Kakamad, Zuhair D Hammood, Bzhwen Yasin, Dilshad M Ahmed
INTRODUCTION: Hydatid cyst (HC) disease is a serious health problem in endemic areas. It is a parasitic infection that commonly involves liver and lungs while muscular HC is rare. HC of abdominal wall was reported only six times. We reported a 39-year-old male presented with HC of the right loin who was managed surgically with brief literature review. CONCLUSION: HC should be put in the differential diagnosis of the abdominal wall masses. Its pre-operative diagnosis is important to prevent rupture with subsequent anaphylaxis and recurrence...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28597034/ultrasound-visualization-of-an-underestimated-structure-the-bicipital-aponeurosis
#16
M Konschake, H Stofferin, B Moriggl
PURPOSE: We established a detailed sonographic approach to the bicipital aponeurosis (BA), because different pathologies of this, sometimes underestimated, structure are associated with vascular, neural and muscular lesions; emphasizing its further implementation in routine clinical examinations. METHODS: The BA of 100 volunteers, in sitting position with the elbow lying on a suitable table, was investigated. Patients were aged between 18 and 28 with no history of distal biceps injury...
December 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28495576/quantitative-assessment-of-fatty-infiltration-and-muscle-volume-of-the-rotator-cuff-muscles-using-3-dimensional-2-point-dixon-magnetic-resonance-imaging
#17
Noboru Matsumura, Sota Oguro, Shigeo Okuda, Masahiro Jinzaki, Morio Matsumoto, Masaya Nakamura, Takeo Nagura
BACKGROUND: In patients with rotator cuff tears, muscle degeneration is known to be a predictor of irreparable tears and poor outcomes after surgical repair. Fatty infiltration and volume of the whole muscles constituting the rotator cuff were quantitatively assessed using 3-dimensional 2-point Dixon magnetic resonance imaging. METHODS: Ten shoulders with a partial-thickness tear, 10 shoulders with an isolated supraspinatus tear, and 10 shoulders with a massive tear involving supraspinatus and infraspinatus were compared with 10 control shoulders after matching age and sex...
May 8, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28465195/extensor-indicis-proprius-tendon-transfer-using-shear-wave-elastography
#18
J Lamouille, C Müller, S Aubry, S Bensamoun, W Raffoul, S Durand
The means for judging optimal tension during tendon transfers are approximate and not very quantifiable. The purpose of this study was to demonstrate the feasibility of quantitatively assessing muscular mechanical properties intraoperatively using ultrasound elastography (shear wave elastography [SWE]) during extensor indicis proprius (EIP) transfer. We report two cases of EIP transfer for post-traumatic rupture of the extensor pollicis longus muscle. Ultrasound acquisitions measured the elasticity modulus of the EIP muscle at different stages: rest, active extension, active extension against resistance, EIP section, distal passive traction of the tendon, after tendon transfer at rest and then during active extension...
March 7, 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28441166/minimally-invasive-organ-preserving-surgery-for-large-submucosal-tumors-in-the-abdominal-esophagus
#19
Eiji Kanehira, Takashi Tanida, Aya Kamei, Kodai Takahashi
BACKGROUND: Surgical resection of submucosal tumors (SMTs) in the abdominal esophagus is not standardized. Enucleation may be a minimally invasive option, whereas its oncological validity is not very clear. Moreover, how to treat the esophageal wall defect after enucleation and necessity of additional antireflux procedure are also undetermined. METHODS: In 13 patients with a SMT originating the abdominal esophagus laparoscopic enucleation was performed with preserving the integrity of submucosa...
June 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28359506/single-stage-hybrid-repair-of-right-aortic-arch-with-kommerell-s-diverticulum
#20
Cristian Rosu, Jean-François Dorval, Cherrie Zack Abraham, Raymond Cartier, Philippe Demers
Kommerell diverticulum is uncommon, and it carries risks of dissection or rupture. Hybrid aortic arch repair is being used increasingly for this pathology. We report the hybrid arch repair of Kommerell diverticulum in a 72-year-old woman known for muscular dystrophy and right aortic arch with aberrant left subclavian artery. Head-vessel debranching was performed through median sternotomy using a handmade, bifurcated, Dacron graft. Stent-grafting was performed from the ascending aorta to the proximal descending aorta...
April 2017: Annals of Thoracic Surgery
keyword
keyword
47097
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"