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Ishan Aditya, Zhen Jason Fan
No abstract text is available yet for this article.
June 2017: Canadian Medical Education Journal
Omar K Danner, Carl Lokko, Felicia Mobley, Montreka Dansby, Michael Maze, Brene' Bradley, Elizabeth Williams, Leslie Ray Matthews, Emma Harrington, Lisa Mack, Clarence Clark, Ken Wilson, Derrick Beech, Sheryl Heron, Ed Childs
BACKGROUND: According to the National Center for Educational Statistics, underrepresented minorities (URMs) are more likely to leave science, technology, engineering and mathematics (STEM) fields at higher rates than their peers during undergraduate studies. Many institutions of higher learning have implemented pipeline programs aimed at preparing and inspiring high school and college aged students in select careers in health sciences with varying levels of success. Research has shown that a health care workforce that mirrors the community they serve is more effective in reducing health disparities and increasing positive health outcomes...
April 2017: American Journal of Surgery
Angela Chang, Garrett Cavanaugh, Neil S Kumar, Margaret Lee, David Stein, Mary K Mulcahey
PURPOSE: Mini-Medical school programs have become an increasingly popular means of encouraging high-school students to consider medical professions. However, there is little research evaluating the long-term effect of these programs on influencing career choice. The purpose of our study was to determine the motivational factors for attending the Mini-Medical school programs at our institution, student satisfaction with their experience, and whether it impacts intended secondary education and career choices...
2016: Journal of the National Medical Association
Adam Tucker, Darren McCusker, Nidhi Gupta, Jonathon Bunn, Mark Murnaghan
INTRODUCTION: Arthroplasty is commonplace in orthopaedic practice, and post operative pain has been shown to substantially hinder recovery and discharge from hospital. OBJECTIVES: The current study assessed a multidisciplinary, multimodal Orthopaedic ERP in terms of its effect on patient perceived post operative pain in hip and knee arthroplasty. Secondary outcome was in the form of a cost analysis. METHODS: A prospective study was performed on consecutive arthroplasty patients across a 6 week period in a district orthopaedic unit...
May 2016: Ulster Medical Journal
Jordan S Querido, Joseph F Welch, Najib T Ayas, A William Sheel
INTRODUCTION: It has been demonstrated that the cerebrovascular response to hypoxia is blunted following 10 d of intermittent hypoxia (IH) in healthy humans. The purpose of this study was to test the hypothesis that IH reduces the cerebrovascular response to CO2. METHODS: Healthy male subjects (N=8; 25±2 yr) were exposed to 10 consecutive days of IH (12% O2 for 5 min followed by 5 min of normoxia for 1 h/d). The cerebrovascular response to CO2 was assessed prior to (PRE-IH) and following (POST-IH) the IH paradigm with transcranial Doppler ultrasound...
September 2015: Aerospace Medicine and Human Performance
Casey L Penn
No abstract text is available yet for this article.
August 2015: Journal of the Arkansas Medical Society
Patrícia Benites Gonçalves da Silva, Carolina Oliveira Rodini, Carolini Kaid, Adriana Miti Nakahata, Márcia Cristina Leite Pereira, Hamilton Matushita, Silvia Souza da Costa, Oswaldo Keith Okamoto
Medulloblastoma is a highly aggressive brain tumor and one of the leading causes of morbidity and mortality related to childhood cancer. These tumors display differential ability to metastasize and respond to treatment, which reflects their high degree of heterogeneity at the genetic and molecular levels. Such heterogeneity of medulloblastoma brings an additional challenge to the understanding of its physiopathology and impacts the development of new therapeutic strategies. This translational effort has been the focus of most pre-clinical studies which invariably employ experimental models using human tumor cell lines...
August 2016: Cytotechnology
Beatriz Salinas, Christopher P Irwin, Susanne Kossatz, Alexander Bolaender, Gabriela Chiosis, Nagavarakishore Pillarsetty, Wolfgang A Weber, Thomas Reiner
BACKGROUND: Although the understanding of the genetic and molecular basis of cancer has advanced significantly over the past several decades, imaging and treatment options for glioblastoma patients have been more limited (N Engl J Med 359:492-507, 2008). This is in part due to difficulties in diagnosing this disease early, combined with its diffuse, infiltrative growth. This study was aimed at the development of a novel diagnostic tool for glioblastoma through the synthesis of a small molecule based on radioiodinated poly(ADP-ribose)polymerase 1 (PARP1) targeted tracers...
December 2015: EJNMMI Research
Louisa Kulke, Janette Atkinson, Oliver Braddick
A peripheral target can either be fixated when the current central target disappears ('non-competition') or while the central target remains visible ('competition') in the Fixation Shift Paradigm, where saccadic latencies can be used as a measure of shifts of attention. Competition, which leads to much slower saccadic latencies in young infants, requires disengagement from the current target, a process which is believed to depend on descending cortical input to oculomotor systems and is diagnostic of cerebral developmental problems (review: Atkinson and Braddick, Dev Med Child Neurol, 2012)...
2015: Journal of Vision
Xin Feng, Sean Doherty, Ilya Yaroslavsky, Gregory Altshuler, Anna N Yaroslavsky
BACKGROUND AND OBJECTIVE: Laser non-ablative fractional treatment (NAFT) is an important part of armamentarium of modern dermatology. Recently, such treatments have become available in at-home setting due to advent of self-application NAFT devices. Safety and clinical efficacy of NAFT are well established in multiple studies. Less information is available on morphological and functional changes in tissue occurring as a result of NAFT. Polarization-enhanced multispectral wide-field imaging device allows for in vivo real time visualization of dermal structures...
February 2016: Lasers in Surgery and Medicine
Jenifer A Chatfield, Reneé Dewell, Astrid J Miranda, Stefania Wilcox, Ty J Vannieuwenhoven
OBJECTIVE: To describe on-site veterinary medical care for working dogs and horses deployed for the 2012 Republican National Convention (RNC) in Tampa, Fla, August 24 to 30, 2012. DESIGN: Retrospective case series. SAMPLE: 130 dogs and 45 horses. PROCEDURES: Data collected included breed, age, history, task assignment, reason for evaluation, and physical examination findings. A patient encounter report was recorded each time an animal was seen by veterinary staff for a physical evaluation...
September 1, 2015: Journal of the American Veterinary Medical Association
H Meyer-Lueckel, R J Wierichs, B Gninka, P Heldmann, C E Dörfer, S Paris
OBJECTIVES: The aim of this exploratory double-blinded, randomized, cross-over, in situ study was to compare the effects of various model parameters ('intervention', 'brushing', 'position') on enamel caries lesions in a dose-response model. METHODS: In each of four experimental legs of four weeks 16 participants wore intraoral mandibular appliances with four 'plaque-retaining' and four 'easily cleanable' positioned pre-demineralized bovine enamel specimens in the vestibular flanges mimicking proximal and buccal surfaces, respectively (n=512)...
October 2015: Journal of Dentistry
Ahmed Awadein, Dina El-Fayoumi
PURPOSE: To evaluate the results of ipsilateral inferior rectus (IR) recession, when performed alone or in combination with contralateral superior rectus (SR) recession in patients with monocular elevation deficiency (MED) and IR tightness. METHODS: The medical records of patients with MED and tight IR muscle were retrospectively reviewed. Patients underwent either ipsilateral IR recession alone (IR group) or combined with contralateral SR recession (IR+SR group)...
August 2015: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Akio Takayanagi, Masanori Sasaki, Yuko Kataoka-Sasaki, Ko Kobayashi, Yohei Matsuda, Shinichi Oka, Naoya Masumori, Jeffery D Kocsis, Osamu Honmou
INTRODUCTION: We evaluated the potential preventive effects and mechanisms of intravenously preloaded mesenchymal stem cells (MSCs) for erectile dysfunction (ED) in a cavernous nerve (CN) injury model. METHODS: Male Sprague-Dawley (SD) rats were used for this study. Rats were randomized into two groups. One group was intravenously preloaded with MSCs (1.0 × 10(6) cells in 1 mL total fluid volume) and the other was infused with medium alone (1 mL Dulbecco's modified Eagle's medium [DMEM]) for sham control, respectively...
August 2015: Journal of Sexual Medicine
Michail E Keramidas, Stylianos N Kounalakis, Ola Eiken, Igor B Mekjavic
The study examined the effects of two short-term, intermittent hypoxic training protocols, namely exercising in hypoxia and living in normoxia (LL-TH; n=8), and exercising in normoxia preceded by a series of brief intermittent hypoxic exposures at rest (IHE+NOR; n=8), on the finger temperature response during a sea-level local cold test. In addition, a normoxic group was assigned as a control group (NOR; n=8). All groups trained on a cycle-ergometer 1 h/day, 5 days/week for 4 weeks at 50% of peak power output...
September 2015: High Altitude Medicine & Biology
Caitlin B L Magraw, Rachel Garaas, Alan Shaw, Ceib Phillips, Timothy A Turvey
OBJECTIVE: The Kufner modified Le Fort III osteotomy (LFIII) can be used to address midface deficiency, which is often accompanied by excessive scleral exposure. The purpose of this project is to analyze the changes in scleral exposure after a LFIII. METHODS: Thirteen patients with midface hypoplasia were treated with LFIII. Scleral surface area (SSA) was determined by pixel count and the distance from the inferior eyelid margin to the center of the pupil (MED) was measured pre- and postoperatively...
August 2015: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Yibin Xie, Qi Yang, Guoxi Xie, Jianing Pang, Zhaoyang Fan, Debiao Li
PURPOSE: The purpose of this study was to develop a three-dimensional black blood imaging method for simultaneously evaluating the carotid and intracranial arterial vessel walls with high spatial resolution and excellent blood suppression with and without contrast enhancement. METHODS: The delay alternating with nutation for tailored excitation (DANTE) preparation module was incorporated into three-dimensional variable flip angle turbo spin echo (SPACE) sequence to improve blood signal suppression...
June 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
Tudor A Codreanu, Antonio Celenza, Ali A Rahman Alabdulkarim
UNLABELLED: Introduction The effect on behavioral change of educational programs developed to reduce the community's disaster informational vulnerability is not known. This study describes the relationship of disaster education, age, sex, and country-specific characteristics with students discussing disasters with friends and family, a measure of proactive behavioral change in disaster preparedness. METHODS: Three thousand eight hundred twenty-nine final year high school students were enrolled in an international, multi-center prospective, cross-sectional study using a pre-validated written questionnaire...
August 2015: Prehospital and Disaster Medicine
Jessica Yu, Amy Hosmer, Tamara Parks, Christopher J Sonnenday, Pratima Sharma
UNLABELLED: Hospitalizations after solid organ transplantation may affect patient outcomes. Identification of the factors attributed to them may decrease hospitalization rates, reduce overall cost, and improve post-transplant outcomes. We examined the risk factors for early hospitalization within 30 and 90 days after liver transplantation (LT). METHODS: Data on all deceased donor LT recipients (age ≥18 years) transplanted between 2/28/2002-2/27/2007 and discharged alive from the index hospitalization within 30 days of LT were collected (N = 267)...
November 2015: Digestive Diseases and Sciences
Ramokone L Lebelo, Sofie Thys, Ina Benoy, Christophe E Depuydt, John-Paul Bogers, Meshack N Bida, M Jeffrey Mphahlele
The aim of the study was to identify specific human papillomavirus (HPV) type responsible for malignancy in penile tissue samples using laser micro-dissection and TaqMan quantitative real-time PCR (qPCR). The study was based on two pre-malignant and seven malignant penile tissue samples and laser micro-dissection was performed on all. Genotyping was performed on whole tissue sections and laser micro-dissection samples using qPCR. Two whole tissue section samples were HPV negative while seven were HPV positive...
October 2015: Journal of Medical Virology
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